Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 2701 - 2750 OF 15572 RESULTS

Targeting Autophagy to Treat Cancer: Challenges and Opportunities
Frontiers in Pharmacology, ISSN: 16639812
Junghyun Lim; Aditya Murthy
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Green chemistry articles of interest to the pharmaceutical industry
Organic Process Research and Development, ISSN: 1520586X 10836160
Alba Diaz Rodriguez; Charlotte Dalton; Louis Diorazio; Jaika Doerfler; Oliver D. Engl; Matthew Hickey; Gareth Howell; Marc Hutchby; Jonathan Latham; Wei Li; Rachel Munday; Paul Richardson; Philipp C. Roosen; Alan Steven; Jack A. Terrett; Daniel S. Treitler; Timothy White; Mingshuo Zeng
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Achiral-Chiral Two-Dimensional Liquid Chromatography Platform to Support Automated High-Throughput Experimentation in the Field of Drug Development
Analytical Chemistry, ISSN: 15206882 00032700
Alexandre Goyon; Colin Masui; Lauren E. Sirois; Chong Han; Peter M. Yehl; Francis Gosselin; Kelly Zhang
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Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis
Cell Reports Medicine, ISSN: 26663791
Xia Gao; Guiquan Jia; Anna Guttman; Daryle J. DePianto; Katrina B. Morshead; Kai-Hui Sun; Nandhini Ramamoorthi; Jason A. Vander Heiden; Zora Modrusan; Paul J. Wolters; Angelika Jahreis; Joseph R. Arron; Dinesh Khanna; Thirumalai R. Ramalingam
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Antibody-mediated activation of the FGFR1/Klothoβ complex corrects metabolic dysfunction and alters food preference in obese humans
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Amos Baruch; Chin Wong; Leslie Chinn; Vaze; Junichiro Sonoda; Thomas R. Gelzleichter; Shan Chen; Nicholas Lewin-Koh; Linda Morrow; Suresh Dheerendra; Richard Boismenu; Johnny Gutierrez; Eric Wakshull; Maria E. Wilson; Puneet S. Arora
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Practical Early Development Synthesis of Nav17 Inhibitor GDC-0310
Synthesis (Germany), ISSN: 1437210X 00397881
Andreas Stumpf; Frederic St-Jean; David Lao; Zhigang Cheng; Remy Angelaud; Francis Gosselin
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Synthesis of an Azabicyclo[31.0]hexanone-Containing Inhibitor of NF-κΒ Inducing Kinase via Catalytic C-H Activation
Synthesis (Germany), ISSN: 1437210X 00397881
James J. Crawford; Daohong Liao; Aleksandr Kolesnikov; Wendy Lee; Matthew L. Landry
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Generalized additive mixed modeling of longitudinal tumor growth reduces bias and improves decision making in translational oncology
Cancer Research, ISSN: 15387445 00085472
William F. Forrest; Bruno Alicke; Oleg Mayba; Magdalena Osinska; Michal Jakubczak; Pawel Piatkowski; Lech Choniawko; Alice Starr; Stephen Gould
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Using differential scanning calorimetry for the development of non-reduced capillary electrophoresis sodium dodecyl sulfate methods for monoclonal antibodies
Analytical Biochemistry, ISSN: 10960309 00032697
Patricia Molina; Arthur J. Schick; Leslie Welch; Thomas Niedringhaus; Gabriella del Hierro; Galahad Deperalta; Aaron R. Hieb
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Visible-Light Photocatalysis as an Enabling Technology for Drug Discovery: A Paradigm Shift for Chemical Reactivity
ACS Medicinal Chemistry Letters, ISSN: 19485875
Peijun Li; Jack A. Terrett; Jason R. Zbieg
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Integration of innate immune signalling by caspase-8 cleavage of N4BP1
Nature, ISSN: 14764687 00280836
Alexander D. Gitlin; Klaus D. Heger; Alexander F Schubert; Rohit Reja; Donghong Yan; Victoria Pham; Eric Suto; Juan Zhang; Youngsu C. Kwon; Emily C. Freund; Jing Kang; Anna Pham; Roger Caothien; Natasha Bacarro; Trent Hinkle; Min Xu; Brent Mckenzie; Benjamin Haley; Wyne P. Lee; Jennie R. Lill; Merone Roose-Girma; Monika Dohse; Webster; Kim Newton; Vishva M. Dixit
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Structure of the human sodium leak channel NALCN
Nature, ISSN: 14764687 00280836
