Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12451 - 12500 OF 15217 RESULTS

January 1, 1997

Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin

Blood, ISSN: 00064971

Bunting; Ramon Widmer; Michael T. Lipari; Linda Rangell; Hope Steinmetz; Karen Carver-Moore; Mark Moore; Gilbert-Andre Keller; Frederic J. De Sauvage

January 1, 1997

Stimulating effect of both human recombinant inhibin A and activin A on immature porcine Leydig cell functions in vitro

Endocrinology, ISSN: 00137227

Hervé Lejeune; Franck Chuzel; Pascale Sanchez; Philippe Durand; Mather; José M. Saez

January 1, 1997

Analysis of rat vestibular hair cell development and regeneration using calretinin as an early marker

Journal of Neuroscience, ISSN: 02706474

Zheng; Gao

January 1, 1997

Mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Its binding motif for α4β7 and role in experimental colitis

Immunologic Research, ISSN: 0257277X

Sherman Fong; Susan Jones; Renz; Chiu; Anne Ryan; Presta; Jackson

January 1, 1997

Antioxidants for prevention of methionine oxidation in recombinant monoclonal antibody HER2

Journal of Pharmaceutical Sciences, ISSN: 00223549

Lam; Yang; Cleland

January 1, 1997

Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein

Journal of Virology, ISSN: 0022538X

Romke Bron; Klasse; David Wilkinson; Clapham; Annegret Pelchen-Matthews; Christine A. Power; Timothy N. C. Wells; Jin Kim; Stephen C. Peiper; James A. Hoxie; Mark Marsh

January 1, 1997

Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase

Stroke, ISSN: 00392499

Walder; Green; Darbonne; Joanne Mathias; Julie Rae; Mary C. Dinauer; John T. Curnutte; G. Roger Thomas

January 1, 1997

Receptors for the chemoattractants C5a and IL-8 are clustered on the surface of human neutrophils

Journal of Histochemistry and Cytochemistry, ISSN: 00221554

Gary D. Gray; Sharon R. Hasslen; Julia A. Ember; David F. Carney; Michael J. Herron; Stanley L. Erlandsen; Robert D. Nelson

January 1, 1997

γ-heregulin: A novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175

Oncogene, ISSN: 09509232

Gabriele Schaefer; V. Danial Fitzpatrick; Mark X. Sliwkowski

January 1, 1997

The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 Å resolution: Multiple copy flexibility and receptor binding

Structure, ISSN: 09692126

Yves A. Muller; Hans W. Christinger; Keyt; De Vos

January 1, 1997

Murine endothelial cells support fetal liver erythropoiesis and myelopoiesis via distinct interactions

British Journal of Haematology, ISSN: 00071048

Osamu Ohneda; Victoria L. Bautch

January 1, 1997

Disruption of a single allele of the nerve growth factor gene results in atrophy of basal forebrain cholinergic neurons and memory deficits

Journal of Neuroscience, ISSN: 02706474

Grace Chan; Merry Nishimura; Armanini; Crowley; Spencer; Phillips

January 1, 1997

Lindane, an inhibitor of gap junction formation, abolishes oocyte directed follicle organizing activity in vitro

Endocrinology, ISSN: 00137227

Li; Mather

January 1, 1997

Growth hormone secretagogues stimulate the hypothalamic-pituitary- adrenal axis and are diabetogenic in the Zucker diabetic fatty rat

Endocrinology, ISSN: 00137227

Ross Clark; Thomas; Deborah L. Mortensen; Wesley B. Won; Yan Hui Ma; Elizabeth Tomlinson; Fairhall; Icaf Robinson

January 1, 1997

Growth hormone and insulin-like growth factor 1: New endocrine therapies in cardiology?

Trends in Cardiovascular Medicine, ISSN: 10501738

Ross Clark

January 1, 1997

IFN-γ inducibility of class II transactivator is specifically lacking in human tumour lines: Relevance to retinoblastoma protein rescue of IFN-γ inducibility of the HLA class II genes

Immunology and Cell Biology, ISSN: 08189641

Yanmei Lu; Michael E. Tschickardt; Brian J. Schmidt; George Blanck

January 1, 1997

Apoptosis: A mechanism contributing to remodeling of skeletal muscle in response to hindlimb unweighting

American Journal of Physiology - Cell Physiology, ISSN: 03636143

Allen; Jon K. Linderman; Roy; Allison J. Bigbee; Richard E. Grindeland; Mukku; Edgerton

