Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12351 - 12400 OF 15572 RESULTS

A new continuous alternation task in T-maze detects hippocampal dysfunction in mice: A strain comparison and lesion study
Behavioural Brain Research, ISSN: 01664328
Gerlai
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Statistical methods for assessing differential vaccine protection against human immunodeficiency virus types
Biometrics, ISSN: 0006341X
Peter B. Gilbert; Steven G. Self; Ashby
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Peptide degradation during preparation and in vitro release testing of poly(L-lactic acid) and poly(DL-lactic-co-glycolic acid) microparticles
International Journal of Pharmaceutics, ISSN: 03785173
Claudia Witschi; Eric Doelker
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Death receptors: Signaling and modulation
Science, ISSN: 00368075
Avi Ashkenazi; Vishva M. Dixit
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Src-like adaptor protein (Slap) is a negative regulator of mitogenesis
Current Biology, ISSN: 09609822
Serge Roche; Gema Alonso; Andrius Kazlauskas; Vishva M. Dixit; Courtneidge; Akhilesh Pandey
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Tumor necrosis factor-α regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells
Journal of Biological Chemistry, ISSN: 00219258
Enrico Giraudo; Luca Primo; Enrica Audero; Hans-Peter Gerber; Pieter Koolwijk; Shay Soker; Michael Klagsbrun; Napoleone Ferrara; Federico Bussolino
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Sweet success with tethered enzyme catalysis
Nature Biotechnology, ISSN: 10870156
Warner
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Synergistic activation of the germline ε promoter mediated by Stat6 and C/EPBβ
Journal of Immunology, ISSN: 00221767
Thomas Mikita; Masae Kurama; Ulrike Schindler
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Synthesis and screening of linear and cyclic oligocarbamate libraries. Discovery of high affinity ligands for GPIIb/IIIa
Journal of the American Chemical Society, ISSN: 00027863
Charles Y. Cho; R. Scott Youngquist; Sari J. Paikoff; Beresini; Andrea Hebert; Lea Berleau; Corey W. Liu; David E. Wemmer; Thomas Keough; Peter G. Schultz
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Pharmacodynamics of recombinant human DNASE I in serum
Clinical and Experimental Immunology, ISSN: 00099104
Prince; Baker; Dodge; Ahmed; Chestnut; Sinicropi
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Biochemical and morphometric analyses show that myelination in the insulin-like growth factor 1 null brain is proportionate to its neuronal composition
Journal of Neuroscience, ISSN: 02706474
Clara M. Cheng; George Joncas; Rickey R. Reinhardt; Robert Farrer; Richard Quarles; Jeremy Janssen; Michael P. McDonald; Jacqueline N. Crawley; Powell-Braxton; Carolyn Bondy
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A mouse model of human familial hypercholesterolemia: Markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet
Nature Medicine, ISSN: 10788956
Powell-Braxton; Murielle Véniant; Richard D. Latvala; Ken-Ichi Hirano; Wesley B. Won; Ross; Noel Dybdal; Constance Zlot; Stephen G. Young; Nicholas O. Davidson
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Use of angiotensin-converting enzyme inhibitors at discharge in patients with acute myocardial infarction in the United States: Data from the National Registry of Myocardial Infarction 2
Journal of the American College of Cardiology, ISSN: 07351097
Hal V. Barron; Andrew D. Michaels; Charles Maynard|; Nathan R. Every
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Response to growth hormone in attention deficit hyperactivity disorder: Effects of methylphenidate and pemoline therapy
Pediatrics, ISSN: 00314005
Jayashree K. Rao; Joanne R. Julius; Timothy J. Breen; Sandra L. Blethen
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Hematopoietic stem cell maintenance and differentiation are supported by embryonic aorta-gonad-mesonephros region-derived endothelium
Blood, ISSN: 00064971
Osamu Ohneda; Christopher Fennie; Zhong Zheng; Christopher J. Donahue; Hank La; Ricardo Villacorta; Cairns; Lasky
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Current dosing of growth hormone in children with growth hormone deficiency: How physiologic?
