Genentech: Publications

January 1, 1999

A survey of the recent patent literature on the delivery of genes and oligonucleotides

Journal of Drug Targeting, ISSN: 1061186X

Mrsny

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January 1, 1999

Assessment of rhVEGF integrity in a photopolymerizable hydrogel

Proceedings of the Controlled Release Society, ISSN: 10220178

Duenas; Philbrook; Roth; Cleland

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January 1, 1999

Erratum: UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells (FEBS Letters 443 (1999) (326-330) PII: S001457939801713X)

FEBS Letters, ISSN: 00145793

Mao; Yu; Zhong; Wenlu Li; Brush; Steve Sherwood; Adams; Pan

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January 1, 1999

Receptor binding and biological activity of mammalian expressed sensory and motor neuron-derived factor (SMDF)

Growth Factors, ISSN: 08977194

Phyllis L. Osheroff; Siao Ping Tsai; Nancy Y. Chiang; King; Li; Gail D. Lewis; Kenneth Wong; William J. Henzel; Mather

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January 1, 1999

Regulation of Apo-2 ligand/TRAIL expression in NK cells - Involvement in NK cell-mediated cytotoxicity

Cytokine, ISSN: 10434666

Ann-Charlotte Johnsen; Johan Haux; Bjørg Steinkjer; Unni Nonstad; Kjartan Egeberg; Anders Sundan; Avi Ashkenazi; Espevik

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January 1, 1999

Single-administration vaccines: Controlled-release technology to mimic repeated immunizations

Trends in Biotechnology, ISSN: 01677799

Cleland

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January 1, 1999

Use of infrared spectroscopy to assess secondary structure of human growth hormone within biodegrable microspheres

Journal of Pharmaceutical Sciences, ISSN: 00223549

Tzung-Horng Yang; Aichun Dong; Jeffrey D. Meyer; OluFunmi Johnson; Cleland; John F. Carpenter

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January 1, 1999

Thrombopoietin (Tpo) in the fetus and neonate: Tpo concentrations in preterm and term neonates, and organ distribution of Tpo and its receptor (c-mpl) during human fetal development

Early Human Development, ISSN: 03783782

Martha C. Sola; Sandra E. Juul; Meng; Shaily Garg; Paul Sims; Darlene A. Calhoun; J. Benjamin Dame; Robert D. Christensen

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January 1, 1999

Pex17p is required for import of both peroxisome membrane and lumenal proteins and interacts with Pex19p and the peroxisome targeting signal- receptor docking complex in Pichia pastoris

Molecular Biology of the Cell, ISSN: 10591524

William B. Snyder; Antonius Koller; Aaron Jobu Choy; Monique A. Johnson; James M. Cregg; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani

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January 1, 1999

Pex19p interacts with Pex3p and Pex10p and is essential for peroxisome biogenesis in Pichia pastoris

Molecular Biology of the Cell, ISSN: 10591524

William B. Snyder; Klaas Nico Faber; Thibaut J. Wenzel; Antonius Koller; Georg H. Lüers; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani

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January 1, 1999

Role of baseline parameters in determining indirect pharmacodynamic responses

Journal of Pharmaceutical Sciences, ISSN: 00223549

Yu-Nien Sun; William J. Jusko

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January 1, 1999

Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease

Liver, ISSN: 01069543

Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Fong

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January 1, 1999

Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases

Brazilian Journal of Medical and Biological Research, ISSN: 1414431X 0100879X

Belizário; Steve Sherwood; Beçak

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January 1, 1999

Elastase substrate specificity tailored through substrate-assisted catalysis and phage display

Protein Engineering, ISSN: 02692139

William Dall'Acqua; Cornelia Halin; Maria L. Rodrigues; Paul J. Carter

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January 1, 1999

Somatotroph and lactotroph changes in the adenohypophyses of mice with disrupted insulin-like growth factor I gene

Endocrinology, ISSN: 00137227

Lucia Stefaneanu; Powell-Braxton; Wesley B. Won; Varadaraj Chandrashekar; Andrzej Bartke

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January 1, 1999

Analytical ultracentrifugation in the pharmaceutical industry

Journal of Pharmaceutical Sciences, ISSN: 00223549

Jun Liu; Steven J. Shire

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January 1, 1999

Selective cloning of cell surface proteins involved in organ development: Epithelial glycoprotein is involved in normal epithelial differentiation

Endocrinology, ISSN: 00137227

Jean-Philippe Stephan; Penelope E. Roberts; Bald; James Lee; Qimin Gu; Devaux; Mather

