Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12401 - 12450 OF 15217 RESULTS

April 15, 1997

Bone Marrow Can Function as a Lymphoid Organ during a Primary Immune Response under Conditions of Disrupted Lymphocyte Trafficking

Journal of Immunology, ISSN: 00221767

Ralph A. Tripp; David J. Topham; Susan R. Watson; Peter C. Doherty

April 8, 1997

Nuclear transport of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in opossum kidney cells

Endocrinology, ISSN: 00137227

Wenlu Li; Janet Fawcett; Widmer; Fielder; Ralph Rabkin; Gilbert-Andre Keller

April 4, 1997

Metal-catalyzed oxidation of histidine in human growth hormone: Mechanism, isotope effects, and inhibition by a mild denaturing alcohol

Journal of Biological Chemistry, ISSN: 00219258

Fang Zhao; Elena Ghezzo-Schöneich; Gaby I. Aced; Jinyang Hong; Terry Milby; Christian Schöneich

April 1, 1997

Preparation and characterization of PEGylated human growth hormone and human growth hormone mutants

American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, ISSN: 00323934

Olson; Richard L. Gehant; Mukku; Kathy L. O'Connell; Brandon Tomlinson; Klara Totpal; Winkler

April 1, 1997

Remarkable sequence conservation of transcripts encoding amphibian and mammalian homologues of quaking, a KH domain RNA-binding protein

Gene, ISSN: 03781119

Aaron M. Zorn; Matthew Grow; Kristin D. Patterson; Tom A. Ebersole; Qi Chen; Karen Artzt; Paul A. Krieg

April 1, 1997

Growth hormone attenuates early left ventricular remodeling and improves cardiac function in rats with large myocardial infarction

Journal of the American College of Cardiology, ISSN: 07351097

Antonio Cittadini; Jessica D. Grossman; Raffaele Napoli; Sarah E. Katz; Hinrik Strömer; Robert J. Smith; Ross Clark; James P. Morgan; Pamela Douglas

April 1, 1997

Anarchy of the macrophage reaction: Endotoxins and sepsis Anarchie der Makrophagenreaktion Endotoxine und Sepsis

Krankenhauspharmazie, ISSN: 01737597

Ralf R. Schumann

April 1, 1997

Immunocytochemical localization of O2-sensing protein (NADPH oxidase) in chemoreceptor cells

Microscopy Research and Technique, ISSN: 1059910X

Youngson; Nurse; Yeger; John T. Curnutte; Vollmer; Wong; Cutz

March 28, 1997

A non-radioactive complement-dependent cytotoxicity assay for anti-CD20 monoclonal antibody

Journal of Immunological Methods, ISSN: 00221759

Hélène Gazzano-Santoro; Peter Ralph; Thomas C. Ryskamp; Chen; Mukku

March 20, 1997

Feasibility of protein spray coating using a fluid-bed Wurster processor

Biotechnology and Bioengineering, ISSN: 00063592

Maa; Chung C. Hsu

March 15, 1997

Expression of Chemokine Receptors by Subsets of Neurons in the Central Nervous System

Journal of Immunology, ISSN: 00221767

Richard Horuk; Alvin W. Martin; Zi-Xuan Wang; Laura Schweitzer; Alexandra Gerassimides; Haihong Guo; Zhao-Hai Lu; Joseph Hesselgesser; H. Daniel Perez; Jin Kim; Joseph Parker; Hadley; Stephen C. Peiper

March 14, 1997

A novel protein-tyrosine phosphatase related to the homotypically adhering κ and μ receptors

Journal of Biological Chemistry, ISSN: 00219258

Jill Cheng; Kai Wu; Armanini; Nancy A. O'Rourke; Dowbenko; Lasky

March 10, 1997

The role of nerve growth factor in a model of visceral inflammation

Neuroscience, ISSN: 03064522

Dmitrieva; David L. Shelton; Rice; McMahon

March 1, 1997

The prehospital electrocardiogram in acute myocardial infarction: Is its full potential being realized?

Journal of the American College of Cardiology, ISSN: 07351097

John G. Canto; William J. Rogers; Laura J. Bowlby; William J. French; Douglas J. Pearce; Douglas Weaver

March 1, 1997

Neurotrophin-3- and norepinephrine-mediated adrenergic differentiation and the inhibitory action of desipramine and cocaine

Journal of Neurobiology, ISSN: 00223034

Jian-Min Zhang; Jessica Dix; Carol J. Langtimm-Sedlak; Thomas Trusk; Brett Schroeder; Raymond Hoffmann; Aldo D. Strosberg; Winslow; Maya Sieber-Blum

