Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13301 - 13350 OF 15758 RESULTS

February 20, 1996

Decreased food intake does not completely account for adiposity reduction after ob protein infusion

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Nancy Levin; Nelson; Austin L. Gurney; Richard Vandleni; Frederic J. De Sauvage

February 16, 1996

Strategies for manipulating apoptosis for cancer therapy with tumor necrosis factor and lymphotoxin

Journal of Cellular Biochemistry, ISSN: 07302312

Grace H.W. Wong; Roger L. Kaspar; Gary Zweiger; Carlson; Fong; Niloofar Ehsani; Gordon A. Vehar

February 16, 1996

The Crystal Structure of the Extracellular Domain of Human Tissue Factor Refined to 1.7 Å Resolution

Journal of Molecular Biology, ISSN: 00222836

Yves A. Muller; Ultsch; De Vos

February 15, 1996

HGF and HGF receptor expresion in the lacrimal gland

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Mohan; Li; Weng; Bennett; Ralph H. Schwall; Wang; Tabor; Kim; Hargrave; Cuevas; Wilson

February 15, 1996

Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat: A combined in vivo and in vitro evaluation

Circulation, ISSN: 00097322

Antonio Cittadini; Hinrik Strömer; Sarah E. Katz; Ross Clark; Alan C. Moses; James P. Morgan; Pamela Douglas

February 15, 1996

Tear Hepatocyte Growth Factor (HGF) production increases markedly after excimer laser photorefractive keratoplasty (PRK)

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Qianwa Liang; Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Marco Helena; Wilson

February 15, 1996

Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth

Cancer Research, ISSN: 00085472

Ostap Melnyk; Shuman; K.Jin Kim

February 15, 1996

Macrophage-mediated apoptosis in the developing mouse eye

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Graciana Diez-Roux; Mark Labow; Horst Bluthman; Mark Moore; Richard Lang

February 13, 1996

Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: Identification and effect on binding affinity

Biochemistry, ISSN: 00062960

Cacia; Rodney Keck; Presta; John Frenz

February 10, 1996

A model for metal affinity protein precipitation

Journal of Colloid and Interface Science, ISSN: 00219797

Harish V. Iyer; Todd M. Przybycien

February 9, 1996

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

Cell, ISSN: 00928674

Marco A. Meraz; J. Michael White; Kathleen C. Sheehan; Bach; Scott J. Rodig; Anand S. Dighe; Daniel H. Kaplan; Riley; Andrew C. Greenlund; Dayle Campbell; Karen Carver-Moore; Raymond N. DuBois; Ross Clark; Michel Aguet; Schreiber

February 8, 1996

High level secretion of a humanized bispecific diabody from Escherichia coli

Bio/Technology, ISSN: 0733222X

Zhu; Gerardo Zapata; Shalaby; Snedecor; Man Chert; Paul J. Carter

February 1, 1996

Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin

Journal of Experimental Medicine, ISSN: 00221007

Frederic J. De Sauvage; Karen Carver-Moore; Shiuh-Ming Luoh; Anne Ryan; Mary Dowd; Dan L. Eaton; Mark Moore

February 1, 1996

The in vivo bioactivity of vascular endothelial growth factor/vascular permeability factor is independent of N-linked glycosylation

Laboratory Investigation, ISSN: 00236837

Dirk H. Walter; Uli Hink; Takayuki Asahara; Eric Van Belle; Jeffrey Horowitz; Yukio Tsurumi; Richard L. Vandlen; Heinsohn; Keyt; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner

February 1, 1996

Electrophoretic separation of recombinant tissue-type plasminogen activator glycoforms: Validation issues for capillary isoelectric focusing methods

Electrophoresis, ISSN: 01730835

Kathy Moorhouse; Carina A. Rickel; Chen

February 1, 1996

Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival

Development (Cambridge), ISSN: 09501991

Zelin Sheng; Diane Pennica; William I. Wood; Kenneth R. Chien

February 1, 1996

Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma

Cell Growth and Differentiation, ISSN: 10449523

Nader Rahimi; Eric Tremblay; Laura McAdam; Marg Park; Ralph H. Schwall; Bruce Elliott

