Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12401 - 12450 OF 15572 RESULTS

Gain-of-function Chinese hamster ovary mutants LEC18 and LEC14 each express a novel N-acetylglucosaminyltransferase activity
Journal of Biological Chemistry, ISSN: 00219258
T. Shantha Raju; Pamela Stanley
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Opposite effects of recombinant human transforming growth factor-β1 on bone regeneration in vivo: Effects of exclusion of periosteal cells by microporous membrane
Bone, ISSN: 87563282
Göran Zellin; Beck; Ross Hardwick; Linde
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Differential dependency of unmyelinated and aδ epidermal and upper dermal innervation on neurotrophins, Trk receptors, and p75(LNGFR)
Developmental Biology, ISSN: 00121606
Rice; Albers; Davis; Silos-Santiago; Wilkinson; LeMaster; Ernfors; Smeyne; Aldskogius; Phillips; Barbacid; DeChiara; Yancopoulos; Dunne; Fundin
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EGF-induced redistribution of erbB2 on breast tumor cells: Flow and image cytometric energy transfer measurements
Communications in Clinical Cytometry, ISSN: 01964763
Péter Nagy; László Bene; Margit Balázs; William C. Hyun; Steven J. Lockett; Nancy Y. Chiang; Frederick Waldman; Burt G. Feuerstein; Sándor Damjanovich; János Szöllosi
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FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
Cell, ISSN: 00928674
Weilan Ye; Kenji Shimamura; John L. R. Rubenstein; Mary Hynes; Rosenthal
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GDNF is abundant in the adult rat gut
Journal of the Autonomic Nervous System, ISSN: 01651838
Robert J. Peters; Mark A. Osinski; Hongo; Bennett; Angela J. Okragly; Haak-Frendscho; Miles L. Epstein
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Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin-like growth factor in HIV-infected patients
AIDS, ISSN: 02699370
Bach-Yen Nguyen; Mario Clerici; David J. Venzon; Sergio Bauza; William J. Murphy; Dan L. Longo; Michael Baseler; Gesundheit; Samuel Broder; Gene Shearer; Robert Yarchoan
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Signal Transduction
Scientist, ISSN: 08903670
Vishva M. Dixit
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Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
Journal of Biological Chemistry, ISSN: 00219258
Hans-Peter Gerber; Vishva M. Dixit; Napoleone Ferrara
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Water sorption behavior of lyophilized protein-sugar systems and implications for solid-state interactions
International Journal of Pharmaceutics, ISSN: 03785173
Henry R. Costantino; Curley; Sylvia Wu; Chung C. Hsu
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Solution structure of the heparin-binding domain of vascular endothelial growth factor
Structure, ISSN: 09692126
Wayne J. Fairbrother; Mark Champe; Hans W. Christinger; Keyt; Melissa A. Starovasnik
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A mutational analysis of binding interactions in an antigen-antibody protein-protein complex
Biochemistry, ISSN: 00062960
William Dall'Acqua; Ellen R. Goldman; Wenhong Lin; Connie Teng; Daisuke Tsuchiya; Hongmin Li; Xavier Ysern; Bradford C. Braden; Yili Li; Sandra J. Smith-Gill; Roy A. Mariuzza
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Binding interaction of the heregulinβ egf domain with ErbB3 and ErbB4 receptors assessed by alanine scanning mutagenesis
Journal of Biological Chemistry, ISSN: 00219258
Jennifer T. Jones; Ballinger; Paul Pisacane; Julie A. Lofgren; V. Danial Fitzpatrick; Wayne J. Fairbrother; James A. Wells; Mark X. Sliwkowski
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Selection of heregulin variants having higher affinity for the ErbB3 receptor by monovalent phage display
Journal of Biological Chemistry, ISSN: 00219258
Ballinger; Jennifer T. Jones; Julie A. Lofgren; Wayne J. Fairbrother; Robert W. Akita; Mark X. Sliwkowski; James A. Wells
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Hyperactivity of human DNase I variants: Dependence on the number of positively charged residues and concentration, length, and environment of DNA
Journal of Biological Chemistry, ISSN: 00219258
Clark Q. Pan; Lazarus
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Peroxisome degradation by microautophagy in Pichia pastoris: Identification of specific steps and morphological intermediates
Journal of Cell Biology, ISSN: 00219525
Yasuyoshi Sakai; Antonius Koller; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani
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A multicenter study of platelet recovery and utilization in patients after myeloablative therapy and hematopoietic stem cell transplantation
Blood, ISSN: 00064971
Bernstein; Auayporn P. Nademanee; Julie Vose; Guido Tricot; Fay; Robert Negrin; John DiPersio; Gabriela Rondon; Richard Champlin; Michael J. Barnett; Kenneth Cornetta; Geoffrey P. Herzig; William Vaughan; George Geils Jr.; Armand Keating; Hans Messner; Wolff; Kenneth B. Miller; Charles Linker; Mitchell S. Cairo; Hellmann; Ashby; Scott Stryker; Richard A. Nash
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A high-throughput microscale method to release N-linked oligosaccharides from glycoproteins for matrix-assisted laser desorption/ionizatiom time-of-flight mass spectrometric analysis
Glycobiology, ISSN: 09596658
Damon I. Papac; Briggs; Chin; Andrew J.S. Jones
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Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor
Journal of Biological Chemistry, ISSN: 00219258
Fuh; Bing Li; Crowley; Cunningham; James A. Wells
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Adaptive calibration scheme for quantification of nutrients and byproducts in insect cell bioreactors by near-infrared spectroscopy
Biotechnology Progress, ISSN: 87567938
Mark R. Rileys; Mark A. Arnold; David W. Murhammer; Ed L. Walls; Neslihan DelaCruz
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The peptidyl-prolyl isomerase domain of the CyP-40 cyclophilin homolog Cpr7 is not required to support growth or glucocorticoid receptor activity in Saccharomyces cerevisiae
Journal of Biological Chemistry, ISSN: 00219258
Andrea A. Duina; James A. Marsh; Richard B. Kurtz; Hui-Chen Jane Chang; Susan Lindquist; Richard F. Gaber
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Environmental control and monitoring in bulk manufacturing facilities for biological products
Pharmaceutical Technology, ISSN: 01478087
Joe Barta
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APO2 ligand: A novel lethal weapon against malignant glioma?
FEBS Letters, ISSN: 00145793
Johannes Rieger; Ulrike Naumann; Tamara Glaser; Avi Ashkenazi; Michael Weller
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Body composition of HIV/AIDS males: Effects of treatment with insulin- like growth factor (IGF-I) and growth hormone (GH)
Applied Radiation and Isotopes, ISSN: 09698043
Ellis; Lee; Pivarnik; Julie Bukar; Gesundheit
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Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
Cell, ISSN: 00928674
Scott J. Rodig; Marco A. Meraz; J. Michael White; Patricia A. Lampe; Riley; Cora D. Arthur; King; Kathleen C. Sheehan; Li Yin; Diane Pennica; Eugene M. Johnson Jr.; Schreiber
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Antigenic profiles of endothelial and hemopoietic lineages in murine intraembryonic hemogenic sites
Developmental and Comparative Immunology, ISSN: 0145305X
Juan A. Garcia-Porrero; Alexandra Manaia; Jaime Jimeno; Lasky; Françoise Dieterlen-Lièvre; Isabelle E. Godin
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Interferon gamma-1b compared with placebo in metastatic renal-cell carcinoma
New England Journal of Medicine, ISSN: 00284793
Martin E. Gleave; Mostafa Elhilali; Yves Fradet; Ian Davis; Peter Venner; Fred Saad; Laurence H. Klotz; Moore; Virginia Paton; Alex Bajamonde; David Bell; Scott Ernst; Ernest Ramsey; Joe Chin; Alvaro Morales; Heidi Martins; Corsee Sanders
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Stability of alkoxycarbonylamidine prodrugs
Pharmaceutical Research, ISSN: 07248741
Shahrokh; Eric Lee; Alan G. Olivero; Regina A. Matamores; Kirk D. Robarge; Arthur Lee; Kenneth J. Weise; Brent Blackburn; Powell
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Recognition properties of a sequence-specific DNA binding antibody
Biochemistry, ISSN: 00062960
James F. LeBlanc; Kathryn E. McLane; Paul W. H. I. Parren; Dennis R. Burton; Peter Ghazal
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Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis
Journal of Cell Science, ISSN: 00219533
Pascal G. Villa; William J. Henzel; Monique Sensenbrenner; Christopher E. Henderson; Brigitte Pettmann
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Identification of a ligand for the death-domain-containing receptor Apo3
Current Biology, ISSN: 09609822
Scot A. Marsters; James P. Sheridan; Pitti; Brush; Goddard; Avi Ashkenazi
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Cranial computed tomography interpretation in acute stroke: Physician accuracy in determining eligibility for thrombolytic therapy