Marc Kschonsak; Han Chow Chua; Cameron Noland; Claudia Weidling; Thomas Clairfeuille; Oskar Ørts Bahlke; Aishat Oluwanifemi Ameen; Zhong Rong Li; Christopher P. Arthur; Claudio Ciferri; Stephan Alexander Pless; Jian Payandeh
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Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers
Journal of Experimental Medicine, ISSN: 15409538 00221007
Allyson L. Byrd; Menghan Liu; Fujimura; Svetlana Lyalina; Deepti R. Nagarkar; Bruno Charbit; Jacob Bergstedt; Etienne Patin; Oliver J. Harrison; Lluis Quintana-Murci; Ira Mellman; Darragh Duffy; Matthew L. Albert
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Augmenting Anticancer Immunity Through Combined Targeting of Angiogenic and PD-1/PD-L1 Pathways: Challenges and Opportunities
Frontiers in Immunology, ISSN: 16643224
Stephen P. Hack; Zhu; Wang
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Augmenting Anticancer Immunity Through Combined Targeting of Angiogenic and PD-1/PD-L1 Pathways: Challenges and Opportunities
Frontiers in Immunology, ISSN: 16643224
Stephen P. Hack; Andrew X. Zhu; Wang
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Zero-Valent Iron Sand Filtration Can Reduce Human and Plant Pathogenic Bacteria While Increasing Plant Growth Promoting Bacteria in Reclaimed Water
Frontiers in Environmental Science, ISSN: 2296665X
Prachi Kulkarni; Nathan D. Olson; Anthony Q. Bui; Rhodel N. Bradshaw; Laura P. Del Collo; Lauren E. Hittle; Eric T. Handy; Joseph N. Paulson; Jay Ghurye; Daniel J. Nasko; Cheryl East; Jo Ann Van Kessel; Kalmia E. Kniel; Pei C. Chiu; Emmanuel F. Mongodin; Mihai Pop; Manan Sharma; Amy R. Sapkota
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Improving Prediction of Free Fatty Acid Particle Formation in Biopharmaceutical Drug Products: Incorporating Ester Distribution during Polysorbate 20 Degradation
Molecular Pharmaceutics, ISSN: 15438392 15438384
Nidhi Doshi; Joelle Martin; Anthony Tomlinson
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Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human
Molecular Pharmaceutics, ISSN: 15438392 15438384
Abdul Basit; Naveen K. Neradugomma; Chris Wolford; Peter W. Fan; Bernard P. Murray; Ryan Takahashi; S. Cyrus Khojasteh; Bill J. Smith; Scott Heyward; Rheem A. Totah; Edward J. Kelly; Bhagwat Prasad
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MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence
Neuro-Oncology, ISSN: 15235866 15228517
Radhika Mathur; Yalan Zhang; Matthew R. Grimmer; Chibo Hong; Michael Zhang; Saumya Bollam; Kevin Petrecca; Jennifer Clarke; Mitchel S. Berger; Joanna J. Phillips; Nancy Ann Oberheim-Bush; Annette M. Molinaro; Susan Chang; Joseph F. Costello
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Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation
PLoS ONE, ISSN: 19326203
Nalle; Rosa Barreira da Silva; Hua Zhang; Markus Decker; Cecile Chalouni; Min Xu; George Posthuma; Ann De Mazière; Judith Klumperman; Adriana Baz Morelli; Sebastian J. Fleire; Alan S. Verkman; E. Sergio Trombetta; Matthew L. Albert; Ira Mellman
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Comparison of techniques to control ice nucleation during lyophilization
Processes, ISSN: 22279717
Jacob Luoma; Erika Ingham; Carmen Lema Martinez; Andrea Allmendinger
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Characterization of tissue distribution, catabolism, and elimination of an anti-staphylococcus aureus thiomab antibody-antibiotic conjugate in rats
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Hao Cai; Victor Yip; M. Violet Lee; Sylvia Wong; Ola M. Saad; Shuguang Ma; Nina Ljumanovic; S. Cyrus Khojasteh; Amrita Kamath; Shen
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Health-related quality of life and caregiver burden of emicizumab in children with haemophilia A and factor VIII inhibitors—Results from the HAVEN 2 study
Haemophilia, ISSN: 13652516 13518216
Mancuso; Johnny N. Mahlangu; Robert F. Sidonio; Peter C. Trask; Marianne Uguen; Tiffany Chang; Midori Shima; Guy Young; Johannes Oldenburg; Sylvia von Mackensen
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Determining meaningful health-related quality-of-life improvement in persons with haemophilia A using the Haemophilia Quality of Life Questionnaire for Adults (Haem-A-QoL)
