Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12501 - 12550 OF 15217 RESULTS

January 1, 1997

A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae

Molecular and Cellular Biology, ISSN: 02707306

A. Margaret Merchant; Yasuo Kawasaki; Yanru Chen; Ming Lei; Bik K. Tye

January 1, 1997

Solid-state stability of human insulin II. Effect of water on reactive intermediate partitioning in lyophiles from pH 2-5 solutions: Stabilization against covalent dimer formation

Journal of Pharmaceutical Sciences, ISSN: 00223549

Robert G. Strickley; Bradley D. Anderson

January 1, 1997

Hepatocyte growth factor stimulates the differentiation of human tracheal epithelia in vitro

American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN: 10400605

Shen; Ralph J. Panos; Kim Hansen-Guzmán; Widdicombe; Mrsny

January 1, 1997

Augmentation of Blood Platelet Levels by Intratracheal Administration of an Adenovirus Vector Encoding Human Thrombopoietin cDNA

Nature Biotechnology, ISSN: 15461696 10870156

Salvatore J. Cannizzo; Beat M. Frey; Shahin Raffi; Malcolm A.S. Moore; Dan L. Eaton; Motoyoshi Suzuki; Ravi Singh; Charles A. Mack; Crystal

January 1, 1997

The somatogenic hormones and insulin-like growth factor-1: Stimulators of lymphopoiesis and immune function

Endocrine Reviews, ISSN: 0163769X

Ross Clark

January 1, 1997

Expression of the high-affinity immunoglobulin e receptor alpha-subunit in human blood eosinophilse

International Archives of Allergy and Immunology, ISSN: 14230097 10182438

Torbjørn Bjerke; Lars K. Poulsen; Kim Zionchek; Lars P. Nielsen; Jarema Kochan; Paula Jardieu

January 1, 1997

Remodeling domain interfaces to enhance heterodimer formation

Protein Science, ISSN: 09618368

Zhu; Presta; Gerardo Zapata; Paul J. Carter

January 1, 1997

Chromosomal assignment of six muscle-specific genes in cattle

Animal Genetics, ISSN: 02689146

Anne Ryan; Schelling; Womack; Daniel S. Gallagher

January 1, 1997

Tear hepatocyte growth factor (HGF) availability increases markedly after excimer laser surface ablation

Experimental Eye Research, ISSN: 00144835

Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Marco Helena; Qianwa Liang; Wilson

January 1, 1997

rhIGF-I administration in humans: Differential metabolic effects of bolus vs. continuous subcutaneous delivery

American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849

Nelly Mauras; Paul M. Martha Jr.; Quarmby; Haymond

January 1, 1997

Immunoadhesins as research tools and therapeutic agents

Current Opinion in Immunology, ISSN: 09527915

Avi Ashkenazi; Steven M. Chamow

January 1, 1997

Preparation of excipient-free recombinant human tissue-type plasminogen activator by lyophilization from ammonium bicarbonate solution: An investigation of the two-stage sublimation phenomenon

Journal of Pharmaceutical Sciences, ISSN: 00223549

David E. Overcashier; Brooks; Henry R. Costantino; Chung C. Hsu

January 1, 1997

A mechanism for toxin insertion into membranes is suggested by the crystal structure of the channel-forming domain of colicin E1

Structure, ISSN: 09692126

Patricia A. Elkins; Amy Bunker; William A. Cramer; Cynthia V. Stauffacher

January 1, 1997

High transdominant RevM10 protein levels are required to inhibit HIV-1 replication in cell lines and primary T cells: Implication for gene therapy of AIDS

Gene Therapy, ISSN: 09697128

Plavec; Agarwal; Ho; Pineda; Auten; Baker; Matsuzaki; Escaich; Bonyhadi; Böhnlein

January 1, 1997

Elevated corticosterone is not required for the rapid induction of neuropeptide Y gene expression by an overnight fast

Endocrinology, ISSN: 00137227

E. Simon Hanson; Nancy Levin; Mary F. Dallman

January 1, 1997

Pregnancies in a patient with congenital absence of prothrombin activity: Case report

American Journal of Perinatology, ISSN: 07351631

Val A. Catanzarite; William F. Novotny; Larry M. Cousins; Jack M. Schneider

January 1, 1997

Il-8 single-chain homodimers and heterodimers: Interactions with the chemokine receptors CXCR1, CXCR2, and DARC

