Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12951 - 13000 OF 15217 RESULTS

Immune defence in mice lacking type I and/or type II interferon receptors
Immunological Reviews, ISSN: 01052896
Maries F. Van Den Broek; Ulrike Müller; Sui Huang; Rolf M. Zinkernagel; Michel Aguet
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Solvent isotope effects on a hydrolysis reaction catalysed by subtilisin and its N155G mutant. Failure of the proton inventory method to report hydrogen-bonding interactions in the oxyanion hole
Journal of the Chemical Society, Chemical Communications, ISSN: 00224936
Chiang; Kresge; Chang; Powell; James A. Wells
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Surface attachment of Salmonella typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils
Journal of Cell Biology, ISSN: 00219525
Beth A. McCormick; Paul Hofman; Jin Kim; Denice K. Carnes; Samuel I. Miller; James L. Madara
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Erratum: GDNF: A potent survival factor for motoneurons present in peripheral nerve and muscle (Science (1062-1064))
Science, ISSN: 00368075
Christopher E. Henderson; Phillips; Armanini; Rosenthal; Moffet; Richard L. Vandlen; Laura C. Simmons; Alun M. Davies; Vassilis E. Koliatsos
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Neurotrophin- 4/5 postpones the death of injured spinal motoneurones in newborn rats
Brain Research, ISSN: 00068993
Schmalbruch; Rosenthal
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Rapid one-step capillary isoelectric focusing method to monitor charged glycoforms of recombinant human tissue-type plasminogen activator
Journal of Chromatography A, ISSN: 00219673
Kathy Moorhouse; Carina A. Eusebio; Glenn Hunt; Chen
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Growth hormone secretagogues: Characterization, efficacy, and minimal bioactive conformation
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Robert S. McDowell; Kathleen A. Elias; Mark S. Stanley; Burdick; Burnier; Kathryn S. Chan; Wayne J. Fairbrother; R. Glenn Hammonds; Gladys S. Ingle; Neil E. Jacobsen; Deborah L. Mortensen; Thomas E. Rawson; Wesley B. Won; Ross Clark; Todd C. Somers
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Human TAFII250 interacts with RAP74: Implications for RNA polymerase II initiation
Genes and Development, ISSN: 08909369
Siegfried Ruppert; Robert Tjian
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New variant of human tissue plasminogen activator (TPA) with enhanced efficacy and lower incidence of bleeding compared with recombinant human TPA
Circulation, ISSN: 00097322
Claude R. Benedict; Refino; Keyt; Rajbabu Pakala; Nicholas F. Paoni; G. Roger Thomas; William F. Bennett
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Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Lloyd Paul Aiello; Eric A. Pierce; Eliot D. Foley; Hitoshi Takagi; Helen Chen; Riddle; Napoleone Ferrara; George L. King; Lois E. H. Smith
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Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
Circulation, ISSN: 00097322
Takayuki Asahara; Christophe Bauters; Lu P. Zheng; Satoshi Takeshita; Bunting; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner
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Mutations of the growth hormone receptor in children with idiopathic short stature
New England Journal of Medicine, ISSN: 15334406 00284793
Goddard; Covello; Shiuh-Ming Luoh; Clackson; Kenneth M. Attie; Gesundheit; Amy Chen Rundle; James A. Wells; Carlsson
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Transgenic knockouts reveal a critical requirement for pancreatic β cell glucokinase in maintaining glucose homeostasis
Cell, ISSN: 00928674
Andrew Grupe; Hultgren; Anne Ryan; Yan Hui Ma; Michele Bauer; Stewart
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Cloning of the murine homolog of the leukemia-associated PML gene
Mammalian Genome, ISSN: 09388990 14321777
Goddard; Jean Q. Yuan; Fairbairn; Dexter; Borrow; Kozak; Solomon
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Growth responses to patterned GH delivery
Endocrine, ISSN: 0969711X 15590100
Ross Clark; Deborah L. Mortensen; Carlsson; Carmignac; Icaf Robinson
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Engineering linear f(ab')2 fragments for efficient production in Escherichia coli and enhanced antiproliferative activity
Protein Engineering, Design and Selection, ISSN: 17410126
Gerardo Zapata; John B.B. Ridgway; Joyce Mordenti; Gary Osaka; Wai Lee T. Wong; Bennett; Paul J. Carter
