Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 2401 - 2450 OF 15217 RESULTS

Analysis of Spatial Organization of Suppressive Myeloid Cells and Effector T Cells in Colorectal Cancer—A Potential Tool for Discovering Prognostic Biomarkers in Clinical Research
Frontiers in Immunology, ISSN: 16643224
Natalie Zwing; Henrik Failmezger; Chia-Huey Ooi; Derrek P. Hibar; Marta Cañamero; Bruno Gomes; Fabien Gaire; Konstanty Korski
View on Scopus
Toward a Better Understanding of Bioassays for the Development of Biopharmaceuticals by Exploring the Structure-Antibody-Dependent Cellular Cytotoxicity Relationship in Human Primary Cells
Frontiers in Immunology, ISSN: 16643224
Sébastien Wieckowski; Cécile Avenal; Arturo V. Orjalo; Daniel Gygax; Florian Cymer
View on Scopus
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
Nature, ISSN: 14764687 00280836
Erik L. Bao; Satish K. Nandakumar; Xiaotian Liao; Alexander G. Bick; Marcin Tabaka; Olga I. Gan; Aki S. Havulinna; Caleb A. Lareau; Aitzkoa L. de Lapuente Portilla; Bo Li; Connor Emdin; Veryan Codd; Christopher P. Nelson; Christopher J. Walker; Claire Churchhouse; Albert de la Chapelle; Daryl E. Klein; Björn Nilsson; Peter W. F. Wilson; Kelly Cho; Saiju Pyarajan; J. Michael Gaziano; Nilesh J. Samani; Mark Daly; Howard Jacob; Sally John; Robert M. Plenge; Mark I. McCarthy; Caroline Fox; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Jukka Partanen; Anne Pitkäranta; Riitta Kaarteenaho; Urho Kujala; Jimmy Liu; Shameek Biswas; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Call; Kathy Klinger; Matthias Gossel; Johanna Schleutker; Markus Perola; Mikko Arvas; Reetta Hinttala; Reijo Laaksonen; Arto Mannermaa; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Sahar Esmaeeli; Susan Eaton; Sanni Lahdenperä; Janet van Adelsberg; Shameek Biswas; Geoffrey A. Kerchner; Edmond Teng; John Eicher; Vinay Mehta; Padhraig Gormley; Kari Linden; Christopher D. Whelan; Fanli Xu; David Pulford; Martti Färkkilä; Sampsa Pikkarainen; Airi Jussila; Timo Blomster; Mikko Kiviniemi; Markku Voutilainen; Graham Heap; Keith Usiskin; Tim Lu; Danny Oh; Vinay Mehta; Melissa Miller; Xinli Hu; Linda McCarthy; Kari Eklund; Antti Palomäki; Pia Isomäki; Laura Pirilä; Oili Kaipiainen-Seppänen; Johanna Huhtakangas; Bob Georgantas; Apinya Lertratanakul; Marla Hochfeld; Vinay Mehta; Nan Bing; Xinli Hu; Jorge Esparza Gordillo; Nina Mars; Margit Pelkonen; Paula Kauppi; Hannu Kankaanranta; Terttu Harju; David Close; Steven Greenberg; Hubert Chen; Vinay Mehta; Jo Betts; Soumitra Ghosh; Veikko Salomaa; Teemu Niiranen; Markus Juonala; Kaj Metsärinne; Mika Kähönen; Juhani Junttila; Markku Laakso; Jussi Pihlajamäki; Juha Sinisalo; Marja-Riitta Taskinen; Tiinamaija Tuomi; Jari Laukkanen; Ben Challis; Andrew S. Peterson; Audrey Y. Chu; Vinay Mehta; Jaakko Parkkinen; Melissa Miller; Anthony Muslin; Heikki Joensuu; Tuomo Meretoja; Lauri Aaltonen; Annika Auranen; Peeter Karihtala; Saila Kauppila; Päivi Auvinen; Elenius; Relja Popovic; Jeff Waring; Athena Matakidou; Jennifer L. Schutzman; Vinay Mehta; Andrey Loboda; Aparna Chhibber; Heli Lehtonen; Stefan McDonough; Marika Crohns; Diptee Kulkarni; Kai Kaarniranta; Joni A. Turunen; Terhi Ollila; Sanna Seitsonen; Hannu Uusitalo; Vesa Aaltonen; Hannele Uusitalo-Järvinen; Marja Luodonpää; Nina Hautala; Heiko Runz; Erich C. Strauss; Hao Chen; Anna Podgornaia; Vinay Mehta; Joshua Hoffman; Kaisa Tasanen; Laura Huilaja; Katariina Hannula-Jouppi; Teea Salmi; Sirkku Peltonen; Leena Koulu; Ilkka Harvima; Kirsi Kalpala; Ying Wu; David Choy; John Michon; Nizar Smaoui; Fedik Rahimov; Anne Lehtonen; Dawn Waterworth; Justin Wade Davis; Bridget Riley-Gillis; Danjuma Quarless; Slavé Petrovski; Jimmy Liu; Chia-Yen Chen; Paola G. Bronson; Robert Yang; Joseph Maranville; Shameek Biswas; Diana Chang; Julie Hunkapiller; Tushar Bhangale; Natalie Bowers; Dorothée Diogo; Emily Holzinger; Padhraig Gormley; Xulong Wang; Xing Chen; Åsa Hedman; Kirsi Auro; Clarence