Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14151 - 14200 OF 15217 RESULTS

January 1, 1991

Parenteral Peptide Formulations: Chemical and Physical Properties of Native Luteinizing Hormone-Releasing Hormone (LHRH) and Hydrophobic Analogues in Aqueous Solution

Pharmaceutical Research, ISSN: 1573904X 07248741

Powell; Sanders; Alan Rogerson; Si

January 1, 1991

One chain variants of tissue plasminogen activator have increased susceptibility to inactivation by plasmin

Fibrinolysis and Proteolysis, ISSN: 02689499

Deborah L. Higgins; Young; Wong

January 1, 1991

Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Avi Ashkenazi; Scot A. Marsters; Capon; Steven M. Chamow; Figari; Diane Pennica; David V. Goeddel; Michael A. Palladino; Smith

January 1, 1991

Aortic smooth muscle cells express and secrete vascular endothelial growth factor

Growth Factors, ISSN: 08977194

Napoleone Ferrara; Jane Winer; Theresa Burton

January 1, 1991

Modifying effects of preexisting pulmonary fibrosis on biological responses of rats to inhaled 239 puo2

Health Physics, ISSN: 15385159 00179078

Lundgren; Mauderly; Rebar; Nancy Gillett; Hahn

January 1, 1991

Inactivation of drugs by blood

Acta Pharmaceutica Nordica, ISSN: 11001801

Cossum

January 1, 1991

Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma

Journal of Biological Chemistry, ISSN: 00219258

Dan L. Eaton; Malloy; Siao Ping Tsai; William J. Henzel; Drayna

January 1, 1991

Robotic applications: lessons on what constitutes success

Journal of Automatic Chemistry, ISSN: 01420453

Hutchins

January 1, 1991

Characterization of the murine homing receptor gene reveals correspondence between protein domains and coding exons

Genomics, ISSN: 10898646 08887543

Dowbenko; Anh Diep; Benjamin A. Taylor; Aldons J. Lusis; Lasky

January 1, 1991

Industrial scale harvest of proteins from mammalian cell culture by tangential flow filtration

Biotechnology and Bioengineering, ISSN: 10970290 00063592

Van Reis; Lee C. Leonard; Chung C. Hsu; Stuart E. Builder

January 1, 1991

Interaction of apolipoprotein(a) with apolipoprotein B-containing lipoproteins

Journal of Biological Chemistry, ISSN: 00219258

Vuong N. Trieu; Zioncheck; Lawn; Walter D. McConathy

January 1, 1991

Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Beat Knüsel; Winslow; Rosenthal; Louis E. Burton; Derice P. Seid; Karoly Nlkolics; Franz Hefti

January 1, 1991

Dimerization of human growth hormone by zinc

Science, ISSN: 00368075

Cunningham; Michael G. Mulkerrin; James A. Wells

January 1, 1991

Neutrophil influx into an inflammatory site inhibited by a soluble homing receptor-IgG chimaera

Nature, ISSN: 00280836

Susan R. Watson; Christopher Fennie; Lasky

January 1, 1991

Sticky sugars for selectins

Nature, ISSN: 00280836

Springer; Lasky

January 1, 1991

Mutations in human interferon gamma affecting inclusion body formation identified by a general immunochemical screen

Bio/Technology, ISSN: 0733222X

Wetzel; Jeanne Perry; Connie A. Veilleux

January 1, 1991

Lack of cardiovascular and vasopressin responses to human relaxin in conscious, late-pregnant rats

American Journal of Physiology - Heart and Circulatory Physiology, ISSN: 00029513

David G. Ward; Cronin; Baertschi

January 1, 1991

Liposomen: Fortschritte in Herstellungs‐Technologie und Therapie

Pharmazie in Unserer Zeit, ISSN: 16151003 00483664

Rubas; Schreier

January 1, 1991

Kringle‐2 domain of the tissue‐type plasminogen activator: 1H‐NMR assignments and secondary structure

European Journal of Biochemistry, ISSN: 14321033 00142956

In-Ja L. Byeon; Robert F. Kelley; Miguel Llinás

January 1, 1991

Improved electrospray ionization of synthetic oligodeoxynucleotides

Rapid Communications in Mass Spectrometry, ISSN: 10970231 09514198

Stults; James C. Marsters Jr.; Steve A. Carr

January 1, 1991

Effect of recombinant activin on androgen synthesis in cultured human thecal cells

