Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12601 - 12650 OF 15795 RESULTS

Blockade of both L-selectin and α4 integrins abrogates naive CD4 cell trafficking and responses in gut-associated lymphoid organs
International Immunology, ISSN: 09538178
Linda M. Bradley; Mary E. Malo; Sherman Fong; Susan L. Tonkonogy; Susan R. Watson
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Blockade of both L-selectin and α4 integrins abrogates naive CD4 cell trafficking and responses in gut-associated lymphoid organs
International Immunology, ISSN: 09538178
Linda M. Bradley; Mary E. Malo; Fong; Susan L. Tonkonogy; Susan R. Watson
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Improved potency of hyperactive and actin-resistant human DNase I variants for treatment of cystic fibrosis and systemic lupus erythematosus
Journal of Biological Chemistry, ISSN: 00219258
Clark Q. Pan; Tony H. Dodge; Baker; Prince; Sinicropi; Lazarus
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Altered spatial learning and memory in mice lacking the mGluR4 subtype of metabotropic glutamate receptor
Behavioral Neuroscience, ISSN: 07357044
Gerlai; John C. Roder; David R. Hampson
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Oligopeptide transporters as putative therapeutic targets for cancer cells
Pharmaceutical Research, ISSN: 07248741
Mrsny
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Insulin-like growth factor-1 but not growth hormone augments mammalian myocardial contractility by sensitizing the myofilament to Ca2+ through a wortmannin-sensitive pathway: Studies in rat and ferret isolated muscles
Circulation Research, ISSN: 00097330
Antonio Cittadini; Yoshiki Ishiguro; Hinrik Strömer; Matthias Spindler; Alan C. Moses; Ross Clark; Pamela Douglas; Joanne S. Ingwall; James P. Morgan
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The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease
Journal of Biological Chemistry, ISSN: 00219258
Divya Chaudhary; Karen M. O'Rourke; Arul M. Chinnaiyan; Vishva M. Dixit
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Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4
FEBS Letters, ISSN: 00145793
V. Danial Fitzpatrick; Paul Pisacane; Richard L. Vandlen; Mark X. Sliwkowski
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Susceptibility to Pneumocystis carinii in mice is dependent on simultaneous deletion of IFN-γ and type 1 and 2 TNF receptor genes
Journal of Immunology, ISSN: 00221767
Daniel G. Rudmann; Angela M. Preston; Mark Moore; James M. Beck
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Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons
Journal of Neuroscience, ISSN: 02706474
Brian A. Horger; Merry Nishimura; Armanini; Li-Chong Wang; Kris Poulsen; Carl Rosenblad; Deniz Kirik; Moffat; Laura C. Simmons; Eugene M. Johnson Jr.; Jeffrey Milbrandt; Rosenthal; Anders Bjorklund; Richard L. Vandlen; Mary Hynes; Phillips
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An efficient route to human bispecific IgG
Nature Biotechnology, ISSN: 10870156
A. Margaret Merchant; Zhu; Jean Q. Yuan; Goddard; Adams; Presta; Paul J. Carter
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Role of c-mpl in early hematopoiesis
Blood, ISSN: 00064971
Gregg Solar; William G. Kerr; Francis C. Zeigler; Darren Hess; Christopher J. Donahue; Frederic J. De Sauvage; Dan L. Eaton
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Experimental autoimmune encephalomyelitis induced with a combination of myelin basic protein and myelin oligodendrocyte glycoprotein is ameliorated by administration of a single myelin basic protein peptide
Journal of Immunology, ISSN: 00221767
Elizabeth A. Leadbetter; Cheryl R. Bourque; Devaux; Carl D. Olson; Geoffrey H. Sunshine; Shirish Hirani; Barbara P. Wallner; Dawn E. Smilek; Mary Pat Happ
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Contribution of domain interface residues to the stability of antibody C(H)3 domain homodimers
Biochemistry, ISSN: 00062960
William Dall'Acqua; Alexander L. Simon; Michael G. Mulkerrin; Paul J. Carter
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Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders
Pharmaceutical Research, ISSN: 07248741
Maa; Phuong-Anh Nguyen; Andya; Nancy Dasovich; Sweeney; Steven J. Shire; Chung C. Hsu
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Backbone dynamics of the EGF-like domain of heregulin-α
Journal of Molecular Biology, ISSN: 00222836
Wayne J. Fairbrother; Jun Liu; Paul Pisacane; Mark X. Sliwkowski; Arthur G. Palmer III
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Molecular mimics of insulin-like growth factor 1 (IGF-1) for inhibiting IGF-I: IGF-binding protein interactions
Biochemistry, ISSN: 00062960
Henry B. Lowman; Chen; Nicholas J. Skelton; Deborah L. Mortensen; Elizabeth Tomlinson; Michael D Sadick; Icaf Robinson; Ross Clark