Wang; Ethan Xu; Franck Auge; Clement Chatelain; Samuli Ripatti; Mark J. Daly; Kimmo Palin; Pietro della Briotta Parolo; Wei Zhou; Manuel Rivas; Aarno Palotie; Andrea Ganna; Vincent Llorens; Antti Karlsson; Mikko Arvas; Kati Hyvärinen; Jarmo Ritari; Tiina Wahlfors; Miika Koskinen; Olli Carpen; Johannes Kettunen; Katri Pylkäs; Marita Kalaoja; Minna Karjalainen; Tuomo Mantere; Eeva Kangasniemi; Sami Heikkinen; Arto Mannermaa; Eija Laakkonen; Juha Kononen; Lila Kallio; Sirpa Soini; Jukka Partanen; Kimmo Pitkänen; Seppo Vainio; Kimmo Savinainen; Veli-Matti Kosma; Teijo Kuopio; Anu Jalanko; Risto Kajanne; Ulrike Lyhs; Mitja Kurki; Juha Karjalainen; Pietro della Briotta Parola; Sina Rüeger; Arto Lehisto; Wei Zhou; Masahiro Kanai; Hannele Laivuori; Tuomo T. J. Kiiskinen; Mari Kaunisto; Jarmo Harju; Elina Kilpeläinen; Georg Brein; Oluwaseun A. Dada; Ghazal Awaisa; Anastasia Shcherban; Timo P. Sipilä; Kati Donner; Anu Loukola; Päivi Laiho; Tuuli Sistonen; Essi Kaiharju; Markku Laukkanen; Elina Järvensivu; Sini Lähteenmäki; Lotta Männikkö; Regis Wong; Hannele Mattsson; Kati Kristiansson; Susanna Lemmelä; Tero Hiekkalinna; Manuel González Jiménez; Priit Palta; Kalle Pärn; Javier Nunez-Fontarnau; Tarja Laitinen; Harri Siirtola; Javier Gracia Tabuenca; Michelle Agee; Babak Alipanahi; Adam Auton; Robert K. Bell; Katarzyna Bryc; Sarah L. Elson; Pierre Fontanillas; Nicholas A. Furlotte; David Hinds; Karen E. Huber; Aaron Kleinman; Nadia K. Litterman; Jennifer C. McCreight; Matthew H. McIntyre; Joanna L. Mountain; Elizabeth S. Noblin; Carrie A.M. Northover; Steven Pitts; J. Fah Sathirapongsasuti; Olga V. Sazonova; Janie F. Shelton; Suyash Shringarpure; Tian; Joyce Y. Tung; Vladimir Vacic; Catherine H. Wilson; Aviv Regev; Aarno Palotie; Neale; John E. Dick; Pradeep Natarajan; Christopher J. O’Donnell; Mark Daly; Michael Milyavsky; Sekar Kathiresan; Vijay G. Sankaran
View on Scopus
A fit for purpose synthesis of Bruton's tyrosine kinase inhibitor GDC-0852
Tetrahedron Letters, ISSN: 18733581 00404039
Ngiap-Kie Lim; Haiming Zhang; C. Gregory Sowell; Francis Gosselin
View on Scopus
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
Nature, ISSN: 14764687 00280836
Erik L. Bao; Satish K. Nandakumar; Xiaotian Liao; Alexander G. Bick; Marcin Tabaka; Olga I. Gan; Aki S. Havulinna; Caleb A. Lareau; Aitzkoa L. de Lapuente Portilla; Bo Li; Connor Emdin; Veryan Codd; Christopher P. Nelson; Christopher J. Walker; Claire Churchhouse; Albert de la Chapelle; Daryl E. Klein; Björn Nilsson; Peter W. F. Wilson; Kelly Cho; Saiju Pyarajan; J. Michael Gaziano; Nilesh J. Samani; Howard Jacob; Sally John; Robert M. Plenge; Mark I. McCarthy; Caroline Fox; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Jukka Partanen; Anne Pitkäranta; Riitta Kaarteenaho; Urho Kujala; Jimmy Liu; Shameek Biswas; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Call; Kathy Klinger; Matthias Gossel; Johanna Schleutker; Markus Perola; Mikko Arvas; Reetta Hinttala; Reijo Laaksonen; Arto Mannermaa; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Sahar Esmaeeli; Susan Eaton; Sanni Lahdenperä; Janet van Adelsberg; Shameek Biswas; Geoffrey A. Kerchner; Edmond Teng; John Eicher; Padhraig Gormley; Kari Linden; Christopher D. Whelan; Fanli Xu; David Pulford; Martti Färkkilä; Sampsa Pikkarainen; Airi Jussila; Timo Blomster; Mikko Kiviniemi; Markku Voutilainen; Graham Heap; Keith Usiskin; Tim Lu; Danny Oh; Melissa Miller; Xinli Hu; Linda McCarthy; Kari Eklund; Antti Palomäki; Pia Isomäki; Laura Pirilä; Oili Kaipiainen-Seppänen; Johanna Huhtakangas; Bob Georgantas; Apinya Lertratanakul; Marla Hochfeld; Nan Bing; Xinli Hu; Jorge Esparza Gordillo; Nina Mars; Margit Pelkonen; Paula Kauppi; Hannu Kankaanranta; Terttu Harju; David Close; Steven Greenberg; Hubert Chen; Jo Betts; Soumitra Ghosh; Veikko Salomaa; Teemu Niiranen; Markus Juonala; Kaj Metsärinne; Mika Kähönen; Juhani Junttila; Markku Laakso; Jussi Pihlajamäki; Juha Sinisalo; Marja-Riitta