Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13551 - 13600 OF 15217 RESULTS

Benzodiazepine peptidomimetics: Potent inhibitors of Ras farnesylation in animal cells
Science, ISSN: 00368075
Guy L. James; Joseph L. Goldstein; Michael S. Brown; Thomas E. Rawson; Todd C. Somers; Robert S. McDowell; Crowley; Brian K. Lucas; Levinson; James C. Marsters Jr.
View on Scopus
Mutational analysis of the intracellular domain of the human growth hormone receptor
Journal of Biological Chemistry, ISSN: 00219258
Colosi; Wong; Leong; William I. Wood
View on Scopus
A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor β, or bone morphogenic factor
Journal of Biological Chemistry, ISSN: 00219258
Koichi Matsuzaki; Jian M. Xu; Fen Wang; Wallace L. McKeehan; Lynne Krummen; Mikio Kan
View on Scopus
Follistatin modulates activin activity in a cell and tissue-specific manner
Endocrinology, ISSN: 19457170 00137227
Mather; Penelope E. Roberts; Lynne Krummen
View on Scopus
Characterization of neurotrophin receptors by affinity crosslinking
Journal of Neuroscience Research, ISSN: 10974547 03604012
Escandon; Louis E. Burton; Szonyi; Nikolics
View on Scopus
The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells
Neuron, ISSN: 08966273
Tsoulfas; Soppet; Escandon; Lino Tessarollo; José-Luis Mendoza-Ramírez; Rosenthal; Nikolics; Parada
View on Scopus
Genetic stability and recombinant product consistency
Biologicals, ISSN: 10958320 10451056
Burstyn; Copmann; Dinowitz; Robert L. Garnick; Losikoff; Lubiniecki; Wiebe
View on Scopus
Recombinant human inhibin a and recombinant human activin a regulate pituitary and ovarian function in the adult female rat
Endocrinology, ISSN: 19457170 00137227
Woodruff; Lynne Krummen; Lyon; Diana L. Stocks; Mather
View on Scopus
A system approach to pharmacodynamics. Input‐effect control system analysis of central nervous system effect of alfentanil
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Veng-Pedersen; Modi
View on Scopus
A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans
Journal of Clinical Investigation, ISSN: 00219738
Mark L. Hartman; Peter E. Clayton; Michael L. Johnson; Abbie Celniker; Andrew J. Perlman; Alberti; Michael O. Thorner
View on Scopus
Growth hormone insensitivity associated with elevated circulating growth hormone-binding protein in children with Alagille syndrome and short stature
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
John C. Bucuvalas; Jo Ann Horn; Carlsson; William F. Balistreri; Chernausek
View on Scopus
TGF‐β1 induces bone closure of skull defects: Temporal dynamics of bone formation in defects exposed to rhTGF‐β1
Journal of Bone and Mineral Research, ISSN: 15234681 08840431
L. Steven Beck; Edward P. Amento; Yvette Xu; Leo Deguzman; Wyne P. Lee; Tue H. Nguyen; Nancy Gillett
View on Scopus
Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor
Science, ISSN: 00368075
Reinhard Ebner; Ruey-Hwa Chen; Lillian Shum; Sean Lawler; Zioncheck; Angela Lee; Alfredo R. Lopez; Rik Derynck
View on Scopus
Neurotrophins promote motor neuron survival and are present in embryonic limb bud
Nature, ISSN: 00280836
Christopher E. Henderson; William Camu; Clément Mettling; Annie Gouin; Kris Poulsen; Karihaloo; Janette Ruilamas; Tony Evans; McMahon; Armanini; Lucy R. Berkemeier; Phillips; Rosenthal
View on Scopus
Uncoupling of early signal transduction events from effector function in human peripheral blood neutrophils in response to recombinant macrophage inflammatory proteins-1α and -1β
Journal of Immunology, ISSN: 00221767
Shaun R. McColl; Mohamed Hachicha; Sylvain Levasseur; Kuldeep Neote; Thomas J. Schall
View on Scopus
Development of a specific and sensitive two-site enzyme-linked immunosorbent assay for measurement of inhibin-a in serum
Endocrinology, ISSN: 19457170 00137227
David E. Allison; Lynne Krummen; Teresa K. Woodruff; Chen; Brian M. Fendly; Bald; Mather; Catherine Lucas
View on Scopus
5′-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers
Journal of Clinical Investigation, ISSN: 00219738
James L. Madara; Thomas W. Patapoff; Beth Gillece-Castro; Sean P. Colgan; Charles A. Parkos; Charlene Delp; Mrsny
