Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 15501 - 15550 OF 15572 RESULTS

June 5, 1982

BIOSYNTHETIC METHIONYL HUMAN GROWTH HORMONE IS BIOLOGICALLY ACTIVE IN ADULT MAN

The Lancet, ISSN: 01406736

Hintz; Wilson; Finno; Rosenfeld; Bennett; Mcclellan; Swift

May 15, 1982

Characterization of intact and trypsin-digested biosynthetic human growth hormone by high-pressure liquid chromatography

Analytical Biochemistry, ISSN: 10960309 00032697

William J. Kohr; Rodney Keck; Harkins

May 14, 1982

Recombinant DNA-derived methionyl human growth hormone is similar in membrane binding properties to human pituitary growth hormone

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Rosenfeld; Aggarwal; Hintz; Laura A. Dollar

April 15, 1982

Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster

Journal of Molecular Biology, ISSN: 00222836

Axel Ullrich; Gray; David V. Goeddel; Dull

April 10, 1982

Variation in the sequence and modification state of the human insulin gene flanking regions

Nucleic Acids Research, ISSN: 03051048

Axel Ullrich; Dull; Gray; John A. Philips; Stephan Peter

April 1, 1982

Stimulation of Natural Killer Cell Activity and Inhibition of Proliferation of Various Leukemic Cells by Purified Human Leukocyte Interferon Subtypes

Cancer Research, ISSN: 15387445 00085472

Lee; Kelley; Chiu; Stebbing

April 1, 1982

Stimulation of Natural Killer Cell Activity and Inhibition of Proliferation of Various Leukemic Cells by Purified Human Leukocyte Interferon Subtypes

Cancer Research, ISSN: 15387445 00085472

Lee; Kelley; Henry Chiu; Stebbing

February 11, 1982

Human leukocyte interferon has no structural or biological relationship to corticotropin

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Wetzel; Levine; Hagman; Ramachandran

February 11, 1982

Bacteria-derived human growth hormone lacks lipolytic activity in rat adipose tissue

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Frigeri; Greg Robel; Stebbing

January 1, 1982

Interferon-induced inhibition of cell division and VSV replication in cells with no detectable RNase F activity

Federation Proceedings, ISSN: 00149446

Christine W. Czarniecki; Helmut Jacobsen; Robert M. Friedman; Patton T. Allen

January 1, 1982

pH Dependent behavior of purified biosynthetic human leukocyte interferon A (LIF-A)

Biophysical Journal, ISSN: 00063495

Steven J. Shire

January 1, 1982

The induction by LeIF of interferon and lymphotoxin in human peripheral blood leukocyte (PBL) cultures

International Journal of Immunopharmacology, ISSN: 01920561

Robbins

January 1, 1982

Regulated expression of human growth hormone genes in mouse cells

Cell, ISSN: 00928674

Diane M. Robins; Inbok Paek; Peter H. Seeburg; Richard Axel

January 1, 1982

Natural and Cloned Human Leukocyte Interferon in Herpesvirus Infections of Rabbit Eyes

Archives of Ophthalmology, ISSN: 15383601 00039950

Gilbert Smolin; Mitchell Friedlaender; Robert Friedlaender; Masao Okumoto; Stebbing

January 1, 1982

Antiviral activity of bacteria-derived human alpha interferons against encephalomyocarditis virus infection of mice

Infection and Immunity, ISSN: 00199567

Weck; Rinderknecht; David A. Estell; Stebbing

January 1, 1982

Antiviral effects of highly purified bacteria-derived human leukocyte interferons (subtypes a and d) and a human fibroblast interferon against herpes virus infection of the rabbit Eye

Current Eye Research, ISSN: 02713683

Giinther Grabner; Gilbert Smolin; Masao Okumoto; Stebbing

January 1, 1982

Immunoregulation by lymphokines. I. Human lymphotoxin induction of interferon activity

International Journal of Immunopharmacology, ISSN: 01920561

Svedersky; Robbins

January 1, 1982

High-performance liquid chromatography analysis in the synthesis, characterization, and reactions of neoglycopeptides