Haemophilia, ISSN: 13652516 13518216
Sylvia von Mackensen; Olivier Catalani; Elina Asikanius; Paz-Priel; Michaela Lehle; Peter C. Trask
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Response to: 'Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients' by Buch et al
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Frances Humby; Myles J. Lewis; Michael J. Townsend; Costantino Pitzalis
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Building on the success of anti-vascular endothelial growth factor therapy: a vision for the next decade
Eye, ISSN: 14765454 0950222X
Anthony P. Adamis; Christopher Brittain; Atul Dandekar; J. Jill Hopkins
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Water related impact of energy: Cost and carbon footprint analysis of water for biopharmaceuticals from tap to waste
Chemical Engineering Science: X, ISSN: 25901400
Alessandro Luigi Cataldo; Bernhard Sissolak; Karl Metzger; Kristi L. Budzinski; Osamu Shirokizawa; Markus Luchner; Alois Jungbauer; Peter Satzer
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Safety results of administering ocrelizumab per a shorter infusion protocol in patients with primary progressive and relapsing multiple sclerosis
Multiple Sclerosis and Related Disorders, ISSN: 22110356 22110348
Timothy Vollmer; Jeffrey A Cohen; Enrique Alvarez; Kavita V. Nair; Aaron Boster; Joshua Katz; Gabriel Pardo; Jinglan Pei; Pranil Raut; Sharmin Merchant; Elizabeth MacLean; Ashish Pradhan; Brandon Moss
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Impact of Silicone Oil on Free Fatty Acid Particle Formation due to Polysorbate 20 Degradation
Pharmaceutical Research, ISSN: 1573904X 07248741
Raphael Fish; Jasper C. Lin; Nidhi Doshi
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Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective
AAPS Journal, ISSN: 15507416
Arian Emami Riedmaier; Kevin Dement; James Huckle; Phil Bransford; Cordula Stillhart; Richard Lloyd; Ravindra Alluri; Sumit Basu; Yuan Chen; Varsha Dhamankar; Stephanie Dodd; Priyanka Kulkarni; Andrés Olivares-Morales; Chi-Chi Peng; Xavier Pepin; Xiaojun Ren; Thuy Tran; Christophe Tistaert; Tycho Heimbach; Filippos Kesisoglou; Christian Wagner; Neil Parrott
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Increased Bacillus Calmette-Guérin Treatment Intensity Associated With Improved Outcomes in Elderly Patients With Non–Muscle-invasive Bladder Cancer in United States Clinical Practice
Urology, ISSN: 15279995 00904295
Kyle A. Richards; Shih Wen Lin; Ching-Yi Chuo; Christina L. Derleth; Jingbo Yi; Marko Zivkovic; Sarika Ogale; Sandip Prasad; G. Joel Decastro; Gary D. Steinberg
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Evaluation of the Content Validity and Cross-Cultural Validity of the Study Participant Feedback Questionnaire (SPFQ)
Therapeutic Innovation and Regulatory Science, ISSN: 21684804 21684790
Alison Greene; Mary Elmer; Sean Ludlam; Kathyjo Shay; Sarah Bentley; Claire Trennery; Rebecca Grimes; Adam Gater
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Agreement of Spectral-Domain OCT with Fluorescein Leakage in Neovascular Age-Related Macular Degeneration: Post Hoc Analysis of the HARBOR Study
Ophthalmology Retina, ISSN: 24686530
Rahul N. Khurana; Lauren Hill; Avanti Ghanekar; Shamika Gune
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MDM2 inhibition: an important step forward in cancer therapy
Leukemia, ISSN: 14765551 08876924
Marina Konopleva; Giovanni Martinelli; Naval Daver; Cristina Papayannidis; Andrew H. Wei; Higgins; Ott; John Mascarenhas; Michael Andreeff
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Pharmacokinetics of the Monoclonal Antibody MHAA4549A Administered in Combination With Oseltamivir in Patients Hospitalized With Severe Influenza A Infection
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Rong Deng; Gaohong She; Mauricio Maia; Jeremy Lim; Melicent Peck; Jacqueline McBride; Priya Kulkarni; Priscilla Horn; Aide Castro; Elizabeth Newton; Jorge A. Tavel; William D. Hanley
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Response to “Externally Controlled Trials: Are We There Yet?”