Taskinen; Tiinamaija Tuomi; Jari Laukkanen; Ben Challis; Andrew S. Peterson; Audrey Y. Chu; Jaakko Parkkinen; Melissa Miller; Anthony Muslin; Heikki Joensuu; Tuomo Meretoja; Lauri Aaltonen; Annika Auranen; Peeter Karihtala; Saila Kauppila; Päivi Auvinen; Elenius; Relja Popovic; Jeff Waring; Athena Matakidou; Jennifer L. Schutzman; Andrey Loboda; Aparna Chhibber; Heli Lehtonen; Stefan McDonough; Marika Crohns; Diptee Kulkarni; Kai Kaarniranta; Joni A. Turunen; Terhi Ollila; Sanna Seitsonen; Hannu Uusitalo; Vesa Aaltonen; Hannele Uusitalo-Järvinen; Marja Luodonpää; Nina Hautala; Heiko Runz; Erich C. Strauss; Hao Chen; Anna Podgornaia; Vinay Mehta; Joshua Hoffman; Kaisa Tasanen; Laura Huilaja; Katariina Hannula-Jouppi; Teea Salmi; Sirkku Peltonen; Leena Koulu; Ilkka Harvima; Kirsi Kalpala; Ying Wu; David Choy; John Michon; Nizar Smaoui; Fedik Rahimov; Anne Lehtonen; Dawn Waterworth; Justin Wade Davis; Bridget Riley-Gillis; Danjuma Quarless; Slavé Petrovski; Jimmy Liu; Chia-Yen Chen; Paola G. Bronson; Robert Yang; Joseph Maranville; Shameek Biswas; Diana Chang; Julie Hunkapiller; Tushar Bhangale; Natalie Bowers; Dorothée Diogo; Emily Holzinger; Padhraig Gormley; Xulong Wang; Xing Chen; Åsa Hedman; Kirsi Auro; Clarence Wang; Ethan Xu; Franck Auge; Clement Chatelain; Samuli Ripatti; Kimmo Palin; Pietro della Briotta Parolo; Wei Zhou; Manuel Rivas; Aarno Palotie; Andrea Ganna; Vincent Llorens; Antti Karlsson; Mikko Arvas; Kati Hyvärinen; Jarmo Ritari; Tiina Wahlfors; Miika Koskinen; Olli Carpen; Johannes Kettunen; Katri Pylkäs; Marita Kalaoja; Minna Karjalainen; Tuomo Mantere; Eeva Kangasniemi; Sami Heikkinen; Arto Mannermaa; Eija Laakkonen; Juha Kononen; Lila Kallio; Sirpa Soini; Jukka Partanen; Kimmo Pitkänen; Seppo Vainio; Kimmo Savinainen; Veli-Matti Kosma; Teijo Kuopio; Anu Jalanko; Risto Kajanne; Ulrike Lyhs; Mitja Kurki; Juha Karjalainen; Pietro della Briotta Parola; Sina Rüeger; Arto Lehisto; Wei Zhou; Masahiro Kanai; Hannele Laivuori; Tuomo T. J. Kiiskinen; Mari Kaunisto; Jarmo Harju; Elina Kilpeläinen; Georg Brein; Oluwaseun A. Dada; Ghazal Awaisa; Anastasia Shcherban; Timo P. Sipilä; Kati Donner; Anu Loukola; Päivi Laiho; Tuuli Sistonen; Essi Kaiharju; Markku Laukkanen; Elina Järvensivu; Sini Lähteenmäki; Lotta Männikkö; Regis Wong; Hannele Mattsson; Kati Kristiansson; Susanna Lemmelä; Tero Hiekkalinna; Manuel González Jiménez; Priit Palta; Kalle Pärn; Javier Nunez-Fontarnau; Tarja Laitinen; Harri Siirtola; Javier Gracia Tabuenca; Michelle Agee; Babak Alipanahi; Adam Auton; Robert K. Bell; Katarzyna Bryc; Sarah L. Elson; Pierre Fontanillas; Nicholas A. Furlotte; David Hinds; Karen E. Huber; Aaron Kleinman; Nadia K. Litterman; Jennifer C. McCreight; Matthew H. McIntyre; Joanna L. Mountain; Elizabeth S. Noblin; Carrie A.M. Northover; Steven Pitts; J. Fah Sathirapongsasuti; Olga V. Sazonova; Janie F. Shelton; Suyash Shringarpure; Tian; Joyce Y. Tung; Vladimir Vacic; Catherine H. Wilson; Aviv Regev; Aarno Palotie; Neale; John E. Dick; Pradeep Natarajan; Christopher J. O’Donnell; Mark J. Daly; Michael Milyavsky; Sekar Kathiresan; Vijay G. Sankaran
View on Scopus
Monomeric Targeted Protein Degraders
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Emily J. Hanan; Jun Liang; Xiaojing Wang; Robert A. Blake; Nicole Blaquiere; Steven T. Staben
View on Scopus
Fit-for-purpose synthesis of dual leucine zipper kinase (DLK) inhibitor GNE-834
Tetrahedron Letters, ISSN: 18733581 00404039
Jie Xu; Diane Carrera; Danial Beaudry; Michael Siu; Malcolm P. Huestis; Wendy Liu; Remy Angelaud; Francis Gosselin
View on Scopus
Dimerization Induced by C-Terminal 14-3-3 Binding Is Sufficient for BRAF Kinase Activation
Biochemistry, ISSN: 15204995 00062960
Nicholas P. D. Liau; Avinashnarayan Venkatanarayan; John Quinn; Wilson Phung; Shiva Malek; Sarah G. Hymowitz; Jawahar Sudhamsu
View on Scopus
Optimization of globomycin analogs as novel gram-negative antibiotics