Analytical Biochemistry, ISSN: 10960309 00032697

Harvard Morehead; McKay; Wetzel

January 1, 1982

Antiviral and side effects of interferons produced by recombinant DNA techniques as tested in rhesus monkeys

Antiviral Research, ISSN: 01663542

Schellekens; Van Eerd; De Reus; Weck; Stebbing

January 1, 1982

Induction and augmentation of mitogen‐induced immune interferon production in human peripheral blood lymphocytes by Nα‐desacetylthymosin αl

European Journal of Immunology, ISSN: 15214141 00142980

Svedersky; Hui; May; McKay; Stebbing

January 1, 1982

Chiral Sulfoxidations Catalyzed by Rat Liver Cytochromes P-450

Biochemistry, ISSN: 15204995 00062960

David J. Waxman; Light; Christopher Walsh

January 1, 1982

Biogenesis of Epidithiadioxopiperazines. Nucleophilic Additions to Benzene Oxide and sym-Oxepin Oxide

Journal of Organic Chemistry, ISSN: 15206904 00223263

Toni Chancellor; Thomas J. Richard; William H. Rastetter

January 1, 1982

The Human Growth Hormone Gene Family: Nucleotide Sequences Show Recent Divergence and Predict a New Polypeptide Hormone

DNA, ISSN: 15577430 01980238

Peter H. Seeburg

January 1, 1982

Comparisons of dose-response data for various standard and recombinant DNA-derived human interferons

Journal of Virological Methods, ISSN: 01660934

Stebbing; May

January 1, 1982

Chitin-Bound Protein of Sarcophagid Larvae: Metabolism of Covalently Linked Aromatic Constituents

Biochemistry, ISSN: 15204995 00062960

Manickam Sugumaran; William J. Henzel; Kathleen Mulligan; Herbert Lipke

January 1, 1982

Direct Expression of Hepatitis B Surface Antigen in Monkey Cells from an SV40 Vector

DNA, ISSN: 15577430 01980238

Liu; Yansura; Levinson

January 1, 1982

Clustering of leukocyte and fibroblast interferon genes on human chromosome 9

Science, ISSN: 00368075

Thomas B. Shows; Alan Y. Sakaguchi; Susan L. Naylor; David V. Goeddel; Lawn

January 1, 1982

Carboxyterminal Region of Hybrid Leukocyte Interferons Affects Antiviral Specificity

DNA, ISSN: 15577430 01980238

Arthur E. Franke; Shepard; Houck; Leung; David V. Goeddel; Lawn

January 1, 1982

Fluoranthene: Synthesis and Mutagenicity of Four Diol Epoxides

Journal of Organic Chemistry, ISSN: 15206904 00223263

William H. Rastetter; Robert B. Nachbar Jr.; Sandra Russo-Rodriguez; Ruth V. Wattley; William G. Thilly; Barbara M. Andon; William L. Jorgensen; Mustafa Ibrahim

January 1, 1982

Proton Nuclear Magnetic Resonance Studies of Pseudomonas testosteroni 3-Oxo-Δ5-steroid Isomerase and Its Interaction with 17β-Estradiol

Biochemistry, ISSN: 15204995 00062960

William F. Benisek; John R. Ogez

January 1, 1982

Studies on the Chirality of Sulfoxidation Catalyzed by Bacterial Flavoenzyme Cyclohexanone Monooxygenase and Hog Liver Flavin Adenine Dinucleotide Containing Monooxygenase

Biochemistry, ISSN: 15204995 00062960

Light; David J. Waxman; Christopher Walsh

December 1, 1981

Assignment of the disulphide bonds of leukocyte interferon

Nature, ISSN: 00280836

Wetzel

December 1, 1981

Expression of a human gene for interferon in yeast

Nature, ISSN: 00280836

Ronald A. Hitzeman; Frank E. Hagie; Levine; David V. Goeddel; Gustav Ammerer; Benjamin D. Hall

