Scientists / Publications

Publications

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DISPLAYING 4301 - 4350 OF 15217 RESULTS

Trastuzumab emtansine versus taxane use for previously treated HER2-positive locally advanced or metastatic gastric or gastro-oesophageal junction adenocarcinoma (GATSBY): an international randomised, open-label, adaptive, phase 2/3 study
The Lancet Oncology, ISSN: 14745488 14702045
Peter C Thuss-Patience; Manish A. Shah; Atsushi Ohtsu; Eric Van Cutsem; Jaffer A. Ajani; Hugo Castro; Wasat Mansoor; Hyun Cheol Chung; Gyorgy Bodoky; Kohei Shitara; Gail L. Phillips; Tina van der Horst; Marie-Laurence Harle-Yge; Betsy Althaus; Yoon-Koo Kang
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Novel mechanism of decyanation of GDC-0425 by cytochrome P450
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Ryan Takahashi; Jason S Halladay; Michael Siu; Yuan Chen; Cornelis E. Hop; S. Cyrus Khojasteh; Shuguang Ma
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Evaluation of heavy chain C-terminal deletions on productivity and product quality of monoclonal antibodies in Chinese hamster ovary (CHO) cells
Biotechnology Progress, ISSN: 15206033 87567938
Zhilan Hu; Danming Tang; Shahram Misaghi; Guoying Jiang; X. Christopher Yu; Mandy Yim; David Shaw; Snedecor; Mike Laird; Amy Shen
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The Clinical Importance of Changes in Diabetic Retinopathy Severity Score
Ophthalmology, ISSN: 15494713 01616420
Michael S. Ip; Jiameng Zhang; Jason S. Ehrlich
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Seasonal variability of severe asthma exacerbations and clinical benefit from lebrikizumab
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Tracy Staton; Joseph R. Arron; Julie Olsson; Cécile T.J. Holweg; Matthews; David F. Choy
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Impact of physiologically based pharmacokinetic models on regulatory reviews and product labels: Frequent utilization in the field of oncology
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Yoshida; Nageshwar Budha; Jin Y. Jin
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Activity-based probes for the ubiquitin conjugation–deconjugation machinery: new chemistries, new tools, and new insights
FEBS Journal, ISSN: 17424658 1742464X
David S. Hewings; Flygare; Matthew Bogyo; Ingrid E. Wertz
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Melt extrusion vs. spray drying: The effect of processing methods on crystalline content of naproxen-povidone formulations
European Journal of Pharmaceutical Sciences, ISSN: 18790720 09280987
Abbe Haser; Tu Cao; Joseph W. Lubach; Tony Listro; Larry Acquarulo; Feng Zhang
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Reply
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Phillip Lieberman; Dale T. Umetsu; Gillis Carrigan; Abdelkader Rahmaoui
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Assessment of Correlation Between Early and Late Efficacy Endpoints to Identify Potential Surrogacy Relationships in Non-Hodgkin Lymphoma: a Literature-Based Meta-analysis of 108 Phase II and Phase III Studies
AAPS Journal, ISSN: 15507416
Rui Zhu; Dan Lu; Yu-Waye Chu; Akiko Chai; Michelle Green; Nancy Zhang; Jin Y. Jin
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Activity-based probes for the multicatalytic proteasome
FEBS Journal, ISSN: 17424658 1742464X
David S. Hewings; Flygare; Ingrid E. Wertz; Matthew Bogyo
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Longitudinal variation of serum periostin levels in adults with stable asthma
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Ruth Semprini; Caswell-Smith; James Fingleton; Cécile T.J. Holweg; Matthews; Mark Weatherall; Beasley; Irene Braithwaite
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Cardiovascular and cerebrovascular events among patients receiving omalizumab: Pooled analysis of patient-level data from 25 randomized, double-blind, placebo-controlled clinical trials
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Carlos Iribarren; Kenneth J. Rothman; Mary S. Bradley; Gillis Carrigan; Mark D. Eisner; Hubert Chen
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Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study in moderate to severe asthma
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Carlos Iribarren; Abdelkader Rahmaoui; Aidan Long; Stanley J. Szefler; Mary S. Bradley; Gillis Carrigan; Mark D. Eisner; Hubert Chen; Theodore A. Omachi; Michael E. Farkouh; Kenneth J. Rothman
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Patient and physician preferences for anticancer drugs for the treatment of metastatic colorectal cancer: A discrete-choice experiment
Cancer Management and Research, ISSN: 11791322
