Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13951 - 14000 OF 15217 RESULTS

December 20, 1991

Crystals of the complex between human growth hormone and the extracellular domain of its receptor

Journal of Molecular Biology, ISSN: 00222836

Ultsch; De Vos; Anthony A. Kossiakoff

December 1, 1991

Cell transformation potential of a HER2 transmembrane domain deletion mutant retained in the endoplasmic reticulum

Journal of Biological Chemistry, ISSN: 00219258

Hudziak; Axel Ullrich

December 1, 1991

Generation of polyclonal antibodies against recombinant human acitvin a

Journal of Immunoassay, ISSN: 01971522

James A. Lofgren; Ralph H. Schwall; Charles H. Schmelzer; Wai Lee T. Wong

December 1, 1991

Determining the optimum residual moisture in lyophilized protein pharmaceuticals

Developments in biological standardization, ISSN: 03015149

Chung C. Hsu; Carole A. Ward; Rodney Pearlman; Hoc M. Nguyen; Yeung; Curley

December 1, 1991

Structure of the lutropin/choriogonadotropin receptor

Recent Progress in Hormone Research, ISSN: 00799963

Deborah L. Segaloff; Rolf Sprengel; Nikolics; Mario Ascoli

December 1, 1991

Growth hormone receptor and binding protein

Recent Progress in Hormone Research, ISSN: 00799963

Steven A. Spencer; Leung; Godowski; Glenn Hammonds; Michael J. Waters; William I. Wood

December 1, 1991

Characterization of the Tryptic Map of Recombinant DNA Derived Tissue Plasminogen Activator by High-Performance Liquid Chromatography-Electrospray Ionization Mass Spectrometry

Analytical Chemistry, ISSN: 15206882 00032700

Victor Ling; Andrew W. Guzzetta; Eleanor Canova-Davis; Stults; William S. Hancock; Covey; Shushan

December 1, 1991

Extracellular domain-IgG fusion proteins for three human natriuretic peptide receptors: Hormone pharmacology and application to solid phase screening of synthetic peptide antisera

Journal of Biological Chemistry, ISSN: 00219258

Brian D. Bennett; Bennett; Roderick V. Vitangcol; Jewett; Burnier; William J. Henzel; David G Lowe

December 1, 1991

p185(HER2) signal transduction in breast cancer cells

Journal of Biological Chemistry, ISSN: 00219258

Gary K. Scott; James M. Dodson; Pamela A. Montgomery; Johnson; Jay Sarup; Wai Lee T. Wong; Axel Ullrich; Shepard; Benz

November 27, 1991

A nonfunctional sequence converted to a signal for glycophosphatidylinositol membrane anchor attachment

Journal of Cell Biology, ISSN: 00219525

Paul Moran; Caras

November 22, 1991

Scanning mutagenesis of interleukin-8 identifies a cluster of residues required for receptor binding

Journal of Biological Chemistry, ISSN: 00219258

Hébert; Roderick V. Vitangcol; Baker

November 11, 1991

A to G substitution identified in exon 2 of the G6PD gene among G6PD deficient chinese

Nucleic Acids Research, ISSN: 03051048

Lotung Chao; Chuan-su Du; Elaine Louie; Lin Zuo; Ellson Y. Chen; Bertram Lubin; Daniel T.Y. Chiu

November 8, 1991

Primary structure and functional expression of the human receptor for Escherichia coli heat-stable enterotoxin

Journal of Biological Chemistry, ISSN: 00219258

Frederic J. De Sauvage; Camerato; David V. Goeddel

November 5, 1991

The importance of a distal hydrogen bonding group in stabilizing the transition state in subtilisin BPN

Journal of Biological Chemistry, ISSN: 00219258

Braxton; James A. Wells

November 1, 1991

The vascular endothelial growth factor family of polypeptides

Journal of Cellular Biochemistry, ISSN: 10974644 07302312

Napoleone Ferrara; Houck; Lyn B. Jakeman; Jane Winer; Leung

November 1, 1991

Selecting High-Affinity Binding Proteins by Monovalent Phage Display

Biochemistry, ISSN: 15204995 00062960

Henry B. Lowman; Bass; Simpson; James A. Wells

October 31, 1991

Two commonly occurring nucleotide base substitutions in Chinese G6PD variants

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Daniel T.Y. Chiu; Lin Zuo; Ellson Y. Chen; Lotung Chao; Elaine Louie; Bertram Lubin; Tsan Z. Liu; Chuan-su Du

