Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13601 - 13650 OF 15217 RESULTS

January 1, 1993

Recombinant human insulin-like growth factor binding protein-3 (rhIGFBP-3): Effects on the glycemic and growth promoting activities of rhIGF-1 in the rat

Growth Regulation, ISSN: 0956523X

Ross Clark; Deborah L. Mortensen; Reifsynder; Mohler; Etcheverry; Mukku

January 1, 1993

In Vitro Evaluation of Dexamethasone-β-D-Glucuronide for Colon-Specific Drug Delivery

Pharmaceutical Research, ISSN: 1573904X 07248741

Barbara Haeberlin; Rubas; Harold W. Nolen III; David R. Friend

January 1, 1993

Assignment of heregulin (HGL) to human chromosome 8p22-p11 by PCR analysis of somatic cell hybrid DNA

Genomics, ISSN: 08887543

James Lee; William I. Wood

January 1, 1993

Peptide Stability in Drug Development. II. Effect of Single Amino Acid Substitution and Glycosylation on Peptide Reactivity in Human Serum

Pharmaceutical Research, ISSN: 1573904X 07248741

Powell; Tracy Stewart; Laszlo Jr Otvos; Urge; Federico C. A. Gaeta; Alessandro Sette; Arrhenius; David Thoon; Ken Soda; Colon

January 1, 1993

Two FIA-based biosensor systems studied for bioprocess monitoring

Journal of Biotechnology, ISSN: 01681656

Scheper; Brandes; Hans E. Maschke; Plötz; Müller

January 1, 1993

RGD-containing peptides inhibit adhesion of 293 cells transfected with GpIIb/IIIa to fibrinogen: Comparison to inhibition of platelet aggregation

Blood Coagulation and Fibrinolysis, ISSN: 09575235

David T.W. Fei; John Lowe; Bodary; Bunting; McLean; Napier; Chen

January 1, 1993

Induction of somatostatin immunoreactivity in cultured ciliary ganglion neurons by activin in choroid cell-conditioned medium

Neuron, ISSN: 08966273

James N. Coulombe; Ralph H. Schwall; Annette S. Parent; Felix P. Eckenstein; Rae Nishi

January 1, 1993

A truncated erythropoietin receptor and cell death

Science, ISSN: 00368075

Schwall; Nakamura; Nakauchi

January 1, 1993

Growth response of children with non-growth-hormone deficiency and marked short stature during three years of growth hormone therapy

Journal of Pediatrics, ISSN: 00223476

Hopwood; Hintz; Gertner; Kenneth M. Attie; Ann J. Johanson; Joyce Baptista; Joyce Kuntze; Robert M. Blizzard; Cara; Chernausek; Selna L. Kaplan; Barbara M. Lippe; Plotnick; Saenger

January 1, 1993

Binding interactions of kistrin with platelet glycoprotein IIb‐IIIa: Analysis by site‐directed mutagenesis

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Dennis; Paul J. Carter; Lazarus

January 1, 1993

Investigation of the processing of GLP-1(7-36)amide by membrane peptidases

Digestion, ISSN: 14219867 00122823

Gerard Patrick McGregor; Karin Hupe-Sodmann; Robert L. Bridenbaugh; Bodo Zimmermann; Hubert Thole; Burkhard Göke; Rüdiger Göke; Karlheinz Voigt

January 1, 1993

A slow clearing, Fibrin-Specific, PAI-1 resistant variant of t-PA (T103N, KHRR 296-299 AAAA)

Thrombosis and Haemostasis, ISSN: 03406245

Nicholas F. Paoni; Key; Refino; Alice M. Chow; Hung V. Nguyen; Lea Berleau; Julie M. Badillo; Luis Peña; Brady; Florian M. Wurm; John R. Ogez; William F. Bennett

January 1, 1993

An evaluation of mechanisms by which tolerance to organ-specific antigens is lost using a transgenic mouse model

Journal of Immunology, ISSN: 00221767

Martin; Mora-Worms; Catherine Lucas; Reynolds; Stewart

January 1, 1993

Functions of agrin and agrin-related proteins

Trends in Neurosciences, ISSN: 01662236

László Patthy; Nikolics

January 1, 1993

Structure-function studies of the t-PA molecule

Fibrinolysis and Proteolysis, ISSN: 02689499

William F. Bennett

January 1, 1993

Ultrasensitive plasmid mapping by high performance capillary electrophoresis

Electrophoresis, ISSN: 15222683 01730835

Hans E. Maschke; John Frenz; Belenkii; Karger; William S. Hancock

January 1, 1993

Separation of 21‐(R)‐ and 21‐(S)‐argatroban: Solubility and activity of the individual diastereoisomers

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Thomas E. Rawson; Kimmie VanGorp; Yang; Timothy P. Kogan

January 1, 1993

Is rheumatoid arthritis driven by oligoclonal T cells?

