Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13501 - 13550 OF 15217 RESULTS

Loss in expression of the retinoblastoma gene product in human gliomas is associated with advanced disease
Journal of Neuro-Oncology, ISSN: 0167594X 15737373
Wolfgang Hamel; Manfred Westphal; Shepard
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O-linked fucose and other post-translational modifications unique to EGF modules
Glycobiology, ISSN: 09596658
Reed J. Harris; Spellman
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Human macrophage inflammatory protein cr (MIP-1α) and MIP-1β chemoklnes attract distinct populations of lymphocytes
Journal of Experimental Medicine, ISSN: 15409538 00221007
Thomas J. Schall; Bacon; Camp; Kaspari; David V. Goeddel
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Theoretical considerations for the design and development of a drug: Influence of pharmacokinetics and dosage regimen on receptor interactions
Pharmaceutical Research, ISSN: 07248741
Joyce Mordenti; Rescigno
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Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor
Cell, ISSN: 00928674
Louis A. Tartaglia; Mike Rothe; Yan-Fen Hu; David V. Goeddel
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Solid phase synthesis of peptide para -nitroanilides
Tetrahedron Letters, ISSN: 00404039
Burdick; Martin Struble; Burnier
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Physical Properties of Recombinant Apolipoprotein(a) and Its Association with LDL to Form an Lp(a)-like Complex
Biochemistry, ISSN: 15204995 00062960
Martin L. Phillips; Audra V. Lembertas; Verne N. Schumaker; Lawn; Steven J. Shire; Zioncheck
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Protein sorting by high-performance liquid chromatography. I. Biomimetic interaction chromatography of recombinant human deoxyribonuclease I on polyionic stationary phases
Journal of Chromatography A, ISSN: 00219673
Cacia; Quan; Vasser; Mary B. Sliwkowski; John Frenz
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Proper glycosylation and phosphorylation of the type A natriuretic peptide receptor are required for hormone-stimulated guanylyl cyclase activity
Journal of Biological Chemistry, ISSN: 00219258
Koller; Michael T. Lipari; David V. Goeddel
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A new yeast gene with a myosin-like heptad repeat structure
Molecular and General Genetics, ISSN: 00268925 16174623
Ralf Kölling; Nguyen; Ellson Y. Chen; David Botstein
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Lack of impact of early catheterization and fibrin specificity on bleeding complications after thrombolytic therapy
Journal of the American College of Cardiology, ISSN: 07351097
Thomas C. Wall; Robert M. Califf; Stephen G. Ellis; Kristina Sigmon; Dean J. Kereiakes; Barry S. George; Joseph Samaha; David Sane; David Stump; Richard S. Stack; Eric Topol
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Biochemical Characterization of the Extracellular Domain of the 75-Kilodalton Tumor Necrosis Factor Receptor
Biochemistry, ISSN: 15204995 00062960
Diane Pennica; Van Lam; Weber; William J. Kohr; Basa; Spellman; Avi Ashkenazi; Steven J. Shire; David V. Goeddel
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An Alu sequence interupts a human 5-hydroxytryptamine1D receptor pseudogene
Gene, ISSN: 03781119
Tuan Nguyen; Adriano Marchese; James L. Kennedy; Arturas Petronis; Peroutka; Peter H. Wu; Brian F. O'Dowd
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X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling
Journal of Molecular Biology, ISSN: 00222836
Eigenbrot; Michael Randal; Presta; Paul J. Carter; Anthony A. Kossiakoff
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Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor
Cell, ISSN: 00928674
Kuldeep Neote; DiGregorio; John Mak; Richard Horuk; Thomas J. Schall
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Extracellular matrix regulates expression of the TGF-β1 gene
Journal of Cell Biology, ISSN: 00219525
Charles H. Streuli; Christian Schmidhauser; Michael S. Kobrin; Mina J. Bissell; Rik Derynck
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Appearance of additional ouabain binding sites on platelet surfaces following activation
Experimental Cell Research, ISSN: 00144827
Tracie Bork; Mrsny
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Comparative analysis of the human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells: Interacting effects involving suppression, synergistic suppression, and blocking of suppression
Journal of Immunology, ISSN: 00221767
Hal E. Broxmeyer; Barbara Sherry; Scott Cooper; Li Lu; Rodney Maze; M. Patricia Beckmann; Cerami; Peter Ralph
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Stability characterization and formulation development of alteplase, a recombinant tissue plasminogen activator.
