Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12501 - 12550 OF 15572 RESULTS

January 1, 1998

Computer system validation: Value added activities meeting regulatory imperatives

Drug Information Journal, ISSN: 00928615

Woodrum

January 1, 1998

Substantially attenuated hemodynamic responses to Escherichia coli- derived vascular endothelial growth factor given by intravenous infusion compared with bolus injection

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565

Renhui Yang; Bunting; Annie Ko; Keyt; Modi; Zioncheck; Napoleone Ferrara; Hongkui Jin

January 1, 1998

Mucosal administration of a non-toxic Pseudomonas exotoxin-gp120 V3 loop chimera elevates gp120 specific IgG and IgA in the serum and saliva of BALB/c mice

Proceedings of the Controlled Release Society, ISSN: 10220178

Daugherty; Silva; Charlotte M. Fryling; David FitzGerald; Mrsny

January 1, 1998

Mucoadhesive microparticles for antigen delivery

Proceedings of the Controlled Release Society, ISSN: 10220178

Claudia Witschi; Mrsny

January 1, 1998

AtDB, the Arabidopsis thaliana Database, and graphical-web-display of progress by the Arabidopsis genome initiative

Nucleic Acids Research, ISSN: 03051048

David J. Flanders; Shuai Weng; Fabien X. Petel; J. Michael Cherry

January 1, 1998

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear

Mechanisms of Development, ISSN: 09254773

Lewis; Gretchen D. Frantz; David Carpenter; Frederic J. De Sauvage; Gao

January 1, 1998

Fourier-transform infrared spectroscopic investigation of the secondary structure of aqueous and dried recombinant human deoxyribonuclease I

Pharmacy and Pharmacology Communications, ISSN: 14608081

Henry R. Costantino; Bei Chen; Kai Griebenow; Chung C. Hsu; Steven J. Shire

January 1, 1998

Activating Smoothened mutations in sporadic basal-cell carcinoma

Nature, ISSN: 00280836

Jingwu Xie; Maximilien Murone; Shiuh-Ming Luoh; Anne Ryan; Qimin Gu; Chaohui Zhang; Jeannette M. Bonifas; Ching-Wan Lam; Mary Hynes; Goddard; Rosenthal; Ervin H. Epstein Jr.; Frederic J. De Sauvage

January 1, 1998

Amino acid sequence similarity of Hev b 3 to two previously reported 27- and 23-kDa latex proteins allergenic to spina bifida patients

Allergy: European Journal of Allergy and Clinical Immunology, ISSN: 01054538

Yeang; Ward; Zamri; Dennis; Light

January 1, 1998

Pharmacokinetics of a slower clearing tissue plasminogen activator variant, TNK-tPA, in patients with acute myocardial infarction

Thrombosis and Haemostasis, ISSN: 03406245

Modi; Stephen M. Eppler; Judy Breed; Christopher P. Cannon; Eugene Braunwald; Ted W. Love

January 1, 1998

Biological aspects of the intestinal epithelial barrier

Proceedings of the Controlled Release Society, ISSN: 10220178

Mrsny

January 1, 1998

Disaccharide analysis of heparin and heparan sulfate using deaminative cleavage with nitrous acid and subsequent labeling with paranitrophenyl hydrazine

Journal of Biochemistry, ISSN: 0021924X

Yutaka Kariya; Jörg Herrmann; Kiyoshi Suzuki; Takako Isomura; Masayuki Ishihara

January 1, 1998

Auto transplants for Parkinson's disease?

Neuron, ISSN: 08966273

Rosenthal

January 1, 1998

Spray-drying of air-liquid interface sensitive recombinant human growth hormone

Journal of Pharmaceutical Sciences, ISSN: 00223549

Maa; Phuong-Anh Nguyen; Selena W. Hsu

January 1, 1998

Persephin, a novel neurotrophic factor related to GDNF and neurturin

Neuron, ISSN: 08966273

Jeffrey Milbrandt; Frederic J. De Sauvage; Timothy J. Fahrner; Robert H. Baloh; Melanie L. Leitner; Malú G. Tansey; Patricia A. Lampe; Robert O. Heuckeroth; Paul T. Kotzbauer; Kelli S. Simburger; Judith P. Golden; Jamie A. Davies; Richard Vejsada; Ann C. Kato; Mary Hynes; Sherman; Merry Nishimura; Li-Chong Wang; Richard L. Vandlen; Moffat; Robert D. Klein; Kris Poulsen; Christa Gray; Alain Garces; Christopher E. Henderson; Phillips; Eugene M. Johnson Jr.