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January 1, 1999

Effects of Igf1 gene deletion on postnatal growth patterns

Endocrinology, ISSN: 00137227

Jie Wang; Jian Zhou; Powell-Braxton; Carolyn Bondy

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January 1, 1999

Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development

Endocrinology, ISSN: 00137227

Weifeng Ruan; Powell-Braxton; John J. Kopchick; David Kleinberg

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January 1, 1999

Estimating effectiveness in an observational study: A case study of dornase alfa in cystic fibrosis

Journal of Pediatrics, ISSN: 00223476

Charles A. Johnson; Butler; Michael W. Konstan; Timothy J. Breen; Morgan

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January 1, 1999

Capillary electrophoresis sodium dodecyl sulfate nongel sieving analysis of a therapeutic recombinant monoclonal antibody: A biotechnology perspective

Analytical Chemistry, ISSN: 00032700

Glenn Hunt; Wassim Nashabeh

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January 1, 1999

Heregulin enhances regenerative proliferation in postnatal rat utricular sensory epithelium after ototoxic damage

Journal of Neurocytology, ISSN: 03004864

Zheng; Gretchen D. Frantz; Lewis; Mark X. Sliwkowski; Gao

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January 1, 1999

VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain

Journal of Clinical Investigation, ISSN: 00219738

Nicholas Van Bruggen; Harold Thibodeaux; James T. Palmer; Wyne P. Lee; Ling Fu; Cairns; Daniel B. Tumas; Gerlai; Simon P. Williams; Menno Van Lookeren Campagne; Napoleone Ferrara

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January 1, 1999

Secondary reduction in the apparent diffusion coefficient of water, increase in cerebral blood volume, and delayed neuronal death after middle cerebral artery occlusion and early reperfusion in the rat

Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X

Menno Van Lookeren Campagne; Roger Thomas; Harold Thibodeaux; James T. Palmer; Simon P. Williams; David G Lowe; Nicholas Van Bruggen

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January 1, 1999

Anti-IgE as novel therapy for the treatment of asthma

Current Opinion in Pulmonary Medicine, ISSN: 10705287

Robert B. Fick Jr.

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January 1, 1999

RIPs: An emerging family of kinases involved in pro-inflammatory and apoptotic signaling

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Vishva M. Dixit

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January 1, 1999

Characterization of a candidate Borrella burgdorferi β3-chain integrin ligand identified using a phage display library

Molecular Microbiology, ISSN: 0950382X

Jenifer Coburn; Wambui Chege; Loranne Magoun; Bodary; John M. Leong

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January 1, 1999

Neuregulin receptor-mediated gene transfer by human epidermal growth factor receptor 2-targeted antibodies and neuregulin-1

Cancer Gene Therapy, ISSN: 09291903

Jeffrey Kern; Robert Wakita; Mark X. Sliwkowski

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January 1, 1999

Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease

Liver, ISSN: 01069543

Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Sherman Fong

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January 1, 1999

Intraocular pharmacokinetics and safety of a humanized monoclonal antibody in rabbits after intravitreal administration of a solution or a PLGA microsphere formulation

Toxicological Sciences, ISSN: 10966080

Joyce Mordenti; Karen Thomsen; Vojtech Licko; Lea Berleau; Jeanne Kahn; R. Andrew Cuthbertson; Duenas; Anne Ryan; Cheryl A. Schofield; Terrence W. Berger; Meng; Cleland

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January 1, 1999

Comparisons of the Intraocular Tissue Distribution, Pharmacokinetics, and Safety of 125I-Labeled Full-Length and Fab Antibodies in Rhesus Monkeys Following Intravitreal Administration

Toxicologic Pathology, ISSN: 01926233

Joyce Mordenti; R. Andrew Cuthbertson; Napoleone Ferrara; Karen Thomsen; Lea Berleau; Vojtech Licko; Philip C. Allen; Celia R. Valverde; Meng; David T.W. Fei; Kathleen M. Fourre; Anne Ryan

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January 1, 1999

Hypertension and endothelial dysfunction in apolipoprotein E knockout mice

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Renhui Yang; Powell-Braxton; Annie Ko Ogaoawara; Noel Dybdal; Bunting; Osamu Ohneda; Hongkui Jin

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January 1, 1999

A common mechanism for recombinant human NGF, BDNF, NT-3, and murine NGF slow unfolding

Protein Science, ISSN: 09618368

Linda R. De Young; Charles H. Schmelzer; Louis E. Burton

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January 1, 1999

Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus

Journal of Clinical Investigation, ISSN: 00219738

Ben-Gary Harvey; Philip L. Leopold; Neil R. Hackett; Tina M. Grasso; P. Mickey Williams; Ayly Ling Tucker; Robert J. Kaner; Barbara Ferris; Gonda; Sweeney; Ramachandran Ramalingam; Kovesdi; Steven Shak; Crystal

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January 1, 1999

Creatine: a review of efficacy and safety.