October 18, 1991

Fractionation of the human recombinant tissue plasminogen activator (rtPA) glycoforms by high-performance capillary zone electrophoresis and capillary isoelectric focusing

Journal of Chromatography A, ISSN: 00219673

Yim

October 18, 1991

Selectins: A family of adhesion receptors

Cell, ISSN: 00928674

Bevilacqua; Eugene C. Butcher; Barbara C. Furie; Bruce Furie; Gallatin; Gimbrone Jr.; Harlan; Kishimoto; Lasky; Rodger P. McEver; Paulson; Steven D. Rosen; Seed; Siegelman; Springer; Stoolman; Thomas F. Tedder; Ajit Varki; Denisa D. Wagner; Irving L. Weissman; Zimmerman

September 27, 1991

Increase in glia-derived nerve growth factor following destruction of hippocampal neurons

Brain Research, ISSN: 00068993

Bakhit; Armanini; Bennett; Wai Lee T. Wong; Hansen; Taylor

September 20, 1991

Characterization of a tryptic digest by high-performance displacement chromatography and mass spectrometry

Journal of Chromatography A, ISSN: 00219673

John Frenz; Quan; William S. Hancock; James H. Bourell

September 9, 1991

Isolation and characterization of a succinimide variant of methionyl human growth hormone

Journal of Biological Chemistry, ISSN: 00219258

Glen Teshima; Stults; Victor Ling; Eleanor Canova-Davis

September 6, 1991

Mutational analysis and protein engineering of receptor-binding determinants in human placental lactogen

Journal of Biological Chemistry, ISSN: 00219258

Henry B. Lowman; Cunningham; James A. Wells

September 6, 1991

Effects of MGSA/GROα on melanocyte transformation

Oncogene, ISSN: 09509232

Balentien; Mufson; Shattuck; Rik Derynck; Richmond

September 5, 1991

X-ray structure of human relaxin at 1·5 Å. Comparison to insulin and implications for receptor binding determinants

Journal of Molecular Biology, ISSN: 00222836

Eigenbrot; Michael Randal; Quan; Burnier; O'Connell; Rinderknecht; Anthony A. Kossiakoff

September 4, 1991

Autoradiographic localization of relaxin binding sites in rat brain

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Phyllis L. Osheroff; Phillips

August 20, 1991

Distinguishing mammalian sialidases by inhibition kinetics with novel derivatives of 5-acetamido-2,6-anhydro-3,5-dideoxy-d-glycero-d-galacto-non-2-enonic acid, an unsaturated derivative of N-acetylneuraminic acid

Carbohydrate Research, ISSN: 00086215

Warner; Louie; Michel Potier; Anthony Ribeiro

August 16, 1991

Structure-activity relationship study of human interleukin-3. Identification of residues required for biological activity by site-directed mutagenesis

Journal of Biological Chemistry, ISSN: 00219258

Lokker; N. Rao Movva; Ulrike Strittmatter; Barbara Fagg; Gerhard Zenke

August 1, 1991

Self-Association of Human and Porcine Relaxin As Assessed by Analytical Ultracentrifugation and Circular Dichroism

Biochemistry, ISSN: 15204995 00062960

Steven J. Shire; Leslie A. Holladay; Rinderknecht

July 31, 1991

Crystallization and preliminary X-ray diffraction studies of recombinant rabbit interferon-gamma

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Cleopas T. Samudzi; Cynthia L. Gribskov; Louis E. Burton; Rubin

July 22, 1991

Rational scanning mutagenesis of a protein kinase identifies functional regions involved in catalysis and substrate interactions

Journal of Biological Chemistry, ISSN: 00219258

Gibbs; Zoller

July 19, 1991

Increase in nerve growth factor-like immunoreactivity and decrease in choline acetyltransferase following contusive spinal cord injury

Brain Research, ISSN: 00068993

Bakhit; Armanini; Wai Lee T. Wong; Bennett; Jean R. Wrathall

July 12, 1991

Entorhinal cortex lesion or intrahippocampal colchicine injection increases peripheral type benzodiazepine binding sites in rat hippocampus

Brain Research, ISSN: 00068993

Michel Baudry; Anthony Altar

July 11, 1991

Self-association of tissue factor as revealed by chemical cross-linking

Journal of Biological Chemistry, ISSN: 00219258

Roy; Lisa R. Paborsky; Gordon A. Vehar

July 11, 1991

High resolution analysis of functional determinants on human tissue-type plasminogen activator

