Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12451 - 12500 OF 15572 RESULTS

Immunoliposomes containing antibodies to costimulatory molecules as adjuvants for HIV subunit vaccines
AIDS Research and Human Retroviruses, ISSN: 08892229
Bulent Ozpolat; Xiao-Mei Rao; Powell; Lawrence B. Lachman
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The disruption of heregulin, ErbB2, and ErbB3 genes leads to cardiac and neural abnormalities: Roles in development and adulthood
FASEB Journal, ISSN: 08926638
Sharon Erickson
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Overexpression of Escherichia coli oxidoreductases increases recombinant insulin-like growth factor-I accumulation
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
John C. Joly; Leung; James R. Swartz
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Computational learning reveals coiled coil-like motifs in histidine kinase linker domains
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Mona Singh; Bonnie Berger; Peter S. Kim; James M. Berger; Andrea G Cochran
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Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein
Journal of Biological Chemistry, ISSN: 00219258
Yan Wu; Spencer; Lasky
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High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the TrK receptors
Journal of Biological Chemistry, ISSN: 00219258
Urfer; Tsoulfas; O'Connell; Hongo; Wei Zhao; Presta
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Caspase-9, Bcl-X(L), and Apaf-1 form a ternary complex
Journal of Biological Chemistry, ISSN: 00219258
Pan; Karen M. O'Rourke; Vishva M. Dixit
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Ammonium ion and glucosamine dependent increases of oligosaccharide complexity in recombinant glycoproteins secreted from cultivated BHK-21 cells
Biotechnology and Bioengineering, ISSN: 00063592
Martin Gawlitzek; Ulrich Valley; Roland Wagner
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Establishment of conditionally immortalized rat utricular epithelial cell lines using a retrovirus-mediated gene transfer technique
Hearing Research, ISSN: 03785955
Zheng; Lewis; Gao
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Prebeta-1 HDL in plasma of normolipidemic individuals: Influences of plasma lipoproteins, age, and gender
Journal of Lipid Research, ISSN: 00222275
Patricia M. O'Connor; Zysow; Schoenhaus; Ishida; Kunitake; Naya-Vigne; Duchateau; Redberg; Susan J. Spencer; Mark; Mazur; Heilbron; Jaffe; Malloy; Kane
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Pharmacokinetics and pharmacodynamics of recombinant tissue-type plasminogen activator following intravenous administration in rabbits: A comparison of three dosing regimens
Biopharmaceutics and Drug Disposition, ISSN: 01422782
Stephen M. Eppler; Tauri D. Senn; Ellen Gilkerson; Modi
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The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor
Journal of Experimental Medicine, ISSN: 00221007
Spencer; Francesco Di Marco; Jeff Hooley; Sharon Pitts-Meek; Michele Bauer; Anne Ryan; Bernard Sordat; Gibbs; Michel Aguet
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Structure-function study of the extracellular domain of the human IFN- α receptor (hIFNAR1) using blocking monoclonal antibodies: The role of domains 1 and 2
Journal of Immunology, ISSN: 00221767
Lu; Anan Chuntharapai; Joanne T. Beck; Bass; Ow; De Vos; Gibbs; K.Jin Kim
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Structure-function study of the extracellular domain of the human IFN- α receptor (hIFNAR1) using blocking monoclonal antibodies: The role of domains 1 and 2
Journal of Immunology, ISSN: 00221767
Lu; Anan Chuntharapai; Joanne Beck; Bass; Ow; De Vos; Gibbs; K.Jin Kim
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A novel soluble tissue factor variant with an altered factor VIIa binding interface
Journal of Biological Chemistry, ISSN: 00219258
Geoffrey F. Lee; Robert F. Kelley
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Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stability
Journal of Biological Chemistry, ISSN: 00219258
Terri Davis-Smyth; Presta; Napoleone Ferrara
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Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase
Nature Structural Biology, ISSN: 10728368
Jane Gitschier; Moffat; Dorothea Reilly; William I. Wood; Wayne J. Fairbrother
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Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain
Nature Structural Biology, ISSN: 10728368
Mikael Akke; Jun Liu; John Cavanagh; Harold P. Erickson; Arthur G. Palmer III
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Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial
Circulation, ISSN: 00097322
Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald
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Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial
Circulation, ISSN: 00097322
Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott A. Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald
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Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: The case for paracrine amplification of angiogenesis
Circulation, ISSN: 00097322
Eric Van Belle; Bernhard Witzenbichler; Donghui Chen; Marcy Silver; Ling Chang; Ralph H. Schwall; Jeffrey M. Isner
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Disruption of a putative SH3 domain and the proline-rich motifs in the 53-kDa substrate of the insulin receptor kinase does not alter its subcellular localization or ability to serve as a substrate
Journal of Cellular Biochemistry, ISSN: 07302312
Tammie C. Yeh; Wenlu Li; Gilbert-Andre Keller; Richard A. Roth
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Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis
Pediatric Pulmonology, ISSN: 87556863
David E. Geller; Howard Eigen; Stanley B. Fiel; Clark; André P. Lamarre; Charles A. Johnson; Michael W. Konstan
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An oligopeptide transporter is expressed at high levels in the pancreatic carcinoma cell lines AsPc-1 and Capan-2
Cancer Research, ISSN: 00085472
Deborah E. Gonzalez; Kuang-Ming Y. Covitz; Wolfgang Sadée; Mrsny
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Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages
European Journal of Neuroscience, ISSN: 0953816X