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Hillier; Yong; Peter J. Illingworth; Baird; Ralph H. Schwall; Anthony J. Mason

December 15, 1990

Effect of heparin on coronary arterial patency after thrombolysis with tissue plasminogen activator in acute myocardial infarction

American Journal of Cardiology, ISSN: 00029149

Stanley D. Bleich; Timothy C. Nichols; Richard Schumacher; David H. Cooke; David A. Tate; Sam L. Teichman

December 1, 1990

Conformation of apolipoprotein B-100 in the low density lipoproteins of Tangier disease. Identification of localized conformational response to triglyceride content

Journal of Biological Chemistry, ISSN: 00219258

Kunitake; Stephen G. Young; G. Chi Chen; Clive R. Pullinger; Shan Zhu; Richard J. Pease; Jamie K. Scott; Hass; James Schilling; Kane

December 1, 1990

Immunoregulatory role of transforming growth factor β (TGF-β) in development of killer cells: Comparison of active and latent TGF-β1

Journal of Experimental Medicine, ISSN: 15409538 00221007

Wallick; Figari; Randall E. Morris; Levinson; Michael A. Palladino

December 1, 1990

Release of phenylpropanolamine from dynamically swelling poly(hydroxyethyl methacrylate-co-methacrylic acid) hydrogels

Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, ISSN: 07430515

Kou; Amidon

December 1, 1990

Post-translational modifications of recombinant human tissue factor

Thrombosis Research, ISSN: 00493848

Lisa R. Paborsky; Reed J. Harris

December 1, 1990

Requirement for sialic acid on the endothelial ligand of a lymphocyte homing receptor

Journal of Cell Biology, ISSN: 00219525

David D. True; Mark S. Singer; Lasky; Steven D. Rosen

December 1, 1990

Parathyroid hormone-related protein: Isolation, molecular cloning, and mechanism of action

Recent Progress in Hormone Research, ISSN: 00799963

Martin; Allan; Caple; Care; Danks; Diefenbach-Jagger; Ebeling; Gillespie; Glenn Hammonds Jr.; Heath; Hudson; Kemp; Kubota; Subhash C. Kukreja; Moseley; Ng; Raisz; Rodda; Simmons; Suva; Wettenhall; William I. Wood

December 1, 1990

Male-specific β-cell dysfunction and diabetes resulting from increased expression of a syngeneic MHC class I protein in the pancreata of transgenic mice

New Biologist, ISSN: 10434674

Martin; Gilbert-Andre Keller; Liggitt; Oakley; Sharon Pitts-Meek; Mark Siegel; Timothy G. Terrell; Stewart

December 1, 1990

Identification and design of binding determinants in proteins

Biochemical Society Symposium, ISSN: 00678694

James A. Wells; Cunningham

December 1, 1990

Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Shak; Capon; Renate Hellmiss; Scot A. Marsters; Baker

November 30, 1990

Photolabeling of the α-nueraminidase/β-galactosidase complex from human placenta with a photoreactive neuraminidase inhibitor

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Warner; Louie; Michel Potier

November 1, 1990

Recombinant Expression, Biochemical Characterization, and Biological Activities of the Human MGSA/gro Protein

Biochemistry, ISSN: 15204995 00062960

Rik Derynck; Duanzhi Wen; Rainer Brachmann; Wai Lee T. Wong; Jin Hee Han; H. Greg Thomas; Balentien; Richmond; Ajoy K. Samantha; Claus O. Zachariae; Kouji Matsushima; Patrick Griffin; Ann Richmond

November 1, 1990

Widespread intradermal accumulation of mononuclear leukocytes in lepromatous leprosy patients treated systemically with recombinant interferon γ

Journal of Experimental Medicine, ISSN: 15409538 00221007

Carl Nathan; Kathleen Squires; William Griffo; William Levis; Matthew Varghese; Job; Asma Nusrat; Stephen A. Sherwin; Samuel Rappoport; Elizabeth Sanchez; Rochel A. Burkhardt; Gilla Kaplan

November 1, 1990

Quantification of monoclonal antibodies in complex mixtures by Protein G high-performance liquid affinity chromatography