Journal of the American Pharmaceutical Association (Washington,D.C. : 1996), ISSN: 10865802

Graham; Hatton

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January 1, 1999

Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein soulless/Phox2a

Neuron, ISSN: 08966273

Guo; Brush; Hiroki Teraoka; Goddard; Stephen W. Wilson; Mary C. Mullins; Rosenthal

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January 1, 1999

Conformational changes in the activation loop of the insulin receptor's kinase domain

Protein Science, ISSN: 09618368

Mark Frankel; Steven M. Bishop; Ararat J. Ablooglu; Yuan-Ping Han; Ronald A. Kohanski

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January 1, 1999

Chromatography of recombinant proteins.

Developments in biological standardization, ISSN: 03015149

O'Connor

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January 1, 1999

Kinase Receptor Activation (KIRA): a rapid and accurate alternative to endpoint bioassays.

Developments in biological standardization, ISSN: 03015149

Michael D Sadick

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January 1, 1999

How much insulin-like growth factor-I (IGF-I) circulates?: impact of standardization on IGF-I assay accuracy.

Developments in biological standardization, ISSN: 03015149

Quarmby; Quan

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January 1, 1999

Evidence of anaphylaxy after alteplase infusion

Stroke, ISSN: 00392499

Jobst Rudolf; Martin Grond; Prince; Susanne Schmülling; Wolf-Dieter Heiss

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December 22, 1998

Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site

Biochemistry, ISSN: 00062960

Wayne J. Fairbrother; Hans W. Christinger; Andrea G Cochran; Fuh; Christopher J. Keenan; Quan; Stephanie K. Shriver; Jeffrey Tom; James A. Wells; Cunningham

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December 22, 1998

Crystal structure of the complex between VEGF and a receptor-blocking peptide

Biochemistry, ISSN: 00062960

Wiesmann; Hans W. Christinger; Andrea G Cochran; Cunningham; Wayne J. Fairbrother; Christopher J. Keenan; Meng; De Vos

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December 17, 1998

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

Nature, ISSN: 00280836

Pitti; Scot A. Marsters; David Lawrence; Margaret Roy; Frank C. Kischkel; Patrick Dowd; Arthur Huang; Christopher J. Donahue; Steve Sherwood; Daryl T. Baldwin; Godowski; William I. Wood; Austin L. Gurney; Kenneth J. Hillan; Robert L. Cohen; Goddard; David Botstein; Avi Ashkenazi

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December 15, 1998

Safety and immunogenicity of HIV recombinant envelope vaccines in HIV- infected infants and children

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, ISSN: 10779450

John S. Lambert; James McNamara; Samuel L. Katz; Terry Fenton; Minhee Kang; Thomas C. VanCott; Robert Livingston; Elizabeth Hawkins; Jack Moye Jr.; William Borkowsky; Daniel Johnson; Ram Yogev; A-M. Duliege; Francis; Anne Gershon; Diane W. Wara; Natasha L. Martin; Myron Levin; George McSherry; Gale Smith

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December 15, 1998

Crystal structure of the MATa1/MATα2 homeodomain heterodimer in complex with DNA containing an A-tract

Nucleic Acids Research, ISSN: 03051048

Thomas Li; Yisheng Jin; Andrew K. Vershon; Cynthia Wolberger

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December 15, 1998

Host defense molecule polymorphisms influence the risk for immune- mediated complications in chronic granulomatous disease

Journal of Clinical Investigation, ISSN: 00219738

Charles B. Foster; Thomas Lehrnbecher; Femke Mol; Seth M. Steinberg; David J. Venzon; Thomas J. Walsh; Noack; Julie Rae; Jerry A. Winkelstein; John T. Curnutte; Stephen J. Chanock

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December 14, 1998

Compendium of excipients for parenteral formulations

PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440

Powell; Tue H. Nguyen; Baloian

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December 11, 1998

Probing the importance of second sphere residues in an esterolytic antibody by phage display

Journal of Molecular Biology, ISSN: 00222836

Michelle R. Arkin; James A. Wells

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December 9, 1998