Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14751 - 14800 OF 15217 RESULTS

January 1, 1987

Identification of human uromodulin as the tamm-horsfall urinary glycoprotein

Science, ISSN: 00368075

Diane Pennica; William J. Kohr; Wun-Jing Kuang; Debbie Glaister; Aggarwal; Ellson Y. Chen; David V. Goeddel

January 1, 1987

Gonadal Development and Gametogenesis in the Hypogonadal Mouse Are Restored by Gene Transfer

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Anthony J. Mason; Pitts; Nikolics; Szonyi; Josiah N. Wilcox; Peter H. Seeburg; Stewart

January 1, 1987

Ovomucoid Third Domains from 100 Avian Species: Isolation, Sequences, and Hypervariability of Enzyme-Inhibitor Contact Residues

Biochemistry, ISSN: 15204995 00062960

Michael Laskowski Jr.; Ikunoshin Kato; Wojciech Ardelt; James Cook; Andrew Denton; Mark W. Emnie; William J. Kohr; Soon Jae Park; Kevin Parks; Barbara L. Schatzley; Oeyvind L. Schoenberger; Misao Tashiro; Gisela Vichot; Harry E. Whatley; Anna Wieczorek; Maciej Wieczorek

January 1, 1987

On the evolution of specificity and catalysis in subtilisin

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

James A. Wells; Cunningham; Graycar; David A. Estell; Paul J. Carter

January 1, 1987

Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene

Science, ISSN: 00368075

Dennis J. Slamon; Gary M. Clark; Steven Wong; Wendy J. Levin; Axel Ullrich; William L. McGuire

January 1, 1987

Regulation of neutrophil migration and superoxide production by recombinant tumor necrosis factors-α and -β: Comparison to recombinant interferon-γ and interleukin-1α

Blood, ISSN: 00064971

Figari; Mori; Michael A. Palladino

January 1, 1987

Blocking of HIV-1 infectivity by a soluble, secreted form of the CD4 antigen

Science, ISSN: 00368075

Smith; Randal A. Byrn; Scot A. Marsters; Timothy Gregory; Jerome E. Groopman; Capon

January 1, 1987

A national cooperative growth study on protropin

Acta Paediatrica Scandinavica, ISSN: 0001656X

Barry M. Sherman

January 1, 1987

Chicken Ovomucoid: Determination of Its Amino Acid Sequence, Determination of the Trypsin Reactive Site, and Preparation of All Three of Its Domains

Biochemistry, ISSN: 15204995 00062960

Ikunoshin Kato; James Schrode; William J. Kohr; Michael Laskowski Jr.

January 1, 1987

Development of partial tolerance to the gastrointestinal effects of high doses of recombinant tumor necrosis factor-α in rodents

Journal of Clinical Investigation, ISSN: 00219738

John R. Patton; Peters; McCabe; Crase; Hansen; Chen; Liggitt

January 1, 1987

Equilibrium and Kinetic Measurements of the Conformational Transition of Reduced Thioredoxin

Biochemistry, ISSN: 15204995 00062960

Robert F. Kelley; William Shalongc; Jagannadham; Earle Stellwagen

January 1, 1987

Alternative Splicing Increases the Diversity of the Human Protein Kinase C Family

DNA, ISSN: 15577430 01980238

Lisa Coussens; Lucy M. Rhee; Parker; Axel Ullrich

January 1, 1987

Industrial Scale Protein Purification: A Perspective

Bio/Technology, ISSN: 15206033 87567938

Nikos K. Harakas; Stuart E. Builder

January 1, 1987

Functional Role of Proteolytic Cleavage at Arginine-275 of Human Tissue Plasminogen Activator As Assessed by Site-Directed Mutagenesis

Biochemistry, ISSN: 15204995 00062960

Gordon A. Vehar; Keri M. Tate; Deborah L. Higgins; William E. Holmes; Winkler; Herbert Heyneker

January 1, 1987

Human tumour necrosis factors: structure and receptor interactions.

