Genentech: Publications

March 6, 1998

High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the TrK receptors

Journal of Biological Chemistry, ISSN: 00219258

Urfer; Tsoulfas; O'Connell; Hongo; Wei Zhao; Presta

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March 6, 1998

Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein

Journal of Biological Chemistry, ISSN: 00219258

Yan Wu; Spencer; Lasky

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March 5, 1998

Ammonium ion and glucosamine dependent increases of oligosaccharide complexity in recombinant glycoproteins secreted from cultivated BHK-21 cells

Biotechnology and Bioengineering, ISSN: 00063592

Martin Gawlitzek; Ulrich Valley; Roland Wagner

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March 1, 1998

Prebeta-1 HDL in plasma of normolipidemic individuals: Influences of plasma lipoproteins, age, and gender

Journal of Lipid Research, ISSN: 00222275

Patricia M. O'Connor; Zysow; Schoenhaus; Ishida; Kunitake; Naya-Vigne; Duchateau; Redberg; Susan J. Spencer; Mark; Mazur; Heilbron; Jaffe; Malloy; Kane

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March 1, 1998

Establishment of conditionally immortalized rat utricular epithelial cell lines using a retrovirus-mediated gene transfer technique

Hearing Research, ISSN: 03785955

Zheng; Lewis; Gao

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February 17, 1998

Pharmacokinetics and pharmacodynamics of recombinant tissue-type plasminogen activator following intravenous administration in rabbits: A comparison of three dosing regimens

Biopharmaceutics and Drug Disposition, ISSN: 01422782

Stephen M. Eppler; Tauri D. Senn; Ellen Gilkerson; Modi

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February 16, 1998

The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor

Journal of Experimental Medicine, ISSN: 00221007

Spencer; Francesco Di Marco; Jeff Hooley; Sharon Pitts-Meek; Michele Bauer; Anne Ryan; Bernard Sordat; Gibbs; Michel Aguet

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February 15, 1998

Structure-function study of the extracellular domain of the human IFN- α receptor (hIFNAR1) using blocking monoclonal antibodies: The role of domains 1 and 2

Journal of Immunology, ISSN: 00221767

Lu; Anan Chuntharapai; Joanne T. Beck; Bass; Ow; De Vos; Gibbs; K.Jin Kim

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February 15, 1998

Structure-function study of the extracellular domain of the human IFN- α receptor (hIFNAR1) using blocking monoclonal antibodies: The role of domains 1 and 2

Journal of Immunology, ISSN: 00221767

Lu; Anan Chuntharapai; Joanne Beck; Bass; Ow; De Vos; Gibbs; K.Jin Kim

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February 13, 1998

A novel soluble tissue factor variant with an altered factor VIIa binding interface

Journal of Biological Chemistry, ISSN: 00219258

Geoffrey F. Lee; Robert F. Kelley

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February 6, 1998

Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stability

Journal of Biological Chemistry, ISSN: 00219258

Terri Davis-Smyth; Presta; Napoleone Ferrara

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February 5, 1998

Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain

Nature Structural Biology, ISSN: 10728368

Mikael Akke; Jun Liu; John Cavanagh; Harold P. Erickson; Arthur G. Palmer III

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February 5, 1998

Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase

Nature Structural Biology, ISSN: 10728368

Jane Gitschier; Moffat; Dorothea Reilly; William I. Wood; Wayne J. Fairbrother

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February 3, 1998

Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: The case for paracrine amplification of angiogenesis

Circulation, ISSN: 00097322

Eric Van Belle; Bernhard Witzenbichler; Donghui Chen; Marcy Silver; Ling Chang; Ralph H. Schwall; Jeffrey M. Isner

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February 3, 1998

Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial

Circulation, ISSN: 00097322

Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott A. Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald

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February 3, 1998

Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial

Circulation, ISSN: 00097322

Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald

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February 1, 1998

Synergistic effects of Schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1)

Journal of Neuroscience, ISSN: 02706474

Vilma Arce; Richard A. Pollock; Jean-Marc Philippe; Diane Pennica; Christopher E. Henderson; Odile Delapeyrière

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February 1, 1998

Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages

European Journal of Neuroscience, ISSN: 0953816X

Antony Horton; Perry F. Bartlett; Diane Pennica; Alun M. Davies

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February 1, 1998

An oligopeptide transporter is expressed at high levels in the pancreatic carcinoma cell lines AsPc-1 and Capan-2

Cancer Research, ISSN: 00085472

Deborah E. Gonzalez; Kuang-Ming Y. Covitz; Wolfgang Sadée; Mrsny

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February 1, 1998

Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis

Pediatric Pulmonology, ISSN: 87556863

David E. Geller; Howard Eigen; Stanley B. Fiel; Clark; André P. Lamarre; Charles A. Johnson; Michael W. Konstan

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February 1, 1998

Disruption of a putative SH3 domain and the proline-rich motifs in the 53-kDa substrate of the insulin receptor kinase does not alter its subcellular localization or ability to serve as a substrate

Journal of Cellular Biochemistry, ISSN: 07302312

Tammie C. Yeh; Wenlu Li; Gilbert-Andre Keller; Richard A. Roth

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January 30, 1998

An induced proximity model for caspase-8 activation

Journal of Biological Chemistry, ISSN: 00219258

Marta Muzio; Brent R. Stockwell; Henning R. Stennicke; Guy S. Salvesen; Vishva M. Dixit

