Genentech: Publications

January 1, 1999

Decreased CGRP, but preserved Trk A immunoreactivity in nerve fibres in inflamed human superficial temporal arteries

Journal of Neurology, Neurosurgery and Psychiatry, ISSN: 00223050

Saldanha; Hongo; Plant; Acheson; Levy; Anand

January 1, 1999

Preclinical safety evaluation of rhuMAbVEGF, an antiangiogenic humanized monoclonal antibody

Toxicologic Pathology, ISSN: 01926233

Anne Ryan; Dorothy Bates Eppler; Kelly E. Hagler; Richard H. Bruner; Peter J. Thomford; Robert L. Hall; Shopp; Charles A. O'Neill

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January 1, 1999

Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans

Toxicologic Pathology, ISSN: 01926233

Joyce Mordenti; Karen Thomsen; Vojtech Licko; Helen Chen; Meng; Napoleone Ferrara

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January 1, 1999

Biological actions of nerve growth factor in the peripheral nervous system

European Neurology, ISSN: 00143022

Cynthia A. Rask

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January 1, 1999

Role of tumor necrosis factor and interferon gamma in endotoxin-induced E-selectin expression

Shock, ISSN: 10732322

Michael J. Eppihimer; Janice Russell; Robert R. Langley; Mary E. Gerritsen; D. Neil Granger

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January 1, 1999

The GDNF protein family: Gene ablation studies reveal what they really do and how

Neuron, ISSN: 08966273

Rosenthal

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January 1, 1999

Evaluation of early computed tomographic findings in acute ischemic stroke

Stroke, ISSN: 00392499

Michael P. Marks; Holmgren; Allan J Fox; Suresh Patel; Rudiger Von Kummer; Froehlich

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January 1, 1999

Phage library-derived human anti-TETA and anti-DOTA scFv for pretargeting RIT

Hybridoma, ISSN: 0272457X

Sally J. DeNardo; Gerald L. DeNardo; Brush; Paul J. Carter

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January 1, 1999

Determination of low-molecular-mass antioxidant concentrations in human respiratory tract lining fluids

American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN: 10400605

Albert Van Der Vliet; Charles A. O'Neill; Carroll E. Cross; John M. Koostra; William G. Volz; Barry Halliwell; Samuel Louie

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January 1, 1999

On the structural preservation of recombinant human growth hormone in a dried film of a synthetic biodegradable polymer

Journal of Pharmaceutical Sciences, ISSN: 00223549

Karen G. Carrasquillo; Henry R. Costantino; Rocio A. Cordero; Chung C. Hsu; Kai Griebenow

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January 1, 1999

Growth hormone binding affinity for its receptor surpasses the requirements for cellular activity

Biochemistry, ISSN: 00062960

Kenneth H. Pearce Jr.; Cunningham; Fuh; Tuula Teeri; James A. Wells

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January 1, 1999

A cardioactive peptide from the southern armyworm, Spodoptera eridania

Peptides, ISSN: 01969781

Kenji Furuya; Murray Hackett; Marc A. Cirelli; Kathleen M. Schegg; Houle Wang; Jeffrey Shabanowitz; Donald F. Hunt; David A. Schooley

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January 1, 1999

The yeast a1 and α2 homeodomain proteins do not contribute equally to heterodimeric DNA binding

Molecular and Cellular Biology, ISSN: 02707306

Yisheng Jin; Hualin Zhong; Andrew K. Vershon

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January 1, 1999

Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565

Yvonne S. Lin; Cindy B. Nguyen; Jose-Luis Mendoza; Escandon; David T.W. Fei; Meng; Modi

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January 1, 1999

The optimal flow rate and column length for maximum production rate of protein A affinity chromatography

Bioprocess Engineering, ISSN: 0178515X

Fahrner; Harish V. Iyer; Gregory S. Blank

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January 1, 1999

Therapy of allergic pulmonary diseases with anti-IgE antibodies. A review

Pediatric Pulmonology, ISSN: 87556863

Robert B. Fick Jr.