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Gillis Carrigan; Samuel Whipple; William B. Capra; Michael D. Taylor; Jeffrey S. Brown; Michael W. Lu; Brandon Arnieri; Ryan Copping; Kenneth J. Rothman
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Modulation of Notch1 signaling regulates bone fracture healing
Journal of Orthopaedic Research, ISSN: 1554527X 07360266
Sanja Novak; Emilie Roeder; Benjamin P. Sinder; Douglas J. Adams; Christian W. Siebel; Danka Grcevic; Kurt D. Hankenson; Brya G. Matthews; Ivo Kalajzic
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Autoimmunity linked protein phosphatase PTPN22 as a target for cancer immunotherapy
Journal for ImmunoTherapy of Cancer, ISSN: 20511426
Rafael Cubas; Zia Khan; Qian Gong; Marina Moskalenko; Huizhong Xiong; Qinglin Ou; Christine Pai; Ryan Rodriguez; Jeanne Cheung; Andrew A. Chan
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A phase I study of pharmacokinetics of trastuzumab emtansine in Chinese patients with locally advanced inoperable or metastatic human epidermal growth factor receptor 2-positive breast cancer who have received prior trastuzumab-based therapy
Medicine (United States), ISSN: 15365964
Dongmei Ji; Weina Shen; Jian Zhang; Junning Cao; Wenhua Li; Lisa H. Lam; Fan Wu; Wang; Zao Li; Guofang Sun; Xichun Hu; Shang-Chiung Chen
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Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
Nature, ISSN: 14764687 00280836
Erik L. Bao; Satish K. Nandakumar; Xiaotian Liao; Alexander G. Bick; Marcin Tabaka; Olga I. Gan; Aki S. Havulinna; Caleb A. Lareau; Aitzkoa L. de Lapuente Portilla; Bo Li; Connor Emdin; Veryan Codd; Christopher P. Nelson; Christopher J. Walker; Claire Churchhouse; Albert de la Chapelle; Daryl E. Klein; Björn Nilsson; Peter W. F. Wilson; Kelly Cho; Saiju Pyarajan; J. Michael Gaziano; Nilesh J. Samani; Howard Jacob; Sally John; Robert M. Plenge; Mark I. McCarthy; Caroline Fox; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Jukka Partanen; Anne Pitkäranta; Riitta Kaarteenaho; Urho Kujala; Jimmy Liu; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Call; Kathy Klinger; Matthias Gossel; Johanna Schleutker; Markus Perola; Mikko Arvas; Reetta Hinttala; Reijo Laaksonen; Arto Mannermaa; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Sahar Esmaeeli; Susan Eaton; Sanni Lahdenperä; Janet van Adelsberg; Geoffrey A. Kerchner; Edmond Teng; John Eicher; Padhraig Gormley; Kari Linden; Christopher D. Whelan; Fanli Xu; David Pulford; Martti Färkkilä; Sampsa Pikkarainen; Airi Jussila; Timo Blomster; Mikko Kiviniemi; Markku Voutilainen; Graham Heap; Keith Usiskin; Tim Lu; Danny Oh; Xinli Hu; Linda McCarthy; Kari Eklund; Antti Palomäki; Pia Isomäki; Laura Pirilä; Oili Kaipiainen-Seppänen; Johanna Huhtakangas; Bob Georgantas; Apinya Lertratanakul; Marla Hochfeld; Nan Bing; Xinli Hu; Jorge Esparza Gordillo; Nina Mars; Margit Pelkonen; Paula Kauppi; Hannu Kankaanranta; Terttu Harju; David Close; Steven Greenberg; Hubert Chen; Jo Betts; Soumitra Ghosh; Veikko Salomaa; Teemu Niiranen; Markus