Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14701 - 14750 OF 15217 RESULTS

November 13, 1987

Human relaxin increases cyclic AMP levels in cultured anterior pituitary cells

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Cronin; Malaska; Bakhit

November 4, 1987

Characterization of recombinant human factor VIII

Journal of Biological Chemistry, ISSN: 00219258

Eaton; Hass; Riddle; Mather; Wiebe; Timothy Gregory; Gordon A. Vehar

November 1, 1987

Tumor necrosis factors alpha and beta in acquired immunodeficiency syndrome (AIDS) and aids-related complex

Journal of Clinical Immunology, ISSN: 02719142 15732592

Arthur J. Ammann; Michael A. Palladino; Paul Volberding; Donald Abrams; Natasha L. Martin; Marcus Conant

November 1, 1987

Dog mastocytoma tryptase: Affinity purification, characterization, and amino-terminal sequence

Archives of Biochemistry and Biophysics, ISSN: 10960384 00039861

George H. Caughey; Nona F. Viro; Ramachandran; Stephen C. Lazarus; D.Benjamin Borson; Jay A. Nadel

October 23, 1987

Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing

Cell, ISSN: 00928674

Honegger; Dull; Felder; Van Obberghen; Bellot; Szapary; Schmidt; Axel Ullrich; Schlessinger

October 9, 1987

Sequence analysis, cellular localization, and expression of a neuroretina adhesion and cell survival molecule

Cell, ISSN: 00928674

Berman; Patrick W. Gray; Ellson Y. Chen; Keyser; Ehrlich; Karten; LaCorbiere; Esch; Schubert

October 9, 1987

Protein sequence of DMD gene is related to actin-binding domain of α-actinin

Cell, ISSN: 00928674

R. Glenn Hammonds

October 1, 1987

Inhibition of cytotoxic T cell development by transforming growth factor β and reversal by recombinant tumor necrosis factor α

Journal of Experimental Medicine, ISSN: 15409538 00221007

Ranges; Figari; Espevik; Michael A. Palladino

October 1, 1987

Cloning and expression of human tissue factor cDNA

Thrombosis Research, ISSN: 00493848

Karen L. Fisher; Cornelia M. Gorman; Gordon A. Vehar; Donogh P. O'Brien; Lawn

September 25, 1987

Two polymorphisms in the human lipoprotein lipase (LPL) gene

Nucleic Acids Research, ISSN: 03051048

Karen L. Fisher; Garret A. Fitzgerald; Lawn

September 11, 1987

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

Cell, ISSN: 00928674

Lasky; Nakamura; Smith; Christopher Fennie; Shimasaki; Patzer; Berman; Timothy Gregory; Capon

August 7, 1987

Partial amino acid sequence of apolipoprotein(a) shows that it is homologous to plasminogen

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Dan L. Eaton; Fless; William J. Kohr; McLean; Xu; Miller; Lawn; Scanu

August 1, 1987

Improvement in the alkaline stability of subtilisin using an efficient random mutagenesis and screening procedure

Protein Engineering, Design and Selection, ISSN: 17410126

Cunningham; James A. Wells

August 1, 1987

Inhibition of cytokine production by cyclosporin a and transforming growth factor β

Journal of Experimental Medicine, ISSN: 15409538 00221007

Espevik; Figari; Refaat Shalaby; Lackides; Gail D. Lewis; Michael Shepard; Michael A. Palladino

July 24, 1987

Characterization of the antitumor activities of human tumor necrosis factor-α and the comparison with other cytokines: Induction of tumor-specific immunity

Journal of Immunology, ISSN: 00221767

Michael A. Palladino; Shalaby; Susan M. Kramer; Ferraiolo; Baughman; Deleo; Crase; Marafino Jr.; Aggarwal; Figari