December 1, 1981

A single amino acid change in IFN-β1 abolishes its antiviral activity

Nature, ISSN: 00280836

Shepard; Leung; Stebbing; David V. Goeddel

December 1, 1981

The structure of eight distinct cloned human leukocyte interferon cDNAs

Nature, ISSN: 00280836

David V. Goeddel; Leung; Dull; Mitchell Gross; Lawn; McCandliss; Peter H. Seeburg; Axel Ullrich; Elizabeth Yelverton; Patrick W. Gray

November 25, 1981

The sequence of human serum albumin cDNA and its expression in E. coli

Nucleic Acids Research, ISSN: 03051048

Lawn; Adelman; Susan C. Bock; Arthur E. Franke; Houck; Richard Najarian; Peter H. Seeburg; Karen L. Wion

November 25, 1981

Antiviral activities of hybrids of two major human leukocyte interferons

Nucleic Acids Research, ISSN: 03051048

Weck; Apperson; Stebbing; Patrick W. Gray; Leung; Michael Shepard; David V. Goeddel

September 1, 1981

Studies on the mode of action of single-stranded polynucleotides which are antiviral against encephalomyocarditis virus infection of mice

Archives of Virology, ISSN: 03048608 14328798

Stebbing

May 11, 1981

Conformational stability of alternating d (CG) oligomers in high salt solution

Nucleic Acids Research, ISSN: 03051048

Franco Quadrifoglio; Giorgio Manzini; Vasser; Kim Dinkelspiel; Roberto Crea

May 1, 1981

The proopiocortin (adrenocorticotropin/β-lipotropin) gene is located on chromosome 2 in humans

Somatic Cell Genetics, ISSN: 15729931 00980366

David Owerbach; William J. Rutter; James L. Roberts; Peter Whitfeld; John Shine; Peter H. Seeburg; Thomas B. Shows

April 1, 1981

The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21→qter

Human Genetics, ISSN: 03406717 14321203

Donna L. George; John A. Phillips; Uta Francke; Peter H. Seeburg

January 24, 1981

A system for shotgun DNA sequencing

Nucleic Acids Research, ISSN: 03051048

Joachim Messing; Roberto Crea; Peter H. Seeburg

January 1, 1981

Effect of interferon on hepatic cytochrome P-450 drug metabolizing systems

Pharmacologist, ISSN: 00317004

Singh; Kenneth W. Renton; Stebbing

January 1, 1981

Structural and functional domains of the Rous sarcoma virus transforming protein (pp60(src))

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Levinson; Courtneidge; J.Michael Bishop

January 1, 1981

In vitro synthesis of biologically active human leukocyte interferon directed by recombinant plasmid DNA

Archives of Biochemistry and Biophysics, ISSN: 10960384 00039861

Herbert Weissbach; David V. Goeddel; Russell Mc Candliss; Shuichiro Maeda; Philip C. Familletti; Betty Redfield; Theophil Staehelin; Sidney Pestka

January 1, 1981

Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli

Plasmid, ISSN: 10959890 0147619X

Jürgen Brosius; Axel Ullrich; Mary Alice Raker; Gray; Dull; Robin R. Gutell; Harry F. Noller

January 1, 1981

Human fibroblast interferon gene lacks introns

Nucleic Acids Research, ISSN: 03051048

Lawn; Adelman; Arthur E. Franke; Houck; Mitchell Gross; Richard Najarian; David V. Goeddel

January 1, 1981

Bacterial synthesis of a novel human leukocyte interferon

Nucleic Acids Research, ISSN: 03051048

Elizabeth Yelverton; Leung; Phillip Week; Patrick W. Gray; David V. Goeddel

January 1, 1981

Induction and augmentation of mitogen-induced lymphokine production in human PBL by N(α)-desacetylthymosin α1

Journal of Clinical Hematology and Oncology, ISSN: 01629360

Svedersky; Hui; Don

January 1, 1981

Direct Determination of the Protonation States of Aspartic Acid-102 and Histidine-57 in the Tetrahedral Intermediate of the Serine Proteases: Neutron Structure of Trypsin

Biochemistry, ISSN: 15204995 00062960

Anthony A. Kossiakoff; Steven A. Spencer

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