Genentech: Publications

May 1, 1992

A polymorphic dinucleotide repeat in intron 1 of the human tissue plasminogen activator gene

Human Molecular Genetics, ISSN: 09646906

Thomas; Drayna

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May 1, 1992

Purification and characterization of recombinant porcine prorelaxin expressed in Escherichia coli

Archives of Biochemistry and Biophysics, ISSN: 10960384 00039861

G.Kesava Reddy; Sripad Gunwar; Carla B. Green; David T.W. Fei; Chen; Simon C.M. Kwok

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April 30, 1992

Tumor necrosis factor-α pretreatment is protective in a rat model of myocardial ischemia-reperfusion injury

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Lynne J. Eddy; David V. Goeddel; Grace H.W. Wong

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April 24, 1992

Nerve growth factor increases calcium binding protein (Calbindin-D28K) in rat olfactory bulb

Brain Research, ISSN: 00068993

Iacopino; Christakos; Modi; C.Anthony Altar

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April 8, 1992

Recombinant Human DNase Inhalation in Normal Subjects and Patients With Cystic Fibrosis: A Phase 1 Study

JAMA - Journal of the American Medical Association, ISSN: 15383598 00987484

Moira L. Aitken; Wylie Burke; Gwen McDonald; Shak; A. Bruce Montgomery; Arnold L. Smith

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April 1, 1992

Differentiation factor/leukemia inhibitory factor protection against lethal endotoxemia in mice: Synergistic effect with interleukin 1 and tumor necrosis factor

Journal of Experimental Medicine, ISSN: 15409538 00221007

Richard Alexander; Grace H.W. Wong; Gerard M. Doherty; David J. Venzon; Douglas L. Fraker; Jeffrey A. Norton

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March 19, 1992

A preliminary study of aerosolized recombinant human deoxyribonuclease i in the treatment of cystic fibrosis

New England Journal of Medicine, ISSN: 15334406 00284793

Richard C. Hubbard; McElvaney; Birrer; Woodrow W. Robinson; Clara Jolley; Ronald G. Crystal; Shak; Margaret Wu; Milica S. Chernick

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March 6, 1992

Computer simulation as a tool for the rapid optimization of the high-performance liquid chromatogrpahic separation of a tryptic digest human growth hormone

Journal of Chromatography A, ISSN: 00219673

Chloupek; William S. Hancock; Lloyd R. Snyder

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March 1, 1992

Analysis of solvent structure in proteins using neutron D2OH2O solvent maps: Pattern of primary and secondary hydration of trypsin

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Anthony A. Kossiakoff; Sintchak; Shpungin; Presta

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February 14, 1992

Identity of a differentiation inhibiting factor for mouse myeloid leukemia cells with NM23/nucleoside diphosphate kinase

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Junko Okabe-Kado; Takashi Kasukabe; Yoshio Honma; Moriaki Hayashi; William J. Henzel; Hozumi

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February 5, 1992

The structure of human lymphotoxin (tumor necrosis factor-β) at 1.9-Å resolution

Journal of Biological Chemistry, ISSN: 00219258

Michael J. Eckt; Ultsch; Rinderknecht; De Vos; Stephen R. Sprang

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February 1, 1992

A Region of Tissue Plasminogen Activator That Affects Plasminogen Activation Differentially with Various Fibrin(ogen)-Related Stimulators

Biochemistry, ISSN: 15204995 00062960

Eastman; Florian M. Wurm; Robert Van Reis; Deborah L. Higgins

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February 1, 1992

Engagement of major histocompatibility complex class II molecules by superantigen induces inflammatory cytokine gene expression in human rheumatoid fibroblast-like synoviocytes

Journal of Experimental Medicine, ISSN: 15409538 00221007

Walid Mourad; Khalil Mehindate; Thomas J. Schall; Shaun R. McColl

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February 1, 1992

Characterization of a Recombinant Extracellular Domain of the Type 1 Tumor Necrosis Factor Receptor: Evidence for Tumor Necrosis Factor-α Induced Receptor Aggregation

Biochemistry, ISSN: 15204995 00062960

Diane Pennica; Paul E. Borchardt; Lewis; David V. Goeddel; William J. Kohr; Helga Raab; Brian M. Fendly; Steven J. Shire

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February 1, 1992

The Type II Isoform of Bovine Brain Protein L-Isoaspartyl Methyltransferase Has an Endoplasmic Reticulum Retention Signal (…RDEL) at Its C-Terminus

Biochemistry, ISSN: 15204995 00062960

Steven M. Potter; Brett A. Johnson; Agnes Henschen; Aswad; Andrew W. Guzzetta

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February 1, 1992

Human Natriuretic Peptide Receptor-A Guanylyl Cyclase Is Self-Associated prior to Hormone Binding