March 1, 1997

Identification of mouse liver proteins on two-dimensional electrophoresis gels by matrix-assisted laser desorption/ionization mass spectrometry of in situ enzymatic digests

Electrophoresis, ISSN: 01730835

Kathy L. O'Connell; Stults

March 1, 1997

Postmitotic neurons migrate tangentially in the cortical ventricular zone

Development (Cambridge), ISSN: 09501991

Nancy A. O'Rourke; Anjen Chenn; Susan K. McConnell

February 28, 1997

AL-1-induced growth cone collapse of rat cortical neurons is correlated with REK7 expression and rearrangement of the actin cytoskeleton

European Journal of Neuroscience, ISSN: 0953816X

Caras

February 28, 1997

Role of high-performance liquid chromatographic protein analysis in developing fermentation processes for recombinant human growth hormone, relaxin, antibody fragments and lymphotoxin

Journal of Chromatography A, ISSN: 00219673

Fredric S. Jacobson; John Hanson; Pin-Yee Wong; Michael G. Mulkerrin; James Deveney; Dorothea Reilly; Susan C. Wong

February 28, 1997

From peptide to non-peptide. 3. Atropisomerie GPIIbIIIa antagonists containing the 3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione nucleus

Journal of Medicinal Chemistry, ISSN: 00222623

Brent Blackburn; Arthur Lee; Mark Baier; Benjamin Kohl; Alan G. Olivero; Regina Matamoros; Kirk D. Robarge; Robert S. McDowell

February 21, 1997

Model peptide studies demonstrate that amphipathic secondary structures can be recognized by the chaperonin GroEL (cpn60)

Journal of Biological Chemistry, ISSN: 00219258

Bill T. Brazil; Cleland; Robert S. McDowell; Nicholas J. Skelton; Kenneth J. Paris; Paul M. Horowitz

February 21, 1997

Signaling of the cardiotrophin-1 receptor: Evidence for a third receptor component

Journal of Biological Chemistry, ISSN: 00219258

Olivier Robledo; Maryvonne Fourcin; Sylvie Chevalier; Catherine Guillet; Patrick Auguste; Annick Pouplard-Barthelaix; Diane Pennica; Hugues Gascan

February 20, 1997

CRF2-4: Isolation of cDNA clones encoding the human and mouse proteins

Gene, ISSN: 03781119

Gibbs; Diane Pennica

February 17, 1997

Heterogeneity of serum albumin samples with respect to solid-state aggregation via thiol-disulfide interchange - Implications for sustained release from polymers

Journal of Controlled Release, ISSN: 01683659

Henry R. Costantino; Lisa Shieh; Klibanov; Langer

February 17, 1997

Thrombopoietin: The primary regulator of megakaryocytopoiesis and thrombopoiesis

Experimental Hematology, ISSN: 0301472X

Dan L. Eaton; Frederic J. De Sauvage

February 11, 1997

Biochemical characterization of recombinant fusions of lipopolysaccharide binding protein and bactericidal/permeability-increasing protein. Implications in biological activity

Journal of Biological Chemistry, ISSN: 00219258

Susan L. Abrahamson; Hsiu-Mei Wu; Robert E. Williams; Ken Der; Nneka Ottah; Roger Little; Hélène Gazzano-Santoro; Georgia Theofan; Bauer; Scott Leigh; Anne Orme; Arnold H. Horwitz; Stephen F. Carroll; Russell L Dedrick

February 5, 1997

On the pH memory of lyophilized compounds containing protein functional groups

Biotechnology and Bioengineering, ISSN: 00063592

Henry R. Costantino; Kai Griebenow; Langer; Klibanov

February 1, 1997

Chemoattractant Cross-Desensitization of the Human Neutrophil IL-8 Receptor Involves Receptor Internalization and Differential Receptor Subtype Regulation

Journal of Immunology, ISSN: 00221767

Ian Sabroe; Timothy J. Williams; Hébert; Paul D. Collins

February 1, 1997

Isolation and characterization of the platelet-derived growth factor beta receptor promoter

Developmental Dynamics, ISSN: 10588388

Eve Shinbrot; Xiang Liao; Williams

February 1, 1997

Down-Regulation of FcεRI Expression on Human Basophils during in Vivo Treatment of Atopic Patients with Anti-IgE Antibody

Journal of Immunology, ISSN: 00221767

Donald W. Macglashan Jr.; Bruce S. Bochner; Daniel C. Adelman; Paula Jardieu; Alkis Togias; Jane McKenzie-White; Sherry A. Sterbinsky; Robert G. Hamilton; Lawrence M. Lichtenstein

February 1, 1997

Association of Csk-homologous kinase (CHK) (formerly MATK) with HER- 2/ErbB-2 in breast cancer cells