Pediatrics, ISSN: 00314005
Margaret H. Macgillivray; Sandra L. Blethen; John G. Buchlis; Richard R. Clopper; David E. Sandberg; Thomas A. Conboy
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Adult height in children with growth hormone deficiency who are treated with biosynthetic growth hormone: The national cooperative growth study experience
Pediatrics, ISSN: 00314005
Gilbert P. August; Joanne R. Julius; Sandra L. Blethen
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Lack of correlation between growth hormone provocative test results and subsequent growth rates during growth hormone therapy
Pediatrics, ISSN: 00314005
Jennifer J. Bell; Ken Dana
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The role of serial sampling in the diagnosis of growth hormone deficiency
Pediatrics, ISSN: 00314005
Frank B. Diamond; E. Verena Jorgensen; Allen W. Root; Dorothy I. Shulman; Judy P. Sy; Sandra L. Blethen; Barry B. Bercu
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Increased expression of cyclin G1 and p21(WAF1/CIP1) in neurons following transient forebrain ischemia: Comparison with early DNA damage
Journal of Neuroscience Research, ISSN: 03604012
Menno Van Lookeren Campagne; Ramanjit Gill
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Growth hormone treatment of girls with Turner syndrome: The national cooperative growth study experience
Pediatrics, ISSN: 00314005
Plotnick; Kenneth M. Attie; Sandra L. Blethen; Judy P. Sy
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Aminoguanidinium(2+) Hexafluorozirconate Monohydrate: A Co-Product of Preparing the Ferroelectric Anhydrous Salt
Acta Crystallographica Section B: Structural Science, ISSN: 01087681
Ross II; Paulsen; Nielson; Abrahams
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Optimizing estrogen replacement treatment in Turner syndrome
Pediatrics, ISSN: 00314005
Rosenfield; Nancy Perovic; Nancy Devine; Nelly Mauras; Thomas Moshang Jr.; Allen W. Root; Judy P. Sy
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Cloning and characterization of an actin-resistant DNase I-like endonuclease secreted by macrophages
Gene, ISSN: 03781119
Will F. Baron; Clark Q. Pan; Steven A. Spencer; Anne Ryan; Lazarus; Kevin Baker
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Molecular cloning and characterization of human and murine DNase II
Gene, ISSN: 03781119
Kevin Baker; Will F. Baron; William J. Henzel; Steven A. Spencer
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Tumor-suppressor p53 is expressed in proliferating and newly formed neurons of the embryonic and postnatal rat brain: Comparison with expression of the cell cycle regulators p21(Waf1/Cip1), p27(Kip1), p57(Kip2), p16(Ink4a), cyclin G1, and the proto-oncogene Bax
Journal of Comparative Neurology, ISSN: 00219967
Menno Van Lookeren Campagne; Ramanjit Gill
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Blockade of both L-selectin and α4 integrins abrogates naive CD4 cell trafficking and responses in gut-associated lymphoid organs
International Immunology, ISSN: 09538178
Linda M. Bradley; Mary E. Malo; Sherman Fong; Susan L. Tonkonogy; Susan R. Watson
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Identification and functional characterization of DR6, a novel death domain-containing TNF receptor
FEBS Letters, ISSN: 00145793
Pan; Johannes H. Bauer; Valsala Haridas; Shuxia Wang; Ding Liu; Guoliang Yu; Claudius Vincenz; Aggarwal; Jian Ni; Vishva M. Dixit
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Blockade of both L-selectin and α4 integrins abrogates naive CD4 cell trafficking and responses in gut-associated lymphoid organs
International Immunology, ISSN: 09538178
Linda M. Bradley; Mary E. Malo; Fong; Susan L. Tonkonogy; Susan R. Watson
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Improved potency of hyperactive and actin-resistant human DNase I variants for treatment of cystic fibrosis and systemic lupus erythematosus
Journal of Biological Chemistry, ISSN: 00219258
Clark Q. Pan; Tony H. Dodge; Baker; Prince; Sinicropi; Lazarus
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Oligopeptide transporters as putative therapeutic targets for cancer cells
Pharmaceutical Research, ISSN: 07248741
Mrsny
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Altered spatial learning and memory in mice lacking the mGluR4 subtype of metabotropic glutamate receptor
Behavioral Neuroscience, ISSN: 07357044
Gerlai; John C. Roder; David R. Hampson
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Insulin-like growth factor-1 but not growth hormone augments mammalian myocardial contractility by sensitizing the myofilament to Ca2+ through a wortmannin-sensitive pathway: Studies in rat and ferret isolated muscles
Circulation Research, ISSN: 00097330
