Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12651 - 12700 OF 15572 RESULTS

Structural plasticity in a remodeled protein-protein interface
Science, ISSN: 00368075
Shane Atwell; Ultsch; De Vos; James A. Wells
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The use of sequential high-performance liquid chromatography and capillary zone electrophoresis to separate the glycosylated peptides from recombinant tissue plasminogen activator to a detailed level of microheterogeneity
Analytical Biochemistry, ISSN: 00032697
Shiaw-Lin Wu
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Capillary electrophoresis based immunoassays: A critical review
Electrophoresis, ISSN: 01730835
Dieter Schmalzing; Wassim Nashabeh
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The effect of inhaling a dry powder of sodium chloride on the airways of asthmatic subjects
European Respiratory Journal, ISSN: 09031936
Anderson; Spring; Moore; Rodwell; Spalding; Gonda; Chan; Andrew J. Walsh; Clark
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Potent α4β1 peptide antagonists as potential anti-inflammatory agents
Journal of Medicinal Chemistry, ISSN: 00222623
Jackson; Quan; Dean R. Artis; Thomas E. Rawson; Brent Blackburn; Martin Struble; Geraldine Fitzgerald; Kathryn S. Chan; Sheldon Mullins; Burnier; Wayne J. Fairbrother; Clark; Maureen Berisini; Henry Chui; Renz; Susan Jones; Fong
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Potent α4β1 peptide antagonists as potential anti-inflammatory agents
Journal of Medicinal Chemistry, ISSN: 00222623
Jackson; Quan; Dean R. Artis; Thomas E. Rawson; Brent Blackburn; Martin Struble; Geraldine Fitzgerald; Kathryn S. Chan; Sheldon Mullins; Burnier; Wayne J. Fairbrother; Clark; Maureen Berisini; Henry Chui; Renz; Susan Jones; Sherman Fong
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Single step method for the accurate concentration determination of polysorbate 80
Journal of Chromatography A, ISSN: 00219673
Travis H. Tani; Jamie M. R. Moore; Thomas W. Patapoff
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Hypercholesterolemia attenuates angiogenesis but does not preclude augmentation by angiogenic cytokines
Circulation, ISSN: 00097322
Eric Van Belle; Alain Rivard; Donghui Chen; Marcy Silver; Bunting; Napoleone Ferrara; James F. Symes; Christophe Bauters; Jeffrey M. Isner
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A p47-phox pseudogene carries the most common mutation causing p47- phox-deficient chronic granulomatous disease
Journal of Clinical Investigation, ISSN: 00219738
Agnes Görlach; Pauline L. Lee; Joachim Roesler; Penelope J. Hopkins; Barbara Christensen; Eric D. Green; Stephen J. Chanock; John T. Curnutte
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Formulation Development and Primary Degradation Pathways for Recombinant Human Nerve Growth Factor
Analytical Chemistry, ISSN: 00032700
Eng; Victor Ling; Jonathan A. Briggs; Karen Souza; Eleanor Canova-Davis; Powell; Linda R. De Young
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Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
Cancer Research, ISSN: 00085472
Presta; Helen Chen; Shane J. O'Connor; Chisholm; Meng; Lynne Krummen; Winkler; Napoleone Ferrara
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Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation
Histochemistry and Cell Biology, ISSN: 09486143
Heyworth; John M. Robinson; Jiabing Ding; Beverly A. Ellis; John A. Badwey
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Hemodynamic effects of intracoronary VEGF delivery: Evidence of tachyphylaxis and NO dependence of response
American Journal of Physiology - Heart and Circulatory Physiology, ISSN: 03636135
John J. Lopez; Roger J Laham; Joseph P. Carrozza; Motohisa Tofukuji; Frank W Sellke; Bunting; Michael Simons
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New advances in microsphere-based single-dose vaccines
Advanced Drug Delivery Reviews, ISSN: 0169409X
Justin Hanes; Cleland; Langer
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Estrogen and testosterone, but not a nonaromatizable androgen, direct network integration of the hypothalamo-somatotrope (growth homone)-insulin- like growth factor I axis in the human: Evidence from pubertal pathophysiology and sex-steroid hormone replacement
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Johannes D. Veldhuis; Daniel L. Metzger; Paul M. Martha Jr.; Nelly Mauras; James R. Kerrigan; Bruce Keenan; Alan D. Rogol; Steve M. Pincus
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Recombinant human growth hormone poly(lactic-co-glycolic acid) microsphere formulation development
Advanced Drug Delivery Reviews, ISSN: 0169409X