Juonala; Kaj Metsärinne; Mika Kähönen; Juhani Junttila; Markku Laakso; Jussi Pihlajamäki; Juha Sinisalo; Marja-Riitta Taskinen; Tiinamaija Tuomi; Jari Laukkanen; Ben Challis; Andrew S. Peterson; Audrey Y. Chu; Jaakko Parkkinen; Melissa Miller; Anthony Muslin; Heikki Joensuu; Tuomo Meretoja; Lauri Aaltonen; Annika Auranen; Peeter Karihtala; Saila Kauppila; Päivi Auvinen; Elenius; Relja Popovic; Jeff Waring; Athena Matakidou; Jennifer L. Schutzman; Andrey Loboda; Aparna Chhibber; Heli Lehtonen; Stefan McDonough; Marika Crohns; Diptee Kulkarni; Kai Kaarniranta; Joni A. Turunen; Terhi Ollila; Sanna Seitsonen; Hannu Uusitalo; Vesa Aaltonen; Hannele Uusitalo-Järvinen; Marja Luodonpää; Nina Hautala; Heiko Runz; Erich C. Strauss; Hao Chen; Anna Podgornaia; Vinay Mehta; Joshua Hoffman; Kaisa Tasanen; Laura Huilaja; Katariina Hannula-Jouppi; Teea Salmi; Sirkku Peltonen; Leena Koulu; Ilkka Harvima; Kirsi Kalpala; Ying Wu; David Choy; John Michon; Nizar Smaoui; Fedik Rahimov; Anne Lehtonen; Dawn Waterworth; Justin Wade Davis; Bridget Riley-Gillis; Danjuma Quarless; Slavé Petrovski; Jimmy Liu; Chia-Yen Chen; Paola G. Bronson; Robert Yang; Joseph Maranville; Shameek Biswas; Diana Chang; Julie Hunkapiller; Tushar Bhangale; Natalie Bowers; Dorothée Diogo; Emily Holzinger; Padhraig Gormley; Xulong Wang; Xing Chen; Åsa Hedman; Kirsi Auro; Clarence Wang; Ethan Xu; Franck Auge; Clement Chatelain; Samuli Ripatti; Kimmo Palin; Pietro della Briotta Parolo; Wei Zhou; Manuel Rivas; Aarno Palotie; Andrea Ganna; Vincent Llorens; Antti Karlsson; Mikko Arvas; Kati Hyvärinen; Jarmo Ritari; Tiina Wahlfors; Miika Koskinen; Olli Carpen; Johannes Kettunen; Katri Pylkäs; Marita Kalaoja; Minna Karjalainen; Tuomo Mantere; Eeva Kangasniemi; Sami Heikkinen; Arto Mannermaa; Eija Laakkonen; Juha Kononen; Lila Kallio; Sirpa Soini; Jukka Partanen; Kimmo Pitkänen; Seppo Vainio; Kimmo Savinainen; Veli-Matti Kosma; Teijo Kuopio; Anu Jalanko; Risto Kajanne; Ulrike Lyhs; Mitja Kurki; Juha Karjalainen; Pietro della Briotta Parola; Sina Rüeger; Arto Lehisto; Wei Zhou; Masahiro Kanai; Hannele Laivuori; Tuomo T. J. Kiiskinen; Mari Kaunisto; Jarmo Harju; Elina Kilpeläinen; Georg Brein; Oluwaseun A. Dada; Ghazal Awaisa; Anastasia Shcherban; Timo P. Sipilä; Kati Donner; Anu Loukola; Päivi Laiho; Tuuli Sistonen; Essi Kaiharju; Markku Laukkanen; Elina Järvensivu; Sini Lähteenmäki; Lotta Männikkö; Regis Wong; Hannele Mattsson; Kati Kristiansson; Susanna Lemmelä; Tero Hiekkalinna; Manuel González Jiménez; Priit Palta; Kalle Pärn; Javier Nunez-Fontarnau; Tarja Laitinen; Harri Siirtola; Javier Gracia Tabuenca; Michelle Agee; Babak Alipanahi; Adam Auton; Robert K. Bell; Katarzyna Bryc; Sarah L. Elson; Pierre Fontanillas; Nicholas A. Furlotte; David Hinds; Karen E. Huber; Aaron Kleinman; Nadia K. Litterman; Jennifer C. McCreight; Matthew H. McIntyre; Joanna L. Mountain; Elizabeth S. Noblin; Carrie A.M. Northover; Steven Pitts; J. Fah Sathirapongsasuti; Olga V. Sazonova; Janie F. Shelton; Suyash Shringarpure; Tian; Joyce Y. Tung; Vladimir Vacic; Catherine H. Wilson; Aviv Regev; Aarno Palotie; Neale; John E. Dick; Pradeep Natarajan; Christopher J. O’Donnell; Mark J. Daly; Michael Milyavsky; Sekar Kathiresan; Vijay G. Sankaran