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Keira Garland; Homer Pantua; Marie-Gabrielle Braun; Burdick; Georgette M. Castanedo; Yi-Chen Chen; Yun-Xing Cheng; Jonathan Cheong; Blake E. Daniels; Gauri Deshmukh; Yuhong Fu; Paul Gibbons; Susan L. Gloor; Rongbao Hua; Sharada Labadie; Xiongcai Liu; Richard Pastor; Craig E. Stivala; Min Xu; Yiming Xu; Hao Zheng; Sharookh B. Kapadia; Emily J. Hanan
View on Scopus
Exposure-safety and exposure-efficacy analyses of polatuzumab vedotin in patients with relapsed or refractory diffuse large B-cell lymphoma
Leukemia and Lymphoma, ISSN: 10292403 10428194
Tong Lu; Leonid Gibiansky; Xiaobin Li; Chunze Li; Rong Shi; Priya Agarwal; Jamie Hirata; Dale Miles; Pascal Chanu; Sandhya Girish; Jin Yan Jin; Dan Lu
View on Scopus
Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with early-stage triple-negative breast cancer (IMpassion031): a randomised, double-blind, phase 3 trial
The Lancet, ISSN: 1474547X 01406736
Elizabeth A Mittendorf; Hong Zhang; Carlos H. Barrios; Shigehira Saji; Kyung Hae Jung; Roberto Hegg; Andreas Koehler; Joo-Hyuk Sohn; Iwata; Melinda L Telli; Cristiano Ferrario; Kevin Punie; Frederique Penault-Llorca; Shilpen Patel; Anh Nguyen Duc; Liste Hermoso; Maiya; Luciana L. Molinero; Chui; Nadia Harbeck
View on Scopus
Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with early-stage triple-negative breast cancer (IMpassion031): a randomised, double-blind, phase 3 trial
The Lancet, ISSN: 1474547X 01406736
Elizabeth A Mittendorf; Hong Zhang; Carlos H. Barrios; Shigehira Saji; Kyung Hae Jung; Roberto Hegg; Andreas Koehler; Joo-Hyuk Sohn; Iwata; Melinda L Telli; Cristiano Ferrario; Kevin Punie; Frederique Penault-Llorca; Sharmi Patel; Anh Nguyen Duc; Liste Hermoso; Maiya; Luciana L. Molinero; Chui; Nadia Harbeck
View on Scopus
Discovery of A-1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL-XLInhibitor
ACS Medicinal Chemistry Letters, ISSN: 19485875
Le Wang; George A. Doherty; Andrew S. Judd; Zhi-Fu Tao; T. Matthew Hansen; Robin R. Frey; Xiaohong Song; Bruncko; Aaron R. Kunzer; Xilu Wang; Michael D. Wendt; Flygare; Nathaniel D. Catron; Russell A. Judge; Chang H. Park; Shashank Shekhar; Darren C. Phillips; Paul M. Nimmer; Morey L. Smith; Stephen K. Tahir; Yu Xiao; John Xue; Haichao Zhang; Phuong N. Le; Michael J. Mitten; Erwin R. Boghaert; Wenqing Gao; Peter J. Kovar; Edna F. Choo; Dolores Diaz; Wayne J. Fairbrother; Steven W. Elmore; Deepak Sampath; Joel D. Leverson; Andrew J. Souers
View on Scopus
Targeted Bottom-up Characterization of Recombinant Monoclonal Antibodies by Multidimensional LC/MS
Analytical Chemistry, ISSN: 15206882 00032700
Julien Camperi; Davy Guillarme; Cinzia Stella
View on Scopus
Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial
The Lancet Respiratory Medicine, ISSN: 22132619 22132600
Dinesh Khanna; Celia J.F. Lin; Daniel E. Furst; Goldin; Kim; Masataka Kuwana; Yannick Allanore; Marco Matucci-Cerinic; Oliver Distler; Shima; Helen Spotswood; Bridget Wagner; Jeffrey N. Siegel; Angelika Jahreis; Eleonora Lucero; Bernardo A. Pons-Estel; Mariano Rivero; Guillermo Tate; Vanessa Smith; Ellen De Langhe; Rasho Rashkov; Anastas Batalov; Ivan Goranov; Rumen Stoilov; James Dunne; Sindhu R. Johnson; Janet E. Pope; Dušanka Martinović Kaliterna; Mette Mogensen; Anne Braae Olesen; Joerg Christoph Henes; Ulf Müller-Ladner; Gabriela Riemekasten; Alla Skapenko; Panayiotis Vlachoyiannopoulos; Emese Kiss; Tünde Minier; Lorenzo Beretta; Elisa Gremese; Gabriele Valentini; Yoshihide Asano; Tatsuya Atsumi; Hironobu Ihn; Tomonori Ishii; Osamu Ishikawa; Hiroki Takahashi; Kazuhiko Takehara; Yoshiya Tanaka; Yoshioki Yamasaki; Loreta Bukauskiene; Irena Butrimiene; Gabriel Medrano Ramirez; Cesar Ramos-Remus; Tatiana Sofia Rodriguez Reyna; Jeska de Vries-Bouwstra; Jacob M. Van Laar; Bogdan Batko; Slawomir Jeka; Eugeniusz Kucharz; Maria Majdan; Marzena Olesinska; Zaneta Smolenska; Jose Alves; Maria Jose Santos; Carmen Marina Mihai; Simona Rednic; Ivan Castellvi Barranco; Francisco Javier Lopez Longo; Carmen Simeon Aznar; Patricia Carreira; Ulrich A. Walker; Emma Derrett-Smith; Bridget Griffiths; Neil McKay; Christopher P. Denton; Jacob Aelion; Michael Borofsky; Roy Fleischmann; Joseph Z. Forstot; Daniel E. Furst; Suzanne Kafaja; M. Faisal Khan; Michael Kohen; Richard W. Martin; Fabian Mendoza-Ballesteros; Alireza Nami; Shirley Pang; Grissel Rios; Robert W. Simms; Keith Michael Sullivan; Virginia D. Steen
