Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12651 - 12700 OF 15980 RESULTS

Conformational changes in the activation loop of the insulin receptor's kinase domain
Protein Science, ISSN: 09618368
Mark Frankel; Steven M. Bishop; Ararat J. Ablooglu; Yuan-Ping Han; Ronald A. Kohanski
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Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein soulless/Phox2a
Neuron, ISSN: 08966273
Guo; Brush; Hiroki Teraoka; Goddard; Stephen W. Wilson; Mary C. Mullins; Rosenthal
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Creatine: a review of efficacy and safety.
Journal of the American Pharmaceutical Association (Washington,D.C. : 1996), ISSN: 10865802
Graham; Hatton
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Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus
Journal of Clinical Investigation, ISSN: 00219738
Ben-Gary Harvey; Philip L. Leopold; Neil R. Hackett; Tina M. Grasso; P. Mickey Williams; Ayly Ling Tucker; Robert J. Kaner; Barbara Ferris; Gonda; Sweeney; Ramachandran Ramalingam; Kovesdi; Steven Shak; Crystal
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A common mechanism for recombinant human NGF, BDNF, NT-3, and murine NGF slow unfolding
Protein Science, ISSN: 09618368
Linda R. De Young; Charles H. Schmelzer; Louis E. Burton
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Hypertension and endothelial dysfunction in apolipoprotein E knockout mice
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642
Renhui Yang; Powell-Braxton; Annie Ko Ogaoawara; Noel Dybdal; Bunting; Osamu Ohneda; Hongkui Jin
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Comparisons of the Intraocular Tissue Distribution, Pharmacokinetics, and Safety of 125I-Labeled Full-Length and Fab Antibodies in Rhesus Monkeys Following Intravitreal Administration
Toxicologic Pathology, ISSN: 01926233
Joyce Mordenti; R. Andrew Cuthbertson; Napoleone Ferrara; Karen Thomsen; Lea Berleau; Vojtech Licko; Philip C. Allen; Celia R. Valverde; Meng; David T.W. Fei; Kathleen M. Fourre; Anne Ryan
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Intraocular pharmacokinetics and safety of a humanized monoclonal antibody in rabbits after intravitreal administration of a solution or a PLGA microsphere formulation
Toxicological Sciences, ISSN: 10966080
Joyce Mordenti; Karen Thomsen; Vojtech Licko; Lea Berleau; Jeanne Kahn; R. Andrew Cuthbertson; Duenas; Anne Ryan; Cheryl A. Schofield; Terrence W. Berger; Meng; Cleland
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Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease
Liver, ISSN: 01069543
Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Sherman Fong
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Neuregulin receptor-mediated gene transfer by human epidermal growth factor receptor 2-targeted antibodies and neuregulin-1
Cancer Gene Therapy, ISSN: 09291903
Jeffrey Kern; Robert Wakita; Mark X. Sliwkowski
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Characterization of a candidate Borrella burgdorferi β3-chain integrin ligand identified using a phage display library
Molecular Microbiology, ISSN: 0950382X
Jenifer Coburn; Wambui Chege; Loranne Magoun; Bodary; John M. Leong
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RIPs: An emerging family of kinases involved in pro-inflammatory and apoptotic signaling
Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451
Vishva M. Dixit
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Anti-IgE as novel therapy for the treatment of asthma
Current Opinion in Pulmonary Medicine, ISSN: 10705287
Robert B. Fick Jr.
