Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 2101 - 2150 OF 15217 RESULTS

Cobimetinib plus atezolizumab in BRAFV600 wild-type melanoma: primary results from the randomized phase III IMspire170 study
Annals of Oncology, ISSN: 15698041 09237534
Helen Gogas; Brigitte Dréno; James Larkin; Lev Demidov; Daniil Stroyakovskiy; Eroglu; Francesco Ferrucci; Pigozzo; Piotr Rutkowski; Mackiewicz; Isabelle Rooney; Athina Voulgari; Troutman; Bethany Pitcher; Guo; Yibing Yan; Marcela Castro; Sohail Mulla; Keith Flaherty; Arance
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Extended Characterization and Impact of Visible Fatty Acid Particles - A Case Study With a mAb Product
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Miguel Saggu; Barthélemy Demeule; Linda Jiang; Daniel Kammerer; Purnendu K. Nayak; Michelle Tai; Nina Xiao; Anthony Tomlinson
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Classification and Grading of Melanocytic Lesions in a Mouse Model of NRAS-driven Melanomagenesis
Journal of Histochemistry and Cytochemistry, ISSN: 15515044 00221554
Charles-Antoine Assenmacher; Sara F. Santagostino; Mark A. Oyama; Jean-Christophe Marine; Elise Bonvin; Enrico Radaelli
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Theoretical and Experimental Evaluation of Flow Pattern of Pharmaceutical Powder Blends Discharged From Intermediate Bulk Containers (IBCs)
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Ewa Nauka; Reto Maurer; Amilcar A. Gonzalez; Wei Zhang; Ajit S. Narang; Chen Mao
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Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death
Cell Death and Differentiation, ISSN: 14765403 13509047
Matthias Kist; László Kömüves; Tatiana Goncharov; Dugger; Charles Yu; Merone Roose-Girma; Kim Newton; Webster; Domagoj Vucic
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Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS
Cell Death and Differentiation, ISSN: 14765403 13509047
Sara L. Dominguez; Eugene Varfolomeev; Robert Brendza; Kimberly L. Stark; Joy S. Tea; Jose Imperio; Hai Ngu; Timothy K. Earr; Oded Foreman; Webster; Amy Easton; Domagoj Vucic; Baris Bingol
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Ultra-Response to Ranibizumab: Improvement by 4 or More Steps in Diabetic Retinopathy Severity in Diabetic Retinopathy Clinical Research Network Protocol S
Ophthalmology Retina, ISSN: 24686530
Allen Chiang; Sunir Garg; Michael A. Klufas; Allen C. Ho; Lauren Hill; Min Tsuboi; Ivaylo Stoilov
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Head-to-head comparison of DFO* and DFO chelators: selection of the best candidate for clinical 89Zr-immuno-PET
European Journal of Nuclear Medicine and Molecular Imaging, ISSN: 16197089 16197070
Marion Chomet; Maxime Schreurs; Maria J. Bolijn; Mariska Verlaan; Wissam Beaino; Kari Brown; Alex J. Poot; Albert D. Windhorst; Herman S. Gill; Jan Marik; Simon P. Williams; Joseph Cowell; Gilles Gasser; Thomas L. Mindt; Guus van Dongen; Daniëlle Vugts
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Comment on “Use of biomaterials for sustained delivery of anti-VEGF to treat retinal diseases”
Eye, ISSN: 14765454 0950222X
Peter A. Campochiaro; Giulio Barteselli
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Parameterization of Microsomal and Cytosolic Scaling Factors: Methodological and Biological Considerations for Scalar Derivation and Validation
European Journal of Drug Metabolism and Pharmacokinetics, ISSN: 21070180 03787966
Michael J. Doerksen; Robert S. Jones; Michael W. H. Coughtrie; Abby C. Collier
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Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion
Nature Genetics, ISSN: 15461718 10614036
Chris J. Frangieh; Johannes C. Melms; Pratiksha I. Thakore; Kathryn R. Geiger-Schuller; Patricia Ho; Adrienne M. Luoma; Brian Cleary; Livnat Jerby-Arnon; Shruti Malu; Michael S. Cuoco; Maryann Zhao; Casey R. Ager; Meri Rogava; Lila Hovey; Asaf Rotem; Chantale Bernatchez; Kai Wucherpfennig; Bruce E. Johnson; Orit Rozenblatt-Rosen; Dirk Schadendorf; Aviv Regev; Benjamin Izar
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Treatment Patterns, Disease Burden, and Outcomes in Patients with Giant Cell Arteritis and Polymyalgia Rheumatica: A Real-World, Electronic Health Record-Based Study of Patients in Clinical Practice
Rheumatology and Therapy, ISSN: 21986584 21986576
Gary Craig; Keith Knapp; Bob Salim; Shalini V. Mohan; Margaret Michalska
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Enrichment of circulating tumor-derived extracellular vesicles from human plasma
Journal of Immunological Methods, ISSN: 18727905 00221759
Kathryn E. Yoh; Christopher Lowe; Shilpi Mahajan; Rebecca Suttmann; Trung Nguy; Mike Reichelt; Jenny Yang; Rachel Melendez; Yijin Li; Luciana L. Molinero; Jane Ruppel; Wenfeng Xu; Vicki Plaks
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Computing the Hazard Ratios Associated With Explanatory Variables Using Machine Learning Models of Survival Data
JCO Clinical Cancer Informatics, ISSN: 24734276
Sameer Sundrani; James Lu
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Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Yixuan Zhou; Ingmar Niels Bastian; Mark D. Long; Michelle Dow; Weihua Li; Tao Liu; Rachael Katie Ngu; Laura Antonucci; Jian Yu Huang; Qui Phung; Xi-He Zhao; Sourav Banerjee; Xue-Jia Lin; Hongxia Wang; Brian Dang; Sylvia Choi; Daniel Karin; Hua Su; Mark H. Ellisman; Christina Jamieson; Marcus Bosenberg; Zhang Cheng; Johannes Haybaeck; Lukas Kenner; Kathleen M. Fisch; Richard Bourgon; Genevive Hernandez; Jennie R. Lill; Song Liu; Hannah Carter; Ira Mellman; Michael Karin; Shabnam Shalapour
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Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers
Developmental Cell, ISSN: 18781551 15345807
Eitan Erez Zahavi; Jessica J.A. Hummel; Yuhao Han; Citlali Bar; Riccardo Stucchi; Maarten Altelaar; Casper C Hoogenraad
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Updated Overall Survival and PD-L1 Subgroup Analysis of Patients With Extensive-Stage Small-Cell Lung Cancer Treated With Atezolizumab, Carboplatin, and Etoposide (IMpower133)
Journal of Clinical Oncology, ISSN: 15277755
Stephen V. Liu; Martin Reck; Mansfield; Tony Mok; Arnaud Scherpereel; Niels Reinmuth; Marina C. Garassino; Javier De Castro Carpeno; Califano; Makoto Nishio; Orlandi; Jorge Alatorre-Alexander; Leal; Ying Cheng; Jong-Seok Lee; Lam; Mark L. McCleland; Deng; See Phan; Leora Horn
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Tracking internal and external ions for constrained peptides leads to enhanced sequence coverage and disulfide bond deciphering
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Steven Chin; Tao Chen; Rami N. Hannoush; Christopher M. Crittenden
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Loss on Drying Using Halogen Moisture Analyzer: An Orthogonal Technique for Monitoring Volatile Content for In-Process Control Samples during Pharmaceutical Manufacturing
Organic Process Research and Development, ISSN: 1520586X 10836160
Sayyeda Zeenat A. Razvi; Isabelle Kamm; Nguyen; Jackson D. Pellett; Archana Kumar
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Tissue regeneration: Reserve or reverse?
