Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13351 - 13400 OF 15572 RESULTS

Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon γ and tumor necrosis factor α
Journal of Experimental Medicine, ISSN: 15409538 00221007
Inge E. A. Flesch; Jürgen H. Hess; Sui Huang; Michel Aguet; Joachim Rothe; Horst Bluethmann; Stefan H. E. Kaufmann
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The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon γ in vivo
Journal of Experimental Medicine, ISSN: 15409538 00221007
Vicki M. Eng; Bruce D. Car; Bruno Schnyder; Meike Lorenz; Serena Lugli; Michel Aguet; Timothy D. Anderson; Bernhard Ryffel; Valerie F. J. Quesniaux
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The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Zhaohui Shao; Siegfried Ruppert; Paul D. Robbins
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A variant X-linked chronic granulomatous disease patient (X91+) with partially functional cytochrome b
Journal of Biological Chemistry, ISSN: 00219258
Andrew R. Cross; Heyworth; Julie Rae; John T. Curnutte
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Use of multifactorial analysis to develop aqueous two-phase systems for isolation of non-native IGF-I
Bioseparation, ISSN: 0923179X
Hart; John R. Ogez; Stuart E. Builder
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The duffy antigen/receptor for chemoklnes (DARC) is expressed in endothelial cells of duffy negative individuals who lack the erythrocyte receptor
Journal of Experimental Medicine, ISSN: 15409538 00221007
Stephen C. Peiper; Zi-Xuan Wang; Kuldeep Neote; Alvin W. Martin; Henry J. Showell; Maryrose J. Conklyn; Kevin Ogborne; Hadley; Zhao-Hai Lu; Joseph Hesselgesser; Richard Horuk
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Insulin-like growth factor-1 and growth hormone (GH) have distinct and overlapping anabolic effects in GH-deficient rats
Endocrine, ISSN: 0969711X 15590100
Ross Clark; Deborah L. Mortensen; Carlsson
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Proton NMR Assignments and Solution Conformation of RANTES, a Chemokine of the C-C Type
Biochemistry, ISSN: 15204995 00062960
Nicholas J. Skelton; Fernando Aspiras; John R. Ogez; J. Schall Thomas
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The cytosolic activating factors P47phox and p67phox have distinct roles in the regulation of electron flow in NADPH oxidase
Journal of Biological Chemistry, ISSN: 00219258
Andrew R. Cross; John T. Curnutte
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Molecular cloning of a ligand for the EPH-related receptor protein-tyrosine kinase Htk
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Brian D. Bennett; Francis C. Zeigler; Qimin Gu; Brian M. Fendly; Goddard; Nancy Gillett; William Matthews
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Mice from a genetically resistant background lacking the interferon γ receptor are susceptible to infection with leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response
Journal of Experimental Medicine, ISSN: 15409538 00221007
Kristin Swihart; Ulrich Fruth; Nathalie Messmer; Katharina Hug; Reza Behin; Sui Huang; Giuseppe Del Giudice; Michel Aguet; Jacques A. Louis
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Axon-induced mitogenesis of human Schwann cells involves heregulin and p185erbB2
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Thomas K. Morrissey; Allan D. O. Levi; Andrew Nuijens; Mark X. Sliwkowski; Richard P. Bunge
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The use of laser diffraction for the evaluation of the aerosol clouds generated by medical nebulizers
International Journal of Pharmaceutics, ISSN: 03785173
Clark
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Development of anti-p185HER2 immunoliposomes for cancer therapy
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Park; Hong; Paul J. Carter; Asgari; Guo; Gilbert-Andre Keller; Wirth; Shalaby; Claire Kotts; William I. Wood; Papahadjopoulos; Benz
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Characterization of the hormone binding site of natriuretic peptide receptor-C
FEBS Letters, ISSN: 00145793
Alfred M Engel; David G Lowe
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Development of a Humanized Disulfide-stabilized Anti-p185HER2 Fv-β-Lactamase Fusion Protein for Activation of a Cephalosporin Doxorubicin Prodrug
Cancer Research, ISSN: 15387445 00085472