Chinese Journal of Pharmaceutical Biotechnology, ISSN: 10780467
Tue H. Nguyen; Carole A. Ward
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Binding of L-selectin to the vascular sialomucin CD34
Science, ISSN: 00368075
Baumhueter; Mark S. Singer; William J. Henzel; Stefan Hemmerich; Renz; Steven D. Rosen; Lasky
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Humanization of an antibody directed against IgE
Journal of Immunology, ISSN: 00221767
Presta; Steven Lahr; Robert L. Shields; James P. Porter; Cornelia M. Gorman; Brian M. Fendly; Paula Jardieu
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Preparation of Radiolabeled Materials for Studies of Deposition of Fibers in the Human Respiratory Tract
Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 15579026 08942684
Chan; Gonda
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In situ ligand binding of recombinant human [125I] activin-A and recombinant human [125I]inhibin-A to the adult rat ovary
Endocrinology, ISSN: 19457170 00137227
Woodruff; Lynne Krummen; Glynis McCray; Mather
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Protective effects of selectin chimeras in neutrophil-mediated lung injury
Journal of Immunology, ISSN: 00221767
Michael S. Mulligan; Susan R. Watson; Christopher Fennie; Peter A. Ward
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The vascular endothelial growth factor (VEGF) isoforms: Differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF
Molecular Biology of the Cell, ISSN: 10591524
John E. Park; Gilbert-Andre Keller; Napoleone Ferrara
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Assessing genetic heterogeneity in production cell lines: Detection by peptide mapping of a low level tyr to gln sequence variant in a recombinant antibody
Nature Biotechnology, ISSN: 10870156
Reed J. Harris; Amy Murnane; Utter; Karen L. Wagner; Edward T. Cox; Gian D. Polastri; Helder; Mary B. Sliwkowski
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Intravenous and endobronchial administration of G4120, a cyclic Arg-Gly-Asp-containing platelet GPIIb/IIIa receptor-blocking pentapeptide, enhances and sustains coronary arterial thrombolysis with rt-PA in a canine preparation
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642
Tsunehiro Yasuda; Herman K. Gold; Chikashi Kohmura; Luis Guerrero; Hiroyuki Yaoita; John T. Fallon; Bunting; Desire Collen
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Stability and characterization of human growth hormone.
Chinese Journal of Pharmaceutical Biotechnology, ISSN: 10780467
Rodney Pearlman; Bewley
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Activated eosinophils evoke chloride secretion in model intestinal epithelia primarily via regulated release of 5'-AMP
Journal of Immunology, ISSN: 00221767
Murray B. Resnick; Sean P. Colgan; Thomas W. Patapoff; Mrsny; Christopher S. Awtrey; Charlene Delp-Archer; Peter F. Weller; James L. Madara
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Expression of insulin-like growth factor-I (IGF-I) in the rat fallopian tube: Possible autocrine and paracrine action of fallopian tube-derived IGF-I on the fallopian tube and on the preimplantation embryo
Endocrinology, ISSN: 19457170 00137227
Carlsson; Hillensjo; Anders Nilsson; Tornell; Billig
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Characterization of radioiodinated recombinant human TGF‐β1 binding to bone matrix within rabbit skull defects
Journal of Bone and Mineral Research, ISSN: 15234681 08840431
Richardson; Zioncheck; Edward P. Amentoè; Leo Deguzmanè; Wyne P. Leeè; Yvette Xuè; L. Steven Beckè
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Increased Transforming Growth Factor β Expression Inhibits Cell Proliferation in Vitro, yet Increases Tumorigenicity and Tumor Growth of Meth A Sarcoma Cells
Cancer Research, ISSN: 15387445 00085472
Hsun-Lang Chang; Nancy Gillett; Figari; Alfredo R. Lopez; Michael A. Palladino; Rik Derynck
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Protein engineering. Editorial overview
Current Opinion in Biotechnology, ISSN: 09581669
Anthony A. Kossiakoff; Michael Smith
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Partial functional mapping of the human interleukin-8 type A receptor: Identification of a major ligand binding domain
Journal of Biological Chemistry, ISSN: 00219258
Hébert; Anan Chuntharapai; Smith; Timothy J. Colby; Jin Kim; Richard Horuk
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Glycosylation-dependent cell adhesion molecule 1 (GlyCAM 1) mucin is expressed by lactating mammary gland epithelial cells and is present in milk
Journal of Clinical Investigation, ISSN: 00219738