Journal of Biological Chemistry, ISSN: 00219258

Sheila Zrihan-Licht; Jinkyu Lim; Iafa Keydar; Mark X. Sliwkowski; Jerome E. Groopman; Hava Avraham

February 1, 1997

Respective role of TNF receptors in the development of experimental cerebral malaria

Journal of Neuroimmunology, ISSN: 01655728

Rudolf Lucas; Jin-Ning Lou; Pierre Juillard; Mark Moore; Horst Bluethmann; Georges E. Grau

January 22, 1997

A general method for constraining short peptides to an α-helical conformation

Journal of the American Chemical Society, ISSN: 00027863

J. Christopher Phelan; Nicholas J. Skelton; Andrew Braisted; Robert S. McDowell

January 15, 1997

The effect of chemical modifications on octanol/water partition (log D) and permeabilities across Caco-2 monolayers

Advanced Drug Delivery Reviews, ISSN: 0169409X

Rubas; Cromwell

January 15, 1997

Metal-catalyzed photooxidation of histidine in human growth hormone

Analytical Biochemistry, ISSN: 00032697

Suh Chang; Glen Teshima; Terry Milby; Beth Gillece-Castro; Eleanor Canova-Davis

January 7, 1997

Sterically stabilized anti-HER2 immunoliposomes: Design and targeting to human breast cancer cells in vitro

Biochemistry, ISSN: 00062960

Dmitri Kirpotin; Park; Hong; Samuel Zalipsky; Wenlu Li; Paul J. Carter; Benz; Papahadjopoulos

January 1, 1997

Specification and Survival of Dopaminergic Neurons in the Mammalian Midbrain

Advances in Pharmacology, ISSN: 10543589

Rosenthal

January 1, 1997

NGF binding to p75 enhances the sensitivity of sensory and sympathetic neurons to NGF at different stages of development

Molecular and Cellular Neuroscience, ISSN: 10447431

Antony Horton; Laramee; Sean Wyatt; Shih; Winslow; Alun M. Davies

January 1, 1997

Hematologically important mutations: X-linked chronic granulomatous disease - An update

Blood Cells, Molecules, and Diseases, ISSN: 10799796

Heyworth; John T. Curnutte; Julie Rae; Noack; Andrew R. Cross

January 1, 1997

P-115. Recombinant human (rh) GHBP: Effects on GH action in the rat

Endocrinology and Metabolism, Supplement, ISSN: 1074939X

Deborah L. Mortensen; Carlsson; Winkler; Ross Clark

January 1, 1997

The Pharmaceutical Development of Insulin: Historical Perspectives and Future Directions

ACS Symposium Series, ISSN: 00976156

Henry R. Costantino; Stanley Liauw; Samir Mitragotri; Langer; Klibanov; Victoria Sluzky

January 1, 1997

Growth hormone/IGF-I and/or resistive exercise maintains myonuclear number in hindlimb unweighted muscles

Journal of Applied Physiology, ISSN: 87507587

Allen; Jon K. Linderman; Roy; Richard E. Grindeland; Mukku; Edgerton

January 1, 1997

MyD88: An adapter that recruits IRAK to the IL-1 receptor complex

Immunity, ISSN: 10747613

Holger Wesche; William J. Henzel; Wendy Shillinglaw; Shyun Li; Zhaodan Cao

January 1, 1997

The role of assay validation in specification development.

Developments in biological standardization, ISSN: 03015149

Baffi

January 1, 1997

O-015. rhIGF-I: Differential sensitivity to SQ bolus vs continuous delivery

Endocrinology and Metabolism, Supplement, ISSN: 1074939X

Nelly Mauras; Paul M. Martha Jr.; Quarmby; Haymond

January 1, 1997

Preparation and Characterization of Poly(ethylene glycol)ylated Human Growth Hormone Antagonist

ACS Symposium Series, ISSN: 00976156

Olson; Richard L. Gehant; Mukku; Kathy L. O'Connell; Brandon Tomlinson; Klara Totpal; Winkler

January 1, 1997

Specifications from a biotechnology industry perspective.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick

January 1, 1997

Csk and BatK Show Opposite Temporal Expression in the Rat CMS: Consistent with its Late Expression in Development, BatK Induces Differentiation of PC12 Cells

European Journal of Neuroscience, ISSN: 0953816X

Sophia S. Kuo

January 1, 1997

Process model and recipe structure, the conceptual design for a flexible batch plant

ISA Transactions, ISSN: 00190578

Hans Koning-Bastiaan

January 1, 1997

Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

American Journal of Physiology - Cell Physiology, ISSN: 03636143

Turner; Brian K. Rill; Susan L. Carlson; Denice K. Carnes; Rachel Kerner; Mrsny; James L. Madara

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