Science, ISSN: 10959203 00368075
Ramesh A. Shivdasani; Hans Clevers; Frederic J. De Sauvage
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Loss on Drying Using Halogen Moisture Analyzer: An Orthogonal Technique for Monitoring Volatile Content for In-Process Control Samples during Pharmaceutical Manufacturing
Organic Process Research and Development, ISSN: 1520586X 10836160
Sayyeda Zeenat A. Razvi; Isabelle Kamm; Tina Nguyen; Jackson D. Pellett; Archana Kumar
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Transcriptional Subtypes Resolve Tumor Heterogeneity and Identify Vulnerabilities to MEK Inhibition in Lung Adenocarcinoma
Clinical Cancer Research, ISSN: 15573265 10780432
Anneleen Daemen; Jonathan Cooper; Szymon Myrta; Matthew Wongchenko; Eva Lin; Jason E. Long; Oded Foreman; Zora Modrusan; Jarrod Tremayne; Cecile C. de la Cruz; Mark Merchant; Scott E. Martin; Yibing Yan; Melissa Junttila
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Atezolizumab for PD-L1-Selected Patients with NSCLC. Reply
New England Journal of Medicine, ISSN: 15334406
Roy S. Herbst; Hiroshi Kuriki; David Spigel
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Exploring Human Skin Aging at the Single-Cell Level
Developmental Cell, ISSN: 18781551 15345807
Mary Mohrin; Heinrich Jasper
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Multi-dimensional LC-MS: The next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches
Analyst, ISSN: 13645528 00032654
Julien Camperi; Alexandre Goyon; Davy Guillarme; Kelly Zhang; Cinzia Stella
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Simultaneous quantitation of water and residual solvents in pharmaceuticals by rapid headspace gas chromatography with thermal conductivity detection (GC-TCD)
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Jacob Kay; Rekha Thomas; Jason Gruenhagen; Venkatramani
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A phase 2 study of venetoclax plus R-CHOP as first-line treatment for patients with diffuse large B-cell lymphoma
Blood, ISSN: 15280020 00064971
Morschhauser; Pierre Feugier; Ian W. Flinn; Robin Gasiorowski; Greil; Illés; Nathalie A. Johnson; Jean-François Larouche; Pieternella J. Lugtenburg; Caterina Patti; Gilles Salles; Marek Trneny; Sven De Vos; Farheen Mir; Divya Samineni; Su Young Kim; Yanwen Jiang; Elizabeth A. Punnoose; Arijit Sinha; Emma Clark; Nathalie Spielewoy; Kathryn Humphrey; Alexandra Bazeos; Zelenetz
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Personalized Cancer Vaccines: Clinical Landscape, Challenges, and Opportunities
Molecular Therapy, ISSN: 15250024 15250016
Colby S. Shemesh; Joy C. Hsu; Iraj Hosseini; Shen; Rotte; Patrick S. Twomey; Sandhya Girish; Benjamin Wu
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OCRE Domains of Splicing Factors RBM5 and RBM10: Tyrosine Ring-Flip Frequencies Determined by Integrated Use of 1H NMR Spectroscopy and Molecular Dynamics Simulations
ChemBioChem, ISSN: 14397633 14394227
Bryan T. Martin; Robert D. Malmstrom; Rommie E. Amaro; Kurt Wüthrich
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An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease
European Journal of Human Genetics, ISSN: 14765438 10184813