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DNAse treatment does not improve the survival of lupus prone (NZB x NZW)F1 mice
Lupus, ISSN: 09612033
Verthelyi; Noel Dybdal; Kathleen A. Elias; Klinman
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ERICE, a novel FLICE-activatable caspase
Journal of Biological Chemistry, ISSN: 00219258
Eric W. Humke; Jian Ni; Vishva M. Dixit
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Modulations in lipid A and phospholipid biosynthesis pathways influence outer membrane protein assembly in Escherichia coli K-12
Molecular Microbiology, ISSN: 0950382X
Andrew Kloser; Mike Laird; Ming Deng; Rajeev Misra
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The treatment of metastatic renal cell carcinoma patients with recombinant human gamma interferon
Cancer Journal from Scientific American, ISSN: 10814442
Small; Geoffrey R. Weiss; Umme K. Malik; Philip J. Walther; David H. Johnson; George Wilding; Timothy Kuzel; Alex Bajamonde; Virginia Paton
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Retrovirus-mediated in vivo gene transfer in the replicating liver using recombinant hepatocyte growth factor without liver injury or partial hepatectomy
Human Gene Therapy, ISSN: 10430342
Ken-Ichiro Kosai; Finegold; Bich-Thuy Thi-Huynh; Margaret Tewson; Ching-Nan; Neil Bowles; Savio L. C. Woo; Ralph H. Schwall; Gretchen J. Darlington
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Gain-of-function Chinese hamster ovary mutants LEC18 and LEC14 each express a novel N-acetylglucosaminyltransferase activity
Journal of Biological Chemistry, ISSN: 00219258
T. Shantha Raju; Pamela Stanley
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Total chemical synthesis of bovine pancreatic trypsin inhibitor by native chemical ligation
FEBS Letters, ISSN: 00145793
Wuyuan Lu; Melissa A. Starovasnik; Stephen B. H. Kent
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EGF-induced redistribution of erbB2 on breast tumor cells: Flow and image cytometric energy transfer measurements
Communications in Clinical Cytometry, ISSN: 01964763
Péter Nagy; László Bene; Margit Balázs; William C. Hyun; Steven J. Lockett; Nancy Y. Chiang; Frederick Waldman; Burt G. Feuerstein; Sándor Damjanovich; János Szöllosi
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Differential dependency of unmyelinated and aδ epidermal and upper dermal innervation on neurotrophins, Trk receptors, and p75(LNGFR)
Developmental Biology, ISSN: 00121606
Rice; Albers; Davis; Silos-Santiago; Wilkinson; LeMaster; Ernfors; Smeyne; Aldskogius; Phillips; Barbacid; DeChiara; Yancopoulos; Dunne; Fundin
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Opposite effects of recombinant human transforming growth factor-β1 on bone regeneration in vivo: Effects of exclusion of periosteal cells by microporous membrane
Bone, ISSN: 87563282
Göran Zellin; Beck; Ross Hardwick; Linde
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FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
Cell, ISSN: 00928674
Weilan Ye; Kenji Shimamura; John L. R. Rubenstein; Mary Hynes; Rosenthal
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Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin-like growth factor in HIV-infected patients
AIDS, ISSN: 02699370
Bach-Yen Nguyen; Mario Clerici; David J. Venzon; Sergio Bauza; William J. Murphy; Dan L. Longo; Michael Baseler; Gesundheit; Samuel Broder; Gene Shearer; Robert Yarchoan
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GDNF is abundant in the adult rat gut
Journal of the Autonomic Nervous System, ISSN: 01651838
Robert J. Peters; Mark A. Osinski; Hongo; Bennett; Angela J. Okragly; Haak-Frendscho; Miles L. Epstein
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Signal Transduction
Scientist, ISSN: 08903670
Vishva M. Dixit
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Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
Journal of Biological Chemistry, ISSN: 00219258
Hans-Peter Gerber; Vishva M. Dixit; Napoleone Ferrara
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Water sorption behavior of lyophilized protein-sugar systems and implications for solid-state interactions
International Journal of Pharmaceutics, ISSN: 03785173
Henry R. Costantino; Curley; Sylvia Wu; Chung C. Hsu
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Solution structure of the heparin-binding domain of vascular endothelial growth factor
Structure, ISSN: 09692126
Wayne J. Fairbrother; Mark Champe; Hans W. Christinger; Keyt; Melissa A. Starovasnik
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A mutational analysis of binding interactions in an antigen-antibody protein-protein complex
Biochemistry, ISSN: 00062960
William Dall'Acqua; Ellen R. Goldman; Wenhong Lin; Connie Teng; Daisuke Tsuchiya; Hongmin Li; Xavier Ysern; Bradford C. Braden; Yili Li; Sandra J. Smith-Gill; Roy A. Mariuzza