Cleland; OluFunmi Johnson; Putney; Andrew J.S. Jones
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High performance tangential flow filtration
Biotechnology and Bioengineering, ISSN: 00063592
Robert Van Reis; Shishir Gadam; Leah N. Frautschy; Scott Orlando; Elizabeth M. Goodrich; Saksena; Ralf Kuriyel; Curran M. Simpson; Steven Pearl; Andrew Zydney
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Long-term benefit of one thrombolytic over another [13] (multiple letters)
Circulation, ISSN: 00097322
Barry Grobman; Roberts
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Inhibition of virus-induced age-dependent poliomyelitis by interferon-γ
Antiviral Research, ISSN: 01663542
William A. Cafruny; Thomas R. Haven; Steven R. Lawson; Grace H.W. Wong; Raymond R.R. Rowland
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rhDNase as an example of recurrent event analysis
Statistics in Medicine, ISSN: 02776715
Terry M. Therneau; Scott Hamilton
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rhDNase as an example of recurrent event analysis
Statistics in Medicine, ISSN: 02776715
Terry M. Therneau; Scott A. Hamilton
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Characterization of UT2 cells. The induction of peroxisomal 3-hydroxy- 3-methylglutaryl-coenzyme A reductase
Journal of Biological Chemistry, ISSN: 00219258
William Harrison Engfelt; Janis E. Shackelford; Nahla Aboushadi; Nadini Jessani; Kim Masuda; Vincent G. Paton; Gilbert-Andre Keller; Skaidrite Krisans
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Insulin-like growth factor-binding protein-6 levels are elevated in serum of children with chronic renal failure: A report of the southwest pediatric nephrology study group
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
David R. Powell; Frances Liu; Bonita K. Baker; Hintz; Susan K. Durham; Eileen D. Brewer; James W. Frane; Burkhard Tonshoff; Otto Mehls; Anne-Margret Wingen; Sandra L. Watkins; Ronald J. Hogg; Lee
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Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia
Journal of Biological Chemistry, ISSN: 00219258
Hans-Peter Gerber; Fabrizio Condorelli; Jeanie Park; Napoleone Ferrara
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Role of CED-4 in the activation of CED-3 [9]
Nature, ISSN: 00280836
Arul M. Chinnaiyan; Divya Chaudhary; Karen M. O'Rourke; Eugene V. Koonin; Vishva M. Dixit
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Structural mimicry of a native protein by a minimized binding domain
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Melissa A. Starovasnik; Andrew Braisted; James A. Wells
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Phage display of a catalytic antibody to optimize affinity for transition-state analog binding
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Baca; Thomas S. Scanlan; Robert C. Stephenson; James A. Wells
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Mutations in B-type natriuretic peptide mediating receptor-A selectivity
FEBS Letters, ISSN: 00145793
Schoenfeld; Jeffrey Tom; David G Lowe
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Development of tricalcium phosphate/amylopectin paste combined with recombinant human transforming growth factor beta 1 as a bone defect filler
Journal of Biomedical Materials Research, ISSN: 00219304
Ongpipattanakul; Tue H. Nguyen; Zioncheck; Wong; Gary Osaka; Leo Deguzman; Wyne P. Lee; L. Steven Beck
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Linear scale ultrafiltration
Biotechnology and Bioengineering, ISSN: 00063592
Robert Van Reis; Elizabeth M. Goodrich; Christine L. Yson; Leah N. Frautschy; Stephen Dzengeleski; Herbert Lutz
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Development of tricalcium phosphate/amylopectin paste combined with recombinant human transforming growth factor beta 1 as a bone defect filler
Journal of Biomedical Materials Research, ISSN: 00219304
Ongpipattanakul; Tue H. Nguyen; Zioncheck; Rita Wong; Gary Osaka; Leo Deguzman; Wyne P. Lee; L. Steven Beck
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Measurement of prebeta-1 HDL in human plasma by an ultrafiltration- isotope dilution technique
Analytical Biochemistry, ISSN: 00032697
Patricia M. O'Connor; Naya-Vigne; Duchateau; Ishida; Mazur; Schoenhaus; Zysow; Malloy; Kunitake; Kane
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Solution dynamics of the 1,2,3,4,6-penta-O-acetyl-α-D-idopyranose ring
Glycoconjugate Journal, ISSN: 02820080
David A. Horita; Philip J. Hajduk; Laura Lerner
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Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Zhang; Mark X. Sliwkowski; Melanie R Mark; Gretchen D. Frantz; Robert W. Akita; Yang Sun; Kenneth J. Hillan; Crowley; Brush; Godowski
