Genentech: Publications

March 13, 1996

Aggregation of rhDNase occurred during the compression of KBr pellets used for FTIR spectroscopy

Pharmaceutical Research, ISSN: 07248741

Chan; Ongpipattanakul; Jacky Au-Yeung

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March 8, 1996

TAFII250 is a bipartite protein kinase that phosphorylates the basal transcription factor RAP74

Cell, ISSN: 00928674

Rivka Dikstein; Siegfried Ruppert; Robert Tjian

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March 8, 1996

Participation of JAK and STAT proteins in growth hormone-induced signaling

Journal of Biological Chemistry, ISSN: 00219258

Yulong Han; Douglas W. Leaman; Diane Watling; Neil C. Rogers; Bernd Groner; Ian M. Kerr; William I. Wood; George R. Stark

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March 8, 1996

Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors: Generation of receptor-selective VEGF variants by site-directed mutagenesis

Journal of Biological Chemistry, ISSN: 00219258

Keyt; Hung V. Nguyen; Lea Berleau; Carlos M. Duarte; Jeanie Park; Helen Chen; Napoleone Ferrara

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March 5, 1996

Vascular endothelial growth factor-related protein: A ligand and specific activator of the tyrosine kinase receptor Flt4

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James Lee; Gray; Jean Q. Yuan; Shiuh-Ming Luoh; Hava Avraham; William I. Wood

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March 1, 1996

Expression and regulation of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in distinct avian motoneuron subsets

Journal of Neurobiology, ISSN: 00223034

Nitza Kahane; David L. Shelton; Chaya Kalcheim

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March 1, 1996

Critical amino acids in the lymphocyte function-associated antigen-1 I domain mediate intercellular adhesion molecule 3 binding and immune function

Journal of Experimental Medicine, ISSN: 00221007

Yvette Van Kooyk; Minke E. Binnerts; Caroline P. Edwards; Mark Champe; Berman; Carl G. Figdor; Bodary

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March 1, 1996

Reproductive toxicity testing of therapeutic biotechnology agents

Teratology, ISSN: 00403709

Judith W. Henck; Kim G. Hilbish; Mercedes A. Serabian; Joy A. Cavagnaro; Andrew G. Hendrickx; Narsingh D. Agnish; Ada H.C. Kung; Joyce Mordenti

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March 1, 1996

Transforming growth factor β1 induces angiogenesis in vivo with a threshold pattern

Laboratory Investigation, ISSN: 00236837

Luis F. Fajardo; Stavros D. Prionas; Helen H. Kwan; Joe Kowalski; Anthony C. Allison

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March 1, 1996

The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins

Nature Genetics, ISSN: 10614036

Tom A. Ebersole; Qi Chen; Monica J. Justice; Karen Artzt

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March 1, 1996

The effect of variance function estimation on nonlinear calibration inference in immunoassay data

Biometrics, ISSN: 0006341X

Bruce A. Belanger; Davidian; Giltinan

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February 28, 1996

Systematic improvement of a chemically-defined protein-free medium for hybridoma growth and monoclonal antibody production

Journal of Biotechnology, ISSN: 01681656

Stoll; Mühlethaler; Von Stockar; Ian W. Marison

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February 23, 1996

IRAK: A kinase associated with the interleukin-1 receptor

Science, ISSN: 00368075

Zhaodan Cao; William J. Henzel; Xiong Gao

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February 20, 1996

Decreased food intake does not completely account for adiposity reduction after ob protein infusion

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Nancy Levin; Nelson; Austin L. Gurney; Richard Vandleni; Frederic J. De Sauvage

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February 20, 1996

Biological and immunological characterization of inhibin forms in human plasma

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Robertson; Burger; Sullivan; Cahir; Nigel P. Groome; Poncelet; Franchimont; Woodruff; Mather

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February 16, 1996

The Crystal Structure of the Extracellular Domain of Human Tissue Factor Refined to 1.7 Å Resolution

Journal of Molecular Biology, ISSN: 00222836

Yves A. Muller; Ultsch; De Vos

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February 16, 1996

Strategies for manipulating apoptosis for cancer therapy with tumor necrosis factor and lymphotoxin