View on Scopus
Growth hormone-binding protein determination in plasma: A comparison of immunofunctional and growth hormone-binding assays
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Moises Mercado; Carlsson; Roderick V. Vitangcol; Gerhard Baumann
View on Scopus
A Truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells
Molecular and Cellular Biology, ISSN: 02707306
Gary K. Scott; Robert Robles; Park; Pamela A. Montgomery; Janice Daniel; William E. Holmes; James Lee; Gilbert-Andre Keller; Wenlu Li; Brian M. Fendly; William I. Wood; Shepard; Benz
View on Scopus
Recombinant human transforming growth factor β1 modulates bone remodeling in a mineralizing bone organ culture
Journal of Bone and Mineral Research, ISSN: 15234681 08840431
Theresa L. Chen; Rebecca L. Bates
View on Scopus
Differential effects of transforming growth factor‐β1 and bone morphogenetic protein 4 on gene expression and differentiated function of preosteoblasts
Journal of Cellular Physiology, ISSN: 10974652 00219541
Hong Zhou; R. Glenn Hammonds; David M. Findlay; Martin; Ng
View on Scopus
Multiple defects of immune cell function in mice with disrupted interferon-γ genes
Science, ISSN: 00368075
Dyana K. Dalton; Sharon Pitts-Meek; Satish Keshav; Figari; Allan Bradley; Stewart
View on Scopus
Mechanism-based design of prolactin receptor antagonists
Journal of Biological Chemistry, ISSN: 00219258
Fuh; Colosi; William I. Wood; James A. Wells
View on Scopus
Expression of the cytokine RANTES in human rheumatoid synovial fibroblasts. Differential regulation of RANTES and interleukin-8 genes by inflammatory cytokines
Journal of Biological Chemistry, ISSN: 00219258
Palaniswami Rathanaswami; Mohamed Hachicha; Michael D Sadick; Thomas J. Schall; Shaun R. McColl
View on Scopus
Regulation of neutrophil interleukin 8 gene expression and protein secretion by LPS, TNF‐α, and IL‐1β
Journal of Cellular Physiology, ISSN: 10974652 00219541
Seitaro Fujishima; Andrew R. Hoffman; Thanh Vu; K.Jin Kim; Hui Zheng; David Daniel; Youngmee Kim; Ellen F. Wallace; James W. Larrick; Thomas A. Raffin
View on Scopus
Factors predicting the response to growth hormone (GH) therapy in prepubertal children with GH deficiency
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Sandra L. Blethen; Peter G. Compton; Barbara M. Lippe; Rosenfeld; Gilbert P. August; Ann J. Johanson
View on Scopus
P- and E-selectin use common sites for carbohydrate ligand recognition and cell adhesion
Journal of Cell Biology, ISSN: 00219525
David V. Erbe; Susan R. Watson; Presta; Barry A. Wolitzky; Carroll Foxall; Brian K. Brandley; Lasky
View on Scopus
Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectin
Nature, ISSN: 00280836
Yasuyuki Imai; Lasky; Steven D. Rosen
View on Scopus
Neurotrophin gene expression by cell lines derived from human gliomas
Journal of Neuroscience Research, ISSN: 10974547 03604012
Wolfgang Hamel; Manfred Westphal; Szonyi; Escandon; Nikolics
View on Scopus
Pharmacokinetic profile of recombinant human (Rh) inhibin a and activin a in the immature rat. i. serum profile of rh-inhibin a and rh-activin a in the immature female rat
Endocrinology, ISSN: 19457170 00137227
Woodruff; Lynne Krummen; Chen; Geralyn G. Deguzman; Lyon; Deborah L. Baly; David E. Allison; Shaily Garg; Wai Lee T. Wong; Nora Hebert; Mather; Cossum
View on Scopus
Pharmacokinetic profile of recombinant human (Rh) inhibin a and activin a in the immature rat. ii. tissue distribution of [125i]rh-inhibin a and [125i]rh-activin a in immature female and male rats
Endocrinology, ISSN: 19457170 00137227
Woodruff; Lynne Krummen; Chen; Lyon; Hansen; Geralyn G. Deguzman; Covello; Mather; Cossum
View on Scopus
Analysis of repeated measurement data using the nonlinear mixed effects model
Chemometrics and Intelligent Laboratory Systems, ISSN: 01697439
Davidian; Giltinan
View on Scopus
Effects of G4120, a Arg-Gly-Asp containing synthetic platelet glycoprotein IIB/IIIA receptor antagonist, on arterial and venous thrombolysis with recombinant tissue-type plasminogen activator in dogs
Fibrinolysis and Proteolysis, ISSN: 02689499