Antonio Cittadini; Yoshiki Ishiguro; Hinrik Strömer; Matthias Spindler; Alan C. Moses; Ross Clark; Pamela Douglas; Joanne S. Ingwall; James P. Morgan
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Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4
FEBS Letters, ISSN: 00145793
V. Danial Fitzpatrick; Paul Pisacane; Richard L. Vandlen; Mark X. Sliwkowski
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The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease
Journal of Biological Chemistry, ISSN: 00219258
Divya Chaudhary; Karen M. O'Rourke; Arul M. Chinnaiyan; Vishva M. Dixit
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Experimental autoimmune encephalomyelitis induced with a combination of myelin basic protein and myelin oligodendrocyte glycoprotein is ameliorated by administration of a single myelin basic protein peptide
Journal of Immunology, ISSN: 00221767
Elizabeth A. Leadbetter; Cheryl R. Bourque; Devaux; Carl D. Olson; Geoffrey H. Sunshine; Shirish Hirani; Barbara P. Wallner; Dawn E. Smilek; Mary Pat Happ
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Role of c-mpl in early hematopoiesis
Blood, ISSN: 00064971
Gregg Solar; William G. Kerr; Francis C. Zeigler; Darren Hess; Christopher J. Donahue; Frederic J. De Sauvage; Dan L. Eaton
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An efficient route to human bispecific IgG
Nature Biotechnology, ISSN: 10870156
A. Margaret Merchant; Zhu; Jean Q. Yuan; Goddard; Adams; Presta; Paul J. Carter
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Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons
Journal of Neuroscience, ISSN: 02706474
Brian A. Horger; Merry Nishimura; Armanini; Li-Chong Wang; Kris Poulsen; Carl Rosenblad; Deniz Kirik; Moffat; Laura C. Simmons; Eugene M. Johnson Jr.; Jeffrey Milbrandt; Rosenthal; Anders Bjorklund; Richard L. Vandlen; Mary Hynes; Phillips
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Susceptibility to Pneumocystis carinii in mice is dependent on simultaneous deletion of IFN-γ and type 1 and 2 TNF receptor genes
Journal of Immunology, ISSN: 00221767
Daniel G. Rudmann; Angela M. Preston; Mark Moore; James M. Beck
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Contribution of domain interface residues to the stability of antibody C(H)3 domain homodimers
Biochemistry, ISSN: 00062960
William Dall'Acqua; Alexander L. Simon; Michael G. Mulkerrin; Paul J. Carter
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Backbone dynamics of the EGF-like domain of heregulin-α
Journal of Molecular Biology, ISSN: 00222836
Wayne J. Fairbrother; Jun Liu; Paul Pisacane; Mark X. Sliwkowski; Arthur G. Palmer III
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Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders
Pharmaceutical Research, ISSN: 07248741
Maa; Phuong-Anh Nguyen; Andya; Nancy Dasovich; Sweeney; Steven J. Shire; Chung C. Hsu
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Molecular mimics of insulin-like growth factor 1 (IGF-1) for inhibiting IGF-I: IGF-binding protein interactions
Biochemistry, ISSN: 00062960
Henry B. Lowman; Chen; Nicholas J. Skelton; Deborah L. Mortensen; Elizabeth Tomlinson; Michael D Sadick; Icaf Robinson; Ross Clark
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DNAse treatment does not improve the survival of lupus prone (NZB x NZW)F1 mice
Lupus, ISSN: 09612033
Verthelyi; Noel Dybdal; Kathleen A. Elias; Klinman
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ERICE, a novel FLICE-activatable caspase
Journal of Biological Chemistry, ISSN: 00219258
Eric W. Humke; Jian Ni; Vishva M. Dixit
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Modulations in lipid A and phospholipid biosynthesis pathways influence outer membrane protein assembly in Escherichia coli K-12
Molecular Microbiology, ISSN: 0950382X
Andrew Kloser; Mike Laird; Ming Deng; Rajeev Misra
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Retrovirus-mediated in vivo gene transfer in the replicating liver using recombinant hepatocyte growth factor without liver injury or partial hepatectomy
Human Gene Therapy, ISSN: 10430342
Ken-Ichiro Kosai; Finegold; Bich-Thuy Thi-Huynh; Margaret Tewson; Ching-Nan; Neil Bowles; Savio L. C. Woo; Ralph H. Schwall; Gretchen J. Darlington
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The treatment of metastatic renal cell carcinoma patients with recombinant human gamma interferon
Cancer Journal from Scientific American, ISSN: 10814442
Small; Geoffrey R. Weiss; Umme K. Malik; Philip J. Walther; David H. Johnson; George Wilding; Timothy Kuzel; Alex Bajamonde; Virginia Paton
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Total chemical synthesis of bovine pancreatic trypsin inhibitor by native chemical ligation
FEBS Letters, ISSN: 00145793
Wuyuan Lu; Melissa A. Starovasnik; Stephen B. H. Kent
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