Journal of Cellular Biochemistry, ISSN: 07302312

Grace H.W. Wong; Roger L. Kaspar; Gary Zweiger; Carlson; Fong; Niloofar Ehsani; Gordon A. Vehar

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February 15, 1996

Macrophage-mediated apoptosis in the developing mouse eye

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Graciana Diez-Roux; Mark Labow; Horst Bluthman; Mark Moore; Richard Lang

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February 15, 1996

Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth

Cancer Research, ISSN: 00085472

Ostap Melnyk; Shuman; K.Jin Kim

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February 15, 1996

Tear Hepatocyte Growth Factor (HGF) production increases markedly after excimer laser photorefractive keratoplasty (PRK)

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Qianwa Liang; Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Marco Helena; Wilson

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February 15, 1996

Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat: A combined in vivo and in vitro evaluation

Circulation, ISSN: 00097322

Antonio Cittadini; Hinrik Strömer; Sarah E. Katz; Ross Clark; Alan C. Moses; James P. Morgan; Pamela Douglas

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February 15, 1996

HGF and HGF receptor expresion in the lacrimal gland

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Mohan; Li; Weng; Bennett; Ralph H. Schwall; Wang; Tabor; Kim; Hargrave; Cuevas; Wilson

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February 13, 1996

Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: Identification and effect on binding affinity

Biochemistry, ISSN: 00062960

Cacia; Rodney Keck; Presta; John Frenz

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February 10, 1996

A model for metal affinity protein precipitation

Journal of Colloid and Interface Science, ISSN: 00219797

Harish V. Iyer; Todd M. Przybycien

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February 9, 1996

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

Cell, ISSN: 00928674

Marco A. Meraz; J. Michael White; Kathleen C. Sheehan; Bach; Scott J. Rodig; Anand S. Dighe; Daniel H. Kaplan; Riley; Andrew C. Greenlund; Dayle Campbell; Karen Carver-Moore; Raymond N. DuBois; Ross Clark; Michel Aguet; Schreiber

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February 8, 1996

High level secretion of a humanized bispecific diabody from Escherichia coli

Bio/Technology, ISSN: 0733222X

Zhu; Gerardo Zapata; Shalaby; Snedecor; Man Chert; Paul J. Carter

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February 1, 1996

Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma

Cell Growth and Differentiation, ISSN: 10449523

Nader Rahimi; Eric Tremblay; Laura McAdam; Marg Park; Ralph H. Schwall; Bruce Elliott

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February 1, 1996

Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival

Development (Cambridge), ISSN: 09501991

Zelin Sheng; Diane Pennica; William I. Wood; Kenneth R. Chien

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February 1, 1996

Electrophoretic separation of recombinant tissue-type plasminogen activator glycoforms: Validation issues for capillary isoelectric focusing methods

Electrophoresis, ISSN: 01730835

Kathy Moorhouse; Carina A. Rickel; Chen

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February 1, 1996

The in vivo bioactivity of vascular endothelial growth factor/vascular permeability factor is independent of N-linked glycosylation

Laboratory Investigation, ISSN: 00236837

Dirk H. Walter; Uli Hink; Takayuki Asahara; Eric Van Belle; Jeffrey Horowitz; Yukio Tsurumi; Richard L. Vandlen; Heinsohn; Keyt; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner

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February 1, 1996

Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin

Journal of Experimental Medicine, ISSN: 00221007

Frederic J. De Sauvage; Karen Carver-Moore; Shiuh-Ming Luoh; Anne Ryan; Mary Dowd; Dan L. Eaton; Mark Moore

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January 31, 1996

Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice

International Immunology, ISSN: 09538178

Hans-Pietro Eugster; Matthias Müller; Urs Karrer; Bruce D. Car; Bruno Schnyder; Vicki M. Eng; Gaetane Woerly; Michel Le Hir; Franco Di Padova; Michel Aguet; Rolf M. Zinkernagel; Horst Bluethmann; Bernhard Ryffel