Protein Science, ISSN: 09618368

Leong; Henry B. Lowman; Jun Liu; Steven J. Shire; Laura DeForge; Beth Gillece-Castro; Robert S. McDowell; Hébert

January 1, 1997

Monomeric variants of IL-8: Effects of side chain substitutions and solution conditions upon dimer formation

Protein Science, ISSN: 09618368

Henry B. Lowman; Wayne J. Fairbrother; Paul H. Slagle; Rhona C. Kabakoff; Jun Liu; Steven J. Shire; Hébert

January 1, 1997

Dual hormonal replacement with insulin and recombinant human insulin- like growth factor I in IDDM: Effects on glycemic control, IGF-I levels, and safety profile

Diabetes Care, ISSN: 01495992

Teresa Quattrin; Kathryn Thrailkill; Lester Baker; Jean Litton; Karen Dwigun; Melissa Rearson; Mary Poppenheimer; Giltinan; Gesundheit; Paul M. Martha Jr.

January 1, 1997

Identification of the binding site in intercellular adhesion molecule 1 for its receptor, leukocyte function-associated antigen 1

Molecular Biology of the Cell, ISSN: 10591524

Karen L. Fisher; Lu; Riddle; K.Jin Kim; Presta; Bodary

January 1, 1997

Effect of primary emulsions on microsphere size and protein-loading in the double emulsion process

Journal of Microencapsulation, ISSN: 02652048

Maa; Chung C. Hsu

January 1, 1997

The biology of vascular endothelial growth factor

Endocrine Reviews, ISSN: 0163769X

Napoleone Ferrara; Terri Davis-Smyth

January 1, 1997

Adult height in growth hormone (GH)-deficient children treated with biosynthetic GH

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Sandra L. Blethen; Joyce Baptista; Joyce Kuntze; Foley; LaFranchi; Ann J. Johanson

January 1, 1997

TNK-tissue plasminogen activator in acute myocardial infarction: Results of the thrombolysis in myocardial infarction (TIMI) 10a dose-ranging trial

Circulation, ISSN: 00097322

Christopher P. Cannon; Carolyn H. McCabe; C.Michael Gibson; Magdi Ghali; Rafael F. Sequeira; George McKendall; Judy Breed; Modi; Fox; Russell P. Tracy; Ted W. Love; Eugene Braunwald

January 1, 1997

Analysis of protein structure in intact cells: Crosslinking in vivo between introduced cysteines in the transmembrane domain of a bacterial chemoreceptor

Protein Science, ISSN: 09618368

Andrew G. Hughson; Geoffrey F. Lee; Gerald L. Hazelbauer

January 1, 1997

Intradermal recombinant human nerve growth factor induces pressure allodynia and lowered heat-pain threshold in humans

Neurology, ISSN: 00283878

Dyck; Peroutka; Cynthia A. Rask; Burton; Baker; Lehman; Gillen; Hokanson; O'Brien

January 1, 1997

Cloning and characterization of a human leptin receptor using a biologically active leptin immunoadhesin

Journal of Molecular Endocrinology, ISSN: 09525041

Shiuh-Ming Luoh; Di Marco; Nancy Levin; Armanini; Xie; Nelson; Bennett; Mickey P. Williams; Steven A. Spencer; Austin L. Gurney; Frederic J. De Sauvage

January 1, 1997

Consistency of maximum likelihood estimators in general random effects models for binary data

Annals of Statistics, ISSN: 00905364

Steven M. Butler; Thomas A. Louis

January 1, 1997

Growth cone form is behavior-specific and, consequently, position- specific along the retinal axon pathway

Journal of Neuroscience, ISSN: 02706474

Carol A. Mason; Li-Chong Wang

January 1, 1997

Adult mammalian sensory and motor neurons: Roles of endogenous neurotrophins and rescue by exogenous neurotrophins after axotomy

Journal of Neuroscience, ISSN: 02706474

John B. Munson; David L. Shelton; McMahon

January 1, 1997

Induction of cell proliferation by fibroblast and insulin-like growth factors in pure rat inner ear epithelial cell cultures

Journal of Neuroscience, ISSN: 02706474

Zheng; Christian Helbig; Gao

January 1, 1997

The role of cultured Schwann cell grafts in the repair of gaps within the peripheral nervous system of primates

Experimental Neurology, ISSN: 00144886

Allan D. O. Levi; Volker K. H. Sonntag; Curtis Dickman; Mather; Li; Steve C. Cordoba; Bill Bichard; Michael Berens