Sanni E. Ruotsalainen; Juulia J. Partanen; Anna Cichonska; Jake Lin; Christian Benner; Ida Surakka; Howard Jacob; Sally John; Robert M. Plenge; Mark I. McCarthy; Caroline Fox; Kathy Call; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Anne Pitkäranta; Riitta Kaarteenaho; Urho Kujala; Jimmy Liu; Shameek Biswas; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Klinger; Matthias Gossel; Johanna Schleutker; Markus Perola; Mikko Arvas; Olli Carpen; Reetta Hinttala; Reijo Laaksonen; Arto Mannermaa; Juha Paloneva; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Sahar Esmaeeli; Susan Eaton; Sanni Lahdenperä; Geoffrey A. Kerchner; Natalie Bowers; Edmond Teng; John Eicher; Padhraig Gormley; Kari Linden; Christopher D. Whelan; Fanli Xu; David Pulford; Martti Färkkilä; Sampsa Pikkarainen; Airi Jussila; Timo Blomster; Mikko Kiviniemi; Markku Voutilainen; Graham Heap; Keith Usiskin; Tim Lu; Danny Oh; Xinli Hu; Linda McCarthy; Kari Eklund; Antti Palomäki; Pia Isomäki; Laura Pirilä; Oili Kaipiainen-Seppänen; Johanna Huhtakangas; Bob Georgantas; Apinya Lertratanakul; Marla Hochfeld; Nan Bing; Xinli Hu; Jorge Esparza Gordillo; Nina Mars; Margit Pelkonen; Paula Kauppi; Hannu Kankaanranta; Terttu Harju; David Close; Steven Greenberg; Hubert Chen; Jo Betts; Soumitra Ghosh; Veikko Salomaa; Teemu Niiranen; Markus Juonala; Kaj Metsärinne; Mika Kähönen; Juhani Junttila; Markku Laakso; Jussi Pihlajamäki; Juha Sinisalo; Marja-Riitta Taskinen; Tiinamaija Tuomi; Jari Laukkanen; Ben Challis; Andrew S. Peterson; Audrey Y. Chu; Jaakko Parkkinen; Melissa Miller; Anthony Muslin; Heikki Joensuu; Tuomo Meretoja; Lauri Aaltonen; Annika Auranen; Peeter Karihtala; Saila Kauppila; Päivi Auvinen; Elenius; Relja Popovic; Jeff Waring; Athena Matakidou; Jennifer L. Schutzman; Andrey Loboda; Aparna Chhibber; Heli Lehtonen; Stefan McDonough; Marika Crohns; Diptee Kulkarni; Kai Kaarniranta; Joni A. Turunen; Terhi Ollila; Sanna Seitsonen; Hannu Uusitalo; Vesa Aaltonen; Hannele Uusitalo-Järvinen; Marja Luodonpää; Nina Hautala; Heiko Runz; Erich C. Strauss; Hao Chen; Anna Podgornaia; Vinay Mehta; Joshua Hoffman; Kaisa Tasanen; Laura Huilaja; Katariina Hannula-Jouppi; Teea Salmi; Sirkku Peltonen; Leena Koulu; Ilkka Harvima; Kirsi Kalpala; Ying Wu; David Choy; John Michon; Nizar Smaoui; Fedik Rahimov; Anne Lehtonen; Dawn Waterworth; Risto Kajanne; Ulrike Lyhs; Mari Kaunisto; Justin Wade Davis; Bridget Riley-Gillis; Danjuma Quarless; Slavé Petrovski; Jimmy Liu; Chia-Yen Chen; Paola G. Bronson; Robert Yang; Joseph Maranville; Diana Chang; Julie Hunkapiller; Tushar Bhangale; Dorothée Diogo; Emily Holzinger; Padhraig Gormley; Xulong Wang; Xing Chen; Åsa Hedman; Kirsi Auro; Clarence Wang; Ethan Xu; Franck Auge; Clement Chatelain; Mitja Kurki; Juha Karjalainen; Aki S. Havulinna; Anu Jalanko; Kimmo Palin; Pietro della Briotta Parolo; Wei Zhou; Manuel Rivas; Aarno Palotie; Arto Lehisto; Andrea Ganna; Vincent Llorens; Antti Karlsson; Kati Hyvärinen; Jarmo Ritari; Tiina Wahlfors; Miika Koskinen; Johannes Kettunen; Katri Pylkäs; Marita Kalaoja; Minna Karjalainen; Tuomo Mantere; Eeva Kangasniemi; Sami Heikkinen; Arto Mannermaa; Eija Laakkonen; Juha Kononen; Anu Loukola; Päivi Laiho; Tuuli Sistonen; Essi Kaiharju; Markku Laukkanen; Elina Järvensivu; Sini Lähteenmäki; Lotta Männikkö; Regis Wong; Kati Kristiansson; Hannele Mattsson; Tero Hiekkalinna; Manuel González Jiménez; Kati Donner; Kalle Pärn; Javier Nunez-Fontarnau; Jarmo Harju; Elina Kilpeläinen; Georg Brein; Alexander Dada; Ghazal Awaisa; Anastasia Shcherban; Timo P. Sipilä; Hannele Laivuori; Susanna Lemmelä; Tuomo T. J. Kiiskinen; Tarja Laitinen; Harri Siirtola; Javier Gracia Tabuenca; Lila Kallio; Sirpa Soini; Jukka Partanen; Kimmo Pitkänen; Seppo Vainio; Kimmo Savinainen; Veli-Matti Kosma; Teijo Kuopio; Mary Pat Reeve; Priit Palta; Marko Salmi; Sirpa Jalkanen; Ari Ahola-Olli; Aarno Palotie; Veikko Salomaa; Mark J. Daly; Matti Pirinen; Samuli Ripatti; Jukka Koskela