View on Scopus
Physiologically Based Pharmacokinetic Model-Informed Drug Development for Polatuzumab Vedotin: Label for Drug-Drug Interactions Without Dedicated Clinical Trials
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Divya Samineni; Hao Ding; Fang Ma; Rong Shi; Dan Lu; Dale Miles; Jialin Mao; Chunze Li; Jin Jin; Matthew Wright; Sandhya Girish; Yuan Chen
View on Scopus
Impact of Physiologically Based Pharmacokinetics, Population Pharmacokinetics and Pharmacokinetics/Pharmacodynamics in the Development of Antibody-Drug Conjugates
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Chunze Li; Shang-Chiung Chen; Yuan Chen; Sandhya Girish; Matts Kaagedal; Dan Lu; Tong Lu; Divya Samineni; Jin Yan Jin
View on Scopus
Evaluation of two point of care technologies for measuring monoclonal antibody therapeutic-A concentrations in blood
Bioanalysis, ISSN: 17576199 17576180
Saloumeh Kadkhodayan Fischer; Kathi Williams; Ian Harmon; Bryan Bothwell; Hua Xu; Emmanuel Capio; Mikhail Briman
View on Scopus
Development of a specific immunoassay to selectively measure active tryptase in airway samples
Bioanalysis, ISSN: 17576199 17576180
Gizette Sperinde; Meire C. Bremer; Henry R. Maun; Amos Baruch; Lazarus; James T. Koerber; Rajesh Vij; Tangsheng Yi; Saloumeh Kadkhodayan Fischer; Tracy Staton
View on Scopus
Using prednisolone and cortisol assays to assess adherence in oral corticosteroid dependant asthma: An analysis of test-retest repeatability
Pulmonary Pharmacology and Therapeutics, ISSN: 15229629 10945539
John Busby; Cecile Holweg; Akiko Chai; Peter Bradding; Rekha Chaudhuri; Adel Mansur; Matthews; Andrew Menzies-Gow; James Lordan; Robert Niven; Liam G. Heaney
View on Scopus
Reply
Ophthalmology Retina, ISSN: 24686530
Yogin Patel; Daniel M. Miller; Anne E. Fung; Philip J. Rosenfeld
View on Scopus
Atezolizumab for first-line treatment of PD-L1–selected patients with NSCLC
New England Journal of Medicine, ISSN: 15334406 00284793
Roy S. Herbst; Giuseppe Giaccone; Filippo De Marinis; Niels Reinmuth; Alain Vergnenegre; Carlos H. Barrios; Masahiro Morise; Enriqueta Felip; Zoran Andric; Sarayut Geater; Mustafa Özgüroğlu; Wei Zou; Alan Sandler; Ida Enquist; Kimberly M. Komatsubara; Deng; Hiroshi Kuriki; Wen; Mark L. McCleland; Mocci; Jacek Jassem; David Spigel
View on Scopus
Single-cell transcriptome profiling of the kidney glomerulus identifies key cell types and reactions to injury
Journal of the American Society of Nephrology, ISSN: 15333450 10466673
Jun-Jae Chung; Leonard D. Goldstein; Ying-Jiun J. Chen; Jiyeon Lee; Webster; Merone Roose-Girma; Sharad C. Paudyal; Zora Modrusan; Anwesha Dey; Andrey S. Shaw
View on Scopus
Regional variations in adverse event reporting rates and ACR responses in placebo/standard-of-care arms of rheumatoid arthritis trials
Rheumatology, ISSN: 14620332 14620324
Daniel Keebler; Edmond Teng; Jenny Chia; Joshua Galanter; Jodie Peake; Katie Tuckwell
View on Scopus
Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial
The Lancet Respiratory Medicine, ISSN: 22132619 22132600