Analytical Biochemistry, ISSN: 10960309 00032697

Gregory S. Blank; David Vetterlein

October 23, 1990

cDNA sequence of the human integrin β5 subunit

Journal of Biological Chemistry, ISSN: 00219258

McLean; Deborah J. Vestal; David A. Cheresh; Bodary

October 11, 1990

Interferon-gamma and the sexual dimorphism of autoimmunity

Molecular Biology and Medicine, ISSN: 07351313

Sarvetnick; Howard S. Fox

October 1, 1990

Enzymatic Cleavage of a CD4 Immunoadhesin Generates Crystallizable, Biologically Active Fd-like Fragments

Biochemistry, ISSN: 15204995 00062960

Steven M. Chamow; Peers; Randal A. Byrn; Michael G. Mulkerrin; Reed J. Harris; Wen-Ching Wang; Pamela J. Bjorkman; Capon; Avi Ashkenazi

October 1, 1990

X-ray Crystal Structure of the Protease Inhibitor Domain of Alzheimer's Amyloid β-Protein Precursor

Biochemistry, ISSN: 15204995 00062960

Eigenbrot; Thomas R. Hynes; Michael Randal; Laura A. Kennedy; Charles Eigenbrot; Anthony A. Kossiakoff

October 1, 1990

The OxyR regulon

Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology, ISSN: 00036072 15729699

Gisela Storz; Louis A. Tartaglia; Bruce N. Ames

October 1, 1990

Antibody raised against soluble CD4-rgpl20 complex recognizes the cd4 moiety and blocks membrane fusion without inhibiting CD4-gpl20 binding

Journal of Experimental Medicine, ISSN: 15409538 00221007

Franco Celada; Caterina Cambiaggi; Joan Maccari; Samuele Burastero; Timothy Gregory; Patzer; James P. Porter; Charlene McDanal; Matthews

September 10, 1990

Regulation of G(i) and G(o) by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity

Journal of Biological Chemistry, ISSN: 00219258

Tsutomu Higashijima; Burnier; Elliott M. Ross

September 7, 1990

Use of high-performance capillary electrophoresis to monitor charge heterogeneity in recombinant-DNA derived proteins

Journal of Chromatography A, ISSN: 00219673

Shiaw-Lin Wu; Glen Teshima; Cacia; William S. Hancock

September 1, 1990

Additivity of Mutational Effects in Proteins

Biochemistry, ISSN: 15204995 00062960

James A. Wells

September 1, 1990

Carbohydrate Characterization of Recombinant Glycoproteins of Pharmaceutical Interest

Analytical Chemistry, ISSN: 15206882 00032700

Spellman

August 28, 1990

ELISA for quantitation of the extracellular domain of p185HER2 in biological fluids

Journal of Immunological Methods, ISSN: 00221759

Patricia E. Sias; Claire Kotts; David Vetterlein; Michael H. Shepard; Wai Lee T. Wong

August 25, 1990

Thermal denaturation profiles and gel mobility shift analysis of oligodeoxynucleotide triplexes

Nucleic Acids Research, ISSN: 03051048

Regan G. Shea; Ng; Norbert Bischofberger

August 20, 1990

βγ Dimers of G proteins inhibit atrial muscarinic K+ channels

Journal of Biological Chemistry, ISSN: 00219258

Koji Okabe; Yatani; Tony Evans; Yee-Kin Ho; Juan Codina; Lutz Birnbaumer; Arthur M. Brown

August 15, 1990

Serpin Inhibitors of Urokinase and Thrombin in Normal Rat Brain and the 9L Brain Tumor: Evidence for Elevated Expression of Protease Nexin I-like Inhibitor and a Novel Sodium Dodecyl Sulfate-activated Tumor Antithrombin

Cancer Research, ISSN: 15387445 00085472

Rao; Festoff; Baker; Morantz; Kimler; Evans

August 5, 1990

Overexpression of protein kinase C α-subtype in Swiss/3T3 fibroblasts causes loss of both high and low affinity receptor numbers for epidermal growth factor

Journal of Biological Chemistry, ISSN: 00219258

Hagit Eldar-Finkelman; Yaffa Zisman; Axel Ullrich; Etta Livneh

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