Juan Marcos González; Sarika Ogale; Rob Morlock; Joshua Posner; A. Brett Hauber; Nicolas Sommer; Grothey
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NPTX2 and cognitive dysfunction in Alzheimer’s Disease
eLife, ISSN: 2050084X
Mei-Fang Xiao; Desheng Xu; Michael T Craig; Kenneth A Pelkey; Chun-Che Chien; Yang Shi; Juhong Zhang; Susan Resnick; Olga Pletnikova; David Salmon; James Brewer; Steven Edland; Jerzy Wegiel; Benjamin Tycko; Alena Savonenko; Roger H. Reeves; Juan C. Troncoso; Chris J. McBain; Douglas Galasko; Paul F Wegiel
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Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult
eLife, ISSN: 2050084X
Martin Larhammar; Sarah Huntwork-Rodriguez; Zhiyu Jiang; Hilda Solanoy; Arundhati Sengupta Ghosh; Bei Wang; Joshua S. Kaminker; Kevin Huang; Jeffrey Eastham-Anderson; Michael Siu; Zora Modrusan; Madeline M. Farley; Marc Tessier-Lavigne; Joe Lewcock; Trent A. Watkins
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Highly Regioselective and Practical Synthesis of 5-Bromo-4-chloro-3-nitro-7-azaindole
Organic Process Research and Development, ISSN: 1520586X 10836160
Chong Han; Keena L. Green; Eugen Pfeifer; Francis Gosselin
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Highly Regioselective and Practical Synthesis of 5-Bromo-4-chloro-3-nitro-7-azaindole
Organic Process Research and Development, ISSN: 10836160
Chong Han; Keena L. Green; Eugen Pfeifer; Francis Gosselin
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A Novel Cascade Benzyne Nucleophilic Addition/Fries Rearrangement for Entry into 2,3-Disubstituted Phenols
Synlett, ISSN: 14372096 09365214
Sarah M. Bronner; Daniel Lee; Vlad Bacauanu; Patrick Cyr
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The Janus Kinase (JAK) FERM and SH2 domains: Bringing specificity to JAK-receptor interactions
Frontiers in Endocrinology, ISSN: 16642392
Ryan Ferrao; Patrick J. Lupardus
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The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation
Science Signaling, ISSN: 19379145 19450877
Kate Senger; Victoria Pham; Eugene Varfolomeev; Jason A. Hackney; Cesar A. Corzo; Jenna L. Collier; Vivian W. C. Lau; Zhiyu Huang; Kajal Hamidzhadeh; Patrick Caplazi; Ivan Peng; A F. Setiadi; Ross Francis; Andres Paler Martinez; Youngsu C. Kwon; Vladimir Ramirez-Carrozzi; Yonglian Sun; Patricia W. Grigg; Merone Roose-Girma; Surinc Er Jeet; Kai H. Barck; Anna Pham; Naruhisa Ota; Connie Ha; Stinson; Joseph Guillory; Lucinda Tam; Zora Modrusan; Claire Emson; Brent Mckenzie; Michael J. Townsend; Richard A. D. Carano; Søren Warming; Domagoj Vucic; Jason De Voss; Wyne P. Lee; Jennie R. Lill; Ali A. Zarrin
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The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation
Science Signaling, ISSN: 19450877
Kate Senger; Victoria Pham; Eugene Varfolomeev; Jason A. Hackney; Cesar A. Corzo; Jenna L. Collier; Vivian W. C. Lau; Zhiyu Huang; Kajal Hamidzhadeh; Patrick Caplazi; Ivan Peng; A F. Setiadi; Ross Francis; Andres Paler Martinez; Youngsu C. Kwon; Vladimir Ramirez-Carrozzi; Yonglian Sun; Patricia W. Grigg; Merone Roose-Girma; Surinc Er Jeet; Kai H. Barck; Anna Pham; Ota; Connie Ha; Stinson; Joseph Guillory; Lucinda Tam; Zora Modrusan; Claire Emson; Brent S. McKenzie; Michael J. Townsend; Richard A. D. Carano; Søren Warming; Domagoj Vucic; Jason De Voss; Wyne P. Lee; Jennie R. Lill; Ali A. Zarrin
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Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Aaron H Nile; Susmith Mukund; Karen Stanger; Weiru Wang; Rami N. Hannoush
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The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation
Science Signaling, ISSN: 19379145 19450877
Kate Senger; Victoria Pham; Eugene Varfolomeev; Jason A. Hackney; Cesar A. Corzo; Jenna L. Collier; Vivian W. C. Lau; Zhiyu Huang; Kajal Hamidzadeh; Patrick Caplazi; Ivan Peng; A F. Setiadi; Ross Francis; Andres Paler Martinez; Youngsu C. Kwon; Vladimir Ramirez-Carrozzi; Yonglian Sun; Patricia W. Grigg; Merone Roose-Girma; Surinc Er Jeet; Kai H. Barck; Anna Pham; Naruhisa Ota; Connie Ha; Stinson; Joseph Guillory; Lucinda Tam; Zora Modrusan; Claire Emson; Brent Mckenzie; Michael J. Townsend; Richard A. D. Carano; Søren Warming; Domagoj Vucic; Jason De Voss; Wyne P. Lee; Jennie R. Lill; Ali A. Zarrin
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A CEACAM6-high airway neutrophil phenotype and CEACAM6-high epithelial cells are features of severe asthma
Journal of Immunology, ISSN: 15506606 00221767
Aarti Shikotra; David F. Choy; Salman Siddiqui; Greer Arthur; Deepti R. Nagarkar; Guiquan Jia; Adam K. A. Wright; Chandra M. Ohri; Emma Doran; Claire A. Butler; Beverley Hargadon; Abbas Alexander; Janet Jackman; Lawren C. Wu; Liam G. Heaney; Joseph R. Arron; Peter Bradding