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Neurodegeneration, gliosis, and resolution of haemorrhage in neovascular age-related macular degeneration, a clinicopathologic correlation
Eye, ISSN: 14765454 0950222X
Miaoling Li; Rosa Dolz-Marco; Jeffrey D. Messinger; Daniela Ferrara; K. Bailey Freund; Christine A. Curcio
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Randomized Trial of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF-Mutant Metastatic Colorectal Cancer (SWOG S1406)
Journal of Clinical Oncology, ISSN: 15277755
Scott Kopetz; Katherine A. Guthrie; Van Morris; Heinz-Josef Lenz; Anthony Magliocco; Dipen Maru; Yibing Yan; Richard Lanman; Ganiraju Manyam; David Hong; Alexey V. Sorokin; Chloe E. Atreya; Luis A. Diaz; Carmen Allegra; Kanwal Pratap Singh Raghav; Stephen E. Wang; Christopher H. Lieu; Shannon L. McDonough; Philip A. Philip; Hochster
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Impact of delayed time to treatment on visual outcomes in neovascular AMD: Data from the harbor study
Ophthalmic Surgery Lasers and Imaging Retina, ISSN: 23258179 23258160
Roger A. Goldberg; Lauren Hill; Tatiana Davis; Carlos Quezada Ruiz
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Extracellular BMP1 is the major proteinase for COOH-terminal proteolysis of type I procollagen in lung fibroblasts
American Journal of Physiology - Cell Physiology, ISSN: 15221563 03636143
Elsa-Noah N’Diaye; Ryan Cook; Hua Wang; Ping Wu; Ryan LaCanna; Cong Wu; Zhengmao Ye; Dhaya Seshasayee; Meredith Hazen; Wei Yu Lin; Tulika Tyagi; Isidro Hötzel; Lucinda Tam; Robert J. Newman; Merone Roose-Girma; Paul J. Wolters; Ning Ding
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Characterization of robust immune responses to a bispecific antibody, a novel class of antibody therapeutics
Bioanalysis, ISSN: 17576199 17576180
Kun Peng; Ketevan A. Siradze; Saloumeh Kadkhodayan Fischer
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2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome (Part 1 - Recommendations on Industry/Regulators Consensus on BMV of Biotherapeutics by LCMS, Advanced Application in Hybrid Assays, Regulatory Challenges in Mass Spec, Innovation in Small Molecules, Peptides and Oligos)
Bioanalysis, ISSN: 17576199 17576180
Hendrik Neubert; Stephen C. Alley; Anita Lee; Wenying Jian; Michael H. Buonarati; Anna Edmison; Fabio Garofolo; Boris Gorovits; Sam Haidar; Bill Mylott; Parya Nouri; Mark Qian; Stephen Vinter; Voelker; Jan Welink; Jiang Wu; Eric Yang; Hongbin Yu; Christopher Evans; Scott Summerfield; Jian Wang; Kevin Bateman; Jason Boer; Brian J. Dean; Lieve Dillen; Patrick Faustino; Luca Ferrari; Nicola Hughes; Lina Luo; Timothy Olah; Noah Post; Spellman; Jens Sydor; Hui Zhang; Jenny Zhang; Jinhui Zhang; Christine Fandozzi; Amanda Wilson; Daniela Fraier; Chris Beaver; Suman Dandamudi; Arindam Dasgupta; Rebecca Elliott; Allena Ji; Wenkui Li; Michael McGuinness; Gustavo Mendes Lima Santos; Tahseen Mirza; Natasha Savoie; Diaa Shakleya; Sune Sporring; Susan Stojdl; Phillip Sundman; Nilufer Tampal; Eric Woolf
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Phase 2 trial to assess lebrikizumab in patients with idiopathic pulmonary fibrosis
European Respiratory Journal, ISSN: 13993003 09031936
Toby M. Maher; Ulrich Costabel; Marilyn K Glassberg; Yasuhiro Kondoh; Takashi Ogura; Mary Beth Scholand; David Kardatzke; Monet Howard; Julie Olsson; Margaret Neighbors; Paula Belloni; Jeffrey J. Swigris
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An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease
European Journal of Human Genetics, ISSN: 14765438 10184813
Sanni E. Ruotsalainen; Juulia J. Partanen; Anna Cichonska; Jake Lin; Christian Benner; Ida Surakka; Mark J. Daly; Howard Jacob; Sally John; Robert M. Plenge; Mark I. McCarthy; Caroline Fox; Kathy Call; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Anne Pitkäranta; Riitta Kaarteenaho; Urho Kujala; Jimmy Liu; Shameek Biswas; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Klinger; Matthias Gossel; Johanna Schleutker; Markus Perola; Mikko Arvas; Olli Carpen; Reetta Hinttala; Reijo Laaksonen; Arto Mannermaa; Juha Paloneva; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Sahar Esmaeeli; Susan Eaton; Sanni Lahdenperä; Geoffrey A. Kerchner; Natalie Bowers; Edmond Teng; John Eicher; Vinay Mehta; Padhraig Gormley; Kari Linden; Christopher D. Whelan; Fanli Xu; David Pulford; Martti Färkkilä; Sampsa Pikkarainen; Airi Jussila; Timo Blomster; Mikko Kiviniemi; Markku Voutilainen; Graham Heap; Keith Usiskin; Tim Lu; Danny Oh; Vinay Mehta; Melissa Miller; Xinli Hu; Linda McCarthy; Kari Eklund; Antti Palomäki; Pia Isomäki; Laura Pirilä; Oili Kaipiainen-Seppänen; Johanna Huhtakangas; Bob Georgantas; Apinya Lertratanakul; Marla Hochfeld; Vinay Mehta; Nan Bing; Xinli Hu; Jorge Esparza Gordillo; Nina Mars; Margit Pelkonen; Paula Kauppi; Hannu Kankaanranta; Terttu Harju; David Close; Steven Greenberg; Hubert Chen; Vinay Mehta; Jo Betts; Soumitra Ghosh; Veikko Salomaa; Teemu Niiranen; Markus Juonala; Kaj Metsärinne; Mika Kähönen; Juhani Junttila; Markku Laakso; Jussi Pihlajamäki; Juha Sinisalo; Marja-Riitta Taskinen; Tiinamaija Tuomi; Jari Laukkanen; Ben Challis; Andrew S. Peterson; Audrey Y. Chu; Vinay Mehta; Jaakko Parkkinen; Melissa Miller; Anthony Muslin; Heikki Joensuu; Tuomo Meretoja; Lauri Aaltonen; Annika Auranen; Peeter Karihtala; Saila Kauppila; Päivi Auvinen; Elenius; Relja Popovic; Jeff Waring; Athena Matakidou; Jennifer L. Schutzman; Vinay Mehta; Andrey Loboda; Aparna Chhibber; Heli Lehtonen; Stefan McDonough; Marika Crohns; Diptee Kulkarni; Kai Kaarniranta; Joni A. Turunen; Terhi Ollila; Sanna Seitsonen; Hannu Uusitalo; Vesa Aaltonen; Hannele Uusitalo-Järvinen; Marja Luodonpää; Nina Hautala; Heiko Runz; Erich C. Strauss; Hao Chen; Anna Podgornaia; Vinay Mehta; Joshua Hoffman; Kaisa Tasanen; Laura Huilaja; Katariina Hannula-Jouppi; Teea Salmi; Sirkku Peltonen; Leena Koulu; Ilkka Harvima; Kirsi Kalpala; Ying Wu; David Choy; John Michon; Nizar Smaoui; Fedik Rahimov; Anne Lehtonen; Dawn Waterworth; Risto Kajanne; Ulrike Lyhs; Mari Kaunisto; Justin Wade Davis; Bridget Riley-Gillis; Danjuma Quarless; Slavé Petrovski; Jimmy Liu; Chia-Yen Chen; Paola G. Bronson; Robert Yang; Joseph Maranville; Diana Chang; Julie Hunkapiller; Tushar Bhangale; Dorothée Diogo; Emily Holzinger; Padhraig Gormley; Xulong Wang; Xing Chen; Åsa Hedman; Kirsi Auro; Clarence Wang; Ethan Xu; Franck Auge; Clement Chatelain; Mitja Kurki; Mark Daly; Juha Karjalainen; Aki S. Havulinna; Anu Jalanko; Kimmo Palin; Pietro della Briotta Parolo; Wei Zhou; Manuel Rivas; Aarno Palotie; Arto Lehisto; Andrea Ganna; Vincent Llorens; Antti Karlsson; Kati Hyvärinen; Jarmo Ritari; Tiina Wahlfors; Miika Koskinen; Johannes Kettunen; Katri Pylkäs; Marita Kalaoja; Minna Karjalainen; Tuomo Mantere; Eeva Kangasniemi; Sami Heikkinen; Arto Mannermaa; Eija Laakkonen; Juha Kononen; Anu Loukola; Päivi Laiho; Tuuli Sistonen; Essi Kaiharju; Markku Laukkanen; Elina Järvensivu; Sini Lähteenmäki; Lotta Männikkö; Regis Wong; Kati Kristiansson; Hannele Mattsson; Tero