January 31, 1996

Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice

International Immunology, ISSN: 09538178

Hans-Pietro Eugster; Matthias Müller; Urs Karrer; Bruce D. Car; Bruno Schnyder; Vicki M. Eng; Gaetane Woerly; Michel Le Hir; Franco Di Padova; Michel Aguet; Rolf M. Zinkernagel; Horst Bluethmann; Bernhard Ryffel

January 15, 1996

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

Journal of Clinical Investigation, ISSN: 00219738

Edi Brogi; Gina Schatteman; Tiangen Wu; Elizabeth A. Kim; Lyuba Varticovski; Keyt; Jeffrey M. Isner

January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Cooper; Hague; Mark Moore; Lasky

January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Scott Cooper; Hague; Mark Moore; Lasky

January 11, 1996

Vascular endothelial growth factor augments muscle blood flow and function in a rabbit model of chronic hindlimb ischemia

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Walder; Carol J. Errett; Bunting; Peter Lindquist; John R. Ogez; Heinsohn; Napoleone Ferrara; G. Roger Thomas

January 11, 1996

Pharmacokinetics and pharmacodynamics of TP-9201, a gpIIbIIIa antagonist, administered in combination with recombinant tissue-type plasminogen activator, heparin, and aspirin in beagles

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Modi; Theresa Reynolds; Sharon A. Baughman; Deborah A. Thomas; Paasch; Susan Yvonne Smith

January 9, 1996

Binding in the growth hormone receptor complex

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James A. Wells

January 4, 1996

Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1 H and natural abundance 13 C NMR spectroscopy

Carbohydrate Research, ISSN: 00086215

Neil E. Jacobsen; Wayne J. Fairbrother; Kensil; Lim; Deborah A. Wheeler; Powell

January 1, 1996

Effects of 14-day infusions of growth hormone and/or insulin-like growth factor I on the obesity of growing Zucker rats

Endocrinology, ISSN: 00137227

Dubuis; Deal; Tsagaroulis; Ross Clark; Van Vliet

January 1, 1996

Cardiotrophin-1, a cytokine present in embryonic muscle, supports long- term survival of spinal motoneurons

Neuron, ISSN: 08966273

Diane Pennica; Vilma Arce; Todd A. Swanson; Richard Vejsada; Richard A. Pollock; Armanini; Dudley; Phillips; Rosenthal; Ann C. Kato; Christopher E. Henderson

January 1, 1996

Cardiotrophin-1: A multifunctional cytokine that signals via LIF receptor-gp130 dependent pathways

Cytokine and Growth Factor Reviews, ISSN: 13596101

Diane Pennica; William I. Wood; Kenneth R. Chien

January 1, 1996

The bglX gene located at 47.8 min on the Escherichia coli chromosome encodes a periplasmic β-glucosidase

Microbiology, ISSN: 13500872

Yang; Shiuh-Ming Luoh; Goddard; Dorothea Reilly; William J. Henzel; Bass

January 1, 1996

Pulmonary and mediastinal metastases of a vaccination-site sarcoma in a cat

Veterinary Pathology, ISSN: 03009858

Daniel G. Rudmann; Van Alstine; Doddy; Sandusky; Barkdull; Evan B. Janovitz

January 1, 1996

Establishment of Schwann cell lines from normal adult and embryonic rat dorsal root ganglia

Journal of Neuroscience Methods, ISSN: 01650270

Li; Mark X. Sliwkowski; Jeannie Lo; Mather

January 1, 1996

'Knobs-into-holes' engineering of antibody C(H)3 domains for heavy chain heterodimerization

Protein Engineering, ISSN: 02692139

John B.B. Ridgway; Presta; Paul J. Carter

January 1, 1996

Liquid-liquid emulsification by static mixers for use in microencapsulation

Journal of Microencapsulation, ISSN: 02652048

Maa; Chung C. Hsu

January 1, 1996

Testicular germ cell populations in the adult rat after continuous in-vivo testicular infusion of inhibin-A and activin-A