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PSTPIP: A tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase
Journal of Cell Biology, ISSN: 00219525
Spencer; Dowbenko; Jill Cheng; Wenlu Li; Brush; Suzan Utzig; Viesturs Simanis; Lasky
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High-resolution NMR structure and backbone dynamics of the Bacillus subtilis response regulator, SpoOF: Implications for phosphorylation and molecular recognition
Biochemistry, ISSN: 00062960
Victoria A. Feher; James W. Zapf; Hoch; John M. Whiteley; McIntosh; Mark Rance; Nicholas J. Skelton; Frederick W. Dahlquist; John Cavanagh
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In vitro and in vivo redox states of the Escherichia coli periplasmic oxidoreductases DsbA and DsbC
Biochemistry, ISSN: 00062960
John C. Joly; James R. Swartz
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Autoantibodies to Ribosomal P Proteins Penetrate into Live Hepatocytes and Cause Cellular Dysfunction in Culture
Journal of Immunology, ISSN: 00221767
Mirna Koscec; Koren; Marianne Wolfson-Reichlin; Robert D. Fugate; Edward Trieu; Ira N. Targoff; Morris Reichlin
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Mutational analysis of thrombopoietin for identification of receptor and neutralizing antibody sites
Journal of Biological Chemistry, ISSN: 00219258
Kenneth H. Pearce Jr.; Beverly J. Potts; Presta; Bald; Brian M. Fendly; James A. Wells
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Thrombopoietin levels in patients with cirrhosis before and after orthotopic liver transplantation
Annals of Internal Medicine, ISSN: 00034819
Thomas G. Martin III; Kenneth A. Somberg; Meng; Robert L. Cohen; Christian A. Heid; Frederic J. De Sauvage; Shuman
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Effects of culture conditions on the production and quality of monoclonal IgA
Enzyme and Microbial Technology, ISSN: 01410229
Stoll; Chappaz; Von Stockar; Ian W. Marison
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Distinct but overlapping epitopes for the interaction of a CC-chemokine with CCR1, CCR3, and CCR5
Biochemistry, ISSN: 00062960
Pakianathan; Ellen G. Kuta; Dean R. Artis; Nicholas J. Skelton; Hébert
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Both overlapping and distinct signaling pathways for somatostatin receptor subtypes SSTR1 and SSTR2 in pituitary cells
Journal of Biological Chemistry, ISSN: 00219258
Longchuan Chen; V. Danial Fitzpatrick; Richard L. Vandlen; Armen H. Tashjian Jr.
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Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
Science, ISSN: 00368075
James P. Sheridan; Scot A. Marsters; Pitti; Austin L. Gurney; Skubatch; Daryl T. Baldwin; Lakshmi Ramakrishnan; Christa Gray; Kevin Baker; William I. Wood; Goddard; Godowski; Avi Ashkenazi
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An antagonist decoy receptor and a death domain-containing receptor for TRAIL
Science, ISSN: 00368075
Pan; Jian Ni; Ying-Fei Wei; Guo-Iiang Yu; Reiner Gentz; Vishva M. Dixit
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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
Cell, ISSN: 00928674
Hua Zou; William J. Henzel; Xuesong Liu; Alexis Lutschg; Xiaodong Wang
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Development of a single-shot subunit vaccine for HIV-I: Part 4. Optimizing microencapsulation and pulsatile release of MN rgp120 from biodegradable microspheres
Journal of Controlled Release, ISSN: 01683659
Cleland; Lim; Barron; Duenas; Powell
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The phosphorylation of bovine DNase I Asn-linked oligosaccharides is dependent on specific lysine and arginine residues
Journal of Biological Chemistry, ISSN: 00219258
Atsushi Nishikawa; Walter Gregory; John Frenz; Cacia; Stuart Kornfeld
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International practice patterns by age and severity of lung disease in cystic fibrosis: Data from the Epidemiologic Registry of Cystic Fibrosis (ERCF)
Pediatric Pulmonology, ISSN: 87556863
Christian Koch; Sheila G. McKenzie; Kaplowitz; Hodson; H. Karsten Harms; Jean Navarro; Gianni Mastella
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Expression of interleukin-1β in human breast carcinoma
Cancer, ISSN: 0008543X
Liang Jin; Ren Qi Yuan; Alexander Fuchs; Yan Yao; Ansamma Joseph; Ralph H. Schwall; Stuart J. Schnitt; Anthony Guida; Harold M. Hastings; Janet Andres; Gary Turkel; Peter J. Polverini; Itzhak D. Goldberg; Eliot M. Rosen
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