January 1, 1997

1H, 13C, and 15N backbone assignment and secondary structure of the receptor-binding domain of vascular endothelial growth factor

Protein Science, ISSN: 09618368

Wayne J. Fairbrother; Mark Champe; Hans W. Christinger; Keyt; Melissa A. Starovasnik

January 1, 1997

A new method for bronchial-provocation testing in asthmatic subjects using a dry powder of mannitol

American Journal of Respiratory and Critical Care Medicine, ISSN: 1073449X

Anderson; John Brannan; Spring; Spalding; Rodwell; Chan; Gonda; Andrew J. Walsh; Clark

January 1, 1997

Rb interacts with TAF(II)250/TFIID through multiple domains

Oncogene, ISSN: 09509232

Zhaohui Shao; Jennifer L. Siegert; Siegfried Ruppert; Paul D. Robbins

January 1, 1997

A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: Advantages and limitations of the Caco-2 model

Critical Reviews in Therapeutic Drug Carrier Systems, ISSN: 07434863

Delie; Rubas

January 1, 1997

Human pregnancy serum contains at least two distinct proteolytic activities with the ability to degrade insulin-like growth factor binding protein-3

Endocrinology, ISSN: 00137227

Peter Bang; Fielder

January 1, 1997

Lerk2 (ephrin-b1) is a collapsing factor for a subset of cortical growth cones and acts by a mechanism different from AL-1 (ephrin-a5)

Molecular and Cellular Neuroscience, ISSN: 10447431

Leonie Meima; Paul Moran; William Matthews; Caras

January 1, 1997

Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid β-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): Engineering of inhibitors with altered specificities

Protein Science, ISSN: 09618368

Axel J. Scheidig; Thomas R. Hynes; Laura A. Pelletier; James A. Wells; Anthony A. Kossiakoff

January 1, 1997

Regulation of interleukin 6 expression by cardiotrophin 1

Cytokine, ISSN: 10434666

Olivier Robledo; Sylvie Chevalier; Josy Froger; Annick Barthelaix-Pouplard; Diane Pennica; Hugues Gascan

January 1, 1997

Neurotrophins and time: Different roles for TrkB signaling in hippocampal long-term potentiation

Neuron, ISSN: 08966273

Hyejin Kang; Andy A. Welcher; David L. Shelton; Erin M. Schuman

January 1, 1997

Dissociation of antithrombotic effect and bleeding time prolongation in rabbits by inhibiting tissue factor function

Thrombosis and Haemostasis, ISSN: 03406245

Jacques Himber; Daniel Kirchhofer; Markus A. Riederer; Thomas B. Tschopp; Beat Steiner; Roux

January 1, 1997

Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation

Endocrinology, ISSN: 00137227

Valérie Chesneau; Rachel K. Perlman; Wenlu Li; Gilbert-Andre Keller; Marsha Rich Rosner

January 1, 1997

Direct demonstration of MuSK involvement in acetylcholine receptor clustering through identification of agonist ScFv

Nature Biotechnology, ISSN: 15461696 10870156

Xie; Jean Q. Yuan; Adams; Austin L. Gurney

January 1, 1997

Use of an anti-IgE humanized monoclonal antibody in ragweed-induced allergic rhinitis

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Thomas B. Casale; I. Leonard Bernstein; William W. Busse; Craig LaForce; David G. Tinkelman; Randall R. Stoltz; Robert J. Dockhorn; Reimann; John Q. Su; Robert B. Fick Jr.; Daniel C. Adelman

January 1, 1997

Therapeutic potential of anti-IgE antibodies

Current Opinion in Immunology, ISSN: 09527915

Christoph Heusser; Paula Jardieu

January 1, 1997

Genetic and Immunologic characterization of viruses infecting MN- rgp120-vaccinated volunteers

Journal of Infectious Diseases, ISSN: 00221899

Berman; Gray; Wrin; Vennari; Eastman; Nakamura; Francis; Geoffrey Gorse; David Schwartz

January 1, 1997

Endogenous NGF and CNTF levels in human peripheral nerve injury

NeuroReport, ISSN: 09594965

Anand; Giorgio Terenghi; Birch; Wellmer; Jesse M. Cedarbaum; Lindsay; Williams-Chestnut; Sinicropi