January 1, 1997

Principles and practice of immunodetection in FIA and HPLC

LC-GC Europe, ISSN: 14716577

Krull; Cho; Strong; Vanderlaan

January 1, 1997

Single administration malaria transmission-blocking PLGA vaccine

Proceedings of the Controlled Release Society, ISSN: 10220178

Cleland; Duenas; Kaslow

January 1, 1997

Local controlled delivery of vascular endothelial growth factor provides neovascularization

Proceedings of the Controlled Release Society, ISSN: 10220178

Cleland; Duenas; Jeanne Kahn; Ann Park; Daugherty; R. Andrew Cuthbertson

January 1, 1997

Sustained release of recombinant human insulin-like growth FACTOR-I for treatment of diabetes

Proceedings of the Controlled Release Society, ISSN: 10220178

Lam; Duenas; Gong; Nguyen; Yang; Yeung; Oeswein; Cleland

January 1, 1997

Clinical trial safety surveillance in the new regulatory and harmonization environment: Lessons learned from the 'fialuridine crisis'

Drug Information Journal, ISSN: 00928615

Nickas

January 1, 1997

Carbohydrate-directed cross-linking reagents

Biotechnology Advances, ISSN: 07349750

Avi Ashkenazi; Steven M. Chamow; Timothy P. Kogan

January 1, 1997

Controlled delivery of nerve growth factor for local treatment of neuronal diseases

Proceedings of the Controlled Release Society, ISSN: 10220178

Cleland; Duenas

January 1, 1997

Method and means for microbial polypeptide expression

Biotechnology Advances, ISSN: 07349750

Itakura Keiichi; Arthur D. Riggs

January 1, 1997

Effects of temperature shift on cell cycle, apoptosis and nucleotide pools in CHO cell batch cultues

Cytotechnology, ISSN: 09209069

Alison Moore; Jennifer Mercer; George Dutina; Christopher J. Donahue; Kenneth D. Bauer; Mather; Etcheverry; Thomas Ryll

January 1, 1997

Outsourcing management in the pharmaceutical industry: The early stages at four United States companies

Drug Information Journal, ISSN: 00928615

Debbie A. Daniel; Nanette Nanjo-Jones; James Kirwin; Sue A. Stempien

January 1, 1997

Inhibition of vascular endothelial cell growth factor suppresses the in vivo growth of human prostate tumors

Urologic Oncology: Seminars and Original Investigations, ISSN: 10781439

Alexander Kirschenbaum; Jin-Ping Wang; Meiyue Ren; Jonathan D. Schiff; Stuart A. Aaronson; Michael J. Droller; Napoleone Ferrara; James F. Holland; Alice C. Levine

January 1, 1997

Microencapsulation of recombinant humanized monoclonal antibody for local delivery

Proceedings of the Controlled Release Society, ISSN: 10220178

Lam; Duenas; Cleland

January 1, 1997

Method of formulating IGF-I with growth hormone

Biotechnology Advances, ISSN: 07349750

Ross Clark; Yeung; Oeswein

January 1, 1997

Single-chain hepatocyte growth factor variants

Biotechnology Advances, ISSN: 07349750

Godowski; Lokker; Melanie R Mark

January 1, 1997

Method and means for microbial polypeptide expression

Biotechnology Advances, ISSN: 07349750

Itakura Keiichi; Arthur D. Riggs

January 1, 1997

A paracrine effect for neuron-derived BNDF in development of dorsal root ganglia: Stimulation of Schwann cell myelin expression by glial cells

Mechanisms of Development, ISSN: 09254773

Merav Pruginin-Bluger; David L. Shelton; Chaya Kalcheim

January 1, 1997

Insulin-like growth factor binding protein-1 induces insulin release in the rat

Endocrinology, ISSN: 00137227

Deborah L. Mortensen; Wesley B. Won; Siu; David H. Reifsnyder; Gironella; Etcheverry; Ross Clark

January 1, 1997

Vascular endothelial growth factor: basic biology and clinical implications.

EXS, ISSN: 1023294X

Napoleone Ferrara; Keyt

Join Our Team

The little things we do every day add up to big breakthroughs. Making a difference in the lives of millions starts when you make a change in yours.

Two Scientists Walk Into a Bar

Two Scientists Walk Into a Bar

Listen to our podcast, where researchers talk about their work answering the toughest questions in human biology.