Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13151 - 13200 OF 15572 RESULTS

January 1, 1996

Substitution of serine or threonine at position 473 of tissue-type plasminogen activator increases its stability in plasma

Thrombosis and Haemostasis, ISSN: 03406245

Murtaza Alibhai; Alice M. Chow; Nicholas F. Paoni

January 1, 1996

Identification of G-protein binding sites of the human interleukin-8 receptors by functional mapping of the intracellular loops

FASEB Journal, ISSN: 08926638

Bassam B. Damaj; Shaun R. McColl; Kuldeep Neote; Songqing; Kevin T. Ogborn; Hébert; Paul H. Naccache

January 1, 1996

Overview: Direct antithrombins and their therapeutic potential

Coronary Artery Disease, ISSN: 09546928

David Stump

January 1, 1996

Murine cardiotrophin-1 stimulates the acute-phase response in rat hepatocytes and H35 hepatoma cells

Journal of Interferon and Cytokine Research, ISSN: 10799907

Richards; Langdon; Diane Pennica; Gauldie

January 1, 1996

Caco-2 monolayers as a tool to examine intestinal uptake of particulates

Proceedings of the Controlled Release Society, ISSN: 10220178

Delie; Rubas

January 1, 1996

Characterization of upper respiratory disease in rats following neonatal inoculation with a rat-adapted influenza virus

Veterinary Pathology, ISSN: 03009858

Dye; Morgan; Neldon; Tepper; Burleson; Costa

January 1, 1996

Evaluation of interleukin-1. Receptor antagonist (IL-1RA) and tumor necrosis factor binding protein (TNF-BP) in a rodent abscess model of host resistance

Immunopharmacology and Immunotoxicology, ISSN: 08923973

Colagiovanni; Shopp

January 1, 1996

Isomerization and formulation stability of the vaccine adjuvant QS-21

Journal of Pharmaceutical Sciences, ISSN: 00223549

Cleland; Kensil; Lim; Neil E. Jacobsen; Basa; Spellman; Deborah A. Wheeler; Jia-Yan Wu; Powell

January 1, 1996

Full-length agrin isoform activities and binding site distributions on cultured Xenopus muscle cells

Molecular and Cellular Neuroscience, ISSN: 10447431

David F. Daggett; Donna Stone; H. Benjamin Peng; Nikolics

January 1, 1996

Development of recombinant human nerve growth factor (rhNGF) as a treatment for peripheral neuropathic disease

NeuroToxicology, ISSN: 0161813X

Rogers

January 1, 1996

Baylisascaris procyonis larva migrans in a puppy: A case report and update for the veterinarian

Journal of the American Animal Hospital Association, ISSN: 05872871

Daniel G. Rudmann; Kevin R. Kazacos; Scott T. Storandt; Donna L. Harris; Evan B. Janovitz

January 1, 1996

Vinblastine, a substrate for P-glycoprotein, flux across Caco-2 monolayers and rabbit jejunum

Proceedings of the Controlled Release Society, ISSN: 10220178

Mah; Rubas

January 1, 1996

Design and application of a low-temperature Peltier-cooling microscope stage

Journal of Pharmaceutical Sciences, ISSN: 00223549

Chung C. Hsu; Andrew J. Walsh; Hoc M. Nguyen; David E. Overcashier; Hans Koning-Bastiaan; Ralph C. Bailey; Steven L. Nail

January 1, 1996

Gene targeting in neuroscience: The systemic approach

Trends in Neurosciences, ISSN: 01662236

Gerlai

January 1, 1996

Protection of MN-rgp120-immunized chimpanzees from heterologous infection with a primary isolate of human immunodeficiency virus type 1

Journal of Infectious Diseases, ISSN: 00221899

Berman; Murthy; Wrin; Vennari; Kathy Cobb; Eastman; Mark Champe; Nakamura; Donna Davison; Powell; Bussiere; Francis; Matthews; Timothy Gregory; John F. Obijeski

January 1, 1996

Penicillamine: An extractable chiral auxiliary providing excellent stereocontrol

Tetrahedron Asymmetry, ISSN: 09574166

Lutz S. Richter; Thomas Gadek

January 1, 1996

Flux measurements across Caco-2 monolayers may predict transport in human large intestinal tissue