Maria L. Rodrigues; Presta; Claire Kotts; Wirth; Joyce Mordenti; Gary Osaka; Wai Lee T. Wong; Andrew Nuijens; Brent Blackburn; Paul J. Carter
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Genomic structure, chromosomal localization, and conserved alternative splice forms of thrombopoietin
Blood, ISSN: 00064971
Austin L. Gurney; Wun-Jing Kuang; Xie; Malloy; Dan L. Eaton; Frederic J. De Sauvage
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Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus
Nature, ISSN: 00280836
Betty A. Maddux; Paolo Sbraccia; Shinobu Kumakura; Shlomo Sasson; Jack Youngren; Alexander Fisher; Steven A. Spencer; Andrew Grupe; William J. Henzel; Stewart; Gerald M. Reaven; Ira D. Goldfine
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Bispecific HER2 × CD3 Antibodies Enhance T-Cell Cytotoxicity in Vitro and Localize to HER2-Overexpressing Xenografts in Nude Mice
Clinical Immunology and Immunopathology, ISSN: 00901229
Shalaby; Paul J. Carter; Daniel A. Maneval; Giltinan; Claire Kotts
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Apoptosis in CHO cell batch cultures: examination by flow cytometry
Cytotechnology, ISSN: 09209069 15730778
Alison Moore; Christopher J. Donahue; Jeff Hooley; Diana L. Stocks; Kenneth D. Bauer; Mather
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Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: Identification of a novel in vivo role for p75
Journal of Experimental Medicine, ISSN: 15409538 00221007
Kathleen C. Sheehan; J. Keith Pinckard; Cora D. Arthur; Louis P. Dehner; David V. Goeddel; Schreiber
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Effects of growth hormone in rats with postinfarction left ventricular dysfunction
Cardiovascular Drugs and Therapy, ISSN: 09203206 15737241
Renhui Yang; Bunting; Nancy Gillett; Ross Clark; Hongkui Jin
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Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Diane Pennica; King; Kenneth J. Shaw; Luis; Janette Rullamas; Shiuh-Ming Luoh; Darbonne; Deborah S. Knutzon; Randy Yen; Kenneth R. Chien; Baker; William I. Wood
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Nerve growth factor levels in cultured human skin cells: effect of gestation and viral transformation
Neuroscience Letters, ISSN: 03043940
Anand; Foley; Navsaria; Sinicropi; Williams-Chestnut; Leigh
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Mesencephalic dopaminergic neurons protected by gdnf from axotomy-induced degeneration in the adult brain
Nature, ISSN: 00280836
Klaus D. Beck; Janet Valverde; Alexi; Kris Poulsen; Moffat; Richard L. Vandlen; Rosenthal; Franz Hefti
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Monoclonal antibodies that block the activity of leukocyte function-associated antigen 1 recognize three discrete epitopes in the inserted domain of CD11a
Journal of Biological Chemistry, ISSN: 00219258
Mark Champe; Bradley W. McIntyre; Berman
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Control of neuronal diversity by the floor plate: Contact-mediated induction of midbrain dopaminergic neurons
Cell, ISSN: 00928674
Mary Hynes; Kris Poulsen; Marc Tessier-Lavigne; Rosenthal
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Similar but nonidentical amino acid residues on vascular cell adhesion molecule-1 are involved in the interaction with α4β1 and α4β7 under different activity states
Journal of Immunology, ISSN: 00221767
Chiu; Crowe; Renz; Presta; Susan Jones; Irving L. Weissman; Fong
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Pharmacokinetics and pharmacodynamics of TP-9201, a GPIIbIIIa antagonist, in rats and dogs
Journal of Cardiovascular Pharmacology, ISSN: 15334023 01602446
Modi; Sharon A. Baughman; Paasch; Abbie Celniker; Susan Yvonne Smith
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Selective modulation of the expression of L-selectin ligands by an immune response
Current Biology, ISSN: 09609822
David Hoke; Mebius; Noel Dybdal; Dowbenko; Gribling; Carrie Kyle; Baumhueter; Susan R. Watson
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A P-selectin-immunoglobulin G chimera is protective in a rabbit ear model of ischemia-reperfusion
Surgery (United Kingdom), ISSN: 00396060
Wyne P. Lee; Gribling; Leo De Guzman; Niloofar Ehsani; Susan R. Watson
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From sticky zippers to morphology
Nature Structural Biology, ISSN: 10728368
Lasky
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Effect of Adjuvants on Immunogenicity of MN Recombinant Glycoprotein 120 in Guinea Pigs