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January 1, 1999

Consultation before thrombolytic therapy in acute myocardial infarction

American Journal of Cardiology, ISSN: 00029149

Nadim Al-Mubarak; William J. Rogers; Costas Lambrew; Laura J. Bowlby; William J. French

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January 1, 1999

A novel 96-well scintillation proximity assay for the measurement of apoptosis

Cytotechnology, ISSN: 09209069

Amy E. McMurtrey; Robert J. Graves; Jeff Hooley; Gerard Brophy; Gail D. Lewis Phillips

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January 1, 1999

VEGF loaded microspheres injected intramuscularly produce local neovascularization in normal, aged C57BL-6 mice

Proceedings of the Controlled Release Society, ISSN: 10220178

Daugherty; Hope Steinmetz; Hoeffel; Duenas; Tobin; Franklin V. Peale Jr.; Anne Ryan; Bunting; Cleland

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January 1, 1999

Antibody variable region binding by Staphylococcal protein A: Thermodynamic analysis and location of the Fv binding site on E-domain

Protein Science, ISSN: 09618368

Melissa A. Starovasnik; Mark P. O'Connell; Wayne J. Fairbrother; Robert F. Kelley

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January 1, 1999

Importance of VEGF for breast cancer angiogenesis in vivo: Implications from intravital microscopy of combination treatments with an anti-VEGF neutralizing monoclonal antibody and doxorubicin

Anticancer Research, ISSN: 02507005

Per Borgström; Daniel P. Gold; Kenneth J. Hillan; Napoleone Ferrara

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January 1, 1999

Vascular endothelial growth factor: Molecular and biological aspects

Current Topics in Microbiology and Immunology, ISSN: 0070217X

Napoleone Ferrara

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January 1, 1999

Reported in vivo spliced site mutations in the factor IX gene: Severity of splicing defects and a hypothesis for predicting deleterious splice donor mutations

Human Mutation, ISSN: 10597794

Rhett P. Ketterling; Joni B. Drost; William A. Scaringe; Dong-Zhou Liao; Jing-Zhong Liu; Carol K. Kasper; Steve S. Sommer

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January 1, 1999

Sialidase gene transfection enhances epidermal growth factor receptor activity in an epidermoid carcinoma cell line, A4311

Cancer Research, ISSN: 00085472

Emmanuelle J. Meuillet; Roger Kroes; Hirotaka Yamamoto; Warner; Ferrari; Barbara Mania-Farnell; David George; Abdelhadi Rebbaa; Joseph R. Moskal; Eric G. Bremer

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January 1, 1999

A survey of the recent patent literature on the delivery of genes and oligonucleotides

Journal of Drug Targeting, ISSN: 1061186X

Mrsny

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January 1, 1999

Assessment of rhVEGF integrity in a photopolymerizable hydrogel

Proceedings of the Controlled Release Society, ISSN: 10220178

Duenas; Philbrook; Roth; Cleland

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January 1, 1999

Erratum: UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells (FEBS Letters 443 (1999) (326-330) PII: S001457939801713X)

FEBS Letters, ISSN: 00145793

Mao; Yu; Zhong; Wenlu Li; Brush; Steve Sherwood; Adams; Pan

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January 1, 1999

Receptor binding and biological activity of mammalian expressed sensory and motor neuron-derived factor (SMDF)

Growth Factors, ISSN: 08977194

Phyllis L. Osheroff; Siao Ping Tsai; Nancy Y. Chiang; King; Li; Gail D. Lewis; Kenneth Wong; William J. Henzel; Mather

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January 1, 1999

Regulation of Apo-2 ligand/TRAIL expression in NK cells - Involvement in NK cell-mediated cytotoxicity

Cytokine, ISSN: 10434666

Ann-Charlotte Johnsen; Johan Haux; Bjørg Steinkjer; Unni Nonstad; Kjartan Egeberg; Anders Sundan; Avi Ashkenazi; Espevik

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January 1, 1999

Single-administration vaccines: Controlled-release technology to mimic repeated immunizations

Trends in Biotechnology, ISSN: 01677799

Cleland

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January 1, 1999

Use of infrared spectroscopy to assess secondary structure of human growth hormone within biodegrable microspheres

Journal of Pharmaceutical Sciences, ISSN: 00223549

Tzung-Horng Yang; Aichun Dong; Jeffrey D. Meyer; OluFunmi Johnson; Cleland; John F. Carpenter

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January 1, 1999

Thrombopoietin (Tpo) in the fetus and neonate: Tpo concentrations in preterm and term neonates, and organ distribution of Tpo and its receptor (c-mpl) during human fetal development

Early Human Development, ISSN: 03783782

Martha C. Sola; Sandra E. Juul; Meng; Shaily Garg; Paul Sims; Darlene A. Calhoun; J. Benjamin Dame; Robert D. Christensen