CIBA Foundation Symposia, ISSN: 03005208

Aggarwal; Aiyer; Diane Pennica; Patrick W. Gray; David V. Goeddel

January 1, 1987

Replacement of Proline-76 with Alanine Eliminates the Slowest Kinetic Phase in Thioredoxin Folding

Biochemistry, ISSN: 15204995 00062960

Robert F. Kelley; Frederic M. Richards

January 1, 1987

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

EMBO Journal, ISSN: 02614189

Yarden; Wun-Jing Kuang; Yang-Feng; Lisa Coussens; Munemitsu; Dull; Ellson Y. Chen; Schlessinger; Uta Francke; Axel Ullrich

January 1, 1987

Tissue-Specific and Developmentally Regulated Transcription of the Insulin-Like Growth Factor 2 Gene

DNA, ISSN: 15577430 01980238

Gray; Tam; Dull; Hayflick; Pintar; Cavenee; Koufos; Axel Ullrich

January 1, 1987

Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells.

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Hudziak; Schlessinger; Axel Ullrich

January 1, 1987

Cloning and sequencing of human cholesteryl ester transfer protein cDNA

Nature, ISSN: 00280836

Drayna; Jarnagin; McLean; William J. Henzel; William J. Kohr; Fielding; Lawn

January 1, 1987

Assignment of the human gene for cholesteryl ester transfer protein to chromosome 16q12-16q21

Genomics, ISSN: 10898646 08887543

Aldons J. Lusis; Susan Zollman; Robert S. Sparkes; Ivana Klisak; Mohandas; Drayna; Lawn

January 1, 1987

Codon replacement in the PGK1 gene of Saccharomyces cerevisiae: experimental approach to study the role of biased codon usage in gene expression.

Molecular and Cellular Biology, ISSN: 02707306

Hoekema; Kastelein; Vasser; Herman A. de Boer

January 1, 1987

Heterologous expression and characterization of the human R-ras gene product.

Molecular and Cellular Biology, ISSN: 02707306

David G Lowe; David V. Goeddel

January 1, 1987

Primary structure and biochemical properties of an M2 muscarinic receptor

Science, ISSN: 00368075

Ernest G. Peralta; Winslow; Gary L. Peterson; Smith; Avi Ashkenazi; Ramachandran; Michael I. Schimerlik; Capon

January 1, 1987

Engineering enzyme specificity by "substrate-assisted catalysis"

Science, ISSN: 00368075

Paul J. Carter; James A. Wells

January 1, 1987

Receptor binding and activation of polymorphonuclear neutrophils by tumor necrosis factor-alpha

Journal of Leukocyte Biology, ISSN: 07415400

Shalaby; Michael A. Palladino; Sue E. Hirabayashi; Eessalu; Gail D. Lewis; Shepard; Aggarwal

January 1, 1987

Cloning of decay-Accelerating factor suggests novel use of splicing to generate two proteins

Nature, ISSN: 00280836

Caras; Davitz; Lucy M. Rhee; Weddell; Martin Jr.; Nussenzweig

January 1, 1987

Human lipoprotein lipase complementary DNA sequence

Science, ISSN: 00368075

Karen L. Wion; Kirchgessner; Aldons J. Lusis; Schotz; Lawn

January 1, 1987

Mutants of bovine pancreatic trypsin inhibitor lacking cysteines 14 and 38 can fold properly

Science, ISSN: 00368075

Cara Berman Marks; Hossein Naderi; Kosen; Kuntz; Anderson

January 1, 1987

Effects of growth factors on the antiproliferative activity of tumor necrosis factors

Cancer Research, ISSN: 15387445 00085472

Sugarman; Gail D. Lewis

January 1, 1987

Human purine nucleoside phosphorylase and adenosine deaminase: Gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses

Molecular and Cellular Biology, ISSN: 02707306

R.Scott McIvor; Johnson; Miller; Pitts; Steven R. Williams; Valerio; Martin Jr.; Verma

January 1, 1987

Harnessing disulfide bonds using protein engineering

Trends in Biochemical Sciences, ISSN: 09680004

Wetzel

January 1, 1987

GnRH-prohormone-containing neurons in the primate brain: Immunostaining for the GnRH-Associated peptide