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Analysis of Spatial Organization of Suppressive Myeloid Cells and Effector T Cells in Colorectal Cancer—A Potential Tool for Discovering Prognostic Biomarkers in Clinical Research
Frontiers in Immunology, ISSN: 16643224
Natalie Zwing; Henrik Failmezger; Chia-Huey Ooi; Derrek P. Hibar; Marta Cañamero; Bruno Gomes; Fabien Gaire; Konstanty Korski
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Toward a Better Understanding of Bioassays for the Development of Biopharmaceuticals by Exploring the Structure-Antibody-Dependent Cellular Cytotoxicity Relationship in Human Primary Cells
Frontiers in Immunology, ISSN: 16643224
Sébastien Wieckowski; Cécile Avenal; Arturo V. Orjalo; Daniel Gygax; Florian Cymer
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Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
Nature, ISSN: 14764687 00280836
Erik L. Bao; Satish K. Nandakumar; Xiaotian Liao; Alexander G. Bick; Marcin Tabaka; Olga I. Gan; Aki S. Havulinna; Caleb A. Lareau; Aitzkoa L. de Lapuente Portilla; Bo Li; Connor Emdin; Veryan Codd; Christopher P. Nelson; Christopher J. Walker; Claire Churchhouse; Albert de la Chapelle; Daryl E. Klein; Björn Nilsson; Peter W. F. Wilson; Kelly Cho; Saiju Pyarajan; J. Michael Gaziano; Nilesh J. Samani; Mark Daly; Howard Jacob; Sally John; Robert M. Plenge; Mark I. McCarthy; Caroline Fox; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Jukka Partanen; Anne Pitkäranta; Riitta Kaarteenaho; Urho Kujala; Jimmy Liu; Shameek Biswas; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Call; Kathy Klinger; Matthias Gossel; Johanna Schleutker; Markus Perola; Mikko Arvas; Reetta Hinttala; Reijo Laaksonen; Arto Mannermaa; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Sahar Esmaeeli; Susan Eaton; Sanni Lahdenperä; Janet van Adelsberg; Shameek Biswas; Geoffrey A. Kerchner; Edmond Teng; John Eicher; Vinay Mehta; Padhraig Gormley; Kari Linden; Christopher D. Whelan; Fanli Xu; David Pulford; Martti Färkkilä; Sampsa Pikkarainen; Airi Jussila; Timo Blomster; Mikko Kiviniemi; Markku Voutilainen; Graham Heap; Keith Usiskin; Tim Lu; Danny Oh; Vinay Mehta; Melissa Miller; Xinli Hu; Linda McCarthy; Kari Eklund; Antti Palomäki; Pia Isomäki; Laura Pirilä; Oili Kaipiainen-Seppänen; Johanna Huhtakangas; Bob Georgantas; Apinya Lertratanakul; Marla Hochfeld; Vinay Mehta; Nan Bing; Xinli Hu; Jorge Esparza Gordillo; Nina Mars; Margit Pelkonen; Paula Kauppi; Hannu Kankaanranta; Terttu Harju; David Close; Steven Greenberg; Hubert Chen; Vinay Mehta; Jo Betts; Soumitra Ghosh; Veikko Salomaa; Teemu Niiranen; Markus Juonala; Kaj Metsärinne; Mika Kähönen; Juhani Junttila; Markku Laakso; Jussi Pihlajamäki; Juha Sinisalo; Marja-Riitta Taskinen; Tiinamaija Tuomi; Jari Laukkanen; Ben Challis; Andrew S. Peterson; Audrey Y. Chu; Vinay Mehta; Jaakko Parkkinen; Melissa Miller; Anthony Muslin; Heikki Joensuu; Tuomo Meretoja; Lauri Aaltonen; Annika