Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14401 - 14450 OF 15217 RESULTS

December 1, 1989

Expression of recombinant platelet glycoprotein IIbIIIa results in a functional fibrinogen-binding complex

Journal of Biological Chemistry, ISSN: 00219258

Bodary; Napier; McLean

November 15, 1989

Plasma desorption mapping of the tryptic digest of 23-kDa recombinant human growth hormone

Analytical Biochemistry, ISSN: 10960309 00032697

Ling Chen; Robert J. Cotter; Stults

November 1, 1989

Immunization procedures for E. coli proteins

Applied Biochemistry and Biotechnology, ISSN: 02732289 15590291

Vincent R. Anicetti; Martin A. Simonetti; Linda L. Blackwood; Andrew J.S. Jones; Chen

November 1, 1989

Characterization of recombinant human lymphotoxin (tumor necrosis factor-β) produced by a mammalian cell line

Archives of Biochemistry and Biophysics, ISSN: 10960384 00039861

Hains; Aggarwal

November 1, 1989

Mutational analysis of the conserved domains of a T-region border repeat of Agrobacterium tumefaciens

Plant Molecular Biology, ISSN: 01674412 15735028

van Haaren; Sedee; Herman A. de Boer; Schilperoort; Hooykaas

October 20, 1989

Crystallization and preliminary X-ray diffraction studies of bovine recombinant immune interferon

Journal of Molecular Biology, ISSN: 00222836

Rubin; Louis E. Burton

October 15, 1989

γ-Interferon-induced monocyte major histocompatibility complex class II antigen expression in individuals with acquired immune deficiency syndrome

Cellular Immunology, ISSN: 10902163 00088749

Otoniel Martínez-Maza; Ronald T. Mitsuyasu; Steven A. Miles; Janis V. Giorgi; Daniel F. Heitjan; Stephen A. Sherwin; John L. Fahey

September 8, 1989

Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor

Cell, ISSN: 00928674

Grace H.W. Wong; Jim H. Elwell; Larry W. Oberley; David V. Goeddel

August 11, 1989

The complete nucleotide sequence of the human gonadotropin-releasing hormone gene

Nucleic Acids Research, ISSN: 03051048

Hayflick; Adelman; Peter H. Seeburg

August 11, 1989

Expression of the H-ras proto-oncogene is controlled by alternative splicing

Cell, ISSN: 00928674

Justus B. Cohen; Susan D. Broz; Levinson

August 1, 1989

pH Dependence of the Reversible and Irreversible Thermal Denaturation of γ Interferons

Biochemistry, ISSN: 15204995 00062960

Michael G. Mulkerrin; Wetzel

July 1, 1989

Epidermal Growth Factor and Transforming Growth Factor a Bind Differently to the Epidermal Growth Factor Receptor

Biochemistry, ISSN: 15204995 00062960

Winkler; Lynn O'Connor; Marcy Winget; Brian M. Fendly

July 1, 1989

A phase I trial of recombinant human interferon-γ in patients with Kaposi's sarcoma and the acquired immunodeficiency syndrome (AIDS)

Journal of Clinical Immunology, ISSN: 02719142 15732592

H.Clifford Lane; Richard T. Davey Jr.; Stephen A. Sherwin; Henry Masur; Alain H. Rook; Jody F. Manischewitz; Gerald V. Quinnan; Phillip D. Smith; Margaret E. Easter; Anthony S. Fauci

June 21, 1989

Simple modification of a commercial flow cytometer to triple laser excitation. Simultaneous five-color fluorescence detection

Journal of Immunological Methods, ISSN: 00221759

John D. Woronicz; Glenn C. Rice

June 15, 1989

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Napoleone Ferrara; William J. Henzel

June 15, 1989

Substance P primes human neutrophil activation: A mechanism for neurological regulation of inflammation

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Axel Perianin; Ralph Snyderman; Bernard Malfroy

May 30, 1989

Multiple chromatographic forms of the formylpeptide chemoattractant receptor and their relationship to GTP-binding proteins

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Paul G. Polakis; Tony Evans; Ralph Snyderman

May 30, 1989

Molecular cloning and amino acid sequence of rat kidney aminopeptidase M: A member of a super family of zinc-metallohydrolases