Dinesh Khanna; Celia J.F. Lin; Goldin; Kim; Masataka Kuwana; Yannick Allanore; Marco Matucci-Cerinic; Oliver Distler; Shima; Helen Spotswood; Bridget Wagner; Jeffrey N. Siegel; Angelika Jahreis; Eleonora Lucero; Bernardo A. Pons-Estel; Mariano Rivero; Guillermo Tate; Vanessa Smith; Ellen De Langhe; Rasho Rashkov; Anastas Batalov; Ivan Goranov; Rumen Stoilov; James Dunne; Sindhu R. Johnson; Janet E. Pope; Dušanka Martinović Kaliterna; Mette Mogensen; Anne Braae Olesen; Joerg Christoph Henes; Ulf Müller-Ladner; Gabriela Riemekasten; Alla Skapenko; Panayiotis Vlachoyiannopoulos; Emese Kiss; Tünde Minier; Lorenzo Beretta; Elisa Gremese; Gabriele Valentini; Yoshihide Asano; Tatsuya Atsumi; Hironobu Ihn; Tomonori Ishii; Osamu Ishikawa; Hiroki Takahashi; Kazuhiko Takehara; Yoshiya Tanaka; Yoshioki Yamasaki; Loreta Bukauskiene; Irena Butrimiene; Gabriel Medrano Ramirez; Cesar Ramos-Remus; Tatiana Sofia Rodriguez Reyna; Jeska de Vries-Bouwstra; Jacob M. Van Laar; Bogdan Batko; Slawomir Jeka; Eugeniusz Kucharz; Maria Majdan; Marzena Olesinska; Zaneta Smolenska; Jose Alves; Maria Jose Santos; Carmen Marina Mihai; Simona Rednic; Ivan Castellvi Barranco; Francisco Javier Lopez Longo; Carmen Simeon Aznar; Patricia Carreira; Ulrich A. Walker; Emma Derrett-Smith; Bridget Griffiths; Neil McKay; Christopher P. Denton; Jacob Aelion; Michael Borofsky; Roy Fleischmann; Joseph Z. Forstot; Daniel E. Furst; Suzanne Kafaja; M. Faisal Khan; Michael Kohen; Richard W. Martin; Fabian Mendoza-Ballesteros; Alireza Nami; Shirley Pang; Grissel Rios; Robert W. Simms; Keith Michael Sullivan; Virginia D. Steen
View on Scopus
Inter-individual and inter-regional variations in enteric drug metabolizing enzyme activities: Results with cryopreserved human intestinal mucosal epithelia (CHIM) from the small intestines of 14 donors
Pharmacology Research and Perspectives, ISSN: 20521707
Albert P. Li; Ming-Chih D Ho; Novera Alam; Walter Mitchell; Susan C. Wong; Zhengyin Yan; Jane R. Kenny; Cornelis E C A Hop
View on Scopus
Maintenance rituximab in Veterans with follicular lymphoma
Cancer Medicine, ISSN: 20457634
Ahmad S. Halwani; Kelli M. Rasmussen; Vikas Patil; Deborah Morreall; Catherine C. Li; Christina M. Yong; Zachary Burningham; Keith Dawson; Anthony Masaquel; Kevin Henderson; Elisha DeLong-Sieg; Brian C. Sauer
View on Scopus
Ranibizumab in Diabetic Retinopathy with or without Diabetic Macular Edema
Ophthalmology Retina, ISSN: 24686530
Andrew N. Antoszyk; Kathleen Wade Tarnowski; Karen Basu; Jason S. Ehrlich; Zdenka Haskova
View on Scopus
Outcomes in children with hemophilia A with inhibitors: Results from a noninterventional study
Pediatric Blood and Cancer, ISSN: 15455017 15455009
Johannes Oldenburg; Midori Shima; Kruse-Jarres; Elena Santagostino; Johnny N. Mahlangu; Michaela Lehle; Nives Selak Bienz; Sammy Chebon; Elina Asikanius; Peter C. Trask; Mancuso; Jiménez-Yuste; Sylvia von Mackensen; Gallia Levy
View on Scopus
Evaluation of Super Refined™ Polysorbate 20 With Respect to Polysorbate Degradation, Particle Formation and Protein Stability
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Nidhi Doshi; Raphael Fish; Karina Padilla; Sandeep Yadav
View on Scopus
Strategy for Determining the Free Fraction of Labile Covalent Modulators in Plasma Using Equilibrium Dialysis
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Christian Leung; Jane R. Kenny; Cornelis E. Hop; Zhengyin Yan
View on Scopus
A Phase Ib Study to Evaluate the MEK Inhibitor Cobimetinib in Combination with the ERK1/2 Inhibitor GDC-0994 in Patients with Advanced Solid Tumors
Oncologist, ISSN: 1549490X 10837159
Colin D. Weekes; Albert Craig Lockhart; Patricia M. LoRusso; Elaine R. Murray; Erica Park; Tagen; Jatinder Singh; Indrani Sarkar; Lars Mueller; Hatem Dokainish; Geoffrey I. Shapiro; Howard A. Burris
View on Scopus
Spectral-Domain OCT Analysis of Risk Factors for Macular Atrophy Development in the HARBOR Study for Neovascular Age-Related Macular Degeneration
Ophthalmology, ISSN: 15494713 01616420
Srinivas Sadda; Nizar Saleh Abdelfattah; Jianqin Lei; Yue Shi; Kenneth M. Marion; Elizabeth A. Morgenthien; Shamika Gune; Siva Balasubramanian
View on Scopus
Phase 1 study of epacadostat in combination with atezolizumab for patients with previously treated advanced nonsmall cell lung cancer
International Journal of Cancer, ISSN: 10970215 00207136