International Journal of Andrology, ISSN: 01056263

Adeeko; Dunne; Mather; Alison Moore; Morris

January 1, 1996

Adaptation to ozone in rats and its association with ascorbic acid in the lung

Fundamental and Applied Toxicology, ISSN: 02720590

Wiester; Tepper; Winsett; Crissman; Richards; Costa

January 1, 1996

Genetic absence of γ-interferon delays but does not prevent diabetes in NOD mice

Diabetes, ISSN: 00121797

Hultgren; Huang; Noel Dybdal; Stewart

January 1, 1996

Establishment and characterization of a cytotrophoblast cell line from normal placenta of human origin

Human Reproduction, ISSN: 02681161

Li Rong-Hao; Shuyi Luo; Linzhi Zhuang

January 1, 1996

Age, education, and changes in the mini-mental state exam scores of older women: Findings from the Nun Study

Journal of the American Geriatrics Society, ISSN: 00028614

Steven M. Butler; J. Wesson Ashford; David A. Snowdon

January 1, 1996

Chiral kinetics and dynamics of ketorolac

Journal of Clinical Pharmacology, ISSN: 00912700

Edward Mroszczak; Daniel Combs; Melvin Chaplin; Irene Tsina; Thomas Tarnowski; Cynthia Rocha; Yuen Tam; Aileen Boyd; John Young; Linval Depass

January 1, 1996

Neuronal chain gangs: Homotypic contacts support migration into the olfactory bulb

Neuron, ISSN: 08966273

Nancy A. O'Rourke

January 1, 1996

Cell culture engineering.

Trends in Biotechnology, ISSN: 01677799

Robert Kiss

January 1, 1996

Oxidant generation and lung injury after particulate air pollutant exposure increase with the concentrations of associated metals

Inhalation Toxicology, ISSN: 08958378

Robert J. Pritchard; Andrew J. Ghio; James R. Lehmann; Winsett; Tepper; Patricia Park; M. Ian Gilmour; Kevin Dreher; Costa

January 1, 1996

The contribution of gene manipulation techniques to understanding dorsoventral patterning in the vertebrate nervous system

Seminars in Neuroscience, ISSN: 10445765

Mary Hynes; Rosenthal

January 1, 1996

Pharmacokinetics, tissue distribution, and expression Efficiency of plasmid [33P]DNA following intravenous administration of DNA/cationic lipid complexes in mice: Use of a novel radionuclide approach

Journal of Pharmaceutical Sciences, ISSN: 00223549

Gary Osaka; Kendall Carey; R. Andrew Cuthbertson; Godowski; Thomas W. Patapoff; Anne Ryan; Thomas Gadek; Joyce Mordenti

January 1, 1996

Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by intrastriatal 6-hydroxydopamine in the rat

Neuroscience, ISSN: 03064522

Lee; Hans Sauer; Anders Bjorklund

January 1, 1996

Ligand-induced assembly and activation of the gamma interferon receptor in intact cells

Molecular and Cellular Biology, ISSN: 02707306

Bach; William Tanner; Scot A. Marsters; Avi Ashkenazi; Michel Aguet; Andrey S. Shaw; Schreiber

January 1, 1996

Novel assays based on human growth hormone receptor as alternatives to the rat weight gain bioassay for recombinant human growth hormone

Biologicals, ISSN: 10451056

Roswall; Mukku; Chen; Hoff; Chu; McKay; Olson; John E. Battersby; Richard L. Gehant; Meunier; Robert L. Garnick

January 1, 1996

Utility of the National Cooperative Growth Study database for safety reporting

Journal of Pediatrics, ISSN: 00223476

David Graves

January 1, 1996

Translational level is a critical factor for the secretion of heterologous proteins in escherichia coli

Nature Biotechnology, ISSN: 15461696 10870156

Laura C. Simmons; Yansura

January 1, 1996

Developmental differences in the IGF-I system response to severe and chronic calorie malnutrition

American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849

Oster; Nancy Levin; Fielder; Icaf Robinson; Baxter; Cronin

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