AIDS Research and Human Retroviruses, ISSN: 19318405 08892229
Powell; Eastman; Lim; Catherine Lucas; Peterson; Vennari; Weissburg; Wrin; Kensil; Newman; Nunberg; Cleland; Timothy Gregory; Berman
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Human trks: Molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins
Journal of Neuroscience, ISSN: 02706474
David L. Shelton; Sutherland; Gripp; Camerato; Armanini; Phillips; Carroll; Spencer; Levinson
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Recognition of a 170 kD protein in mammalian Golgi complexes by an antibody against malarial intraerythrocytic lamellae
Tissue and Cell, ISSN: 00408166
Wenlu Li; Gilbert-Andre Keller; Kasturi Haldar
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Surface Denaturation at Solid-Void Interface—A Possible Pathway by Which Opalescent Participates Form During the Storage of Lyophilized Tissue-Type Plasminogen Activator at High Temperatures
Pharmaceutical Research, ISSN: 1573904X 07248741
Chung C. Hsu; Hoc M. Nguyen; Yeung; Brooks; Koe; Bewley; Rodney Pearlman
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Agonist selectivity for three species of natriuretic peptide receptor-A
Molecular Pharmacology, ISSN: 0026895X
Schoenfeld; Sehl; Quan; Burnier; David G Lowe
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Adjuvant effects on morphine-induced suppression of immune responses to MN RGP120/HIV-1 in mice
Advances in Experimental Medicine and Biology, ISSN: 00652598
Virsik; Bussiere
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Structural and functional epitopes in the growth hormone receptor complex: Can information from large molecules lead to the design of small molecule mimetics?
Bio/Technology, ISSN: 0733222X
James A. Wells
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Design and production of single-immunization vaccines using polylactide polyglycolide microsphere systems.
Chinese Journal of Pharmaceutical Biotechnology, ISSN: 10780467
Cleland
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Beneficial effects of growth hormone and insulin-like growth factor-1 in experimental heart failure in rats treated with chronic ACE inhibition
Journal of Cardiovascular Pharmacology, ISSN: 15334023 01602446
Hongkui Jin; Renhui Yang; Nancy Gillett; Ross Clark; Annie Ko; Nicholas F. Paoni
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Intravenous aspirin causes a paradoxical attenuation of cerebrovascular thrombolysis
Stroke, ISSN: 15244628 00392499
G. Roger Thomas; Harold Thibodeaux; Carol J. Errett; Martin M. Bednar; Cordell E. Gross; William F. Bennett
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Neurotrophin-4/5 enhances survival of cultured spiral ganglion neurons and protects them from cisplatin neurotoxicity
Journal of Neuroscience, ISSN: 02706474
Zheng; Randall R. Stewart; Gao
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Sialomucins in inflammation and hematopoiesis
Advances in Experimental Medicine and Biology, ISSN: 00652598
Lasky
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Chemokine binding and activities mediated by the mouse IL-8 receptor
Journal of Immunology, ISSN: 00221767
James Lee; Cacalano; Camerato; Toy; Mark Moore; William I. Wood
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Preclinical safety assessment considerations in vaccine development.
Chinese Journal of Pharmaceutical Biotechnology, ISSN: 10780467
Bussiere; McCormick; Green
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Pressor and bradykardie effects of centrally administered relaxin in conscious rats
American Journal of Hypertension, ISSN: 08957061
Renhui Yang; Bunting; Michael Wyss; Berecek; Zhang; Hongkui Jin
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Adaptation to persistent growth in the H9 cell line renders a primary isolate of human immunodeficiency virus type 1 sensitive to neutralization by vaccine sera
Journal of Virology, ISSN: 0022538X
Wrin; Tatjana P. Loh; Vennari; Hanneke Schuitemaker; Nunberg
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Selectin-carbohydrate interactions and the initiation of the inflammatory response
Annual Review of Biochemistry, ISSN: 00664154
Lasky
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Amino acids of the human growth hormone receptor that are required for proliferation and Jak-STAT signaling
Molecular Endocrinology, ISSN: 19449917 08888809
Wang; William I. Wood
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