Journal of Biological Chemistry, ISSN: 00219258

William F. Bennett; Nicholas F. Paoni; Keyt; David Botstein; Andrew J.S. Jones; Presta; Florian M. Wurm; Zoller

July 5, 1991

Proteinases of the mammary gland: Developmental regulation in vivo and vectorial secretion in culture

Development (Cambridge), ISSN: 09501991

Rabih S. Talhouk; Jennie R. Chin; Elaine N. Unemori; Zena Werb; Mina J. Bissell

July 1, 1991

Synthesis of a Tetramethyl Analogue of Teleocidin

Journal of Organic Chemistry, ISSN: 15206904 00223263

Robert R. Webb II; Michael C. Venuti; Eigenbrot

June 1, 1991

Probing the Mechanism and Improving the Rate of Substrate-Assisted Catalysis in Subtilisin BPN′

Biochemistry, ISSN: 15204995 00062960

Paul J. Carter; Lars Abrahmsén; James A. Wells

June 1, 1991

Identification of Electrostatic Interactions That Determine the Phosphorylation Site Specificity of the cAMP-Dependent Protein Kinase

Biochemistry, ISSN: 15204995 00062960

Gibbs; Zoller

June 1, 1991

Use of Recombinant DNA Derived Human Relaxin To Probe the Structure of the Native Protein

Biochemistry, ISSN: 15204995 00062960

Eleanor Canova-Davis; T. Jeremy Kessler; Paul-Jane Lee; David T.W. Fei; Patrick Griffin; Stults; John D. Wade; Rinderknecht

June 1, 1991

MHC class II-associated variation in the production of tumor necrosis factor in mice and humans: Relevance to the pathogenesis of autoimmune diseases

Immunologic Research, ISSN: 0257277X 15590755

Chaim O. Jacob; Gail D. Lewis; Hugh O. McDevitt

May 15, 1991

An SfiI restriction map of the Bacillus subtilis 168 genome

Gene, ISSN: 03781119

Amjad; Castro; Sandoval; Wu; Yang; Henner; Piggot

May 6, 1991

Both D factor/LIF and IL-6 inhibit the differentation of mouse teratocarcinoma F9 cells

FEBS Letters, ISSN: 00145793

Kazunori Hirayoshi; Akio Tsuru; Michiaki Yamashita; Tomida; Yuri Yamamoto-Yamaguchi; Kiyoshi Yasukawa; Hozumi; David V. Goeddel; Kazuhiro Nagata

May 1, 1991

Apolipoprotein(a): Expression and Characterization of a Recombinant Form of the Protein in Mammalian Cells

Biochemistry, ISSN: 15204995 00062960

Marlys L. Koschinsky; James E. Tomlinson; Zioncheck; Karen Schwartz; Dan L. Eaton; Lawn

May 1, 1991

Monoclonal antibody therapy of human cancer: Taking the HER2 protooncogene to the clinic

Journal of Clinical Immunology, ISSN: 15732592 02719142

Shepard; Gail D. Lewis; Jay Sarup; Brian M. Fendly; Daniel A. Maneval; Joyce Mordenti; Figari; Claire Kotts; Michael A. Palladino; Axel Ullrich; Dennis J. Slamon

May 1, 1991

Effect of recombinant inhibin on gonadotropin secretion during proestrus and estrus in the rat

Endocrinology, ISSN: 19457170 00137227

Catherine Rivier; Ralph H. Schwall; Anthony J. Mason; Louis E. Burton; Wylie Vale

May 1, 1991

Further characterization of insulin-like-growth factor binding proteins in rat osteoblast-like cell cultures: Modulation by 17β-estradiol and human growth hormone

Endocrinology, ISSN: 19457170 00137227

Theresa L. Chen; Frances Liu; Rebecca L. Bates; Hintz

April 17, 1991

Manganese-stimulated phosphorylation of a rat pancreatic protein: identity with elongation factor 2

Biochimica et Biophysica Acta - Molecular Cell Research, ISSN: 01674889

Simon A.B. Knight; William J. Kohr; Murray Korc

April 1, 1991

Engineering Subtilisin and Its Substrates for Efficient Ligation of Peptide Bonds in Aqueous Solution

Biochemistry, ISSN: 15204995 00062960

Lars Abrahms; Jeffrey Tom; Burnier; Karen A. Butcher; Anthony A. Kossiakoff; James A. Wells

April 1, 1991

Conformationally Restricted Arginine Analogues

Journal of Organic Chemistry, ISSN: 15206904 00223263

Thomas R. Webb; Eigenbrot

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