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Bernard Malfroy; Helen Kado-Fong; Claude Gros; Bruno Giros; Jean-Charles Schwartz; Renate Hellmiss

May 1, 1989

Native gel activity stain and preparative electrophoretic method for the detection and purification of pyridine nucleotide-linked dehydrogenases

Analytical Biochemistry, ISSN: 10960309 00032697

Jana L. Seymour; Lazarus

April 15, 1989

Structure of the 5' flanking region of the gene encoding human parathyroid-hormone-related protein (PTHrP)

Gene, ISSN: 03781119

Suva; Mather; Gillespie; Webb; Ng; Genine Winslow; William I. Wood; Martin; Hudson

April 14, 1989

Characterization of G25K, a GTP-binding protein containing a novel putative nucleotide binding domain

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Paul G. Polakis; Ralph Snyderman; Tony Evans

April 5, 1989

Are there more tumor necrosis factors?

Journal of the National Cancer Institute, ISSN: 00278874

Michael A. Palladino

April 1, 1989

Stimulus-specific production of cyclooxygenase and lipoxygenase metabolites of arachidonic acid by bovine alveolar macrophages

Inflammation, ISSN: 03603997 15732576

Laegreid; Taylor; Englen; Straub; Silflow; Liggitt; Leid

March 24, 1989

Cloning of a lymphocyte homing receptor reveals a lectin domain

Cell, ISSN: 00928674

Lasky; Mark S. Singer; Ted A. Yednock; Dowbenko; Christopher Fennie; Rodriguez; Nguyen; Scott E. Stachel; Steven D. Rosen

March 1, 1989

Effects of CKS-17, a synthetic retroviral envelope peptide, on cell-mediated immunity in vivo: Immunosuppression, immunogenicity, and relation to immunosuppressive tumor products

Cancer Immunology, Immunotherapy, ISSN: 03407004 14320851

Margaret Nelson; David S. Nelson; George J. Cianciolo; Ralph Snyderman

February 24, 1989

Transmembrane TGF-α precursors activate EGF/TGF-α receptors

Cell, ISSN: 00928674

Rainer Brachmann; Patricia B. Lindquist; Mariko Nagashima; William J. Kohr; Michael T. Lipari; Napier; Rik Derynck

February 15, 1989

Preferential cleavage of amino- and carboxyl-terminal oligopeptides from vasoactive intestinal polypeptide by human recombinant enkephalinase (neutral endopeptidase, EC 3.4.24.11)

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Edward J. Goetzl; Sunil P. Sreedharan; Christoph W. Turck; Robert L. Bridenbaugh; Bernard Malfroy

February 10, 1989

Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell

Cell, ISSN: 00928674

Avi Ashkenazi; Ernest G. Peralta; Winslow; Ramachandran; Capon

January 1, 1989

A yeast actin-binding protein is encoded by SAC6, a gene found by suppression of an actin mutation

Science, ISSN: 00368075

Alison E. M. Adams; David Botstein; Drubin

January 1, 1989

Absorption of human growth hormone from the rat lung.

Biotechnology Therapeutics, ISSN: 08982848

John R. Patton; McCabe; Hansen; Daugherty

January 1, 1989

Substrate Specificities of Growth Factor Associated Kallikreins of the Mouse Submandibular Gland

Biochemistry, ISSN: 15204995 00062960

Michael Blaber; Paul J. Isackson; James C. Marsters Jr.; Burnier; Ralph A. Bradshaw

January 1, 1989

Connective tissue metabolism including cytokines

Current Opinion in Rheumatology, ISSN: 10408711

Edward P. Amento

January 1, 1989

Lutropin-choriogonadotropin receptor: An unusual member of the G protein-coupled receptor family

Science, ISSN: 00368075

McFarland; Rolf Sprengel; Phillips; Martin Köhler; Nora Rosemblit; Nikolics; Deborah L. Segaloff; Peter H. Seeburg

January 1, 1989

Rapid Kinetics of α2-Adrenergic Inhibition of Adenylate Cyclase. Evidence for a Distal Rate-Limiting Step