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Secondary reduction in the apparent diffusion coefficient of water, increase in cerebral blood volume, and delayed neuronal death after middle cerebral artery occlusion and early reperfusion in the rat
Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X
Menno Van Lookeren Campagne; Roger Thomas; Harold Thibodeaux; James T. Palmer; Simon P. Williams; David G Lowe; Nicholas Van Bruggen
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VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain
Journal of Clinical Investigation, ISSN: 00219738
Nicholas Van Bruggen; Harold Thibodeaux; James T. Palmer; Wyne P. Lee; Ling Fu; Cairns; Daniel B. Tumas; Gerlai; Simon P. Williams; Menno Van Lookeren Campagne; Napoleone Ferrara
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Heregulin enhances regenerative proliferation in postnatal rat utricular sensory epithelium after ototoxic damage
Journal of Neurocytology, ISSN: 03004864
Zheng; Gretchen D. Frantz; Lewis; Mark X. Sliwkowski; Gao
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Capillary electrophoresis sodium dodecyl sulfate nongel sieving analysis of a therapeutic recombinant monoclonal antibody: A biotechnology perspective
Analytical Chemistry, ISSN: 00032700
Glenn Hunt; Wassim Nashabeh
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Estimating effectiveness in an observational study: A case study of dornase alfa in cystic fibrosis
Journal of Pediatrics, ISSN: 00223476
Charles A. Johnson; Butler; Michael W. Konstan; Timothy J. Breen; Morgan
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Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development
Endocrinology, ISSN: 00137227
Weifeng Ruan; Powell-Braxton; John J. Kopchick; David Kleinberg
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Effects of Igf1 gene deletion on postnatal growth patterns
Endocrinology, ISSN: 00137227
Jie Wang; Jian Zhou; Powell-Braxton; Carolyn Bondy
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Selective cloning of cell surface proteins involved in organ development: Epithelial glycoprotein is involved in normal epithelial differentiation
Endocrinology, ISSN: 00137227
Jean-Philippe Stephan; Penelope E. Roberts; Bald; James Lee; Qimin Gu; Devaux; Mather
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Analytical ultracentrifugation in the pharmaceutical industry
Journal of Pharmaceutical Sciences, ISSN: 00223549
Jun Liu; Steven J. Shire
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Somatotroph and lactotroph changes in the adenohypophyses of mice with disrupted insulin-like growth factor I gene
Endocrinology, ISSN: 00137227
Lucia Stefaneanu; Powell-Braxton; Wesley B. Won; Varadaraj Chandrashekar; Andrzej Bartke
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Elastase substrate specificity tailored through substrate-assisted catalysis and phage display
Protein Engineering, ISSN: 02692139
William Dall'Acqua; Cornelia Halin; Maria L. Rodrigues; Paul J. Carter
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Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases
Brazilian Journal of Medical and Biological Research, ISSN: 1414431X 0100879X
Belizário; Steve Sherwood; Beçak
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Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease
Liver, ISSN: 01069543
Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Fong
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Role of baseline parameters in determining indirect pharmacodynamic responses
Journal of Pharmaceutical Sciences, ISSN: 00223549
Yu-Nien Sun; William J. Jusko
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Crystal structure of the complex between VEGF and a receptor-blocking peptide
Biochemistry, ISSN: 00062960
Wiesmann; Hans W. Christinger; Andrea G Cochran; Cunningham; Wayne J. Fairbrother; Christopher J. Keenan; Meng; De Vos
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Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site
Biochemistry, ISSN: 00062960
Wayne J. Fairbrother; Hans W. Christinger; Andrea G Cochran; Fuh; Christopher J. Keenan; Quan; Stephanie K. Shriver; Jeffrey Tom; James A. Wells; Cunningham
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Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer
Nature, ISSN: 00280836
Pitti; Scot A. Marsters; David Lawrence; Margaret Roy; Frank C. Kischkel; Patrick Dowd; Arthur Huang; Christopher J. Donahue; Steve Sherwood; Daryl T. Baldwin; Godowski; William I. Wood; Austin L. Gurney; Kenneth J. Hillan; Robert L. Cohen; Goddard; David Botstein; Avi Ashkenazi
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Host defense molecule polymorphisms influence the risk for immune- mediated complications in chronic granulomatous disease
Journal of Clinical Investigation, ISSN: 00219738
Charles B. Foster; Thomas Lehrnbecher; Femke Mol; Seth M. Steinberg; David J. Venzon; Thomas J. Walsh; Noack; Julie Rae; Jerry A. Winkelstein; John T. Curnutte; Stephen J. Chanock
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Crystal structure of the MATa1/MATα2 homeodomain heterodimer in complex with DNA containing an A-tract