Peptides, ISSN: 01969781

Tianbao Song; Nikolics; Peter H. Seeburg; Paul C. Goldsmith

January 1, 1987

Construction and properties of an intracellular serine protease mutant of Bacillus subtilis

Journal of Bacteriology, ISSN: 00219193

Louise Band; Henner; Ruppen

January 1, 1987

Regions of poliovirus protein VP1 produced in Escherichi coli induce neutralizing antibodies

Journal of Virology, ISSN: 0022538X

Hoatlin; Kew; Renz

January 1, 1987

Signal for attachment of a phospholipid membrane anchor in decay accelerating factor

Science, ISSN: 00368075

Caras; Weddell; Davitz; Nussenzweig; Martin Jr.

January 1, 1987

Molecular approaches to the study of gene mutation in human cells

Trends in Genetics, ISSN: 01689525

Robert B. DuBridge; Michele P. Calos

January 1, 1987

A human purine nucleoside phosphorylase deficiency caused by a single base change

Journal of Biological Chemistry, ISSN: 00219258

Steven R. Williams; Gekeler; R.Scott McIvor; Martin Jr.

January 1, 1987

Analysis of nucleotide sequences of two ligninase cDNAs from a white-rot filamentous fungus, Phanerochaete chrysosporium

Gene, ISSN: 03781119

Herman A. de Boer; Zhang; Collins; C.Adinarayana Reddy

January 1, 1987

Synthesis of 4-C substituted pyrimidine nucleosides

Tetrahedron Letters, ISSN: 00404039

Norbert Bischofberger

January 1, 1987

Leukotriene B4 Catabolism: Quantitation of Leukotriene B4 and Its ω-Oxidation Products by Reversed-Phase High-Performance Liquid Chromatography

Methods in Enzymology, ISSN: 15577988 00766879

Steven Shak

January 1, 1987

Determination of locust AKH-I by radioimmunoassay and the identification of an AKH-like factor in the locust brain

Insect Biochemistry, ISSN: 00201790

Pnina Moshitzky; Yamashiro; Laura Stuve; Ramachandran; Applebaum

January 1, 1987

Synthesis of adipokinetic hormone (AKH-I) in the locust brain

Insect Biochemistry, ISSN: 00201790

Pnina Moshitzky; William J. Henzel; Rafaeli; Ramachandran; Applebaum

January 1, 1987

Relaxin in human pregnancy serum measured with an homologous radioimmunoassay

Obstetrics and Gynecology, ISSN: 1873233X 00297844

Robin J. Bell; Lawrence W. Eddie; Arlene R. Lester; E.Carl Wood; Paul D. Johnston; Hugh D. Niall

January 1, 1987

Protein engineering '87—conference Report

Protein Engineering, Design and Selection, ISSN: 17410134 17410126

Michael Gait; Janet Thornton; Wetzel

January 1, 1987

Characterization and mapping of the Bacillus subtilis prtR gene

Journal of Bacteriology, ISSN: 00219193

Yang; Hidenori Shimotsu; Ferrari; Henner

January 1, 1987

Ultrastructural analysis of the anti-chlamydial activity of recombinant murine interferon-γ

Experimental and Molecular Pathology, ISSN: 10960945 00144800

Luis M. de la Maza; Michael J. Plunkett; Elaine J. Carlson; Ellena M. Peterson; Christine W. Czarniecki

January 1, 1987

Molecular biology of diazepam binding inhibitor

Neuropharmacology, ISSN: 00283908

Patrick W. Gray

January 1, 1987

Gordian knot loosened somewhat

Protein Engineering, Design and Selection, ISSN: 17410134 17410126

Wetzel

January 1, 1987

Phase II studies of recombinant human interferon gamma in metastatic renal cell carcinoma

Journal of Biological Response Modifiers, ISSN: 07326580

Jorge R. Quesada; Razelle Kurzrock; Stephen A. Sherwin; Jordan U. Gutterman

Join Our Team

The little things we do every day add up to big breakthroughs. Making a difference in the lives of millions starts when you make a change in yours.

Two Scientists Walk Into a Bar

Two Scientists Walk Into a Bar

Listen to our podcast, where researchers talk about their work answering the toughest questions in human biology.