Auranen; Peeter Karihtala; Saila Kauppila; Päivi Auvinen; Elenius; Relja Popovic; Jeff Waring; Athena Matakidou; Jennifer L. Schutzman; Vinay Mehta; Andrey Loboda; Aparna Chhibber; Heli Lehtonen; Stefan McDonough; Marika Crohns; Diptee Kulkarni; Kai Kaarniranta; Joni A. Turunen; Terhi Ollila; Sanna Seitsonen; Hannu Uusitalo; Vesa Aaltonen; Hannele Uusitalo-Järvinen; Marja Luodonpää; Nina Hautala; Heiko Runz; Erich C. Strauss; Hao Chen; Anna Podgornaia; Vinay Mehta; Joshua Hoffman; Kaisa Tasanen; Laura Huilaja; Katariina Hannula-Jouppi; Teea Salmi; Sirkku Peltonen; Leena Koulu; Ilkka Harvima; Kirsi Kalpala; Ying Wu; David Choy; John Michon; Nizar Smaoui; Fedik Rahimov; Anne Lehtonen; Dawn Waterworth; Justin Wade Davis; Bridget Riley-Gillis; Danjuma Quarless; Slavé Petrovski; Jimmy Liu; Chia-Yen Chen; Paola G. Bronson; Robert Yang; Joseph Maranville; Shameek Biswas; Diana Chang; Julie Hunkapiller; Tushar Bhangale; Natalie Bowers; Dorothée Diogo; Emily Holzinger; Padhraig Gormley; Xulong Wang; Xing Chen; Åsa Hedman; Kirsi Auro; Clarence Wang; Ethan Xu; Franck Auge; Clement Chatelain; Samuli Ripatti; Mark J. Daly; Kimmo Palin; Pietro della Briotta Parolo; Wei Zhou; Manuel Rivas; Aarno Palotie; Andrea Ganna; Vincent Llorens; Antti Karlsson; Mikko Arvas; Kati Hyvärinen; Jarmo Ritari; Tiina Wahlfors; Miika Koskinen; Olli Carpen; Johannes Kettunen; Katri Pylkäs; Marita Kalaoja; Minna Karjalainen; Tuomo Mantere; Eeva Kangasniemi; Sami Heikkinen; Arto Mannermaa; Eija Laakkonen; Juha Kononen; Lila Kallio; Sirpa Soini; Jukka Partanen; Kimmo Pitkänen; Seppo Vainio; Kimmo Savinainen; Veli-Matti Kosma; Teijo Kuopio; Anu Jalanko; Risto Kajanne; Ulrike Lyhs; Mitja Kurki; Juha Karjalainen; Pietro della Briotta Parola; Sina Rüeger; Arto Lehisto; Wei Zhou; Masahiro Kanai; Hannele Laivuori; Tuomo T. J. Kiiskinen; Mari Kaunisto; Jarmo Harju; Elina Kilpeläinen; Georg Brein; Oluwaseun A. Dada; Ghazal Awaisa; Anastasia Shcherban; Timo P. Sipilä; Kati Donner; Anu Loukola; Päivi Laiho; Tuuli Sistonen; Essi Kaiharju; Markku Laukkanen; Elina Järvensivu; Sini Lähteenmäki; Lotta Männikkö; Regis Wong; Hannele Mattsson; Kati Kristiansson; Susanna Lemmelä; Tero Hiekkalinna; Manuel González Jiménez; Priit Palta; Kalle Pärn; Javier Nunez-Fontarnau; Tarja Laitinen; Harri Siirtola; Javier Gracia Tabuenca; Michelle Agee; Babak Alipanahi; Adam Auton; Robert K. Bell; Katarzyna Bryc; Sarah L. Elson; Pierre Fontanillas; Nicholas A. Furlotte; David Hinds; Karen E. Huber; Aaron Kleinman; Nadia K. Litterman; Jennifer C. McCreight; Matthew H. McIntyre; Joanna L. Mountain; Elizabeth S. Noblin; Carrie A.M. Northover; Steven Pitts; J. Fah Sathirapongsasuti; Olga V. Sazonova; Janie F. Shelton; Suyash Shringarpure; Tian; Joyce Y. Tung; Vladimir Vacic; Catherine H. Wilson; Aviv Regev; Aarno Palotie; Neale; John E. Dick; Pradeep Natarajan; Christopher J. O’Donnell; Mark Daly; Michael Milyavsky; Sekar Kathiresan; Vijay G. Sankaran
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A fit for purpose synthesis of Bruton's tyrosine kinase inhibitor GDC-0852