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Compatibility study of a parenteral microdose polyethylene glycol formulation in medical devices and identification of degradation impurity by 2D-LC/MS
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Lulu Dai; Geoffrey K. Yeh; Yingqing Ran; Peter M. Yehl; Kelly Zhang
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Transcription factor Etv5 is essential for the maintenance of alveolar type II cells
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Zhen Zhang; Kim Newton; Sarah K. Kummerfeld; Webster; Donald S. Kirkpatrick; Lilian Phu; Jeffrey Eastham-Anderson; Jinfeng Liu; Wyne P. Lee; Jiansheng Wu; Hong Li; Melissa Junttila; Vishva M. Dixit
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Genomics and evolution of protein phosphatases
Science Signaling, ISSN: 19379145 19450877
Mark J. Chen; Jack E. Dixon; Gerard Manning
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Validation of a two-dimensional liquid chromatography method for quality control testing of pharmaceutical materials
Journal of Chromatography A, ISSN: 18733778 00219673
Samuel H. Yang; Jennifer Wang; Kelly Zhang
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Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell–associated damage in IFNα-driven lupus nephritis
JCI insight, ISSN: 23793708
Arna Katewa; Yugang Wang; Jason A. Hackney; Tao Huang; Eric Suto; Nandhini Ramamoorthi; Cary D. Austin; Meire C. Bremer; Jacob Z. Chen; James J. Crawford; Kevin S. Currie; Peter Blomgren; Jason Devoss; Julie Dipaolo; Jonathan Hau; Adam R. Johnson; Justin Lesch; Laura DeForge; Zhonghua Lin; Marya Liimatta; Joseph W. Lubach; Sami McVay; Zora Modrusan; Allen Nguyen; Chungkee Poon; Jianyong Wang; Lichuan Liu; Wyne P. Lee; Harvey Wong; Wendy B. Young; Michael J. Townsend; Karin Reif
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Computationally Discovered Potentiating Role of Glycans on NMDA Receptors
Scientific Reports, ISSN: 20452322
Anton V. Sinitskiy; Nathaniel H. Stanley; David Hackos; Jesse E. Hanson; Benjamin D. Sellers; Vijay S. Pande
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Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands
Journal of Clinical Investigation, ISSN: 15588238 00219738
Jooho Chung; Christen Ebens; Eric Perkey; Vedran Radojcic; Ute Koch; Leonardo Scarpellino; Alexander Tong; Frederick Allen; Sherri Wood; Jiane Feng; Ann Friedman; David Granadier; Ivy T. Tran; Qian Chai; Lucas Onder; Minhong Yan; Pavan Reddy; Bruce R. Blazar; Alex Y. Huang; Todd V. Brennan; D. Keith Bishop; Burkhard Ludewig; Christian W. Siebel; Freddy Radtke; Sanjiv A. Luther; Ivan Maillard
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bisFabs: Tools for rapidly screening hybridoma IgGs for their activities as bispecific antibodies
mAbs, ISSN: 19420870 19420862
Sanket Patke; Ji Li; Peiyin Wang; Dionysos S. Slaga; Jennifer A. Johnston; Sunil Bhakta; Siler Panowski; Liping L. Sun; Teemu T. Junttila; Justin M. Scheer; Diego Ellerman
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[18F] Positron emission tomography response after rituximab-containing induction therapy in follicular lymphoma is an independent predictor of survival after adjustment for FLIPI in academic and community-based practice
Leukemia and Lymphoma, ISSN: 10292403 10428194
Ida Wong-Sefidan; Michelle Byrtek; Zhou; Jonathan W. Friedberg; Christopher R. Flowers; Zelenetz; Keith Dawson; Erin G. Reid
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Staphylococcus aureus type I signal peptidase: Essential or not essential, that’s the question
Microbial Cell, ISSN: 23112638
Wouter L. W. Hazenbos; Elizabeth Skippington; Man-Wah Tan
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Preference for subcutaneous or intravenous administration of rituximab among patients with untreated CD20+ diffuse large B-cell lymphoma or follicular lymphoma: Results from a prospective, randomized, open-label, crossover study (PrefMab)
Annals of Oncology, ISSN: 15698041 09237534
Rummel; Kim; Aversa; Wolfram Brugger; Capochiani; Plenteda; Re; Peter C. Trask; Osborne; Smith; Grigg
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Incidence and management of diarrhea in patients with HER2-positive breast cancer treated with pertuzumab
Annals of Oncology, ISSN: 15698041 09237534
Sandra M. Swain; Andreas Schneeweiss; Luca Gianni; Gao; Alisha Stein; Waldron-Lynch; Sarah Heeson; Beattie; Bongin Yoo; Javier Cortés; Baselga
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Response to "quantitative Prediction of Drug-Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is It Worth?"