Hiekkalinna; Manuel González Jiménez; Kati Donner; Kalle Pärn; Javier Nunez-Fontarnau; Jarmo Harju; Elina Kilpeläinen; Georg Brein; Alexander Dada; Ghazal Awaisa; Anastasia Shcherban; Timo P. Sipilä; Hannele Laivuori; Susanna Lemmelä; Tuomo T. J. Kiiskinen; Tarja Laitinen; Harri Siirtola; Javier Gracia Tabuenca; Lila Kallio; Sirpa Soini; Jukka Partanen; Kimmo Pitkänen; Seppo Vainio; Kimmo Savinainen; Veli-Matti Kosma; Teijo Kuopio; Mary Pat Reeve; Priit Palta; Marko Salmi; Sirpa Jalkanen; Ari Ahola-Olli; Aarno Palotie; Veikko Salomaa; Mark Daly; Matti Pirinen; Samuli Ripatti; Jukka Koskela
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Improving cryo-EM structure validation
Nature Methods, ISSN: 15487105
Alexis Rohou
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NRF2 Activation promotes aggressive lung cancer and associates with poor clinical outcomes
Clinical Cancer Research, ISSN: 15573265 10780432
Anju Singh; Anneleen Daemen; Dorothee Nickles; Sang-Min Jeon; Oded Foreman; Kuladeep Sudini; Florian Gnad; Stephane Lajoie; Naina Gour; Wayne Mitzner; Samit Chatterjee; Eun-Ji Choi; Buvana Ravishankar; Amy Rappaport; Namrata S. Patil; Mark L. McCleland; Leisa Johnson; George Acquaah-Mensah; Edward Gabrielson; Shyam Biswal; Georgia Hatzivassiliou
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An anti–CD22-seco-CBI-dimer antibody–drug conjugate (ADC) for the treatment of non-hodgkin lymphoma that provides a longer duration of response than auristatin-based ADCs in preclinical models
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Shang-Fan Yu; Donna W. Lee; Bing Zheng; Geoffrey Del Rosario; Douglas Leipold; Helen Booler; Fiona Zhong; Montserrat Carrasco-Triguero; Kyu Hong; Peter Yan; Rebecca K. Rowntree; Melissa Schutten; Thomas H. Pillow; Jack D. Sadowsky; Peter Dragovich; Andrew G. Polson
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Few-shot learning creates predictive models of drug response that translate from high-throughput screens to individual patients
Nature Cancer, ISSN: 26621347
Jianzhu Ma; Samson H. Fong; Yunan Luo; Christopher J. Bakkenist; John Paul Shen; Soufiane Mourragui; Lodewyk F. A. Wessels; Marc Hafner; Roded Sharan; Jian Peng; Trey Ideker
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Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes
Nature Immunology, ISSN: 15292916 15292908
Elijah Willie; Hugo Schmutz; Jodie Chandler; Alexandra Schnell; Pratiksha I. Thakore; Graham LeGros; Sara Mostafavi; Mathis; Christophe Benoist; Oscar Aguilar; Rhys Allan; Jillian L. Astarita; K Frank Austen; Nora A. Barrett; Alev Baysoy; Christophe Benoist; Brian Brown; Matthew B. Buechler; Jason D. Buenrostro; Maria Acebes Casanova; Kyunghee Choi; Kaitavjeet Chowdhary; Marco Colonna; Ty Crowl; Tianda Deng; Jigar V. Desai; Fiona Desland; Maxime Dhainaut; Jiarui Ding; Claudia X. Dominguez; Daniel F. Dwyer; Michela Frascoli; Shani Gal-Oz; Ananda Goldrath; Ricardo Grieshaber-Bouyer; Baosen Jia; Tim Johanson; Stefan Jordan; Joonsoo Kang; Varun N. Kapoor; Ephriam Kenigsberg; Joel Kim; Ki wook Kim; Evgeny Kiner; Mitchell Kronenberg; Lewis L. Lanier; Catherine Laplace; Caleb A. Lareau; Andrew Leader; Jisu Lee; Assaf Magen; Barbara Maier; Alexandra Maslova; Diane Mathis; Adelle McFarland; Miriam Merad; Etienne Meunier; Monach; Sara Mostafavi; Sören Müller; Christoph Muus; Hadas Ner-Gaon; Quyhn Nguyen; Peter A. Nigrovic; German Novakovsky; Stephen L. Nutt; Kayla Omilusik; Adriana Ortiz-Lopez; Mallory Paynich; Vincent Peng; Marc Potempa; Rachana Pradhan; Sara Quon; Ricardo N. Ramirez; Deepshika Ramanan; Gwendalyn J. Randolph; Aviv Regev; Samuel A. Rose; Kumba Seddu; Tal Shay; Avishai Shemesh; Justin A. Shyer; Christopher Smilie; Nick Spidale; Ayshwarya Subramanian; Katelyn Sylvia; Julie Tellier; Shannon J. Turley; Brinda Vijaykumar; Amy Wagers; Chendi Wang; Peter L. Wang; Aleksandra Wroblewska; Liang Yang; Aldrin Yim; Hideyuki Yoshida