Matthew D. Hellmann; Scott Gettinger; Laura Q.M. Chow; Michael S. Gordon; Mark M. Awad; Edward Cha; Xiaohua Gong; Gongfu Zhou; Chris Walker; Lance Leopold; Rebecca S. Heist
View on Scopus
Using prednisolone and cortisol assays to assess adherence in oral corticosteroid dependant asthma: An analysis of test-retest repeatability
Pulmonary Pharmacology and Therapeutics, ISSN: 15229629 10945539
John Busby; Cecile Holweg; Akiko Chai; Peter Bradding; Rekha Chaudhuri; Adel Mansur; John Matthews; Andrew Menzies-Gow; James Lordan; Robert Niven; Liam G. Heaney
View on Scopus
Paenibacillus infection with frequent viral coinfection contributes to postinfectious hydrocephalus in Ugandan infants
Science Translational Medicine, ISSN: 19466242 19466234
Joseph N. Paulson; Brent L. Williams; Christine Hehnly; Nischay Mishra; Shamim A. Sinnar; Lijun Zhang; Paddy Ssentongo; Edith Mbabazi-Kabachelor; Dona S.S. Wijetunge; Benjamin von Bredow; Ronnie Mulondo; Julius Kiwanuka; Francis Bajunirwe; Joel Bazira; Lisa M. Bebell; Kathy Burgoine; Mara Couto-Rodriguez; Jessica E. Ericson; Tim Erickson; Matthew Ferrari; Melissa Gladstone; Cheng Guo; Murali Haran; Mady Hornig; Albert M. Isaacs; Brian Nsubuga Kaaya; Sheila M. Kangere; Abhaya V. Kulkarni; Elias Kumbakumba; Xiaoxiao Li; David D. Limbrick; Joshua Magombe; Sarah U. Morton; John Mugamba; James Ng; Peter Olupot-Olupot; Justin Onen; Mallory R. Peterson; Farrah Roy; Kathryn Sheldon; Townsend; Andrew D. Weeks; Andrew J. Whalen; John Quackenbush; Peter Ssenyonga; Michael Y. Galperin; Mathieu Almeida; Hannah Atkins; Benjamin C. Warf; W. Ian Lipkin; James R. Broach; Steven J. Schiff
View on Scopus
Practical Synthesis of a Stable Precursor for Positron Emission Tomography Imaging Agent 18F-GTP1
Organic Process Research and Development, ISSN: 1520586X 10836160
Nicholas A. White; Kyle Clagg; Lauren E. Sirois; Ngiap-Kie Lim; William A. Nack; Paul D. O'Shea; Haiming Zhang; Francis Gosselin
View on Scopus
Conjugation Site Influences Antibody-Conjugated Drug PK Assays: Case Studies for Disulfide-Linked, Self-Immolating Next-Generation Antibody Drug Conjugates
Analytical Chemistry, ISSN: 15206882 00032700
M. Violet Lee; Surinder Kaur; Ola M. Saad
View on Scopus
Systematic Variation of Pyrrolobenzodiazepine (PBD)-Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody-Drug Conjugates
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Leanna Staben; Jinhua Chen; Josefa Dela Cruz-Chuh; Geoffrey Del Rosario; MaryAnn Go; Jun Guo; S. Cyrus Khojasteh; Katherine R. Kozak; Guangmin Li; Carl Ng; Gail D. Lewis Phillips; Thomas H. Pillow; Rebecca K. Rowntree; John Wai; Binqing Wei; Keyang Xu; Zijin Xu; Shang-Fan Yu; Donglu Zhang; Peter Dragovich
View on Scopus
Development of a rapid reversed-phase liquid chromatographic method for total free thiol quantitation in protein therapeutics
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Bingchuan Wei; Weitao Jia; Yi Yang; Mansour Jazayri; David Fulchiron; Justin Jeong; Qian Cai; Charlene Li; Briggs; Milady Ninonuevo; Hongbin Liu; Zane Liu; Yonghua Taylor Zhang
View on Scopus
Ectoine and Hydroxyectoine Stabilize Antibodies in Spray-Dried Formulations at Elevated Temperature and during a Freeze/Thaw Process
Molecular Pharmaceutics, ISSN: 15438392 15438384
Purnendu K. Nayak; Meghan Goode; Debby P. Chang; Karthikan Rajagopal
View on Scopus
Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia
Cell, ISSN: 10974172 00928674
Ada Ndoja; Rohit Reja; Seung-Hye Lee; Webster; Hai Ngu; Christopher M. Rose; Donald S. Kirkpatrick; Zora Modrusan; Ying-Jiun J. Chen; Dugger; Vineela D. Gandham; Luke Xie; Kim Newton; Vishva M. Dixit
View on Scopus
Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry
Journal of the American Society for Mass Spectrometry, ISSN: 18791123