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A new hepatocyte stimulating factor: cardiotrophin-1 (CT-1)
FEBS Letters, ISSN: 00145793
Malte Peters; Elke Roeb; Diane Pennica; Karl-Hermann Meyer zum Büschenfelde; Stefan Rose-John
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Factors influencing the time to administration of thrombolytic therapy with recombinant tissue plasminogen activator (data from the national registry of myocardial infarction)
American Journal of Cardiology, ISSN: 00029149
Charles Maynard|; W.Douglas Weaver; Costas Lambrew; Laura J. Bowlby; William J. Rogers; R. Michael Rubison; The Participants in the National Registry of Myocardial Infarction
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Inducible gene targeting in mice
Science, ISSN: 00368075
Ralf Kühn; Frieder Schwenk; Michel Aguet; Klaus Rajewsky
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Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for other glucagon-like peptides
Regulatory Peptides, ISSN: 01670115
Karin Hupe-Sodmann; Gerard Patrick McGregor; Robert L. Bridenbaugh; Rüdiger Göke; Burkhard Göke; Hubert Thole; Bodo Zimmermann; Karlheinz Voigt
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Reevaluation of the roles of protein S and gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3
Cell, ISSN: 00928674
Godowski; Melanie R Mark; Jian Chen; Michael D Sadick; Helga Raab; R. Glenn Hammonds
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Missing link in angiogenesis
Nature, ISSN: 00280836
Napoleone Ferrara
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Recombinant human growth hormone in infants and young children with chronic renal insufficiency
Pediatric Nephrology, ISSN: 0931041X 1432198X
Richard N. Fine; Kenneth M. Attie; Joyce Kuntze; Douglas F. Brown; Edward C. Kohaut
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Cytochrome b-245 of the neutrophil superoxide-generating system contains two nonidentical hemes: Potentiometric studies of a mutant form of gp91phox
Journal of Biological Chemistry, ISSN: 00219258
Andrew R. Cross; Julie Rae; John T. Curnutte
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A Comparison of neutron diffraction and molecular dynamics structures: Hydroxyl group and water molecule orientations in trypsin
Journal of Molecular Biology, ISSN: 00222836
Robert S. McDowell; Anthony A. Kossiakoff
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Allergen-induced histamine release in rat mast cells transfected with the α subunits of FcεRI
Journal of Immunological Methods, ISSN: 00221759
John Lowe; Paula Jardieu; Kimmie VanGorp; David T.W. Fei
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Growth hormone improves cardiac performance in experimental heart failure
Circulation, ISSN: 00097322
Renhui Yang; Bunting; Nancy Gillett; Ross Clark; Hongkui Jin
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Stimulation of myofibrillar protein synthesis in hindlimb suspended rats by resistance exercise and growth hormone
Life Sciences, ISSN: 00243205
Jon K. Linderman; Justen B. Whittall; Kristin L. Gosselink; Tommy J. Wang; Mukku; Frank W. Booth; Richard E. Grindeland
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Stereochemistry of the benzodiazepine based Ras farnesyltransferase inhibitors
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Thomas E. Rawson; Todd C. Somers; James C. Marsters Jr.; Dairian T. Wan; Mark E. Reynolds; Burdick
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Interferon γ signals via a high-affinity multisubunit receptor complex that contains two types of polypeptide chain
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Scot A. Marsters; Diane Pennica; Bach; Schreiber; Avi Ashkenazi
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Processing of C-terminal lysine and arginine residues of proteins isolated from mammalian cell culture
Journal of Chromatography A, ISSN: 00219673
Reed J. Harris
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Isolation of cDNA clones encoding the mouse protein V-1
Gene, ISSN: 03781119
Diane Pennica; Kenneth J. Shaw; Shiuh-Ming Luoh; William I. Wood
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Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
David G Lowe; Alexander M. Dizhoor; Kathleen Liu; Qimin Gu; Maribeth Spencer; Richard Laura; Lucy Lu; James B. Hurley
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Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Austin L. Gurney; Suzan C. Wong; William J. Henzel; Frederic J. De Sauvage