Journal of Pharmaceutical Sciences, ISSN: 00223549

Rubas; Cromwell; Shahrokh; Villagran; Nguyen; Wellton; Tue H. Nguyen; Mrsny

January 1, 1996

Multicopy suppressors of prc mutant Escherichia coli include two HtrA (DegP) protease homologs (HhoAB), DksA, and a truncated rlpA

Journal of Bacteriology, ISSN: 00219193

Bass; Qimin Gu; Anthony Christen

January 1, 1996

Liquid-liquid emulsification by rotor/stator homogenization

Journal of Controlled Release, ISSN: 01683659

Maa; Chung C. Hsu

January 1, 1996

Human cardiotrophin-1: Protein and gene structure, biological and binding activities, and chromosomal localization

Cytokine, ISSN: 10434666

Diane Pennica; Todd A. Swanson; Kenneth J. Shaw; Wun-Jing Kuang; Christa Gray; Barbara G. Beatty; William I. Wood

January 1, 1996

Locating the unpaired cysteine of tissue-type plasminogen activator

Protein Engineering, ISSN: 02692139

Louis C. Sehl; Hung V. Nguyen; Lea Berleau; Patricia Arcila; William F. Bennett; Keyt

January 1, 1996

Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons

Molecular and Cellular Neuroscience, ISSN: 10447431

Goodman; Janet Valverde; Filip Lim; Michael D. Geschwind; Howard J. Federoff; Alfred I. Geller; Franz Hefti

January 1, 1996

GDNF induces a dystonia-like state in neonatal rats and stimulates dopamine and serotonin synthesis

Neuron, ISSN: 08966273

Klaus D. Beck; Ian Irwin; Janet Valverde; Thomas J. Brennan; J. William Langston; Franz Hefti

January 1, 1996

Follistatins and α2-macroglobulin are soluble binding proteins for inhibinand activin

Hormone Research, ISSN: 16632826 16632818

Mather

January 1, 1996

Vascular endothelial growth factor, a specific regulator of angiogenesis

Current Opinion in Nephrology and Hypertension, ISSN: 10624821

Napoleone Ferrara; Bunting

January 1, 1996

186Re-labeled antibodies to p185HER2 as HER2-targeted radioimmunopharmaceutical agents: Comparison of physical and biological characteristics with 125I and 131I-labeled counterparts

Cancer Biotherapy and Radiopharmaceuticals, ISSN: 10849785

Claire Kotts; Su; Cecilia Leddy; Dodd; Scates; Shalaby; Wirth; Giltinan; Schroff; Fritzberg; Shepard; Dennis J. Slamon; Hutchins

January 1, 1996

Regulation of transplacental virus infection by developmental and immunological factors: Studies with lactate dehydrogenase-elevating virus

Virus Research, ISSN: 01681702

Thomas R. Haven; Raymond R.R. Rowland; Peter G. W. Plagemann; Grace H.W. Wong; Sarahann E. Bradley; William A. Cafruny

January 1, 1996

Hematologically important mutations: X-Linked chronic granulomatous disease

Blood Cells, Molecules, and Diseases, ISSN: 10799796

Andrew R. Cross; John T. Curnutte; Julie Rae; Heyworth

January 1, 1996

Hepatocyte proliferation and serum hepatocyte growth factor levels in patients with alcoholic hepatitis

Journal of Hepatology, ISSN: 01688278

Kenneth J. Hillan; Martin C. Logan; Rod K. Ferrier; George L. Bird; Bennett; Ian C. McKay; Roderick N. M. MacSween

January 1, 1996

Structural elucidation of O-linked glycopeptides by high energy collision-induced dissociation

Journal of the American Society for Mass Spectrometry, ISSN: 10440305

Medzihradszky; Beth Gillece-Castro; Townsend; Alma Burlingame; Hardy

January 1, 1996

A composite view of cardiac rupture in the United States National Registry of Myocardial Infarction

Journal of the American College of Cardiology, ISSN: 07351097

Richard C. Becker; Joel M. Gore; Costas Lambrew; W.Douglas Weaver; R. Michael Rubison; William J. French; Alan J. Tiefenbrunn; Laura J. Bowlby; William J. Rogers

January 1, 1996

Differential long-term effects of insulin-like growth factor-I (IGF-I), growth hormone (GH), and IGF-I plus GH on body growth and IGF binding proteins in hypophysectomized rats

Endocrinology, ISSN: 00137227

Fielder; Deborah L. Mortensen; Phyllis Mallet; Carlsson; Baxter; Ross Clark

January 1, 1996

Binding of cynomolgus monkey IgE to a humanized anti-human IgE antibody and human high affinity IgE receptor

Molecular Immunology, ISSN: 01615890

Meng; Naina Singh; Wai Lee T. Wong

January 1, 1996

Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype?