Dowbenko; Kikuta; Christopher Fennie; Nancy Gillett; Lasky
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Growth factor modulation of insulin-like growth factor-binding proteins in rat osteoblast-like cells
Endocrinology, ISSN: 19457170 00137227
Theresa L. Chen; Chang; DiGregorio; Andrew J. Perlman; Yung-Fu Huang
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Human relaxin decreases collagen accumulation in vivo in two rodent models of fibrosis
Journal of Investigative Dermatology, ISSN: 15231747 0022202X
Elaine N. Unemori; Steven Beck; Wyne P. Lee; Yvette Xu; Mark Siegel; Gilbert-Andre Keller; Liggitt; Eugene A. Bauer; Edward P. Amento
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Synergistic effect of interleukin‐1β and tumor necrosis factor α on interleukin‐8 gene expression in synovial fibroblasts. evidence that interleukin‐8 is the major neutrophil‐activating chemokine released in response to monokine activation
Arthritis and Rheumatism, ISSN: 15290131 00043591
Palaniswami Rathanaswami; Mohamed Hachicha; Wai Lee T. Wong; Thomas J. Schall; Shaun R. McColl
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Electrospray ionization mass spectrometry of phosphopeptides isolated by on-line immobilized metal-ion affinity chromatography
Journal of the American Society for Mass Spectrometry, ISSN: 18791123 10440305
Lydia M. Nuwaysir; Stults
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A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. I. Serum growth hormone-binding protein
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Paul M. Martha Jr.; Alan D. Rogol; Carlsson; Gesundheit; Robert M. Blizzard
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Activin induces cell death in hepatocytes in vivo and in vitro
Hepatology, ISSN: 15273350 02709139
Ralph H. Schwall; Robbins; Paula Jardieu; Chang; Cora La; Timothy G. Terrel
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Insulin-like growth factor-1 stimulation of lymphopoiesis
Journal of Clinical Investigation, ISSN: 00219738
Ross Clark; Josef Stresser; McCabe; Kimberly Bobbins; Paula Jardieu
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Analysis of 24-hour plasma profiles of growth hormone (GH)-binding protein, GH/GH-binding protein-complex, and GH in healthy children
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Carlsson; Sten Rosberg; Roderick V. Vitangcol; Wai Lee T. Wong; Kerstin Albertsson-Wikland
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Developmental expression of binding sites and messenger ribonucleic acid for vascular endothelial growth factor suggests a role for this protein in vasculogenesis and angiogenesis
Endocrinology, ISSN: 19457170 00137227
Lyn B. Jakeman; Armanini; Phillips; Napoleone Ferrara
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Studies on the mechanisms by which transforming growth factor-β (TGF-β) protects against allergic encephalomyelitis: Antagonism between TGF-β and tumor necrosis factor
Journal of Immunology, ISSN: 00221767
Laura Santambrogio; Gerald M. Hochwald; Babita Saxena; Chin-Hung Leu; Joseph E. Martz; Joseph A. Carlino; Nancy Ruddle; Michael A. Palladino; Leslie I. Gold; Thorbecke
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Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice
Journal of Clinical Investigation, ISSN: 00219738
Jawaid Quddus; Kent J. Johnson; Jerrie Gavalchin; Edward P. Amento; Clarence E. Chrisp; Raymond L. Yung; Bruce C. Richardson
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The Application of size exclusion chromatography and computer simulation to study the thermodynamic and kinetic parameters for short-lived dissociable protein aggregates
Analytical Biochemistry, ISSN: 10960309 00032697
Thomas W. Patapoff; Mrsny; William A. Lee
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Human recombinant activin-A alters pituitary luteinizing hormone and follicle-stimulating hormone secretion, follicular development, and steroidogenesis, during the menstrual cycle in rhesus monkeys
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Richard L. Stouffer; Woodruff; Dahl; David L. Hess; Mather; Theodore A. Molskness
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Structure and function of human growth hormone: Implications for the hematopoietins
Annual Review of Biophysics and Biomolecular Structure, ISSN: 10568700
James A. Wells; De Vos
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Hypothalamic infusion of activin A increases water consumption and urine volume in the rat
Neuroendocrinology, ISSN: 00283835
Ralph H. Schwall; Lyn B. Jakeman; C.Anthony Altar
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