Tetrahedron Letters, ISSN: 18733581 00404039
Ngiap-Kie Lim; Haiming Zhang; C. Gregory Sowell; Francis Gosselin
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Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
Nature, ISSN: 14764687 00280836
Erik L. Bao; Satish K. Nandakumar; Xiaotian Liao; Alexander G. Bick; Marcin Tabaka; Olga I. Gan; Aki S. Havulinna; Caleb A. Lareau; Aitzkoa L. de Lapuente Portilla; Bo Li; Connor Emdin; Veryan Codd; Christopher P. Nelson; Christopher J. Walker; Claire Churchhouse; Albert de la Chapelle; Daryl E. Klein; Björn Nilsson; Peter W. F. Wilson; Kelly Cho; Saiju Pyarajan; J. Michael Gaziano; Nilesh J. Samani; Howard Jacob; Sally John; Robert M. Plenge; Mark I. McCarthy; Caroline Fox; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Jukka Partanen; Anne Pitkäranta; Riitta Kaarteenaho; Urho Kujala; Jimmy Liu; Shameek Biswas; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Call; Kathy Klinger; Matthias Gossel; Johanna Schleutker; Markus Perola; Mikko Arvas; Reetta Hinttala; Reijo Laaksonen; Arto Mannermaa; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Sahar Esmaeeli; Susan Eaton; Sanni Lahdenperä; Janet van Adelsberg; Shameek Biswas; Geoffrey A. Kerchner; Edmond Teng; John Eicher; Padhraig Gormley; Kari Linden; Christopher D. 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Monomeric Targeted Protein Degraders
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Emily J. Hanan; Jun Liang; Xiaojing Wang; Robert A. Blake; Nicole Blaquiere; Steven T. Staben
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Fit-for-purpose synthesis of dual leucine zipper kinase (DLK) inhibitor GNE-834
Tetrahedron Letters, ISSN: 18733581 00404039
Jie Xu; Diane Carrera; Danial Beaudry; Michael Siu; Malcolm P. Huestis; Wendy Liu; Remy Angelaud; Francis Gosselin
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Dimerization Induced by C-Terminal 14-3-3 Binding Is Sufficient for BRAF Kinase Activation
Biochemistry, ISSN: 15204995 00062960
Nicholas P. D. Liau; Avinashnarayan Venkatanarayan; John Quinn; Wilson Phung; Shiva Malek; Sarah G. Hymowitz; Jawahar Sudhamsu
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Optimization of globomycin analogs as novel gram-negative antibiotics
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Keira Garland; Homer Pantua; Marie-Gabrielle Braun; Burdick; Georgette M. Castanedo; Yi-Chen Chen; Yun-Xing Cheng; Jonathan Cheong; Blake E. Daniels; Gauri Deshmukh; Yuhong Fu; Paul Gibbons; Susan L. Gloor; Rongbao Hua; Sharada Labadie; Xiongcai Liu; Richard Pastor; Craig E. Stivala; Min Xu; Yiming Xu; Hao Zheng; Sharookh B. Kapadia; Emily J. Hanan
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Exposure-safety and exposure-efficacy analyses of polatuzumab vedotin in patients with relapsed or refractory diffuse large B-cell lymphoma
Leukemia and Lymphoma, ISSN: 10292403 10428194
Tong Lu; Leonid Gibiansky; Xiaobin Li; Chunze Li; Rong Shi; Priya Agarwal; Jamie Hirata; Dale Miles; Pascal Chanu; Sandhya Girish; Jin Yan Jin; Dan Lu
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