Kristina Srzentić; Luca Fornelli; Yury O. Tsybin; Joseph A Loo; Henrique Seckler; Jeffrey N Agar; Lissa C. Anderson; Dina L. Bai; Alain Beck; Jennifer S. Brodbelt; Yuri E M van der Burgt; Julia Chamot-Rooke; Sneha Chatterjee; Yunqiu Chen; David J. Clarke; Paul O. Danis; Jolene K. Diedrich; Robert A. D'Ippolito; Mathieu Dupré; Natalia Gasilova; Ying Ge; Young Ah Goo; David R. Goodlett; Sylvester Greer; Kim F. Haselmann; Lidong He; Christopher L. Hendrickson; Joshua D. Hinkle; Matthew V. Holt; Sam Hughes; Donald F. Hunt; Neil L Kelleher; Anton N. Kozhinov; Ziqing Lin; Christian Malosse; Alan G. Marshall; Laure Menin; Robert J. Millikin; Konstantin O. Nagornov; Simone Nicolardi; Ljiljana Paša-Tolić; Stuart Pengelley; Neil R. Quebbemann; Anja Resemann; Wendy N. Sandoval; Richa Sarin; Nicholas D. Schmitt; Jeffrey Shabanowitz; Jared B. Shaw; Michael R. Shortreed; Lloyd M Smith; Frank Sobott; Detlev Suckau; Timothy Toby; Chad R. Weisbrod; Norelle C. Wildburger; John R. Yates; Sung Hwan Yoon; Nicolas L Young; Mowei Zhou
View on Scopus
Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry
Journal of the American Society for Mass Spectrometry, ISSN: 18791123 10440305
Kristina Srzentić; Luca Fornelli; Yury O. Tsybin; Joseph A Loo; Henrique Seckler; Jeffrey N Agar; Lissa C. Anderson; Dina L. Bai; Alain Beck; Jennifer S. Brodbelt; Yuri E M van der Burgt; Julia Chamot-Rooke; Sneha Chatterjee; Yunqiu Chen; David J. Clarke; Paul O. Danis; Jolene K. Diedrich; Robert A. D'Ippolito; Mathieu Dupré; Natalia Gasilova; Ying Ge; Young Ah Goo; David R. Goodlett; Sylvester Greer; Kim F. Haselmann; Lidong He; Christopher L. Hendrickson; Joshua D. Hinkle; Matthew V. Holt; Sam Hughes; Donald F. Hunt; Neil L Kelleher; Anton N. Kozhinov; Ziqing Lin; Christian Malosse; Alan G. Marshall; Laure Menin; Robert J. Millikin; Konstantin O. Nagornov; Simone Nicolardi; Ljiljana Paša-Tolić; Stuart Pengelley; Neil R. Quebbemann; Anja Resemann; Wendy N. Sandoval; Richa Sarin; Nicholas D. Schmitt; Jeffrey Shabanowitz; Jared B. Shaw; Michael R. Shortreed; Lloyd M Smith; Frank Sobott; Detlev Suckau; Timothy Toby; Chad R. Weisbrod; Norelle C. Wildburger; John R. Yates; Sung Hwan Yoon; Nicolas L Young; Mowei Zhou
View on Scopus
What works and what does not work in Alzheimer’s disease? From interventions on risk factors to anti-amyloid trials
Journal of Neurochemistry, ISSN: 14714159 00223042
Szofia Bullain; Rachelle S. Doody
View on Scopus
Model of short- And long-term outcomes of emicizumab prophylaxis treatment for persons with Hemophilia A
Journal of Managed Care and Specialty Pharmacy, ISSN: 23761032 23760540
Zheng-Yi Zhou; Karina Raimundo; Anisha M. Patel; Simeng Han; Yusi Ji; Honghao Fang; Jia Zhong; Betts; Arash Mahajerin
View on Scopus
Effects of Mu-Opiate Receptor Gene Polymorphism rs1799971 (A118G) on the Antidepressant and Dissociation Responses in Esketamine Nasal Spray Clinical Trials
International Journal of Neuropsychopharmacology, ISSN: 14695111 14611457
Ziad Saad; Derrek P. Hibar; Maggie Fedgchin; Vanina Popova; Maura L. Furey; Jaskaran B. Singh; Hartmuth Kolb; Wayne C. Drevets; Guang Chen
View on Scopus
Compendial Methods: Suitability Verification, Challenges and Recommendations for Proteins
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124
Wen-Li Chung; Jian Yin; Steven Messick; Miguel Saggu; Kate Tschudi; Ann Marie Woys; Rod Rahimi; Marianne Azarias; Connie Kong; Bruce Kabakoff
View on Scopus
Fast, Robust, and Sensitive Identification of Residual Host Cell Proteins in Recombinant Monoclonal Antibodies Using Sodium Deoxycholate Assisted Digestion
Analytical Chemistry, ISSN: 15206882 00032700
Delia Li; Adam Farchone; Qing Zhu; Frank D. Macchi; Donald Walker; David A. Michels; Feng Yang
View on Scopus
Quantitative mapping of transcriptome and proteome dynamics during polarization of human ipsc-derived neurons
eLife, ISSN: 2050084X
Feline W Lindhout; Robbelien Kooistra; Sybren Portegies; Lotte J. Herstel; Riccardo Stucchi; Basten L. Snoek; Maarten Altelaar; Harold MacGillavry; Corette J. Wierenga; Casper C Hoogenraad
View on Scopus
© 2024 Genentech, Inc. All rights reserved. This site is intended for US residents only.