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January 1, 1999

Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases

Brazilian Journal of Medical and Biological Research, ISSN: 1414431X 0100879X

Belizário; Steve Sherwood; Beçak

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January 1, 1999

Evidence of anaphylaxy after alteplase infusion

Stroke, ISSN: 00392499

Jobst Rudolf; Martin Grond; Prince; Susanne Schmülling; Wolf-Dieter Heiss

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January 1, 1999

Role of baseline parameters in determining indirect pharmacodynamic responses

Journal of Pharmaceutical Sciences, ISSN: 00223549

Yu-Nien Sun; William J. Jusko

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January 1, 1999

Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease

Liver, ISSN: 01069543

Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Fong

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January 1, 1999

Pex17p is required for import of both peroxisome membrane and lumenal proteins and interacts with Pex19p and the peroxisome targeting signal- receptor docking complex in Pichia pastoris

Molecular Biology of the Cell, ISSN: 10591524

William B. Snyder; Antonius Koller; Aaron Jobu Choy; Monique A. Johnson; James M. Cregg; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani

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January 1, 1999

Pex19p interacts with Pex3p and Pex10p and is essential for peroxisome biogenesis in Pichia pastoris

Molecular Biology of the Cell, ISSN: 10591524

William B. Snyder; Klaas Nico Faber; Thibaut J. Wenzel; Antonius Koller; Georg H. Lüers; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani

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January 1, 1999

Elastase substrate specificity tailored through substrate-assisted catalysis and phage display

Protein Engineering, ISSN: 02692139

William Dall'Acqua; Cornelia Halin; Maria L. Rodrigues; Paul J. Carter

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January 1, 1999

Somatotroph and lactotroph changes in the adenohypophyses of mice with disrupted insulin-like growth factor I gene

Endocrinology, ISSN: 00137227

Lucia Stefaneanu; Powell-Braxton; Wesley B. Won; Varadaraj Chandrashekar; Andrzej Bartke

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January 1, 1999

Analytical ultracentrifugation in the pharmaceutical industry

Journal of Pharmaceutical Sciences, ISSN: 00223549

Jun Liu; Steven J. Shire

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January 1, 1999

Selective cloning of cell surface proteins involved in organ development: Epithelial glycoprotein is involved in normal epithelial differentiation

Endocrinology, ISSN: 00137227

Jean-Philippe Stephan; Penelope E. Roberts; Bald; James Lee; Qimin Gu; Devaux; Mather

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January 1, 1999

Effects of Igf1 gene deletion on postnatal growth patterns

Endocrinology, ISSN: 00137227

Jie Wang; Jian Zhou; Powell-Braxton; Carolyn Bondy

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January 1, 1999

Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development

Endocrinology, ISSN: 00137227

Weifeng Ruan; Powell-Braxton; John J. Kopchick; David Kleinberg

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January 1, 1999

Estimating effectiveness in an observational study: A case study of dornase alfa in cystic fibrosis

Journal of Pediatrics, ISSN: 00223476

Charles A. Johnson; Butler; Michael W. Konstan; Timothy J. Breen; Morgan

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January 1, 1999

Capillary electrophoresis sodium dodecyl sulfate nongel sieving analysis of a therapeutic recombinant monoclonal antibody: A biotechnology perspective

Analytical Chemistry, ISSN: 00032700

Glenn Hunt; Wassim Nashabeh

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January 1, 1999

Heregulin enhances regenerative proliferation in postnatal rat utricular sensory epithelium after ototoxic damage

Journal of Neurocytology, ISSN: 03004864

Zheng; Gretchen D. Frantz; Lewis; Mark X. Sliwkowski; Gao

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January 1, 1999

VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain

Journal of Clinical Investigation, ISSN: 00219738

Nicholas Van Bruggen; Harold Thibodeaux; James T. Palmer; Wyne P. Lee; Ling Fu; Cairns; Daniel B. Tumas; Gerlai; Simon P. Williams; Menno Van Lookeren Campagne; Napoleone Ferrara

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January 1, 1999

Secondary reduction in the apparent diffusion coefficient of water, increase in cerebral blood volume, and delayed neuronal death after middle cerebral artery occlusion and early reperfusion in the rat

Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X

Menno Van Lookeren Campagne; Roger Thomas; Harold Thibodeaux; James T. Palmer; Simon P. Williams; David G Lowe; Nicholas Van Bruggen

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January 1, 1999

Anti-IgE as novel therapy for the treatment of asthma

Current Opinion in Pulmonary Medicine, ISSN: 10705287

Robert B. Fick Jr.

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