January 1, 1997

Nitric oxide reverses aspirin antagonism of t-PA thrombolysis in a rabbit model of thromboembolic stroke

Experimental Neurology, ISSN: 00144886

Martin M. Bednar; Cordell E. Gross; Diantha B. Howard; Sheila R. Russell; Roger G. Thomas

January 1, 1997

Factors affecting the in vitro release of recombinant human interferon- γ (rhIFN-γ) from PLGA microspheres

Journal of Pharmaceutical Sciences, ISSN: 00223549

Yang; Cleland

January 1, 1997

Minimized proteins

Current Opinion in Structural Biology, ISSN: 0959440X

Cunningham; James A. Wells

January 1, 1997

Engineering antibodies for imaging and therapy

Current Opinion in Biotechnology, ISSN: 09581669

Paul J. Carter; A. Margaret Merchant

January 1, 1997

HNMP-1: A novel hematopoietic and neural membrane protein differentially regulated in neural development and injury

Journal of Neuroscience, ISSN: 02706474

Laurel M. Bolin; Tom McNeil; Linda A. Lucian; Devaux; Karin Franz-Bacon; Daniel M. Gorman; Sandra Zurawski; Richard Murray; Terrill McClanahan

January 1, 1997

Patient-perceived severity of irritable bowel syndrome in relation to symptoms, health resource utilization and quality of life

Alimentary Pharmacology and Therapeutics, ISSN: 02692813

Hahn; Leonard Kirchdoerfer; Fullerton; Mayer

January 1, 1997

Is inadequate thrombopoietin production a major cause of thrombocytopenia in cirrhosis of the liver

Journal of Hepatology, ISSN: 01688278

Markus Peck-Radosavljevic; Johannes Zacherl; Meng; Johann Pidlich; Emanuel Lipinski; Friedrich Längle; Rudolf Steininger; Ferdinand Mühlbacher; Alfred Gangl

January 1, 1997

Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria

European Journal of Immunology, ISSN: 00142980

Rudolf Lucas; Pierre Juillard; Els Decoster; Mireille Redard; Danielle Burger; Yves Donati; Christine Giroud; Christine Monso-Hinard; Toon De Kesel; Wim A. Buurman; Mark Moore; Jean-Michel Dayer; Walter Fiers; Horst Bluethmann; Georges E. Grau

January 1, 1997

Activins, inhibins, and follistatins: Further thoughts on a growing family of regulators

Proceedings of the Society for Experimental Biology and Medicine, ISSN: 00379727

Mather; Alison Moore; Li

January 1, 1997

Blockade of endogenous ligands of TrkB inhibits formation of ocular dominance columns

Neuron, ISSN: 08966273

Robert J. Cabelli; David L. Shelton; Rosalind A. Segal; Carla J. Shatz

January 1, 1997

Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1

Neuron, ISSN: 08966273

Mary Hynes; Donna Stone; Mary Dowd; Sharon Pitts-Meek; Goddard; Austin L. Gurney; Rosenthal

January 1, 1997

Salt-loading induces decreased POMC mRNA levels, increased α-MSH immunoreactivity, and sustained elevated Fos expression in rat pituitary intermediate lobe melanotropes

Annals of the New York Academy of Sciences, ISSN: 00778923

Sharma; Kelly E. Hagler; Noel Dybdal; Chronwall

January 1, 1997

Protein denaturation by combined effect of shear and air-liquid interface

Biotechnology and Bioengineering, ISSN: 00063592

Maa; Chung C. Hsu

January 1, 1997

The effect of operating and formulation variables on the morphology of spray-dried protein particles

Pharmaceutical Development and Technology, ISSN: 10837450

Maa; Henry R. Costantino; Phuong-Anh Nguyen; Chung C. Hsu

January 1, 1997

Identification of Gas6 as a ligand for Mer, a neural cell adhesion molecule related receptor tyrosine kinase implicated in cellular transformation

Oncogene, ISSN: 09509232

Jian Chen; Kendall Carey; Godowski

January 1, 1997

Optimization of growth, viability, and specific productivity for expression of recombinant proteins in mammalian cells.

Methods in Molecular Biology, ISSN: 10643745

Mather; Alison Moore; Shawley

January 1, 1997

Statistical modeling of dose-response relationships in clinical trials - A case study

Journal of Biopharmaceutical Statistics, ISSN: 10543406

Holmgren; Koch

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