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Hyperactivity of human DNase I variants: Dependence on the number of positively charged residues and concentration, length, and environment of DNA
Journal of Biological Chemistry, ISSN: 00219258
Clark Q. Pan; Lazarus
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Selection of heregulin variants having higher affinity for the ErbB3 receptor by monovalent phage display
Journal of Biological Chemistry, ISSN: 00219258
Ballinger; Jennifer T. Jones; Julie A. Lofgren; Wayne J. Fairbrother; Robert W. Akita; Mark X. Sliwkowski; James A. Wells
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Binding interaction of the heregulinβ egf domain with ErbB3 and ErbB4 receptors assessed by alanine scanning mutagenesis
Journal of Biological Chemistry, ISSN: 00219258
Jennifer T. Jones; Ballinger; Paul Pisacane; Julie A. Lofgren; V. Danial Fitzpatrick; Wayne J. Fairbrother; James A. Wells; Mark X. Sliwkowski
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Peroxisome degradation by microautophagy in Pichia pastoris: Identification of specific steps and morphological intermediates
Journal of Cell Biology, ISSN: 00219525
Yasuyoshi Sakai; Antonius Koller; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani
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A multicenter study of platelet recovery and utilization in patients after myeloablative therapy and hematopoietic stem cell transplantation
Blood, ISSN: 00064971
Bernstein; Auayporn P. Nademanee; Julie Vose; Guido Tricot; Fay; Robert Negrin; John DiPersio; Gabriela Rondon; Richard Champlin; Michael J. Barnett; Kenneth Cornetta; Geoffrey P. Herzig; William Vaughan; George Geils Jr.; Armand Keating; Hans Messner; Wolff; Kenneth B. Miller; Charles Linker; Mitchell S. Cairo; Hellmann; Ashby; Scott Stryker; Richard A. Nash
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Antigenic profiles of endothelial and hemopoietic lineages in murine intraembryonic hemogenic sites
Developmental and Comparative Immunology, ISSN: 0145305X
Juan A. Garcia-Porrero; Alexandra Manaia; Jaime Jimeno; Lasky; Françoise Dieterlen-Lièvre; Isabelle E. Godin
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Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
Cell, ISSN: 00928674
Scott J. Rodig; Marco A. Meraz; J. Michael White; Patricia A. Lampe; Riley; Cora D. Arthur; King; Kathleen C. Sheehan; Li Yin; Diane Pennica; Eugene M. Johnson Jr.; Schreiber
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Body composition of HIV/AIDS males: Effects of treatment with insulin- like growth factor (IGF-I) and growth hormone (GH)
Applied Radiation and Isotopes, ISSN: 09698043
Ellis; Lee; Pivarnik; Julie Bukar; Gesundheit
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APO2 ligand: A novel lethal weapon against malignant glioma?
FEBS Letters, ISSN: 00145793
Johannes Rieger; Ulrike Naumann; Tamara Glaser; Avi Ashkenazi; Michael Weller
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Environmental control and monitoring in bulk manufacturing facilities for biological products
Pharmaceutical Technology, ISSN: 01478087
Joe Barta
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The peptidyl-prolyl isomerase domain of the CyP-40 cyclophilin homolog Cpr7 is not required to support growth or glucocorticoid receptor activity in Saccharomyces cerevisiae
Journal of Biological Chemistry, ISSN: 00219258
Andrea A. Duina; James A. Marsh; Richard B. Kurtz; Hui-Chen Jane Chang; Susan Lindquist; Richard F. Gaber
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Adaptive calibration scheme for quantification of nutrients and byproducts in insect cell bioreactors by near-infrared spectroscopy
Biotechnology Progress, ISSN: 87567938
Mark R. Rileys; Mark A. Arnold; David W. Murhammer; Ed L. Walls; Neslihan DelaCruz
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Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor
Journal of Biological Chemistry, ISSN: 00219258
Fuh; Bing Li; Crowley; Cunningham; James A. Wells
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A high-throughput microscale method to release N-linked oligosaccharides from glycoproteins for matrix-assisted laser desorption/ionizatiom time-of-flight mass spectrometric analysis
Glycobiology, ISSN: 09596658
Damon I. Papac; Briggs; Chin; Andrew J.S. Jones
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Interferon gamma-1b compared with placebo in metastatic renal-cell carcinoma
New England Journal of Medicine, ISSN: 00284793
Martin E. Gleave; Mostafa Elhilali; Yves Fradet; Ian Davis; Peter Venner; Fred Saad; Laurence H. Klotz; Moore; Virginia Paton; Alex Bajamonde; David Bell; Scott Ernst; Ernest Ramsey; Joe Chin; Alvaro Morales; Heidi Martins; Corsee Sanders
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