Biochemistry, ISSN: 15204995 00062960

David G Lowe

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February 1, 1992

13C NMR Investigation of the Anomeric Specificity of CMP-TV-Acetylneuraminic Acid Synthetase from Escherichia coli

Biochemistry, ISSN: 15204995 00062960

Michael G. Ambrose; Freese; Mary S. Reinhold; Williie F. Vann; Warner

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February 1, 1992

The Ca2+Ion and Membrane Binding Structure of the Gla Domain of Ca-Prothrombin Fragment 1

Biochemistry, ISSN: 15204995 00062960

Soriano-Garcia; Kaillathe Padmanabhan; Alexander Tulinsky; De Vos

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February 1, 1992

Antigen Binding Thermodynamics and Antiproliferative Effects of Chimeric and Humanized anti-p185HER2 Antibody Fab Fragments

Biochemistry, ISSN: 15204995 00062960

Robert F. Kelley; Mark P. O'Connell; Paul J. Carter; Presta; Eigenbrot; Michael Covarrubias; Snedecor; James H. Bourell; David Vetterlein

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February 1, 1992

Mambin, a Potent Glycoprotein Ilb-IIIa Antagonist and Platelet Aggregation Inhibitor Structurally Related to the Short Neurotoxins

Biochemistry, ISSN: 15204995 00062960

Robert S. McDowell; Dennis; Michael G. Mulkerrin; Lazarus; Louie; Shuster

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February 1, 1992

Incorporation of a Stabilizing Ca2+-Binding Loop into Subtilisin BPN

Biochemistry, ISSN: 15204995 00062960

Braxton; James A. Wells

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January 31, 1992

A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Peter Gluckman; Nicolin Klempt; Jian Guan; Carina Mallard; Ernest Sirimanne; Mike Dragunow; Martin Klempt; Singh; Chris Williams; Nikolics

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January 1, 1992

Recognition of angiotensin II: Antibodies at different levels of an idiotypic network are superimposable

Science, ISSN: 00368075

Garcia; Desiderio; Pierre M. Ronco; Pierre J. Verroust; Amzel

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January 1, 1992

Antithrombotic effect of a monoclonal antibody against tissue factor in a rabbit model of platelet-mediated arterial thrombosis

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Ik-Kyung Jang; Herman K. Gold; Robert C. Leinbach; John T. Fallon; Desire Collen; Josiah N. Wilcox

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January 1, 1992

Glycosylation-dependent cell adhesion molecule 1: A novel mucin-like adhesion ligand for L-selectin

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Lasky; Mark S. Singer; Dowbenko; Yasuyuki Imai; William J. Henzel; Christopher Fennie; Susan R. Watson; Steven D. Rosen

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January 1, 1992

Recent studies on retrovirus-like particles in Chinese hamster ovary cells.

Developments in biological standardization, ISSN: 03015149

Dinowitz; Yolanda S. Lie; Mari-Anne L. Low; Lazar; Fautz; Beverly J. Potts; Sernatinger; Anderson

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January 1, 1992

Humanization of an anti-p185HER2 antibody for human cancer therapy

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Paul J. Carter; Presta; Cornelia M. Gorman; John B.B. Ridgway; Henner; Wai Lee T. Wong; Rowland; Claire Kotts; Monique E. Carver; Shepard

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January 1, 1992

Antibody expression in bacteriophage systems: The future of monoclonal antibodies?

Current Opinion in Biotechnology, ISSN: 09581669

Lisa J. Garrard; Eugene A. Zhukovsky

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January 1, 1992

Principles of the design and operational considerations of large scale high performance liquid chromatography (HPLC) systems for proteins and peptides purification.

Bioseparation, ISSN: 0923179X

Wisniewski

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January 1, 1992

Multiple domains of the RNA polymerase I activator hUBF interact with the TATA-binding protein complex hSL1 to mediate transcription

Genes and Development, ISSN: 08909369

Hans-Michael Jantzen; Alice M. Chow; David S. King; Robert Tjian

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January 1, 1992

Peptide stability in drug development: A comparison of peptide reactivity in different biological media

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Powell; Howard M. Grey; Federico C. A. Gaeta; Alessandro Sette; Colon

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January 1, 1992

Two TNF receptors

Immunology Today, ISSN: 01675699

Louis A. Tartaglia; David V. Goeddel

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January 1, 1992

Backbone Dynamics of the Bacillus subtilis Glucose Permease IIA Domain Determined from 15N NMR Relaxation Measurements

Biochemistry, ISSN: 15204995 00062960

Martin J. Stone; Peter E. Wright; Wayne J. Fairbrother; Arthur G. Palmer III; Jonathan Reizer; Milton H. Saier Jr.