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Ian E. Templeton; Yuan Chen; Jialin Mao; Jian Lin; Hongbin Yu; Peters; Shebley; Varma
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Response to "quantitative Prediction of Drug-Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is It Worth?"
CPT: Pharmacometrics and Systems Pharmacology,
Ian E. Templeton; Yuan Chen; Jialin Mao; Lin; Hongbin Yu; Peters; Shebley; Varma
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Importance of angioedema-free days in patients with chronic idiopathic or spontaneous urticaria
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
James L. Zazzali; Allen P. Kaplan; Marcus Maurer; Karina Raimundo; Benjamin L. Trzaskoma; Evgeniya Antonova; Karin Rosén
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Ras-MEK signaling mediates a critical Chk1-dependent DNA damage response in cancer cells
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Ho-June Lee; Yi Cao; Victoria Pham; Elizabeth M. Blackwood; Catherine Wilson; Marie Evangelista; Christiaan N. Klijn; David Stokoe; Jeffrey Settleman
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Tools for communication: Novel infrastructure to address patient-perceived gaps in oncology care
Clinical journal of oncology nursing, ISSN: 1538067X 10921095
Suzanne McMullen; Shelagh Szabo; Ronald J. Halbert; Catherine Lai; Aparna R. Parikh; Mikele M. Bunce; Raya Khoury; Anthony Masaquel
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Dying cells actively regulate adaptive immune responses
Nature Reviews Immunology, ISSN: 14741741 14741733
Nader Yatim; Sean P. Cullen; Matthew L. Albert
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Effect of Omalizumab on Blood Basophil Counts in Patients with Chronic Idiopathic/Spontaneous Urticaria
Journal of Investigative Dermatology, ISSN: 15231747 0022202X
Sarbjit S. Saini; Theodore A. Omachi; Benjamin L. Trzaskoma; Henry N. Hulter; Karin Rosén; Patricia M. Sterba; Jean-Paul Courneya; Alan Lackey; Hubert Chen
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Reversible phosphorylation of the 26S proteasome
Protein and Cell, ISSN: 16748018 1674800X
Xing Guo; Xiuliang Huang; Mark J. Chen
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From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors
Nature Reviews Drug Discovery, ISSN: 14741784 14741776
Avi Ashkenazi; Wayne J. Fairbrother; Joel D. Leverson; Andrew J. Souers
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Control Strategies for Drug Product Continuous Direct Compression—State of Control, Product Collection Strategies, and Startup/Shutdown Operations for the Production of Clinical Trial Materials and Commercial Products
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Ahmad Almaya; Lawrence De Belder; Robert Meyer; Karthik Nagapudi; Hung-Ren Homer Lin; Ian Leavesley; Jayanthy Jayanth; Gurjit Bajwa; James DiNunzio; Anthony Tantuccio; Dan Blackwood; Admassu Abebe
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Recent Insights into the Molecular Mechanisms Underlying Pyroptosis and Gasdermin Family Functions
Trends in Immunology, ISSN: 14714981 14714906
Robin A. Aglietti; Erin C. Dueber
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Characterization of PD-L1 expression and immune cell infiltration in nasopharyngeal cancer
Oral Oncology, ISSN: 18790593 13688375
Oscar Siu Hong Chan; Marcin Kowanetz; Wai Tong Ng; Koeppen; Lai Kwan Chan; Rebecca Mei Wan Yeung; Haiyan Wu; Lukas Amler; Christoph Mancao
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