Antony Horton; Perry F. Bartlett; Diane Pennica; Alun M. Davies
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Synergistic effects of Schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1)
Journal of Neuroscience, ISSN: 02706474
Vilma Arce; Richard A. Pollock; Jean-Marc Philippe; Diane Pennica; Christopher E. Henderson; Odile Delapeyrière
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An induced proximity model for caspase-8 activation
Journal of Biological Chemistry, ISSN: 00219258
Marta Muzio; Brent R. Stockwell; Henning R. Stennicke; Guy S. Salvesen; Vishva M. Dixit
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Probing the structural basis of the catalytic activity of HIV-1 PR through total chemical protein synthesis
Journal of Molecular Structure: THEOCHEM, ISSN: 01661280
Maria Miller; Baca; J.K. Mohana Rao; Stephen B. H. Kent
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Calcium-dependent Ret activation by GDNF and neurturin
Oncogene, ISSN: 09509232
Chika Nozaki; Naoya Asai; Hideki Murakami; Toshihide Iwashita; Yosuke Iwata; Keizo Horibe; Robert D. Klein; Rosenthal; Masahide Takahashi
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Adenovector-mediated expression of human thrombopoietin cDNA in immune- compromised mice: Insights into the pathophysiology of osteomyelofibrosis
Journal of Immunology, ISSN: 00221767
Beat M. Frey; Shahin Rafii; Michael Teterson; Dan L. Eaton; Crystal; Malcolm A.S. Moore
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Photoaffinity labeling by 4-thiodideoxyuridine triphosphate of the HIV- 1 reverse transcriptase active site during synthesis. Sequence of the unique labeled hexapeptide
Journal of Biological Chemistry, ISSN: 00219258
Shanhua Lin; William J. Henzel; Sunil Nayak; Don Dennis
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Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein
Journal of Biological Chemistry, ISSN: 00219258
Dowbenko; Spencer; Quan; Lasky
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Identification of an inhibin receptor in gonadal tumors from inhibin α- subunit knockout mice
Journal of Biological Chemistry, ISSN: 00219258
Lawrence B. Draper; Matzuk; Veronica J. Roberts; Edward T. Cox; Jeffrey Weiss; Mather; Woodruff
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Development and validation of the migraine-specific quality of life questionnaire
Headache, ISSN: 00178748
Priti Jhingran; Jane T. Osterhaus; David W. Miller; Jeffrey T. Lee; Leonard Kirchdoerfer
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A role for FADD in T cell activation and development
Immunity, ISSN: 10747613
Craig M. Walsh; Ben G. Wen; Arul M. Chinnaiyan; Karen M. O'Rourke; Vishva M. Dixit; Stephen M. Hedrick
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Increased physical activity and the growth hormone-IGF-I axis in adolescent males
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN: 03636119
Alon Eliakim; Jo Anne Brasel; Subburaman Mohan; Wai Lee T. Wong; Dan M. Cooper
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Genetic approaches to the detection of contaminants in Escherichia coli fermentations
Biotechnology Progress, ISSN: 87567938
James R. Swartz; Nancy McFarland
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A data model for clinical study status reports
Drug Information Journal, ISSN: 00928615
David H. Christiansen; Sundin
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Local delivery of vascular endothelial growth factor via PLGA depots for treatment of vascular disease
Proceedings of the Controlled Release Society, ISSN: 10220178
Ann Park; Duenas; Thomas W. Patapoff; Cleland
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Pharmacokinetics, pharmacodynamics and tolerability of a potent, non-peptidic, GP IIb/IIIa receptor antagonist following multiple oral administrations of a prodrug form
Thrombosis and Haemostasis, ISSN: 03406245
Refino; Modi; Sherron L. Bullens; Cheryl Pater; Michael T. Lipari; Kirk D. Robarge; Brent Blackburn; Beresini; Thomas Weller; Beat Steiner; Bunting
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Development of stable formulations for PLGA/PLA microsphere vaccines
Research in Immunology, ISSN: 09232494
Cleland
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Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells
Development (Cambridge), ISSN: 09501991
Mengqing Xiang; Gao; Tama Hasson; Joyce J. Shin
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Stabilization of nerve growth factor during microencapsulation and release from microspheres
Proceedings of the Controlled Release Society, ISSN: 10220178
Lam; Duenas; Cleland
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Chromatography in biotechnology: A user's perspective
LC-GC Europe, ISSN: 14716577
John Frenz
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Integrins α(v)β3 and α5β1 mediate attachment of lyme disease spirochetes to human cells
Infection and Immunity, ISSN: 00199567
Jenifer Coburn; Loranne Magoun; Bodary; John M. Leong
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Calcium-phosphate mediated DNA transfer into HEK-293 cells in suspension: Control of physicochemical parameters allows transfection in stirred media: Transfection and protein expression in mammalian cells
Cytotechnology, ISSN: 09209069
Martin Jordan; Christiane Köhne; Florian M. Wurm
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Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain
Molecular and Cellular Biology, ISSN: 02707306
Alex H. Swirnoff; Elizabeth D. Apel; John Svaren; Bradley R. Sevetson; Drazen B. Zimonjic; Nicholas C. Popescu; Jeffrey Milbrandt
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Solvent evaporation processes for the production of controlled release biodegradable microsphere formulations for therapeutics and vaccines
Biotechnology Progress, ISSN: 87567938
Cleland
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Lymphocyte granule-mediated apoptosis: Matters of viral mimicry and deadly proteases
Immunology Today, ISSN: 01675699
Christopher J. Froelich; Vishva M. Dixit; Xiaohe Yang
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Effects of cardiotrophin-1 on haemodynamics and cardiac function in conscious rats
Cytokine, ISSN: 10434666
Hongkui Jin; Renhui Yang; Ko Annie; Diane Pennica; William I. Wood; Nicholas F. Paoni
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