January 1, 1998

Endogenous serum thrombopoietin concentrations in patients with myelodysplastic syndromes

Leukemia, ISSN: 08876924

Heinz Zwierzina; Rollinger-Holzinger; Nuessler; Herold; Meng

January 1, 1998

Hematopoietic deficiencies in c-mpl and TPO knockout mice

Stem Cells, ISSN: 10665099

Maximilien Murone; David Carpenter; Frederic J. De Sauvage

January 1, 1998

A cell-based potency assay for insulin-like growth factor-I

Biologicals, ISSN: 10451056

Hélène Gazzano-Santoro; Chen; Mukku

January 1, 1998

Comparison of VEGF delivery techniques on collateral-dependent microvascular reactivity

Microvascular Research, ISSN: 00262862

Frank W Sellke; Motohisa Tofukuji; Roger J Laham; Jianyi Li; Mukesh D. Hariawala; Bunting; Michael Simons

January 1, 1998

Inhibin gene expression in a large cell calcifying Sertoli cell tumour and serum inhibin and activin levels

APMIS, ISSN: 09034641

Jorma Toppari; Antti Kaipia; Marko Kaleva; Matti Laato; David M. De Kretser; Lynne Krummen; Mather; Toivo T. Salmi

January 1, 1998

Inorganic polyphosphate in Escherichia coli: The phosphate regulon and the stringent response

Journal of Bacteriology, ISSN: 00219193

Narayana N. Rao; Shengjiang Liu; Arthur Kornberg

January 1, 1998

Humanization of an antibody against human protein C and calcium-dependence involving framework residues

Protein Engineering, ISSN: 02692139

Shane J. O'Connor; Meng; Alireza R. Rezaie; Presta

January 1, 1998

Maintenance of myonuclear domain size in rat soleus after overload and growth hormone/IGF-I treatment

Journal of Applied Physiology, ISSN: 87507587

McCall; Allen; Jon K. Linderman; Richard E. Grindeland; Roy; Mukku; Edgerton

January 1, 1998

Cardiotrophin-1 induces heat shock protein accumulation in cultured cardiac cells and protects them from stressful stimuli

Journal of Molecular and Cellular Cardiology, ISSN: 00222828

Anastatis Stephanou; Bhawanjit K. Brar; Heads; Knight; Marber; Diane Pennica; David S. Latchman

January 1, 1998

Short communication: Renal tubular vacuolation in animals treated with polyethylene-glycol-conjugated proteins

Toxicological Sciences, ISSN: 10966080

Alison Bendele; Jim Seely; Carl Richey; Gina Sennello; Shopp

January 1, 1998

Crystallization and preliminary X-ray analysis of a 1:1 complex between a designed monomeric interferon-gamma and its soluble receptor

Protein Science, ISSN: 09618368

Michael Randal; Anthony A. Kossiakoff

January 1, 1998

Rapid identification of comigrating gel-isolated proteins by ion trap- mass spectrometry

Electrophoresis, ISSN: 01730835

David Arnott; William J. Henzel; Stults

January 1, 1998

New branches on the neuregulin family tree

Molecular Psychiatry, ISSN: 13594184

Godowski; Zhang; Gretchen D. Frantz

January 1, 1998

Phage display of peptide libraries on protein scaffolds.

Methods in Molecular Biology, ISSN: 10643745

Henry B. Lowman

January 1, 1998

Hinge bending within the cytokine receptor superfamily revealed by the 2.4 Å crystal structure of the extracellular domain of rabbit tissue factor

Protein Science, ISSN: 09618368

Yves A. Muller; Robert F. Kelley; De Vos

January 1, 1998

For success, focus your strengths.