Biochemistry, ISSN: 15204995 00062960

William J. Thomsen; Richard R. Neubig

January 1, 1989

Purification of Recombinant Human Tissue Factor

Biochemistry, ISSN: 15204995 00062960

Lisa R. Paborsky; Keri M. Tate; Reed J. Harris; Yansura; Louise Band; Glynis McCray; Cornelia M. Gorman; Donogh P. O'Brien; Judy H. Chang; James R. Swartz; Victor P. Fung; James N. Thomas; Gordon A. Vehar

January 1, 1989

Fragments of Bovine Insulin-like Growth Factors I and II Stimulate Proliferation of Rat L6 Myoblast Cells

Biochemistry, ISSN: 15204995 00062960

Yasuo Konishi; Claire Kotts; Lea Doerr Bullock; Jacob S. Tou; Debra A. Johnson

January 1, 1989

Generic trans-kingdom sex?

Nature, ISSN: 00280836

Scott E. Stachel; Patricia C. Zambryski

January 1, 1989

Purification and Characterization of Tissue Plasminogen Activator Kringle-2 Domain Expressed in Escherichia coli

Biochemistry, ISSN: 15204995 00062960

Scott Cleary; Michael G. Mulkerrin; Robert F. Kelley

January 1, 1989

The MHC-binding and gpl20-binding functions of CD4 are separable

Science, ISSN: 00368075

Daniel Lamarre; Avi Ashkenazi; Sylvain Fleury; Smith; Rafick-P. Sekaly; Capon

January 1, 1989

Human transforming growth factor-β3: Recombinant expression, purification, and biological activities in comparison with transforming growth factors-β1 and -β2

Molecular Endocrinology, ISSN: 19449917 08888809

Graycar; Duncan A. Miller; Arrick; Lyons; Moses; Rik Derynck

January 1, 1989

Protein Engineering of Disulfide Bonds in Subtilisin BPN'

Biochemistry, ISSN: 15204995 00062960

Colin Mitchinson; James A. Wells

January 1, 1989

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

Science, ISSN: 00368075

Dennis J. Slamon; William Godolphin; Lovell A. Jones; John A. Holt; Steven Wong; Duane E. Keith; Wendy J. Levin; Susan G. Stuart; Judy Udove; Axel Ullrich; Michael F. Press

January 1, 1989

Designing CD4 immunoadhesins for AIDS therapy

Nature, ISSN: 00280836

Capon; Steven M. Chamow; Joyce Mordenti; Scot A. Marsters; Timothy Gregory; Hiroaki Mitsuya; Randal A. Byrn; Catherine Lucas; Florian M. Wurm; Jerome E. Groopman; Samuel Broder; Smith

January 1, 1989

Fibroblasts transformed with v-src show enhanced formation of an inositol tetrakisphosphate

Science, ISSN: 00368075

Johnson; Wasilenko; Matringly; Weber; Garrison

January 1, 1989

Peptide-based radioimmunoassay for insulin receptor. Detection of insulin-stimulated downregulation in IM-9 lymphocytes

Diabetes, ISSN: 00121797

McFarland; Ramachandran; Grunfeld

January 1, 1989

Pharmacologic basis for the safety assessment of recombinant human proteins

Journal of the American College of Toxicology, ISSN: 07300913

Cossum

January 1, 1989

Monoclonal Antibodies: Production, Purification, and Technology

Advances in Clinical Chemistry, ISSN: 00652423

David Vetterlein

January 1, 1989

Synthesis of novel polycyclic nucleoside analogues incorporation into oligodeoxynucleotides, and interaction with complementary sequences

Journal of the American Chemical Society, ISSN: 15205126 00027863

Norbert Bischofberger; Matteucci

January 1, 1989

Cloning and expression of the cDNA for the murine interferon γ receptor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Patrick W. Gray; Leong; Fennie; Farrar; Pingel; Fernandez-Luna; Schreiber

January 1, 1989

A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

Nature, ISSN: 00280836

Duncan W. Wilson; Celeste A. Wilcox; Gregory C. Flynn; Ellson Y. Chen; Wun-Jing Kuang; William J. Henzel; Marc R. Block; Axel Ullrich; James E. Rothman

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