June 11, 1987

Multiple RFLPs at the human cholesteryl ester transfer protein (CETP) locus

Nucleic Acids Research, ISSN: 03051048

Drayna; Lawn

May 26, 1987

Template-primer analogs as substrates for DNA polymerase

Nucleic Acids Research, ISSN: 03051048

Thomas R. Webb; Jhurani; Ng

May 11, 1987

The murine tumor necrosis factor-beta (lymphotoxin) gene sequence

Nucleic Acids Research, ISSN: 03051048

Patrick W. Gray; Ellson Y. Chen; Chang-Ben Li; Wei-Liang Tang; Nancy Ruddle

April 29, 1987

Designing substrate specificity by protein engineering of electrostatic interactions

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James A. Wells; Powers; Bott; Graycar; David A. Estell

April 24, 1987

Compilation and comparison of the sequence context around the AUG startcodons in Saccharomyces cerevisiae mRNAs

Nucleic Acids Research, ISSN: 03051048

Robert W. Hamilton; Colin K. Watanabe; Herman A. de Boer

April 24, 1987

Primary structure of the human beta-adrenergic receptor gene

Nucleic Acids Research, ISSN: 03051048

Peter R. Schofield; Lucy M. Rhee; Ernest G. Peralta

April 14, 1987

Molecular cloning and amino acid sequence of rat enkephalinase

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Bernard Malfroy; Peter R. Schofield; Wun-Jing Kuang; Peter H. Seeburg; Anthony J. Mason; William J. Henzel

April 10, 1987

Intron-exon structure of the human transforming growth factor-β precursor gene

Nucleic Acids Research, ISSN: 03051048

Rik Derynck; Lucy M. Rhee; Ellson Y. Chen; Ann van Tilburg

April 10, 1987

Sequence of the porcine transforming growth factor-beta precursor

Nucleic Acids Research, ISSN: 03051048

Rik Derynck; Lucy M. Rhee

March 13, 1987

GnRH-associated peptide (GAP) is cosecreted with GnRH into the hypophyseal portal blood of ovariectomized sheep

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Clarke; Cummins; Karsch; Peter H. Seeburg; Nikolics

February 27, 1987

New substrates for enkephalinase (neutral endopeptidase) based on fluorescence energy transfer

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Bernard Malfroy; Burnier

February 27, 1987

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

Cell, ISSN: 00928674

Mark A. Muesing; Smith; Capon

February 13, 1987

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

Cell, ISSN: 00928674

Cornelius Knabbe; Marc E. Lippman; Lalage M. Wakefield; Kathleen C. Flanders; Attan Kasid; Rik Derynck; Robert B. Dickson

February 13, 1987

Different transforming growth factor-α species are derived from a glycosylated and palmitoylated transmembrane precursor

Cell, ISSN: 00928674

Timothy S. Bringman; Patricia B. Lindquist; Rik Derynck

February 1, 1987

Synthesis of Messenger RNAs for Transforming Growth Factors α and β and the Epidermal Growth Factor Receptor by Human Tumors

Cancer Research, ISSN: 15387445 00085472

Rik Derynck; David V. Goeddel; Axel Ullrich; Timothy S. Bringman; Berger; Jordan U. Gutterman; Richard D. Williams

February 1, 1987

The role of cysteine oxidation in the thermal inactivation of t4 lysozyme

Protein Engineering, Design and Selection, ISSN: 17410126

Perry; Wetzel

January 26, 1987

Human, yeast and hybrid 3-phosphoglycerate kinase gene expression in yeast

Nucleic Acids Research, ISSN: 03051048

Christina Y. Chen; Ronald A. Hitzeman

January 26, 1987

Cleavage of single stranded oligonucleotides by EcoRI restriction endonuclease

Nucleic Acids Research, ISSN: 03051048

Norbert Bischofberger; Ng; Thomas R. Webb; Matteucci

January 16, 1987

Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes

Cell, ISSN: 00928674

David G Lowe; Capon; Eric Delwart; Alan Y. Sakaguchi; Susan L. Naylor; David V. Goeddel

January 1, 1987

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

EMBO Journal, ISSN: 02614189

Ernest G. Peralta; Avi Ashkenazi; Winslow; Smith; Ramachandran; Capon

January 1, 1987

Effect of phorbol esters on down-regulation and redistribution of cell surface receptors for tumor necrosis factor-alpha.