Nature Biotechnology, ISSN: 10870156

Levinson

January 1, 1998

Recent antibody targeting technologies - A survey of the patent literature

Journal of Drug Targeting, ISSN: 1061186X

Mrsny

January 1, 1998

Mutational analysis of human DNase I at the DNA binding interface: Implications for DNA recognition, catalysis, and metal ion dependence

Protein Science, ISSN: 09618368

Clark Q. Pan; Jana S. Ulmer; Herzka; Lazarus

January 1, 1998

Effect of excipients on the stability and structure of lyophilized recombinant human growth hormone

Journal of Pharmaceutical Sciences, ISSN: 00223549

Henry R. Costantino; Karen G. Carrasquillo; Rocio A. Cordero; Mumenthaler; Chung C. Hsu; Kai Griebenow

January 1, 1998

E. coli-based in vitro transcription/translation: In vivo-specific synthesis rates and high yields in a batch system

BioTechniques, ISSN: 07366205

Ranjan Patnaik; James R. Swartz

January 1, 1998

Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor

Cancer Investigation, ISSN: 07357907

Christine D. Pham; Timothy P.L. Roberts; Nicholas Van Bruggen; Ostap Melnyk; Jeffry Mann; Napoleone Ferrara; Robert L. Cohen; Robert C. Brasch

January 1, 1998

Treatment of idiopathic bronchiectasis with aerosolized recombinant human DNase I

Chest, ISSN: 00123692

Anne E. O'Donnell; Alan F. Barker; Jonathan S. Ilowite; Robert B. Fick Jr.

January 1, 1998

Acetogenesis does not replace ketogenesis in fasting piglets infused with hexanoate

American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849

Adams; Jack Odle

January 1, 1998

Regulation of megakaryocytopoiesis and platelet production: Lessons from animal models

Journal of Laboratory and Clinical Medicine, ISSN: 00222143

Frederic J. De Sauvage; Jean-Luc Villeval; Ramesh A. Shivdasani

January 1, 1998

P-glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: The influence of culturing conditions and drug exposure on P-gp expression levels

Journal of Pharmaceutical Sciences, ISSN: 00223549

Pascale Anderle; Eva Niederer; Rubas; Constanze Hilgendorf; Hilde Spahn-Langguth; Heidi Wunderli-Allenspach; Hans P. Merkle; Peter Langguth

January 1, 1998

X-linked chronic granulomatous disease: Mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase

American Journal of Human Genetics, ISSN: 00029297

Julie Rae; Peter E. Newburger; Mary C. Dinauer; Noack; Penelope J. Hopkins; Ryoko Kuruto; John T. Curnutte

January 1, 1998

A method of biased coin randomization, its implementation, and its validation

Drug Information Journal, ISSN: 00928615

James W. Frane

January 1, 1998

Expression analysis of the soluble and membrane-associated forms of the interleukin-1 receptor-related T1 protein in primary mast cells and fibroblasts

Hybridoma, ISSN: 0272457X

Dirk R. Moritz; Jacqueline Gheyselinck; Roman Klemenz

January 1, 1998

Disturbances of growth hormone-insulin-like growth factor axis and response to growth hormone in acidosis

American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN: 03636119

Karina Jandziszak; Carlos Suarez; Ethan Wasserman; Ross Clark; Bonnie Baker; Frances Liu; Hintz; Saenger; Luc P. Brion

January 1, 1998

GFRα1 is an essential receptor component for GDNF in the developing nervous system and kidney

Neuron, ISSN: 08966273

Cacalano; Isabel Fariñas; Li-Chong Wang; Kelly E. Hagler; Alison Forgie; Mark Moore; Armanini; Phillips; Anne Ryan; Louis F. Reichardt; Mary Hynes; Alun M. Davies; Rosenthal

January 1, 1998

Investigation on fouling mechanisms for recombinant human growth hormone sterile filtration

Journal of Pharmaceutical Sciences, ISSN: 00223549

Maa; Chung C. Hsu

January 1, 1998

Mouth and oropharyngeal deposition of pharmaceutical aerosols

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 08942684

Clark; Newman; Nancy Dasovich

January 1, 1998

Lacrimal gland growth factors and receptors: Lacrimal fibroblastic cells are a source of tear HGF

Advances in Experimental Medicine and Biology, ISSN: 00652598

Wilson; Li; Mohan; Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Tabor; Kim; Hargrave; Cuevas

January 1, 1998

Effect of long-term recombinant growth hormone therapy in children - The National Cooperative Growth Study, USA, 1985-1994

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

Allen W. Root; Stephen F. Kemp; Amy Chen Rundle; Ken Dana; Kenneth M. Attie

January 1, 1998

Antibody engineering

Current Opinion in Structural Biology, ISSN: 0959440X

William Dall'Acqua; Paul J. Carter

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