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January 1, 1992

Petrology, petrochemistry, and stromatolites of the Middle to Late Proterozoic Beck Spring Dolomite, eastern Mojave Desert, California

Canadian Journal of Earth Sciences, ISSN: 00084077

Marian; Osborne

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January 1, 1992

Growth hormone augments superoxide anion secretion of human neutrophils by binding to the prolactin receptor

Journal of Clinical Investigation, ISSN: 00219738

Yung-Kang Fu; Sean Arkins; Germaine Fun; Cunningham; James A. Wells; Sherman Fong; Cronin; Robert Dantzer; Keith W. Kelley

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January 1, 1992

Evidence of a role for mesothelial cell-derived interleukin 8 in the pathogenesis of asbestos-induced pleurisy in rabbits

Journal of Clinical Investigation, ISSN: 00219738

Alice M. Boylan; Ruegg; Kim; Hébert; John M. Hoeffel; Robert Pytela; Dean Sheppard; Ira M. Goldstein; V. Courtney Broaddus

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January 1, 1992

Applications of Ultrafast HPLC to Process Development of Recombinant DNA‐Derived Proteins

Biotechnology Progress, ISSN: 15206033 87567938

Olson; Richard L. Gehant

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January 1, 1992

X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Gilbert G. Privé; Michael V. Milburn; Liang Tong; Abraham M. Devos; Ziro Yamaizumi; Nishimura; Sung-Hou Kim

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January 1, 1992

Reduction of α-naphthylisothiocyanate-induced hepatotoxicity by recombinant human hepatocyte growth factor

Endocrinology, ISSN: 19457170 00137227

Roos; Timothy G. Terrell; Godowski; Steven M. Chamow; Ralph H. Schwall

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January 1, 1992

Activin-A as an intraovarian modulator: Actions, localization, and regulation of the intact dimer in human ovarian cells

Journal of Clinical Investigation, ISSN: 00219738

Jaron Rabinovici; Susan J. Spencer; Nicola Doldi; Paul C. Goldsmith; Ralph H. Schwall; Robert B. Jaffe

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January 1, 1992

Monoclonal Antibodies to the Extracellular Domain of HIV-1IIIB gp160 that Neutralize Infectivity, Block Binding to CD4, and React with Diverse Isolates

AIDS Research and Human Retroviruses, ISSN: 19318405 08892229

Nakamura; Randal A. Byrn; Rosenthal; James P. Porter; Hobbs; Riddle; Eastman; Dowbenko; Timothy Gregory; Brian M. Fendly; Berman

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January 1, 1992

Three-dimensional structure of an angiotensin II-fab complex at 3 Å: Hormone recognition by an anti-idiotypic antibody

Science, ISSN: 00368075

Garcia; Pierre M. Ronco; Pierre J. Verroust; Axel T. Brünger; Amzel

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January 1, 1992

In vitro ligand binding of125I-recombinant human activin a to the female rat brain

Endocrinology, ISSN: 19457170 00137227

Lyn B. Jakeman; Mather; Woodruff

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January 1, 1992

In vivo import of firefly luciferase into the glycosomes of Trypanosoma brucei and mutational analysis of the C-terminal targeting signal

Molecular Biology of the Cell, ISSN: 10591524

Sommer; Qi-Lin Cheng; Gilbert-Andre Keller; Ching C. Wang

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January 1, 1992

Characterization of the Saccharomyces Golgi complex through the cell cycle by immunoelectron microscopy

Molecular Biology of the Cell, ISSN: 10591524

Preuss; Jon Mulholland; Alex Franzusoff; Nava Segev; David Botstein

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January 1, 1992

Development of humanized bispecitic antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene

Journal of Experimental Medicine, ISSN: 15409538 00221007

Shalaby; Shepard; Presta; Maria L. Rodrigues; Peter C. L. Beverley; Marc Feldmann; Paul J. Carter

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January 1, 1992

Antibody engineering

Current Opinion in Biotechnology, ISSN: 09581669

Presta

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January 1, 1992

Antibody engineering

Current Opinion in Structural Biology, ISSN: 0959440X

Presta

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January 1, 1992

Tetrapeptide inhibitors of protein farnesyltransferase: Ammo-terminal substitution in phenylalanine-containing tetrapeptides restores farnesylation

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Michael S. Brown; Joseph L. Goldstein; Kenneth J. Paris; Burnier; James C. Marsters Jr.

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January 1, 1992

Assignment of the Aliphatic 1H and 13C Resonances of the Bacillus Subtilis Glucose Permease IIA Domain Using Double- and Triple-Resonance Heteronuclear Three-Dimensional NMR Spectroscopy

Biochemistry, ISSN: 15204995 00062960

Mark Ranee; Peter E. Wright; Wayne J. Fairbrother; Arthur G. Palmer III; Jonathan Reizer; Milton H. Saier Jr.

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