Journal of Biological Chemistry, ISSN: 00219258

Aggarwal; Eessalu

January 1, 1987

α2-antiplasmin enschede: Alanine insertion and abolition of plasmin inhibitory activity

Science, ISSN: 00368075

William E. Holmes; Lijnen; Nelles; Kluft; Nieuwenhuis; Rijken; Desire Collen

January 1, 1987

Corticotropin Receptors

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Ramachandran; TSUBOKAWA; GOHIL

January 1, 1987

Characterization of Recombinant Human a2-Antiplasmin and of Mutants Obtained by Site-Directed Mutagenesis of the Reactive Site

Biochemistry, ISSN: 15204995 00062960

William E. Holmes; Lijnen; Desire Collen

January 1, 1987

Possible relationships between in vivo antitumour activity and toxicity of tumour necrosis factor-alpha.

CIBA Foundation Symposia, ISSN: 03005208

Michael A. Palladino; John R. Patton; Figari; Shalaby

January 1, 1987

Monoclonal antibodies to human tumor necrosis factors alpha and beta: application for affinity purification, immunoassays, and as structural probes

Hybridoma, ISSN: 0272457X

Timothy S. Bringman; Aggarwal

January 1, 1987

Growth hormone receptor and serum binding protein: Purification, cloning and expression

Nature, ISSN: 00280836

Leung; Steven A. Spencer; Cachianes; R. Glenn Hammonds; Collins; William J. Henzel; Ross Barnard; Michael J. Waters; William I. Wood

January 1, 1987

Primary structure and mRNA localization of protein F1, a growth-related protein kinase C substrate associated with synaptic plasticity.

EMBO Journal, ISSN: 02614189

Rosenthal; Chan; William J. Henzel; Haskell; Wun-Jing Kuang; Ellson Y. Chen; Josiah N. Wilcox; Axel Ullrich; David V. Goeddel; Routtenberg

January 1, 1987

Structural basis of muscarinic acetylcholine receptor subtype diversity

Trends in Pharmacological Sciences, ISSN: 0165604X

Ernest G. Peralta; Winslow; Avi Ashkenazi; Smith; Ramachandran; Capon

January 1, 1987

A repetitive sequence element 3′ of the human c‐Ha‐ras1 gene has enhancer activity

Journal of Cellular Physiology, ISSN: 10974652 00219541

Justus B. Cohen; Walter; Levinson

January 1, 1987

A parathyroid hormone-related protein implicated in malignant hypercalcemia: Cloning and expression

Science, ISSN: 00368075

Suva; Genine Winslow; Wettenhall; R. Glenn Hammonds; Moseley; Diefenbach-Jagger; Rodda; Kemp; Rodriguez; Ellson Y. Chen; Hudson; Martin; William I. Wood

January 1, 1987

Production of Recombinant Coagulation Proteins

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Gordon A. Vehar

January 1, 1987

Interaction of One-Chain and Two-Chain Tissue Plasminogen Activator with Intact and Plasmin-Degraded Fibrin

Biochemistry, ISSN: 15204995 00062960

Deborah L. Higgins; Gordon A. Vehar

January 1, 1987

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

Nature, ISSN: 00280836

S. Joseph Leibovich; Peter J. Polverini; Shepard; David M. Wiseman; Vera Shively; Nureddin Nuseir

January 1, 1987

Directing Ribosomes to a Single mRNA Species: A Method to Study Ribosomal Rna Mutations and Their Effects on Translation of a Single Messenger in Escherichia coli

Methods in Enzymology, ISSN: 15577988 00766879

Hui; Jhurani; Herman A. de Boer

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