Rapold; Herman K. Gold; Wu; Napier; Bunting; Desire Collen
View on Scopus
Evidence for a rebound coagulation phenomenon after cessation of a 4-hour infusion of a specific thrombin inhibitor in patients with unstable angina pectoris
Journal of the American College of Cardiology, ISSN: 07351097
Herman K. Gold; Frank W. Torres; Harry D. Garabedian; Wendy Werner; Ik-Kyung Jang; Agha Khan; J.Nathan Hagstrom; Tsunehiro Yasuda; Robert C. Leinbach; John B. Newell; Edwin G. Bovill; David Stump; Desire Collen
View on Scopus
The purely chronotropic effects of relaxin in the rat isolated heart
Journal of Pharmacy and Pharmacology, ISSN: 20427158 00223573
G. Roger Thomas; Richard L. Vandlen
View on Scopus
Use of Single Photon Emission Computed Tomography in Aerosol Studies
Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 15579026 08942684
Chan
View on Scopus
Evidence supporting a role for cathepsin B in the generation of T cell antigenic epitopes of human growth hormone
Molecular Immunology, ISSN: 01615890
Gillian Bushell; Nelson; Chiu; Christopher Grimley; William J. Henzel; Burnier; Sherman Fong
View on Scopus
Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometriosis
American Journal of Obstetrics and Gynecology, ISSN: 00029378
Omid Khorram; Robert N. Taylor; Isabelle P. Ryan; Thomas J. Schall; Daniel V. Landers
View on Scopus
Comparative Pathology of Recombinant Murine Interferon-γ in Mice and Recombinant Human Interferon-γ in Cynomolgus Monkeys
International Review of Experimental Pathology, ISSN: 00747718
Timothy G. Terrell; Green
View on Scopus
Analysis of polypeptides and proteins
Advanced Drug Delivery Reviews, ISSN: 0169409X
Andrew J.S. Jones
View on Scopus
Regulation of insulin-like growth factor binding protein production by human luteinizing granulosa cells cultured in defined medium
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Nicholas A. Cataldo; Woodruff; Linda C. Giudice
View on Scopus
Identification and characterization of binding proteins for inhibin and activin in human serum and follicular fluids
Endocrinology, ISSN: 19457170 00137227
Lynne Krummen; Woodruff; Geralyn G. Deguzman; Edward T. Cox; Deborah L. Baly; Elizabeth Mann; Shaily Garg; Wai Lee T. Wong; Cossum; Mather
View on Scopus
Hormonal induction of low affinity receptor guanylyl cyclase
EMBO Journal, ISSN: 02614189
Jewett; Koller; David V. Goeddel; David G Lowe
View on Scopus
Generation and characterization of a competitive antagonist of human hepatocyte growth factor, HGF/NK1
Journal of Biological Chemistry, ISSN: 00219258
Lokker; Godowski
View on Scopus
The Pharmacokinetics and Absorption of Recombinant Human Relaxin in Nonpregnant Rabbits and Rhesus Monkeys After Intravenous and Intravaginal Administration
Pharmaceutical Research, ISSN: 1573904X 07248741
Chen; Baron R. Reed; Tue H. Nguyen; Gaylord; Fuller; Joyce Mordenti
View on Scopus
The Pharmacokinetics of Recombinant Human Relaxin in Nonpregnant Women After Intravenous, Intravaginal, and Intracervical Administration
Pharmaceutical Research, ISSN: 1573904X 07248741
Chen; Andrew J. Perlman; Spanski; Peterson; Sanders; Robert B. Jaffe; Martin; Yalcinkaya; Cefalo; Chescheir; Menard; Joyce Mordenti
View on Scopus
Some general estimation methods for nonlinear mixed-effects models
Journal of Biopharmaceutical Statistics, ISSN: 15205711 10543406
Davidian; Giltinan
View on Scopus
Recombinant porcine prorelaxin produced in Chinese hamster ovary cells is biologically active
Life Sciences, ISSN: 00243205
Ann L. Vu; Carla B. Green; Katherine F. Roby; Michael J. Soares; David T.W. Fei; Chen; Simon C.M. Kwok
View on Scopus
Identification of a promiscuous inflammatory peptide receptor on the surface of red blood cells
Journal of Biological Chemistry, ISSN: 00219258
Kuldeep Neote; Darbonne; John R. Ogez; Richard Horuk; Thomas J. Schall
View on Scopus
Ligand passing: The 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor
Journal of Biological Chemistry, ISSN: 00219258
Louis A. Tartaglia; Diane Pennica; David V. Goeddel
View on Scopus
© 2024 Genentech, Inc. All rights reserved. This site is intended for US residents only.