Clinical and Experimental Rheumatology, ISSN: 0392856X

Edward P. Amento

January 1, 1993

Tissue-engineered, three-dimensional human dermis to study extracellular matrix formation in wound healing

Cutaneous and Ocular Toxicology, ISSN: 15569527

Francis C. Zeigler; Lee Landeen; Gail K. Naughton; Sandra R. Slivka

January 1, 1993

A 'roll' in acute inflammation

Current Biology, ISSN: 09609822

Lasky

January 1, 1993

Regulation of the response to bacterial lipopolysaccharide by endogenous and exogenous lipopolysaccharide binding proteins

Blood Purification, ISSN: 14219735 02535068

Marra; Michael B. Thornton; James L. Snable; Leong; John C. Lane; Craig G. Wilde; Scott

January 1, 1993

Interventions for the Treatment of Septic Shock

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Figari; Michael A. Palladino

January 1, 1993

Expression of vascular endothelial growth factor does not promote transformation but confers a growth advantage in vivo to Chinese hamster ovary cells

Journal of Clinical Investigation, ISSN: 00219738

Napoleone Ferrara; Jane Winer; Theresa Burton; Rowland; Mark Siegel; Phillips; Timothy G. Terrell; Gilbert-Andre Keller; Levinson

January 1, 1993

Determination of peptide 520 in human plasma using post-column photolysis with electrochemical detection in liquid chromatography

Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085

Chen; Mazzeo; Krull; Wu

January 1, 1993

A variant of t-PA (T103N, KHRR 296-299 AAAA) that, by bolus, has increased potency and decreased systemic activation of plasminogen

Thrombosis and Haemostasis, ISSN: 03406245

Refino; Nicholas F. Paoni; Keyt; Cheryl Pater; Julie M. Badillo; Florian M. Wurm; John R. Ogez; William F. Bennett

January 1, 1993

One systemic administration of transforming growth factor-β1 reverses age- or glucocorticoid-impaired wound healing

Journal of Clinical Investigation, ISSN: 00219738

L. Steven Beck; Leo Deguzman; Wyne P. Lee; Yvette Xu; Mark Siegel; Edward P. Amento

January 1, 1993

Pathology of Recombinant Human Transforming Growth Factor-β1 in Rats and Rabbits

International Review of Experimental Pathology, ISSN: 00747718

Timothy G. Terrell; Peter K. Working; Chow; Green

January 1, 1993

Cloning of a rat homologue of mouse GlyCAM 1 reveals conservation of structural domains

Journal of Biological Chemistry, ISSN: 00219258

Dowbenko; Susan R. Watson; Lasky

January 1, 1993

Immunoadhesins

International Reviews of Immunology, ISSN: 08830185

Avi Ashkenazi; Capon; Ward

January 1, 1993

Leukemia inhibitory factor expression in human carotid plaques: Possible mechanism for inhibition of large vessel endothelial regrowth

Growth Factors, ISSN: 08977194

Nancy Gillett; David G Lowe; Lucy Lu; Curtis Chan; Napoleone Ferrara

January 1, 1993

Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo

Neuron, ISSN: 08966273

Vassilis E. Koliatsos; Richard E. Clatterbuck; Winslow; Michelle H. Cayouette; Donald L. Price

January 1, 1993

Induction of type I diabetes by interferon-α in transgenic mice

Science, ISSN: 00368075

Stewart; Hultgren; Huang; Sharon Pitts-Meek; James R. Hully; MacLachlan

January 1, 1993

A receptor for the malarial parasite Plasmodium vivax: The erythrocyte chemokine receptor

Science, ISSN: 00368075

Richard Horuk; Chitnis; Darbonne; Timothy J. Colby; Rybicki; Hadley; Miller

January 1, 1993

sICAM-1 enhances cytokine production stimulated by alloantigen

Cellular Immunology, ISSN: 00088749

McCabe; Riddle; Nakamura; Prashad; Mehta; Berman; Paula Jardieu

January 1, 1993

Pathogenetic mechanisms in cystic fibrosis lung disease: A paradigm for inflammatory airways disease

Journal of Laboratory and Clinical Medicine, ISSN: 00222143

Robert B. Fick Jr.