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January 26, 1998

Probing the structural basis of the catalytic activity of HIV-1 PR through total chemical protein synthesis

Journal of Molecular Structure: THEOCHEM, ISSN: 01661280

Maria Miller; Baca; J.K. Mohana Rao; Stephen B. H. Kent

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January 22, 1998

Calcium-dependent Ret activation by GDNF and neurturin

Oncogene, ISSN: 09509232

Chika Nozaki; Naoya Asai; Hideki Murakami; Toshihide Iwashita; Yosuke Iwata; Keizo Horibe; Robert D. Klein; Rosenthal; Masahide Takahashi

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January 15, 1998

Adenovector-mediated expression of human thrombopoietin cDNA in immune- compromised mice: Insights into the pathophysiology of osteomyelofibrosis

Journal of Immunology, ISSN: 00221767

Beat M. Frey; Shahin Rafii; Michael Teterson; Dan L. Eaton; Crystal; Malcolm A.S. Moore

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January 9, 1998

Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein

Journal of Biological Chemistry, ISSN: 00219258

Dowbenko; Spencer; Quan; Lasky

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January 9, 1998

Photoaffinity labeling by 4-thiodideoxyuridine triphosphate of the HIV- 1 reverse transcriptase active site during synthesis. Sequence of the unique labeled hexapeptide

Journal of Biological Chemistry, ISSN: 00219258

Shanhua Lin; William J. Henzel; Sunil Nayak; Don Dennis

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January 2, 1998

Identification of an inhibin receptor in gonadal tumors from inhibin α- subunit knockout mice

Journal of Biological Chemistry, ISSN: 00219258

Lawrence B. Draper; Matzuk; Veronica J. Roberts; Edward T. Cox; Jeffrey Weiss; Mather; Woodruff

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January 1, 1998

Development of a single-shot subunit vaccine for HIV-1. 5. Programmable in vivo autoboost and long lasting neutralizing response

Journal of Pharmaceutical Sciences, ISSN: 00223549

Cleland; Lim; Daugherty; Barron; Noelyn Desardin; Duenas; Eastman; Vennari; Wrin; Berman; Michael Powel

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January 1, 1998

Adaptation to hyperglycemia enhances insulin secretion in glucokinase mutant mice

Diabetes, ISSN: 00121797

Seamus K. Sreenan; Brian N. Cockburn; Aaron C. Baldwin; Diane M. Ostrega; Matteo Levisetti; Andrew Grupe; Graeme I. Bell; Stewart; Michael W. Roe; Kenneth S. Polonsky

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January 1, 1998

Raw materials as a source of contamination in large-scale cell culture.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick

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January 1, 1998

Biological response to ErbB ligands in nontransformed cell lines correlates with a specific pattern of receptor expression

Endocrinology, ISSN: 00137227

Sundaresan; Penelope E. Roberts; King; Mark X. Sliwkowski; Mather

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January 1, 1998

Therapeutic potential of neurotrophins for treatment of hearing loss

Molecular Neurobiology, ISSN: 08937648

Gao

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January 1, 1998

The dormant in vivo phenotype of early stage primary human melanoma: Termination by overexpression of vascular endothelial growth factor

Angiogenesis, ISSN: 09696970

Liisa Bayko; Janusz Rak; Shan Man; Roy Bicknell; Napoleone Ferrara; Robert S. Kerbel

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January 1, 1998

Real-time measurement of lysis of mural platelet deposits by fibrinolytic agents under arterial flow

Annals of Biomedical Engineering, ISSN: 00906964

Dionne A. Graham; Trevor C. Huang; Keyt; B. Rita Alevriadou

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January 1, 1998

Purification and Physical Characterization of Cloned Human cAMP Phosphodiesterases PDE-4D and -4C

Cell Biochemistry and Biophysics, ISSN: 10859195

Natalie Saldou; Preston A. Baecker; Bin Li; Zhengyu Yuan; Rena Obernolte; James Ratzliff; Eric Osen; Kurt Jarnagin; Earl R. Shelton

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January 1, 1998

Making informed choices: Medium, serum, and serum-free medium how to choose the appropriate medium and culture system for the model you wish to create

Methods in Cell Biology, ISSN: 0091679X

Mather

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January 1, 1998

Preparation and biological activity of novel tricyclic GPIIb/IIIa antagonists

Bioorganic and Medicinal Chemistry, ISSN: 09680896

Kirk D. Robarge; Dina; Todd C. Somers; Arthur Lee; Thomas E. Rawson; Alan G. Olivero; Maureen Tischler; Robert R. Webb II; Kenneth J Weese; Ignacio Aliagas; Brent Blackburn

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January 1, 1998

Evaluation of product comparability.

Developments in biological standardization, ISSN: 03015149

Stuart E. Builder

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January 1, 1998

Periodontal repair in dogs: Effect of recombinant human transforming growth factor-β1 on guided tissue regeneration

Journal of Clinical Periodontology, ISSN: 03036979

Ulf M. E. Wikesjö; Saghi S. Razi; Thorarinn J. Sigurdsson; Dimitris N. Tatakis; Michael B. Lee; Ongpipattanakul; Tue H. Nguyen; Ross Hardwick

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January 1, 1998