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Identification of functionally important helical faces in transmembrane segments by scanning mutagenesis
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Geoffrey F. Lee; David P. Dutton; Gerald L. Hazelbauer
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Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Austin L. Gurney; Susan C. Wong; William J. Henzel; Frederic J. De Sauvage
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Theiler’s virus infection of 129Sv mice that lack the interferon α/ß or interferon γ receptors
Journal of Experimental Medicine, ISSN: 15409538 00221007
Laurence Fiette; Christine Aubert; Ulrike Müller; Sui Huang; Michel Aguet; Michel Brahic; Jean-François Bureau
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Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice
Journal of Experimental Medicine, ISSN: 15409538 00221007
Meera Subramaniam; Simin Saffaripour; Susan R. Watson; Tanya N. Mayadas; Richard O. Hynes; Denisa D. Wagner
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Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimai hyperplasia in balloon-injured rat carotid artery
Circulation, ISSN: 00097322
Takayuki Asahara; Christophe Bauters; Christopher Pastore; Marianne Kearney; Susan T. Rossow; Bunting; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner
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Recovery of disturbed endothelium-dependent flow in the collateral-perfused rabbit ischemic hindlimb after administration of vascular endothelial growth factor
Circulation, ISSN: 00097322
Christophe Bauters; Takayuki Asahara; Lu P. Zheng; Satoshi Takeshita; Bunting; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner
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Ecotin is a potent inhibitor of the contact system proteases factor XIIa and plasma kallikrein
FEBS Letters, ISSN: 00145793
Jana S. Ulmer; Robert N. Lindquist; Dennis; Lazarus
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Protective roles of cytokines against radiation: Induction of mitochondrial MnSOD
Biochimica et Biophysica Acta - Molecular Basis of Disease, ISSN: 09254439
Grace H.W. Wong
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Regulation of cell signaling by the cytoplasmic domains of the heat-stable enterotoxin receptor: Identification of autoinhibitory and activating motifs
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Xiaowen L. Rudner; Kathryn K. Mandal; Frederic J. De Sauvage; L. Allen Kindman; June S. Almenoff
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A mutant of melanoma growth stimulating activity does not activate neutrophils but blocks erythrocyte invasion by malaria
Journal of Biological Chemistry, ISSN: 00219258
Joseph Hesselgesser; Chitnis; Miller; Yansura; Laura C. Simmons; Wayne J. Fairbrother; Claire Kotts; Wirth; Beth Gillece-Castro; Richard Horuk
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Activation and Characterization of Procarboxypeptidase B from Human Plasma
Biochemistry, ISSN: 15204995 00062960
Tan; Dan L. Eaton
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The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon γ in vivo
Journal of Experimental Medicine, ISSN: 15409538 00221007
Vicki M. Eng; Bruce D. Car; Bruno Schnyder; Meike Lorenz; Serena Lugli; Michel Aguet; Timothy D. Anderson; Bernhard Ryffel; Valerie F. J. Quesniaux
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Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon γ and tumor necrosis factor α
Journal of Experimental Medicine, ISSN: 15409538 00221007
Inge E. A. Flesch; Jürgen H. Hess; Sui Huang; Michel Aguet; Joachim Rothe; Horst Bluethmann; Stefan H. E. Kaufmann
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The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Zhaohui Shao; Siegfried Ruppert; Paul D. Robbins
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A variant X-linked chronic granulomatous disease patient (X91+) with partially functional cytochrome b
Journal of Biological Chemistry, ISSN: 00219258
Andrew R. Cross; Heyworth; Julie Rae; John T. Curnutte
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Proton NMR Assignments and Solution Conformation of RANTES, a Chemokine of the C-C Type
Biochemistry, ISSN: 15204995 00062960
Nicholas J. Skelton; Fernando Aspiras; John R. Ogez; J. Schall Thomas
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