JAMA - Journal of the American Medical Association, ISSN: 00987484
David L. Schriger; Mary Kalafut; Sidney Starkman; Michelle Krueger; Jeffrey L. Saver
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Characterization of V3 loop-Pseudomonas exotoxin chimeras: Candidate vaccines for human immunodeficiency virus-1
Journal of Biological Chemistry, ISSN: 00219258
David FitzGerald; Charlotte M. Fryling; Marian McKee; Vennari; Wrin; Cromwell; Daugherty; Mrsny
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Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity
Journal of Molecular Biology, ISSN: 00222836
Clackson; Ultsch; James A. Wells; De Vos
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A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production
Journal of Immunology, ISSN: 00221767
Sylvia L. F. Pender; John M. E. Fell; Steven M. Chamow; Avi Ashkenazi; Thomas T. MacDonald
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A large-scale process to produce microencapsulated proteins
Pharmaceutical Research, ISSN: 07248741
Paul Herbert; Keith Murphy; OluFunmi Johnson; Nan Dong; Warren Jaworowicz; Mark A. Tracy; Cleland; Putney
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Vascular endothelial growth factor is essential for corpus luteum angiogenesis
Nature Medicine, ISSN: 10788956
Napoleone Ferrara; Helen Chen; Terri Davis-Smyth; Hans-Peter Gerber; Thuy-Nhung Nguyen; Peers; Chisholm; Kenneth J. Hillan; Ralph H. Schwall
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Activation of caspases triggered by cytochrome c in vitro
FEBS Letters, ISSN: 00145793
Guoha Pan; Eric W. Humke; Vishva M. Dixit
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An integrated approach to proteome analysis: Identification of proteins associated with cardiac hypertrophy
Analytical Biochemistry, ISSN: 00032697
David Arnott; Kathy L. O'Connell; King; Stults
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TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination
Nature Medicine, ISSN: 10788956
Junliang Liu; Michael W. Marino; Grace H.W. Wong; Dianne Grail; Ashley Dunn; Jayaram Bettadapura; Anthony J. Slavin; Lloyd Old; Claude C.A. Bernard
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Purification and characterization of a GDP-fucose:polypeptide fucosyltransferase from Chinese hamster ovary cells
Journal of Biological Chemistry, ISSN: 00219258
Yang Wang; Spellman
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Serum thrombopoietin levels in Kawasaki disease
British Journal of Haematology, ISSN: 00071048
Nobuyuki Mlura; Masaru Terai; Meng; Takeyuki Sato; Hlroo Nlimi
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Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo
Prostate, ISSN: 02704137
Per Borgström; Mario A. Bourdon; Kenneth J. Hillan; Sriramarao; Napoleone Ferrara
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Overexpression of cardiotrophin-1 and gp130 during experimental acute Chagasic cardiomyopathy
Immunology Letters, ISSN: 01652478
Bysani Chandrasekar; Peter C. Melby; Diane Pennica; Gregory L. Freeman
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Binding and regulation of thrombopoietin to human megakaryocytes
British Journal of Haematology, ISSN: 00071048
Takeyuki Sato; Akira Fuse; Hiroo Niimi; Fielder; Hava Avraham
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Receptor-specific ligands distinguish natriuretic peptide receptors-A and -C in primate tissues
Molecular and Cellular Biochemistry, ISSN: 03008177
Sehl; Jeffrey Tom; David A. Oare; David G Lowe
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Use of reperfusion therapy for acute myocardial infarction in the United States: Data from the National Registry of Myocardial Infarction 2
Circulation, ISSN: 00097322
Hal V. Barron; Laura J. Bowlby; Timothy J. Breen; William J. Rogers; John G. Canto; Yuan Zhang; Alan J. Tiefenbrunn; W.Douglas Weaver
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Validation of a capillary isoelectric focusing method for the recombinant monoclonal antibody C2B8
Journal of Chromatography A, ISSN: 00219673
Glenn Hunt; Hotaling; Chen
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Elevated expression of KDR receptor in response to Vascular Endothelial Growth Factor (VEGF) treatment
FASEB Journal, ISSN: 08926638
Shen; David Y. Lee; Hans-Peter Gerber; Napoleone Ferrara; Keyt; Zioncheck
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CARP expression in two rat cardiac hypertrophy models
FASEB Journal, ISSN: 08926638
Michael Lew; Lesley A. Brown; Sehl; Kenneth J. Hillan; David G Lowe
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