Nucleic Acids Research, ISSN: 03051048
Thomas Li; Yisheng Jin; Andrew K. Vershon; Cynthia Wolberger
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Safety and immunogenicity of HIV recombinant envelope vaccines in HIV- infected infants and children
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, ISSN: 10779450
John S. Lambert; James McNamara; Samuel L. Katz; Terry Fenton; Minhee Kang; Thomas C. VanCott; Robert Livingston; Elizabeth Hawkins; Jack Moye Jr.; William Borkowsky; Daniel Johnson; Ram Yogev; A-M. Duliege; Francis; Anne Gershon; Diane W. Wara; Natasha L. Martin; Myron Levin; George McSherry; Gale Smith
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Compendium of excipients for parenteral formulations
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Powell; Tue H. Nguyen; Baloian
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Probing the importance of second sphere residues in an esterolytic antibody by phage display
Journal of Molecular Biology, ISSN: 00222836
Michelle R. Arkin; James A. Wells
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Triplet energy transfer through the walls of hemicarcerands: Temperature dependence and the role of internal reorganization energy
Journal of the American Chemical Society, ISSN: 00027863
Ileana Place; Angeles Farran; Deshayes; Piotrowiak
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WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Diane Pennica; Todd A. Swanson; James W. Welsh; Margaret Roy; David Lawrence; James Lee; Brush; Lisa A. Taneyhill; Bethanne Deuel; Michael Lew; Colin K. Watanabe; Robert L. Cohen; Mona F. Melhem; Gene G. Finley; Philip Quirke; Goddard; Kenneth J. Hillan; Austin L. Gurney; David Botstein; Arnold J. Levine
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Chinese hamster ovary cells with constitutively expressed sialidase antisense RNA produce recombinant DNase in batch culture with increased sialic acid
Biotechnology and Bioengineering, ISSN: 00063592
Ferrari; Jane Gunson; James A. Lofgren; Lynne Krummen; Warner
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Real-time control of purified product collection during chromatography of recombinant human insulin-like growth factor-I using an on-line assay
Journal of Chromatography A, ISSN: 00219673
Fahrner; Philip M. Lester; Gregory S. Blank; David H. Reifsnyder
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Conformations of thioamide-containing dipeptides: A computational study
Journal of the American Chemical Society, ISSN: 00027863
Dean R. Artis; Mark A. Lipton
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7 Ty Mutagenesis
Methods in Microbiology, ISSN: 05809517
David J. Garfinkel; M. Joan Curcio; Victoria Smith
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A carboxypeptidase inhibitor markedly improves the potency of tPA in-vivo
Fibrinolysis and Proteolysis, ISSN: 13690191
Refino; Schmitt; Cheryl Pater; Bunting
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Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down- regulation and tyrosine aminotransferase induction in rat liver
Journal of Pharmacokinetics and Biopharmaceutics, ISSN: 0090466X
Sun; Debra C. DuBois; Richard R. Almon; Nancy A. Pyszczynski; William J. Jusko
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Fast Edman cycles with accelerated PTH analysis
Protein Journal, ISSN: 15723887 15734943
William J. Henzel; Jake Tropea; Kishiyama; Wendy Shillinglaw; David Dupont; Steve O'Neil
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Mucosal administration of a non-toxic pseudomonas exotoxin-gpllo V3 loop chimera elevates gpllO specific IgG and IgA in the serum and saliva of balb/c mice
FASEB Journal, ISSN: 08926638
Daugherty; Suva; Charlotte M. Fryling; David FitzGerald; Mrsny
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Acetogenesis does not replace ketogenesis in fasting piglets infused with hexanoate
American Journal of Physiology, ISSN: 00029513
Adams; Jack Odle
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Development of V3-loop pseudomonas exotoxin chimeras: Candidate vaccines for human immunodeficiency virus-1
FASEB Journal, ISSN: 08926638
David FitzGerald; Charlotte M. Fryling; Marian McKee; Ann L. Danghcrty; Randall J. Mj-sny
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The specification of sympathetic neurotransmitter phenotype depends on gp130 cytokine receptor signaling
Development (Cambridge), ISSN: 09501991
Markus Geissen; Stefan Heller; Diane Pennica; Uwe Ernsberger; Hermann Rohrer
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Treatment of indolent lymphoma with fludarabine/mitoxantrone combination: A phase II trial
Hematological Oncology, ISSN: 02780232
Christos Emmanouilides; Peter Rosen; Sara Rasti; Mary Territo; Lori Kunkel
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Transfer of a protein binding epitope to a minimal designed peptide
Biopolymers - Peptide Science Section, ISSN: 00063525
Quan; Nicholas J. Skelton; Clark; Jackson; Renz; Chiu; Keating; Beresini; Sherman Fong; Dean R. Artis
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