Trends in Neurosciences, ISSN: 01662236

Gerlai

January 1, 1996

An experimental model of intracranial hemorrhage during thrombolytic therapy with t-PA

Thrombosis and Haemostasis, ISSN: 03406245

Nicholas F. Paoni; Hope Steinmetz; Nancy Gillett; Refino; Julie M. Badillo; Bunting

January 1, 1996

Transforming growth factor-β1 stimulates bone ongrowth to weight-loaded tricalcium phosphate coated implants: An experimental study in dogs

Journal of Bone and Joint Surgery - Series B, ISSN: 0301620X

Martin Lind; Søren Overgaard; Ongpipattanakul; Tue H. Nguyen; Cody Bünger; Kjeld Søballe

January 1, 1996

The obese growth hormone (GH)-deficient dwarf rat: Body fat responses to patterned delivery of GH and insulin-like growth factor-I

Endocrinology, ISSN: 00137227

Ross Clark; Deborah L. Mortensen; Carlsson; Carlsson; Carmignac; Icaf Robinson

January 1, 1996

Binders from the Deepest Vaults

Nature Biotechnology, ISSN: 15461696 10870156

Paul J. Carter

January 1, 1996

Developmental differences in the IGF-I system response to severe and chronic calorie malnutrition

American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849

Oster; Nancy Levin; Fielder; Icaf Robinson; Baxter; Cronin

January 1, 1996

Translational level is a critical factor for the secretion of heterologous proteins in escherichia coli

Nature Biotechnology, ISSN: 15461696 10870156

Laura C. Simmons; Yansura

January 1, 1996

Utility of the National Cooperative Growth Study database for safety reporting

Journal of Pediatrics, ISSN: 00223476

David Graves

January 1, 1996

Novel assays based on human growth hormone receptor as alternatives to the rat weight gain bioassay for recombinant human growth hormone

Biologicals, ISSN: 10451056

Roswall; Mukku; Chen; Hoff; Chu; McKay; Olson; John E. Battersby; Richard L. Gehant; Meunier; Robert L. Garnick

January 1, 1996

Ligand-induced assembly and activation of the gamma interferon receptor in intact cells

Molecular and Cellular Biology, ISSN: 02707306

Bach; William Tanner; Scot A. Marsters; Avi Ashkenazi; Michel Aguet; Andrey S. Shaw; Schreiber

January 1, 1996

Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by intrastriatal 6-hydroxydopamine in the rat

Neuroscience, ISSN: 03064522

Lee; Hans Sauer; Anders Bjorklund

January 1, 1996

Pharmacokinetics, tissue distribution, and expression Efficiency of plasmid [33P]DNA following intravenous administration of DNA/cationic lipid complexes in mice: Use of a novel radionuclide approach

Journal of Pharmaceutical Sciences, ISSN: 00223549

Gary Osaka; Kendall Carey; R. Andrew Cuthbertson; Godowski; Thomas W. Patapoff; Anne Ryan; Thomas Gadek; Joyce Mordenti

January 1, 1996

The contribution of gene manipulation techniques to understanding dorsoventral patterning in the vertebrate nervous system

Seminars in Neuroscience, ISSN: 10445765

Mary Hynes; Rosenthal

January 1, 1996

Oxidant generation and lung injury after particulate air pollutant exposure increase with the concentrations of associated metals

Inhalation Toxicology, ISSN: 08958378

Robert J. Pritchard; Andrew J. Ghio; James R. Lehmann; Winsett; Tepper; Patricia Park; M. Ian Gilmour; Kevin Dreher; Costa

January 1, 1996

Cell culture engineering.

Trends in Biotechnology, ISSN: 01677799

Robert Kiss

January 1, 1996

Neuronal chain gangs: Homotypic contacts support migration into the olfactory bulb

Neuron, ISSN: 08966273

Nancy A. O'Rourke

January 1, 1996

Chiral kinetics and dynamics of ketorolac

Journal of Clinical Pharmacology, ISSN: 00912700

Edward Mroszczak; Daniel Combs; Melvin Chaplin; Irene Tsina; Thomas Tarnowski; Cynthia Rocha; Yuen Tam; Aileen Boyd; John Young; Linval Depass

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