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January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Scott Cooper; Hague; Mark Moore; Lasky

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January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Cooper; Hague; Mark Moore; Lasky

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January 15, 1996

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

Journal of Clinical Investigation, ISSN: 00219738

Edi Brogi; Gina Schatteman; Tiangen Wu; Elizabeth A. Kim; Lyuba Varticovski; Keyt; Jeffrey M. Isner

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January 11, 1996

Pharmacokinetics and pharmacodynamics of TP-9201, a gpIIbIIIa antagonist, administered in combination with recombinant tissue-type plasminogen activator, heparin, and aspirin in beagles

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Modi; Theresa Reynolds; Sharon A. Baughman; Deborah A. Thomas; Paasch; Susan Yvonne Smith

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January 11, 1996

Vascular endothelial growth factor augments muscle blood flow and function in a rabbit model of chronic hindlimb ischemia

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Walder; Carol J. Errett; Bunting; Peter Lindquist; John R. Ogez; Heinsohn; Napoleone Ferrara; G. Roger Thomas

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January 9, 1996

Binding in the growth hormone receptor complex

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James A. Wells

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January 4, 1996

Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1 H and natural abundance 13 C NMR spectroscopy

Carbohydrate Research, ISSN: 00086215

Neil E. Jacobsen; Wayne J. Fairbrother; Kensil; Lim; Deborah A. Wheeler; Powell

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January 1, 1996

Effects of 12-week administration of dornase alfa in patients with advanced cystic fibrosis lung disease

Chest, ISSN: 00123692

Karen McCoy; Scott Hamilton; Charles A. Johnson

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January 1, 1996

Trophic factors and their role in the postischemic brain.

Advances in neurology, ISSN: 00913952

Nikolics; Franz Hefti; Thomas; Gluckman

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January 1, 1996

A novel tumor-derived mediator that sensitizes cytokine-resistant tumors to tumor necrosis factor

Journal of Surgical Research, ISSN: 00224804

Michael R. Marvin; Steven K. Libutti; Mark Kayton; Janet Kao; Joanne Hayward; Tracy Grikscheit; Yan-G. Fan; Jerold Brett; Weinberg; Roman Nowygrod; Paul Logerfo; Carl Feind; Kristen S. Hansen; Margaret A. Schwarz; David Stern; John Chabot

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January 1, 1996

X-CGDbase: A database of X-CGD-causing mutations

Immunology Today, ISSN: 01675699

Dirk Roosl; John T. Curnutte; Johann Peter Hossle; Yu Lung Lau; Tadashi Ariga; Hiroyuki Nunoi; Mary C. Dinauer; Manfred Gahr; Anthony W. Segal; Peter E. Newburger; Mauro Giacca; Nicholas H. Keep; Rob Van Zwieten

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January 1, 1996

Carbohydrate metabolism in children receiving growth hormone for 5 years: Chronic renal insufficiency compared with growth hormone deficiency, Turner syndrome, and idiopathic short stature

Pediatric Nephrology, ISSN: 0931041X

Saenger; Kenneth M. Attie; Dimartino-Nardi; Richard N. Fine

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January 1, 1996

Immunoadhesins: Principles and applications

Trends in Biotechnology, ISSN: 01677799

Steven M. Chamow; Avi Ashkenazi

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January 1, 1996

Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate

Archives of Ophthalmology, ISSN: 00039950

Anthony P. Adamis; David T. Shima; Michael J. Tolentino; Evangelos S. Gragoudas; Napoleone Ferrara; Judah Folkman; Patricia A. D'Amore; Joan W. Miller

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January 1, 1996

Pharmacokinetics and interspecies scaling of recombinant human factor VIII

Toxicology and Applied Pharmacology, ISSN: 0041008X

Joyce Mordenti; Gary Osaka; Kit Garcia; Karen Thomsen; Vojtech Licko; Gloria Meng

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January 1, 1996

Microencapsulation reactor scale-up by dimensional analysis

Journal of Microencapsulation, ISSN: 02652048

Maa; Chung C. Hsu

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January 1, 1996