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Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Nature Medicine, ISSN: 1546170X 10788956
Livnat Jerby-Arnon; Cyril Neftel; Marni E. Shore; Hannah R. Weisman; Nathan D. Mathewson; Matthew J. McBride; Brian Haas; Benjamin Izar; Angela Volorio; Gaylor Boulay; Luisa Cironi; Alyssa R. Richman; Liliane C. Broye; Joseph M. Gurski; Christina C. Luo; Ravindra Mylvaganam; Lan Nguyen; Shaolin Mei; Johannes C. Melms; Christophe Georgescu; Ofir Cohen; Jorge E. Buendia-Buendia; Asa Segerstolpe; Malika Sud; Michael S. Cuoco; Danny Labes; Simon Gritsch; Daniel R. Zollinger; Nicole Ortogero; Joseph M. Beechem; Petur Nielsen; Ivan Chebib; Tu Nguyen-Ngoc; Michael Montemurro; Gregory M. Cote; Edwin Choy; Igor Letovanec; Stéphane Cherix; Nikhil Wagle; Peter K. Sorger; Alex B. Haynes; John T. Mullen; Ivan Stamenkovic; Miguel N. Rivera; Cigall Kadoch; Kai W. Wucherpfennig; Orit Rozenblatt-Rosen; Mario L. Suvà; Nicolò Riggi; Aviv Regev
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Ubiquitination in the regulation of inflammatory cell death and cancer
Cell Death and Differentiation, ISSN: 14765403 13509047
Peter E. Cockram; Matthias Kist; Sumit Prakash; Si-Han Chen; Ingrid E. Wertz; Domagoj Vucic
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NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity
Nature Immunology, ISSN: 15292916 15292908
Meidi Gu; Xiaofei Zhou; Jee Hyung Sohn; Lele Zhu; Zuliang Jie; Jin-Young Yang; Xiaofeng Zheng; Xiaoping Xie; Jie Yang; Yaoyao Shi; Hans D. Brightbill; Jae Bum Kim; Jing Wang; Xuhong Cheng; Shao-Cong Sun
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Changes in Treatment-Naive Pigment Epithelial Detachments Associated with the Initial Anti-Vascular Endothelial Growth Factor Injection: A Post Hoc Analysis from the HARBOR Trial
JAMA Ophthalmology, ISSN: 21686173 21686165
Michael Javaheri; Lauren Hill; Avanti Ghanekar; Ivaylo Stoilov
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Psychometric Properties of the Clinical Dementia Rating — Sum of Boxes and other Cognitive and Functional Outcomes in a Prodromal Alzheimer’s Disease Population
Journal of Prevention of Alzheimer's Disease, ISSN: 24260266 22745807
Fiona McDougall; Edgar; Mertes; Paul Delmar; Fontoura; Danielle Abi-Saab; Lansdall; Mercè Boada; Rachelle S. Doody
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Phase III randomized study of taselisib or placebo with fulvestrant in estrogen receptor-positive, PIK3CA-mutant, HER2-negative, advanced breast cancer: the SANDPIPER trial
Annals of Oncology, ISSN: 15698041 09237534
Susan Dent; Javier Cortés; Im; Diéras; Nadia Harbeck; Ian E. Krop; Wilson; Na Cui; Frauke Schimmoller; Jerry Y. Hsu; Jing He; De Laurentiis; Sousa; Drullinsky; William Jacot
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Adolescent boys with constitutional delay of growth and puberty grow faster than patients with organic growth hormone deficiency
Clinical Endocrinology, ISSN: 13652265 03000664
Gerhard Binder; Theresa J. Lehrian; Elisa Hoffmann; Gunnar Blumenstock; Abdelkader Rahmaoui; Benjamin L. Trzaskoma; Thomas Reinehr
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