January 1, 1993

Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

William J. Henzel; Todd M. Billeci; Stults; Susan C. Wong; Christopher Grimley; Colin K. Watanabe

January 1, 1993

Transcriptional regulation of mammary tumor virus gene expression

Seminars in Virology, ISSN: 10445773

Godowski

January 1, 1993

Consensus review of the clinical utility of dna flow cytometry in colorectal cancer

Communications in Clinical Cytometry, ISSN: 10970320 01964763

Kenneth D. Bauer; Bagwell; Giaretti; Melamed; Zarbo; Witzig; Rabinovitch

January 1, 1993

Ling zhi-8: A novel t cell mitogen induces cytokine production and upregulation of ICAM-1 expression

Cellular Immunology, ISSN: 10902163 00088749

Haak-Frendscho; Kino; Toshio Sone; Paula Jardieu

January 1, 1993

The use of peptide mapping for the detection of heterogeneity in recombinant DNA-derived proteins

Biologicals, ISSN: 10451056

O'Connor

January 1, 1993

Optimized thrombolysis of cerebral clots with tissue-type plasminogen activator in a rabbit model of embolic stroke

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565

G. Roger Thomas; Harold Thibodeaux; William F. Bennett; Refino; Julie M. Badillo; Carol J. Errett; Justin A. Zivin

January 1, 1993

Expression of relaxin mRNA and relaxin receptors in postnatal and adult rat brains and hearts. Localization and developmental patterns

Journal of Biological Chemistry, ISSN: 00219258

Phyllis L. Osheroff; Ho

January 1, 1993

Stimulation of human T-cell proliferation by specific activation of the 75-kDa tumor necrosis factor receptor

Journal of Immunology, ISSN: 00221767

Louis A. Tartaglia; David V. Goeddel; Reynolds; Figari; Weber; Brian M. Fendly; Michael A. Palladino

January 1, 1993

The Kinetics of Relaxin Oxidation by Hydrogen Peroxide

Pharmaceutical Research, ISSN: 1573904X 07248741

Tue H. Nguyen; Burnier; Meng

January 1, 1993

Failure of intravenous pentamidine prophylaxis for Pneumocystis carinii pneumonia

Journal of Pediatrics, ISSN: 00223476

Peggy S. Weintrub; Diane W. Wara; A-M. Duliege

January 1, 1993

Chromosomes 8,12, and 17 Copy Number in Astler-Coller Stage C Colon Cancer in Relation to Proliferative Activity and DNA Ploidy

Cancer Research, ISSN: 15387445 00085472

Steiner; Harlow; Colombo; Kenneth D. Bauer

January 1, 1993

Processing and characterization of human proguanylin expressed in Escherichia coli

Journal of Biological Chemistry, ISSN: 00219258

Garcia; Frederic J. De Sauvage; Martin Struble; William J. Henzel; Dorothea Reilly; David V. Goeddel

January 1, 1993

Biosynthesis and function of membrane bound and secreted forms of recombinant CD11b/CD18 (Mac‐1)

Journal of Cellular Biochemistry, ISSN: 10974644 07302312

Berman; Nakamura; Riddle; Chiu; Karen L. Fisher; Mark Champe; Gray; Ward; Sherman Fong

January 1, 1993

Glycosylation Pattern and Disulfide Assignments of Recombinant Human Differentiation-Stimulating Factor

Archives of Biochemistry and Biophysics, ISSN: 00039861

Charles H. Schmelzer; Reed J. Harris; Daniel Butler; Yedinak; Karen L. Wagner; Louis E. Burton

January 1, 1993

Structure and chromosomal localization of the murine gene encoding GLYCAM 1. A mucin-like endothelial ligand for L Selectin

Journal of Biological Chemistry, ISSN: 00219258

Dowbenko; Andalibi; Paul Young; Aldons J. Lusis; Lasky

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